VOLUME 6 (2015)
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Fixed cerebral cortex of E14.5 c-fos+/+ and c-fos -/- embryos were stained with DAPI and examined under a confocal microscope. Boxes in red represent the areas used for the quantifications shown in B. See Velazquez et al.
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Table of Contents
Editorial
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| mTORC1 sustains vision in retinitis pigmentosa |
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https://doi.org/10.18632/oncotarget.4466
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| 16786-16787 |
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| Specificity and diversity of the mouse Peyer’s patch mononuclear phagocyte system |
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https://doi.org/10.18632/oncotarget.4481
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| 16788-16789 |
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| Rejuvenation by inhibiting TGFβ1/pSmad signaling |
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https://doi.org/10.18632/oncotarget.4563
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| 16790-16791 |
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| The APC/C and CK1 in the developing brain |
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https://doi.org/10.18632/oncotarget.4797
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| 16792-16793 |
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| Aging phenomics enabled by quantitative imaging analysis |
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https://doi.org/10.18632/oncotarget.4566
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| 16794-16795 |
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| The higherorder molecular organization of p62/SQSTM1 |
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https://doi.org/10.18632/oncotarget.4590
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| 16796-16797 |
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| Infectious origins of childhood leukemia |
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https://doi.org/10.18632/oncotarget.4630
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| 16798-16799 |
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| Mitochondriolus: assembling mitoribosomes |
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https://doi.org/10.18632/oncotarget.4646
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| 16800-16801 |
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| IRX1 hypomethylation in osteosarcoma metastasis |
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https://doi.org/10.18632/oncotarget.4696
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| 16802-16803 |
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| LKB1 in transmembrane receptor signaling |
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https://doi.org/10.18632/oncotarget.4777
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| 16804-16805 |
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| The MIOREX complex lean management of mitochondrial gene expression |
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https://doi.org/10.18632/oncotarget.4783
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| 16806-16807 |
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| Geneticallyencoded sensors of protein hydrodynamics |
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https://doi.org/10.18632/oncotarget.4785
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| 16808-16809 |
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| mTORtuous effect on the elastic heart |
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https://doi.org/10.18632/oncotarget.4788
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| 16810-16811 |
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| Redefining protein moonlighting |
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https://doi.org/10.18632/oncotarget.4793
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| 16812-16813 |
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| Sirtuin 3 in acute kidney injury |
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https://doi.org/10.18632/oncotarget.4794
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| 16814-16815 |
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| Protein quality and quantity control at the yeast ER |
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https://doi.org/10.18632/oncotarget.4855
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| 16818-16819 |
Editorial: Pathology
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| Physiologically distinct neuronal type in primate cortex |
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https://doi.org/10.18632/oncotarget.4796
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| 16820-16821 |
Editorial: Chromosome
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| Mps1Ndc80: one interaction to rule them all |
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https://doi.org/10.18632/oncotarget.4837
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| 16822-16823 |
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| Plant immune receptors mimic pathogen virulence targets |
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https://doi.org/10.18632/oncotarget.4838
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| 16824-16825 |
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| Antimicrobial peptides target ribosomes |
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https://doi.org/10.18632/oncotarget.4839
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| 16826-16827 |
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| DNA repair: Location location location |
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https://doi.org/10.18632/oncotarget.4840
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| 16828-16829 |
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| ETV6 mutations define a new cancer predisposition syndrome |
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https://doi.org/10.18632/oncotarget.4842
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| 16830-16831 |
Reviews
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| Targeting cancer cell metabolism in pancreatic adenocarcinoma |
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https://doi.org/10.18632/oncotarget.4160
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| 16832-16847 |
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| Reactive oxygen species a doubleedged sword for mesothelioma |
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https://doi.org/10.18632/oncotarget.4253
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| 16848-16865 |
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| Circadian disruption and breast cancer: An epigenetic link |
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https://doi.org/10.18632/oncotarget.4343
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| 16866-16882 |
Priority Research Papers
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| Brain development is impaired in cfos / mice |
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https://doi.org/10.18632/oncotarget.4527
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| 16883-16901 |
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| ErbB3 activation by NRG1β sustains growth and promotes vemurafenib resistance in BRAFV600E colon cancer stem cells CSCs |
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https://doi.org/10.18632/oncotarget.4642
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| 16902-16911 |
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| Cyclin E/Cdk2dependent phosphorylation of Mcl1 determines its stability and cellular sensitivity to BH3 mimetics |
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https://doi.org/10.18632/oncotarget.4857
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| 16912-16925 |
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| Antitumoral effect of desmethylclomipramine in lung cancer stem cells |
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https://doi.org/10.18632/oncotarget.4700
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| 16926-16938 |
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| SUV39H2 methylates and stabilizes LSD1 by inhibiting polyubiquitination in human cancer cells |
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https://doi.org/10.18632/oncotarget.4760
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| 16939-16950 |
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| Highthroughput simultaneous screen and counterscreen identifies homoharringtonine as synthetic lethal with von HippelLindau loss in renal cell carcinoma |
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https://doi.org/10.18632/oncotarget.4773
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| 16951-16962 |
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| p53 amplifies Tolllike receptor 5 response in human primary and cancer cells through interaction with multiple signal transduction pathways |
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https://doi.org/10.18632/oncotarget.4435
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| 16963-16980 |
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| A highthroughput kinome screen reveals serum/glucocorticoidregulated kinase 1 as a therapeutic target for NF2deficient meningiomas |
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https://doi.org/10.18632/oncotarget.4858
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| 16981-16997 |
Research Papers: Gerotarget (Focus on Aging)
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| Effects of eight weeks of aerobic interval training and of isoinertial resistance training on risk factors of cardiometabolic diseases and exercise capacity in healthy elderly subjects |
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https://doi.org/10.18632/oncotarget.4031
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| 16998-17015 |
Research Papers: Pathology
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| Deletion of Smad3 improves cardiac allograft rejection in mice |
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https://doi.org/10.18632/oncotarget.4849
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| 17016-17030 |
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| A comprehensive study of the association between drug hepatotoxicity and daily dose liver metabolism and lipophilicity using 975 oral medications |
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https://doi.org/10.18632/oncotarget.4400
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| 17031-17038 |
Research Papers
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| Involvement of Ras GTPaseactivating protein SH3 domainbinding protein 1 in the epithelialtomesenchymal transitioninduced metastasis of breast cancer cells via the Smad signaling pathway |
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https://doi.org/10.18632/oncotarget.3636
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| 17039-17053 |
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| Agerelated changes in monocytes exacerbate neointimal hyperplasia after vascular injury |
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https://doi.org/10.18632/oncotarget.3881
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| 17054-17064 |
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| Transcriptome profiling of esophageal squamous cell carcinoma reveals a long noncoding RNA acting as a tumor suppressor |
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https://doi.org/10.18632/oncotarget.4185
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| 17065-17080 |
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| Melatonin antiproliferative effects require active mitochondrial function in embryonal carcinoma cells |
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https://doi.org/10.18632/oncotarget.4012
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| 17081-17096 |
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| MicroRNA analysis suggests an additional level of feedback regulation in the NFκB signaling cascade |
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https://doi.org/10.18632/oncotarget.4005
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| 17097-17106 |
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| Inhibition of histamine receptor 3 suppresses glioblastoma tumor growth invasion and epithelialtomesenchymal transition |
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https://doi.org/10.18632/oncotarget.3672
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| 17107-17120 |
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| SNAI2/Slug gene is silenced in prostate cancer and regulates neuroendocrine differentiation metastasissuppressor and pluripotency gene expression |
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https://doi.org/10.18632/oncotarget.2736
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| 17121-17134 |
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| Improvement of DC vaccine with ALAPDT induced immunogenic apoptotic cells for skin squamous cell carcinoma |
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https://doi.org/10.18632/oncotarget.3529
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| 17135-17146 |
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| The novel dual PI3K/mTOR inhibitor NVPBGT226 displays cytotoxic activity in both normoxic and hypoxic hepatocarcinoma cells |
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https://doi.org/10.18632/oncotarget.3940
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| 17147-17160 |
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| 3’Phosphoadenosine 5’phosphosulfate synthase 1 PAPSS1 knockdown sensitizes nonsmall cell lung cancer cells to DNA damaging agents |
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https://doi.org/10.18632/oncotarget.3635
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| 17161-17177 |
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| Radiosensitization and downregulation of heterogeneous nuclear ribonucleoprotein K hnRNP K upon inhibition of mitogen/extracellular signalregulated kinase MEK in malignant melanoma cells |
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https://doi.org/10.18632/oncotarget.3935
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| 17178-17191 |
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| Mitochondrial p53 phosphorylation induces Bakmediated and caspaseindependent cell death |
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https://doi.org/10.18632/oncotarget.3780
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| 17192-17205 |
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| YAP is a critical oncogene in human cholangiocarcinoma |
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https://doi.org/10.18632/oncotarget.4043
|
| 17206-17220 |
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| TRPM8 channel as a novel molecular target in androgenregulated prostate cancer cells |
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https://doi.org/10.18632/oncotarget.3948
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| 17221-17236 |
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| Insulin/IGF1PI3Kdependent nucleolar localization of a glycolytic enzyme – phosphoglycerate mutase 2 is necessary for proper structure of nucleolus and RNA synthesis |
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https://doi.org/10.18632/oncotarget.4044
|
| 17237-17250 |
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| Pharmacogenomic analysis indicates potential of 15isoquinolinediol as a universal antiaging agent for different tissues |
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https://doi.org/10.18632/oncotarget.3949
|
| 17251-17260 |
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| Peritoneal tumor spread in serous ovarian cancerepithelial mesenchymal status and outcome |
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https://doi.org/10.18632/oncotarget.3746
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| 17261-17275 |
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| Overexpression of Id1 in transgenic mice promotes mammary basal stem cell activity and breast tumorigenesis |
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https://doi.org/10.18632/oncotarget.3640
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| 17276-17290 |
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| FGF23 promotes prostate cancer progression |
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https://doi.org/10.18632/oncotarget.4174
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| 17291-17301 |
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| TLR9 signaling through NFκB/RELA and STAT3 promotes tumorpropagating potential of prostate cancer cells |
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https://doi.org/10.18632/oncotarget.4029
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| 17302-17313 |
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| The combination of HDAC and aminopeptidase inhibitors is highly synergistic in myeloma and leads to disruption of the NFκB signalling pathway |
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https://doi.org/10.18632/oncotarget.1168
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| 17314-17327 |
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| Marine alkaloid Monanchocidin a overcomes drug resistance by induction of autophagy and lysosomal membrane permeabilization |
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https://doi.org/10.18632/oncotarget.4175
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| 17328-17341 |
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| Deregulation of HMGA1 expression induces chromosome instability through regulation of spindle assembly checkpoint genes |
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https://doi.org/10.18632/oncotarget.3944
|
| 17342-17353 |
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| Prognostic role of IDH mutations in gliomas: a metaanalysis of 55 observational studies |
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https://doi.org/10.18632/oncotarget.4008
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| 17354-17365 |
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| MicroRNA125a influences breast cancer stem cells by targeting leukemia inhibitory factor receptor which regulates the hippo signaling pathway |
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https://doi.org/10.18632/oncotarget.3953
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| 17366-17378 |
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| Novel roles of TMEM100: inhibition metastasis and proliferation of hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.3954
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| 17379-17390 |
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| Sp1driven upregulation of miR19a decreases RHOB and promotes pancreatic cancer |
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https://doi.org/10.18632/oncotarget.3975
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| 17391-17403 |
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| MiR3615p inhibits colorectal and gastric cancer growth and metastasis by targeting staphylococcal nuclease domain containing1 |
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https://doi.org/10.18632/oncotarget.3744
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| 17404-17416 |
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| TATODDp53 enhances the radiosensitivity of hypoxic breast cancer cells by inhibiting Parkinmediated mitophagy |
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https://doi.org/10.18632/oncotarget.4002
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| 17417-17429 |
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| C/Dbox snoRNAderived RNA production is associated with malignant transformation and metastatic progression in prostate cancer |
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https://doi.org/10.18632/oncotarget.4172
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| 17430-17444 |
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| HGFL supports mammary tumorigenesis by enhancing tumor cell intrinsic survival and influencing macrophage and Tcell responses |
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https://doi.org/10.18632/oncotarget.3641
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| 17445-17461 |
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| CD4+ and CD8+ T cells have opposing roles in breast cancer progression and outcome |
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https://doi.org/10.18632/oncotarget.3958
|
| 17462-17478 |
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| RhoE is required for contact inhibition and negatively regulates tumor initiation and progression |
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https://doi.org/10.18632/oncotarget.4127
|
| 17479-17490 |
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| EGFR tyrosine kinase inhibitors promote procaspase8 dimerization that sensitizes cancer cells to DNAdamaging therapy |
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https://doi.org/10.18632/oncotarget.3959
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| 17491-17500 |
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| Endothelial Rac1 is essential for hematogenous metastasis to the lung |
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https://doi.org/10.18632/oncotarget.3766
|
| 17501-17513 |
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| The vacuolar H+ ATPase is a novel therapeutic target for glioblastoma |
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https://doi.org/10.18632/oncotarget.4239
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| 17514-17531 |
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| The novel proteasome inhibitor carfilzomib activates and enhances extrinsic apoptosis involving stabilization of death receptor 5 |
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https://doi.org/10.18632/oncotarget.3947
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| 17532-17542 |
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| Wholeexome sequencing of primary plasma cell leukemia discloses heterogeneous mutational patterns |
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https://doi.org/10.18632/oncotarget.4028
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| 17543-17558 |
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| By downregulating TIAM1 expression microRNA329 suppresses gastric cancer invasion and growth |
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https://doi.org/10.18632/oncotarget.2755
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| 17559-17569 |
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| Aberrant activation of Wnt/βcatenin signaling drives proliferation of bone sarcoma cells |
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https://doi.org/10.18632/oncotarget.4100
|
| 17570-17583 |
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| UXT a novel MDMXbinding protein promotes glycolysis by mitigating p53mediated restriction of NFκB activity |
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https://doi.org/10.18632/oncotarget.3770
|
| 17584-17593 |
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| NDRG4 is a novel oncogenic protein and p53 associated regulator of apoptosis in malignant meningioma cells |
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https://doi.org/10.18632/oncotarget.4009
|
| 17594-17604 |
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| Enzastaurin inhibits ABCB1mediated drug efflux independently of effects on protein kinase C signalling and the cellular p53 status |
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https://doi.org/10.18632/oncotarget.2889
|
| 17605-17620 |
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| Combined estrogenic and antiestrogenic properties of estetrol on breast cancer may provide a safe therapeutic window for the treatment of menopausal symptoms |
|
https://doi.org/10.18632/oncotarget.4184
|
| 17621-17636 |
|
| AKAP4 is a circulating biomarker for nonsmall cell lung cancer |
|
https://doi.org/10.18632/oncotarget.3946
|
| 17637-17647 |
|
| Attenuated mutant strain of Salmonella Typhimurium lacking the ZnuABC transporter contrasts tumor growth promoting anticancer immune response |
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https://doi.org/10.18632/oncotarget.3893
|
| 17648-17660 |
|
| Histone demethylase RBP2 promotes malignant progression of gastric cancer through TGFβ1pSmad3RBP2EcadherinSmad3 feedback circuit |
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https://doi.org/10.18632/oncotarget.3756
|
| 17661-17674 |
|
| CEMTDD: The database for elucidating the relationships among herbs compounds targets and related diseases for Chinese ethnic minority traditional drugs |
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https://doi.org/10.18632/oncotarget.3789
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| 17675-17684 |
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| The interplay between TEAD4 and KLF5 promotes breast cancer partially through inhibiting the transcription of p27Kip1 |
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https://doi.org/10.18632/oncotarget.3779
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| 17685-17697 |
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| BET inhibitor OTX015 targets BRD2 and BRD4 and decreases cMYC in acute leukemia cells |
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https://doi.org/10.18632/oncotarget.4131
|
| 17698-17712 |
|
| Identification and evaluation of network modules for the prognosis of basallike breast cancer |
|
https://doi.org/10.18632/oncotarget.4034
|
| 17713-17724 |
|
| Regulation of VCP/p97 demonstrates the critical balance between cell death and epithelialmesenchymal transition EMT downstream of ER stress |
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https://doi.org/10.18632/oncotarget.3918
|
| 17725-17737 |
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| Lapatinib promotes the incidence of hepatotoxicity by increasing chemotherapeutic agent accumulation in hepatocytes |
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https://doi.org/10.18632/oncotarget.3921
|
| 17738-17752 |
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| miR514a regulates the tumour suppressor NF1 and modulates BRAFi sensitivity in melanoma |
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https://doi.org/10.18632/oncotarget.3924
|
| 17753-17763 |
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| Genetic alterations of JAK/STAT cascade and histone modification in extranodal NK/Tcell lymphoma nasal type |
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https://doi.org/10.18632/oncotarget.3776
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| 17764-17776 |
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| Purification and identification of a polysaccharide from medicinal mushroom Amauroderma rude with immunomodulatory activity and inhibitory effect on tumor growth |
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https://doi.org/10.18632/oncotarget.4397
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| 17777-17791 |
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| Thioredoxin reductase: A novel independent prognostic marker in patients with hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.3785
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| 17792-17804 |
|
| Loss of tumor suppressive microRNA31 enhances TRADD/NFκB signaling in glioblastoma |
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https://doi.org/10.18632/oncotarget.4596
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| 17805-17816 |
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| CCAR2/DBC1 is required for Chk2dependent KAP1 phosphorylation and repair of DNA damage |
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https://doi.org/10.18632/oncotarget.4417
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| 17817-17831 |
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| Ergosterol purified from medicinal mushroom Amauroderma rude inhibits cancer growth in vitro and in vivo by upregulating multiple tumor suppressors |
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https://doi.org/10.18632/oncotarget.4026
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| 17832-17846 |
Case Reports
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| ERCPinduced duodenal perforation successfully treated with endoscopic pursestring suture: a case report |
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https://doi.org/10.18632/oncotarget.4079
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| 17847-17850 |
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