Vol 6, No 33

Naa10 in development and disease

Vinculin-cell membrane interactions

Reducing genomic instability in iPSCs

Targeting lymphatics in inflammatory bowel disease

DNA methylation and demethylation dynamics

DCIR in the “osteo-immune” system

CCN1 in hepatobiliary injury repair

ASK “to be, or not to be?”

Targeting RIPK1,2,3 to combat inflammation

microRNAs calibrate T cell responses by regulating mTOR

TRIB3-P62 interaction, diabetes and autophagy

The quest for GAS vaccine

Targeting the SIN3A-PF1 interaction inhibits epithelial to mesenchymal transition and maintenance of a stem cell phenotype in triple negative breast cancer

Aging with ING: a comparative study of different forms of stress induced premature senescence

Gavage of D-Ribose induces Aβ-like deposits, Tau hyperphosphorylation as well as memory loss and anxiety-like behavior in mice

Suppression of FoxO6 by lipopolysaccharide in aged rat liver

Comprehensive cancer-gene panels can be used to estimate mutational load and predict clinical benefit to PD-1 blockade in clinical practice

Activin a signaling regulates cell invasion and proliferation in esophageal adenocarcinoma

JAK2 tyrosine kinase mediates integrin activation induced by CXCL12 in B-cell chronic lymphocytic leukemia

Arenobufagin intercalates with DNA leading to G₂ cell cycle arrest via ATM/ATR pathway

Detection of recurrent cytogenetic aberrations in multiple myeloma: A comparison between MLPA and iFISH

Cetuximab promotes epithelial to mesenchymal transition and cancer associated fibroblasts in patients with head and neck cancer

Comprehensive investigation of oncogenic driver mutations in Chinese non-small cell lung cancer patients

TTK activates Akt and promotes proliferation and migration of hepatocellular carcinoma cells

Phospho-ERK1/2 levels in cancer cell nuclei predict responsiveness to radiochemotherapy of rectal adenocarcinoma

Mature adipocytes in bone marrow protect myeloma cells against chemotherapy through autophagy activation

Structural basis for the indispensable role of a unique zinc finger motif in LNX2 ubiquitination

The androgen receptor controls expression of the cancer-associated sTn antigen and cell adhesion through induction of ST6GalNAc1 in prostate cancer

Variation in human cancer cell external phosphatidylserine is regulated by flippase activity and intracellular calcium

Clusterin, a gene enriched in intestinal stem cells, is required for L1-mediated colon cancer metastasis

The G-protein-coupled bile acid receptor Gpbar1 (TGR5) suppresses gastric cancer cell proliferation and migration through antagonizing STAT3 signaling pathway

The radiosensitivity index predicts for overall survival in glioblastoma

Down-regulation of miR-129-5p via the Twist1-Snail feedback loop stimulates the epithelial-mesenchymal transition and is associated with poor prognosis in breast cancer

TP53 and MDM2 single nucleotide polymorphisms influence survival in non-del(5q) myelodysplastic syndromes

MicroRNA-212 negatively regulates starvation induced autophagy in prostate cancer cells by inhibiting SIRT1 and is a modulator of angiogenesis and cellular senescence

Targeting of cytosolic phospholipase A₂α impedes cell cycle re-entry of quiescent prostate cancer cells

Characterization of adipose-derived stem cells from subcutaneous and visceral adipose tissues and their function in breast cancer cells

Cancer stem cell related markers of radioresistance in head and neck squamous cell carcinoma

RASSF8 downregulation promotes lymphangiogenesis and metastasis in esophageal squamous cell carcinoma

Characterisation of inflammatory processes in Helicobacter pylori-induced gastric lymphomagenesis in a mouse model

Cytotoxic T cell responses are enhanced by antigen design involving the presentation of MUC1 peptide on cholera toxin B subunit

LGR5 is associated with tumor aggressiveness in papillary thyroid cancer

Antitumor activity of a potent MEK inhibitor, TAK-733, against colorectal cancer cell lines and patient derived xenografts

Homozygous mdm2 SNP309 cancer cells with compromised transcriptional elongation at p53 target genes are sensitive to induction of p53-independent cell death

ILKAP, ILK and PINCH1 control cell survival of p53-wildtype glioblastoma cells after irradiation

FXR induces SOCS3 and suppresses hepatocellular carcinoma

Evaluation of a novel human IgG1 anti-claudin3 antibody that specifically recognizes its aberrantly localized antigen in ovarian cancer cells and that is suitable for selective drug delivery

Identification of thyroid tumor cell vulnerabilities through a siRNA-based functional screening

A radiosensitivity MiRNA signature validated by the TCGA database for head and neck squamous cell carcinomas

Wnt activated β-catenin and YAP proteins enhance the expression of non-coding RNA component of RNase MRP in colon cancer cells

The BET bromodomain inhibitor, JQ1, facilitates c-FLIP degradation and enhances TRAIL-induced apoptosis independent of BRD4 and c-Myc inhibition

Next generation sequencing in synovial sarcoma reveals novel gene mutations

The knockdown of H19lncRNA reveals its regulatory role in pluripotency and tumorigenesis of human embryonic carcinoma cells

The transcription factor c-Fos coordinates with histone lysine-specific demethylase 2A to activate the expression of cyclooxygenase-2

STIP is a critical nuclear scaffolding protein linking USP7 to p53-Mdm2 pathway regulation

Visualizing the antivascular effect of bortezomib on the hypoxic tumor microenvironment

A functional variant in HOXA11-AS, a novel long non-coding RNA, inhibits the oncogenic phenotype of epithelial ovarian cancer

CCL18 from tumor-associated macrophages promotes angiogenesis in breast cancer

Systemic delivery of HER2-retargeted oncolytic-HSV by mesenchymal stromal cells protects from lung and brain metastases

PAR1 participates in the ability of multidrug resistance and tumorigenesis by controlling Hippo-YAP pathway

Protein kinase CK2α catalytic subunit is overexpressed and serves as an unfavorable prognostic marker in primary hepatocellular carcinoma

Inhibition of endoplasmic reticulum chaperone protein glucose-regulated protein 78 potentiates anti-angiogenic therapy in renal cell carcinoma through inactivation of the PERK/eIF2α pathway

CD147 reinforces [Ca²⁺]_i oscillations and promotes oncogenic progression in hepatocellular carcinoma

Transient rRNA synthesis inhibition with CX-5461 is sufficient to elicit growth arrest and cell death in acute lymphoblastic leukemia cells

Targeting EMP3 suppresses proliferation and invasion of hepatocellular carcinoma cells through inactivation of PI3K/Akt pathway

A vesicular stomatitis virus glycoprotein epitope-incorporated oncolytic adenovirus overcomes CAR-dependency and shows markedly enhanced cancer cell killing and suppression of tumor growth

Targeting MCM2 function as a novel strategy for the treatment of highly malignant breast tumors

The oncolytic peptide LTX-315 induces cell death and DAMP release by mitochondria distortion in human melanoma cells

CREB1-driven expression of miR-320a promotes mitophagy by down-regulating VDAC1 expression during serum starvation in cervical cancer cells

Estradiol induces apoptosis via activation of miRNA-23a and p53: implication for gender difference in liver cancer development

Skp1 in lung cancer: clinical significance and therapeutic efficacy of its small molecule inhibitors

miR-200c inhibits breast cancer proliferation by targeting KRAS

HPV16-E2 induces prophase arrest and activates the cellular DNA damage response in vitro and in precursor lesions of cervical carcinoma

Intracellular activation of EGFR by fatty acid synthase dependent palmitoylation

Valproic acid enhances the efficacy of radiation therapy by protecting normal hippocampal neurons and sensitizing malignant glioblastoma cells

Cytokine-induced killer cells efficiently kill stem-like cancer cells of nasopharyngeal carcinoma via the NKG2D-ligands recognition

Proton pump inhibitors enhance the effects of cytotoxic agents in chemoresistant epithelial ovarian carcinoma

Multibeam inverse intensity-modulated radiotherapy (IMRT) for whole breast irradiation: a single center experience in China

Anti-α-enolase is a prognostic marker in postoperative lung cancer patients

The value of lactate dehydrogenase serum levels as a prognostic and predictive factor for advanced pancreatic cancer patients receiving sorafenib

Pre-transplant weight loss predicts inferior outcome after allogeneic stem cell transplantation in patients with myelodysplastic syndrome

S-1 plus cisplatin versus fluorouracil plus cisplatin in advanced gastric or gastro-esophageal junction adenocarcinoma patients: a pilot study

Elevated expression of Cripto-1 correlates with poor prognosis in hepatocellular carcinoma