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Akwasi et al show the computational docking of GANT61 to GLI1 using the known crystal structure of the five zinc finger GLI1-DNA complex.
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Table of Contents
Reviews
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| An updated overview of HPVassociated head and neck carcinomas |
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https://doi.org/10.18632/oncotarget.1934
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| 3956-3969 |
Research Perspectives
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| The nutritional phenome of EMTinduced cancer stemlike cells |
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https://doi.org/10.18632/oncotarget.2147
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| 3970-3982 |
Priority Research Papers
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| Influence of tumor microenvironment on prognosis in colorectal cancer: Tissue architecturedependent signature of endosialin TEM1 and associated proteins |
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https://doi.org/10.18632/oncotarget.2108
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| 3983-3995 |
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| Combined BRAFV600E and SRCinhibition induces apoptosis evokes an immune response and reduces tumor growth in an immunocompetent orthotopic mouse model of anaplastic thyroid cancer |
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https://doi.org/10.18632/oncotarget.2130
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| 3996-4010 |
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| An interferon signature identified by RNAsequencing of mammary tissues varies across the estrous cycle and is predictive of metastasisfree survival |
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https://doi.org/10.18632/oncotarget.2148
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| 4011-4025 |
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| A genomewide miRNA screen revealed miR603 as a MGMTregulating miRNA in glioblastomas |
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https://doi.org/10.18632/oncotarget.1974
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| 4026-4039 |
Clinical Research Papers
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| Whole genome expression profiling of blood cells in ovarian cancer patients Prognostic impact of the CYP1B1 MTSS1 NCALD and NOP14 genes |
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https://doi.org/10.18632/oncotarget.1938
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| 4040-4049 |
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| Week one FLTPET response predicts complete remission to RCHOP and survival in DLBCL |
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https://doi.org/10.18632/oncotarget.1990
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| 4050-4059 |
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| Potential clinical implications of BRAF mutations in histiocytic proliferations |
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https://doi.org/10.18632/oncotarget.2061
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| 4060-4070 |
Research Papers
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| Identification of aurora kinase A as an unfavorable prognostic factor and potential treatment target for metastatic gastrointestinal stromal tumors |
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https://doi.org/10.18632/oncotarget.1705
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| 4071-4086 |
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| Hemeoxygenase1 implications in cell morphology and the adhesive behavior of prostate cancer cells |
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https://doi.org/10.18632/oncotarget.1826
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| 4087-4102 |
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| Silencing of LINE1 retrotransposons contributes to variation in small noncoding RNA expression in human cancer cells |
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https://doi.org/10.18632/oncotarget.1822
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| 4103-4117 |
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| Artesunate overcomes drug resistance in multiple myeloma by inducing mitochondrial stress and noncaspase apoptosis |
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https://doi.org/10.18632/oncotarget.1847
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| 4118-4128 |
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| Metformininduced metabolic reprogramming of chemoresistant ALDHbright breast cancer cells |
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https://doi.org/10.18632/oncotarget.1864
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| 4129-4143 |
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| Loss of tumor suppressor mir203 mediates overexpression of LIM and SH3 Protein 1 LASP1 in highrisk prostate cancer thereby increasing cell proliferation and migration |
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https://doi.org/10.18632/oncotarget.1928
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| 4144-4153 |
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| Urokinase receptor promotes ovarian cancer cell dissemination through its 8495 sequence |
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https://doi.org/10.18632/oncotarget.1930
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| 4154-4169 |
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| The poison oligonucleotide F10 is highly effective against acute lymphoblastic leukemia while sparing normal hematopoietic cells |
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https://doi.org/10.18632/oncotarget.1937
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| 4170-4179 |
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| Novel combination of mitochondrial division inhibitor 1 mdivi1 and platinum agents produces synergistic proapoptotic effect in drug resistant tumor cells |
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https://doi.org/10.18632/oncotarget.1944
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| 4180-4194 |
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| Repression of liver colorectal metastasis by the serpin Spn4A a naturally occurring inhibitor of the constitutive secretory proprotein convertases |
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https://doi.org/10.18632/oncotarget.1966
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| 4195-4210 |
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| SCFβTRCP regulates osteoclastogenesis via promoting CYLD ubiquitination |
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https://doi.org/10.18632/oncotarget.1971
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| 4211-4221 |
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| PLCbeta 1 regulates the expression of miR210 during mithramycinmediated erythroid differentiation in K562 cells |
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https://doi.org/10.18632/oncotarget.1972
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| 4222-4231 |
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| Posttranslational regulation of COX2 activity by FYN in prostate cancer cells |
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https://doi.org/10.18632/oncotarget.1983
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| 4232-4243 |
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| Reduced ING1 levels in breast cancer promotes metastasis |
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https://doi.org/10.18632/oncotarget.1988
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| 4244-4256 |
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| Histone deacetylase 2 and NMyc reduce p53 protein phosphorylation at serine 46 by repressing gene transcription of tumor protein 53induced nuclear protein 1 |
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https://doi.org/10.18632/oncotarget.1991
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| 4257-4268 |
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| Identification of a ternary proteincomplex as a therapeutic target for KRasdependent colon cancer |
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https://doi.org/10.18632/oncotarget.2001
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| 4269-4282 |
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| Increased Nek1 expression in Renal Cell Carcinoma cells is associated with decreased sensitivity to DNAdamaging treatment |
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https://doi.org/10.18632/oncotarget.2005
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| 4283-4294 |
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| Relevance of IGFBP2 proteolysis in glioma and contribution of the extracellular protease ADAMTS1 |
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https://doi.org/10.18632/oncotarget.2009
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| 4295-4304 |
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| Cancer stem cells from epithelial ovarian cancer patients privilege oxidative phosphorylation and resist glucose deprivation |
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https://doi.org/10.18632/oncotarget.2010
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| 4305-4319 |
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| High nuclear level of Vav1 is a positive prognostic factor in early invasive breast tumors: a role in modulating genes related to the efficiency of metastatic process |
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https://doi.org/10.18632/oncotarget.2011
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| 4320-4336 |
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| XIAP inhibitors induce differentiation and impair clonogenic capacity of acute myeloid leukemia stem cells |
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https://doi.org/10.18632/oncotarget.2016
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| 4337-4346 |
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| Sodium dichloroacetate exhibits antileukemic activity in Bchronic lymphocytic leukemia BCLL and synergizes with the p53 activator Nutlin3 |
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https://doi.org/10.18632/oncotarget.2018
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| 4347-4360 |
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| DNA intercalator BMH21 inhibits RNA polymerase I independent of DNA damage response |
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https://doi.org/10.18632/oncotarget.2020
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| 4361-4369 |
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| SCFFBXW7α modulates the intraSphase DNAdamage checkpoint by regulating Polo like kinase1 stability |
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https://doi.org/10.18632/oncotarget.2021
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| 4370-4383 |
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| Phenotypic and genotypic characterization of azacitidinesensitive and resistant SKM1 myeloid cell lines |
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https://doi.org/10.18632/oncotarget.2024
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| 4384-4391 |
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| NOX4 promotes nonsmall cell lung cancer cell proliferation and metastasis through positive feedback regulation of PI3K/Akt signaling |
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https://doi.org/10.18632/oncotarget.2025
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| 4392-4405 |
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| Rac1 regulates skin tumors by regulation of keratin 17 through recruitment and interaction with CD11b+Gr1+ cells |
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https://doi.org/10.18632/oncotarget.2030
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| 4406-4417 |
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| Thymocyte selectionassociated high mobility group box gene TOX is aberrantly overexpressed in mycosis fungoides and correlates with poor prognosis |
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https://doi.org/10.18632/oncotarget.2031
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| 4418-4425 |
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| Apelin promotes lymphangiogenesis and lymph node metastasis |
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https://doi.org/10.18632/oncotarget.2032
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| 4426-4437 |
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| 20SGinsenoside Rg3 is a novel inhibitor of autophagy and sensitizes hepatocellular carcinoma to doxorubicin |
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https://doi.org/10.18632/oncotarget.2034
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| 4438-4451 |
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| Wildtype ALK and activating ALKR1275Q and ALKF1174L mutations upregulate Myc and initiate tumor formation in murine neural crest progenitor cells |
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https://doi.org/10.18632/oncotarget.2036
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| 4452-4466 |
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| Host defense peptides for treatment of colorectal carcinoma – a comparative in vitro and in vivo analysis |
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https://doi.org/10.18632/oncotarget.2039
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| 4467-4479 |
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| PD2/Paf1 depletion in pancreatic acinar cells promotes acinartoductal metaplasia |
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https://doi.org/10.18632/oncotarget.2041
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| 4480-4491 |
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| Mode and specificity of binding of the small molecule GANT61 to GLI determines inhibition of GLIDNA binding |
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https://doi.org/10.18632/oncotarget.2046
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| 4492-4503 |
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| New histone deacetylase inhibitors improve cisplatin antitumor properties against thoracic cancer cells |
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https://doi.org/10.18632/oncotarget.2056
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| 4504-4515 |
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| Histone deacetylase inhibitortemozolomide cotreatment inhibits melanoma growth through suppression of Chemokine CC motif ligand 2driven signals |
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https://doi.org/10.18632/oncotarget.2065
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| 4516-4528 |
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| Icotinib antagonizes ABCG2mediated multidrug resistance but not the pemetrexed resistance mediated by thymidylate synthase and ABCG2 |
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https://doi.org/10.18632/oncotarget.2102
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| 4529-4542 |
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| Discovery of novel nonATP competitive FGFR1 inhibitors and evaluation of their antitumor activity in nonsmall cell lung cancer in vitro and in vivo |
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https://doi.org/10.18632/oncotarget.2122
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| 4543-4553 |
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| Novel inhibitors are cytotoxic for myeloma cells with NFkB inducing kinasedependent activation of NFkB |
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https://doi.org/10.18632/oncotarget.2128
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| 4554-4566 |
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| Targeted cytotoxic analog of luteinizing hormonereleasing hormone LHRH AEZS108 AN152 inhibits the growth of DU145 human castrationresistant prostate cancer in vivo and in vitro through elevating p21 and ROS levels |
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https://doi.org/10.18632/oncotarget.2146
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| 4567-4578 |
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