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Deregulation of differentiation markers in PDXs after chemotherapy. See Molejon et al.

Table of Contents

Errata

Erratum: Drug resistance in multiple myeloma: latest findings and new concepts on molecular mechanisms

https://doi.org/10.18632/oncotarget.3810

Jahangir Abdi, Guoan Chen, and Hong Chang
7364
Erratum  |  PDF  |  How to cite

Reviews

Targeting AMPK for cancer prevention and treatment

https://doi.org/10.18632/oncotarget.3629

Weidong Li, Shakir M. Saud, Matthew R. Young, Guohong Chen, and Baojin Hua
7365-7378
Abstract  |  PDF  |  Full Text  |  How to cite

Priority Research Papers

Glutamate and asparagine cataplerosis underlie glutamine addiction in melanoma

https://doi.org/10.18632/oncotarget.3132

Boris Ratnikov, Pedro Aza-Blanc, Ze’ev A. Ronai, Jeffrey W. Smith, Andrei L. Osterman, and David A. Scott
7379-7389
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The SNP rs6500843 in 16p133 is associated with survival specifically among chemotherapytreated breast cancer patients

https://doi.org/10.18632/oncotarget.3506

Rainer Fagerholm, Marjanka K. Schmidt, Sofia Khan, Sajjad Rafiq, William Tapper, Kristiina Aittomäki, Dario Greco, Tuomas Heikkinen, Taru A. Muranen, Peter A. Fasching, Wolfgang Janni, Richard Weinshilboum, Christian R. Loehberg, John L. Hopper, Melissa C. Southey, Renske Keeman, Annika Lindblom, Sara Margolin, Arto Mannermaa, Vesa Kataja, Georgia Chenevix-Trench, kConFab Investigators, Diether Lambrechts, Hans Wildiers, Jenny Chang-Claude, Petra Seibold, Fergus J. Couch, Janet E. Olson, Irene L. Andrulis, Julia A. Knight, Montserrat García-Closas, Jonine Figueroa, Maartje J. Hooning, Agnes Jager, Mitul Shah, Barbara J. Perkins, Robert Luben, Ute Hamann, Maria Kabisch, Kamila Czene, Per Hall, Douglas F. Easton, Paul D.P. Pharoah, Jianjun Liu, Diana Eccles, Carl Blomqvist, and Heli Nevanlinna
7390-7407
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Deciphering the cellular source of tumor relapse identifies CD44 as a major therapeutic target in pancreatic adenocarcinoma

https://doi.org/10.18632/oncotarget.3510

Maria Inés Molejon, Juan Ignacio Tellechea, Celine Loncle, Odile Gayet, Marine Gilabert, Pauline Duconseil, Maria Belen Lopez-Millan, Vincent Moutardier, Mohamed Gasmi, Stephane Garcia, Olivier Turrini, Mehdi Ouaissi, Flora Poizat, Nelson Dusetti, and Juan Iovanna
7408-7423
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Research Papers: Gerotarget (Focus on Aging)

Modulation of TGFbeta 2 levels by lamin A in U2OS osteoblastlike cells: understanding the osteolytic process triggered by altered lamins

https://doi.org/10.18632/oncotarget.3232

Camilla Evangelisti, Pia Bernasconi, Paola Cavalcante, Cristina Cappelletti, Maria Rosaria D’Apice, Paolo Sbraccia, Giuseppe Novelli, Sabino Prencipe, Silvia Lemma, Nicola Baldini, Sofia Avnet, Stefano Squarzoni, Alberto M. Martelli, and Giovanna Lattanzi
7424-7437
Abstract  |  PDF  |  Full Text  |  How to cite

Research Papers

Dietinduced hypercholesterolemia promotes androgenindependent prostate cancer metastasis via IQGAP1 and caveolin1

https://doi.org/10.18632/oncotarget.3476

Hyeongsun Moon, Jayde E. Ruelcke, Eunju Choi, Laura J. Sharpe, Zeyad D. Nassar, Helle Bielefeldt-Ohmann, Marie-Odile Parat, Anup Shah, Mathias Francois, Kerry L. Inder, Andrew J. Brown, Pamela J. Russell, Robert G. Parton, and Michelle M. Hill
7438-7453
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MiR34a suppresses amphiregulin and tumor metastatic potential of head and neck squamous cell carcinoma HNSCC

https://doi.org/10.18632/oncotarget.3148

Jiali Zhang, Yu Wang, Xinming Chen, Yi Zhou, Fangyan Jiang, Jirong Chen, Li Wang, and Wen-Feng Zhang
7454-7469
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

YB1 and MTA1 protein levels and not DNA or mRNA alterations predict for prostate cancer recurrence

https://doi.org/10.18632/oncotarget.3477

Christine Moore Sheridan, Tristan R. Grogan, Hao G. Nguyen, Colette Galet, Matthew B. Rettig, Andrew C. Hsieh, and Davide Ruggero
7470-7480
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MUTYH mediates the toxicity of combined DNA 6thioguanine and UVA radiation

https://doi.org/10.18632/oncotarget.3037

Francesca Grasso, Vitalba Ruggieri, Gabriele De Luca, Paola Leopardi, Maria Teresa Mancuso, Ida Casorelli, Pietro Pichierri, Peter Karran, and Margherita Bignami
7481-7492
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Intratumoral diversity of telomere length in individual neuroblastoma tumors

https://doi.org/10.18632/oncotarget.2115

Annalisa Pezzolo, Angela Pistorio, Claudio Gambini, Riccardo Haupt, Manuela Ferraro, Giovanni Erminio, Bruno De Bernardi, Alberto Garaventa, and Vito Pistoia
7493-7503
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

TCGA data and patientderived orthotopic xenografts highlight pancreatic cancerassociated angiogenesis

https://doi.org/10.18632/oncotarget.3233

Jesse Gore, Kelly E. Craven, Julie L. Wilson, Gregory A. Cote, Monica Cheng, Hai V. Nguyen, Harvey M. Cramer, Stuart Sherman, and Murray Korc
7504-7521
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Nutrient/serum starvation derived TRIPBr3 downregulation accelerates apoptosis by destabilizing XIAP

https://doi.org/10.18632/oncotarget.3112

Chengping Li, Samil Jung, Soonduck Lee, Dongjun Jeong, Young Yang, Keun-Il Kim, Jong-Seok Lim, Chung-Il Cheon, Changjin Kim, Young-Sook Kang, and Myeong-Sok Lee
7522-7535
Abstract  |  PDF  |  Full Text  |  How to cite

Adrenomedullin blockade induces regression of tumor neovessels through interference with vascular endothelialcadherin signalling

https://doi.org/10.18632/oncotarget.3167

Ghizlane Khalfaoui-Bendriss, Nadège Dussault, Samantha Fernandez-Sauze, Caroline Berenguer-Daizé, Romain Sigaud, Christine Delfino, Mylène Cayol, Philippe Metellus, Olivier Chinot, Kamel Mabrouk, Pierre-Marie Martin, and L’Houcine Ouafik
7536-7553
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Antitumour effects of antibodies targeting the extracellular cysteinerich region of the receptor tyrosine kinase EphB4

https://doi.org/10.18632/oncotarget.3199

Sally-Anne Stephenson, Evelyn L. Douglas, Inga Mertens-Walker, Jessica E. Lisle, Mohanan SN Maharaj, and Adrian C. Herington
7554-7569
Abstract  |  PDF  |  Full Text  |  How to cite

Elevated Src family kinase activity stabilizes Ecadherinbased junctions and collective movement of head and neck squamous cell carcinomas

https://doi.org/10.18632/oncotarget.3071

Laurence Veracini, Dominique Grall, Sébastien Schaub, Stéphanie Beghelli-de la Forest Divonne, Marie-Christine Etienne-Grimaldi, Gérard Milano, Alexandre Bozec, Emmanuel Babin, Anne Sudaka, Juliette Thariat, and Ellen Van Obberghen-Schilling
7570-7583
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

NDRG4 a novel candidate tumor suppressor is a predictor of overall survival of colorectal cancer patients

https://doi.org/10.18632/oncotarget.3170

Dake Chu, Zixi Zhang, Yi Zhou, Yunming Li, Shaojun Zhu, Jian Zhang, Qingchuan Zhao, Gang Ji, Weizhong Wang, and Jianyong Zheng
7584-7596
Abstract  |  PDF  |  Full Text  |  How to cite

Genomic differences between pure ductal carcinoma in situ and synchronous ductal carcinoma in situ with invasive breast cancer

https://doi.org/10.18632/oncotarget.3162

Shinn Young Kim, Seung- Hyun Jung, Min Sung Kim, In-Pyo Baek, Sung Hak Lee, Tae-Min Kim, Yeun-Jun Chung, and Sug Hyung Lee
7597-7607
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

BRCA1 regulates PIG3mediated apoptosis in a p53dependent manner

https://doi.org/10.18632/oncotarget.3263

Wenwen Zhang, Jiayan Luo, Fengxia Chen, Fang Yang, Wei Song, Aiyu Zhu, and Xiaoxiang Guan
7608-7618
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Kidneytype glutaminase GLS1 is a biomarker for pathologic diagnosis and prognosis of hepatocellular carcinoma

https://doi.org/10.18632/oncotarget.3196

Decai Yu, Xianbiao Shi, Gang Meng, Jun Chen, Chen Yan, Yong Jiang, Jiwu Wei, and Yitao Ding
7619-7631
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Coculture of primary CLL cells with bone marrow mesenchymal cells CD40 ligand and CpG ODN promotes proliferation of chemoresistant CLL cells phenotypically comparable to those proliferating in vivo

https://doi.org/10.18632/oncotarget.2939

Noelia Purroy, Pau Abrisqueta, Júlia Carabia, Cecilia Carpio, Carles Palacio, Francesc Bosch, and Marta Crespo
7632-7643
Abstract  |  PDF  |  Full Text  |  How to cite

HDAC9 promotes glioblastoma growth via TAZmediated EGFR pathway activation

https://doi.org/10.18632/oncotarget.3223

Rui Yang, Yanan Wu, Mei Wang, Zhongfeng Sun, Jiahua Zou, Yundong Zhang, and Hongjuan Cui
7644-7656
Abstract  |  PDF  |  Full Text  |  How to cite

A transcriptomic signature mediated by HOXA9 promotes human glioblastoma initiation aggressiveness and resistance to temozolomide

https://doi.org/10.18632/oncotarget.3150

Marta Pojo, Céline S. Gonçalves, Ana Xavier-Magalhães, Ana Isabel Oliveira, Tiago Gonçalves, Sara Correia, Ana J. Rodrigues, Sandra Costa, Luísa Pinto, Afonso A. Pinto, José M. Lopes, Rui M. Reis, Miguel Rocha, Nuno Sousa, and Bruno M. Costa
7657-7674
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

miR145 mediates the antiproliferative and gene regulatory effects of vitamin D3 by directly targeting E2F3 in gastric cancer cells

https://doi.org/10.18632/oncotarget.3048

Su’e Chang, Ling Gao, Yang Yang, Dongdong Tong, Bo Guo, Liying Liu, Zongfang Li, Tusheng Song, and Chen Huang
7675-7685
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A dual yet opposite growthregulating function of miR204 and its target XRN1 in prostate adenocarcinoma cells and neuroendocrinelike prostate cancer cells

https://doi.org/10.18632/oncotarget.3480

Miao Ding, Biaoyang Lin, Tao Li, Yuanyuan Liu, Yuhua Li, Xiaoyu Zhou, Maohua Miao, Jinfa Gu, Hongjie Pan, Fen Yang, Tianqi Li, Xin Yuan Liu, and Runsheng Li
7686-7700
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Identifying the determinants of response to MDM2 inhibition

https://doi.org/10.18632/oncotarget.3116

Anne Y. Saiki, Sean Caenepeel, Elissa Cosgrove, Cheng Su, Michael Boedigheimer, and Jonathan D. Oliner
7701-7712
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Adiposederived stem cells promote tumor initiation and accelerate tumor growth by interleukin6 production

https://doi.org/10.18632/oncotarget.3481

Hong-Jian Wei, Rong Zeng, Jui-Hua Lu, Wen-Fu T. Lai, Wei-Hong Chen, Hen-Yu Liu, Ya-Ting Chang, and Win-Ping Deng
7713-7726
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

TP53 intron 1 hotspot rearrangements are specific to sporadic osteosarcoma and can cause LiFraumeni syndrome

https://doi.org/10.18632/oncotarget.3115

Sebastian Ribi, Daniel Baumhoer, Kristy Lee, Edison ., Audrey S.M. Teo, Babita Madan, Kang Zhang, Wendy K. Kohlmann, Fei Yao, Wah Heng Lee, Qiangze Hoi, Shaojiang Cai, Xing Yi Woo, Patrick Tan, Gernot Jundt, Jan Smida, Michaela Nathrath, Wing-Kin Sung, Joshua D. Schiffman, David M. Virshup, and Axel M. Hillmer
7727-7740
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

PTX3 gene activation in EGFinduced head and neck cancer cell metastasis

https://doi.org/10.18632/oncotarget.3482

Wei-Chiao Chang, Shuo-Lun Wu, Wan-Chen Huang, Jinn-Yuan Hsu, Shih-Hung Chan, Ju-Ming Wang, Jhih-Peng Tsai, and Ben-Kuen Chen
7741-7757
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Skeletal muscle atrophy is attenuated in tumorbearing mice under chemotherapy by treatment with fish oil and selenium

https://doi.org/10.18632/oncotarget.3483

Hang Wang, Tsung-Lin Li, Simon Hsia, I-Li Su, Yi-Lin Chan, and Chang-Jer Wu
7758-7773
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Loss of miR200c upregulates CYP1B1 and confers docetaxel resistance in renal cell carcinoma

https://doi.org/10.18632/oncotarget.3484

Inik Chang, Yozo Mitsui, Shinichiro Fukuhara, Ankurpreet Gill, Darryn K. Wong, Soichiro Yamamura, Varahram Shahryari, Z. Laura Tabatabai, Rajvir Dahiya, Dong Min Shin, and Yuichiro Tanaka
7774-7787
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Gluconeogenesis lipogenesis and HBV replication are commonly regulated by PGC1αdependent pathway

https://doi.org/10.18632/oncotarget.3050

Hong-Jhih Jhuang, Wei-Hsiang Hsu, Kuan-Ting Lin, Shih-Lan Hsu, Feng-Sheng Wang, Chen-Kung Chou, Kuen-Haur Lee, Ann-Ping Tsou, Jin-Mei Lai, Sheau-Farn Yeh, and Chi-Ying F. Huang
7788-7803
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

AP1mediated chromatin looping regulates ZEB2 transcription: new insights into TNFαinduced epithelial–mesenchymal transition in triplenegative breast cancer

https://doi.org/10.18632/oncotarget.3158

Yichun Qiao, Chiou-Nan Shiue, Jian Zhu, Ting Zhuang, Philip Jonsson, Anthony P.H. Wright, Chunyan Zhao, and Karin Dahlman-Wright
7804-7814
Abstract  |  PDF  |  Full Text  |  How to cite

Inhibition of tumor growth by a newlyidentified activator for epidermal fatty acid binding protein

https://doi.org/10.18632/oncotarget.3485

Enyu Rao, Puja Singh, Xiuhong Zhai, Yan Li, Ganqian Zhu, Yuwen Zhang, Jiaqing Hao, Young-In Chi, Rhoderick E. Brown, Margot P. Cleary, and Bing Li
7815-7827
Abstract  |  PDF  |  Full Text  |  How to cite

Knockdown of CD44 inhibits the invasion and metastasis of hepatocellular carcinoma both in vitro and in vivo by reversing epithelialmesenchymal transition

https://doi.org/10.18632/oncotarget.3488

Yuan Gao, Bai Ruan, Weihui Liu, Jianlin Wang, Xisheng Yang, Zhuochao Zhang, Xia Li, Juanli Duan, Fuqing Zhang, Rui Ding, Kaishan Tao, and Kefeng Dou
7828-7837
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Gold nanoparticles AuNPs carrying antiEBVmiRBART73p inhibit growth of EBVpositive nasopharyngeal carcinoma

https://doi.org/10.18632/oncotarget.3046

Longmei Cai, Jinbang Li, Xiaona Zhang, Yaoyong Lu, Jianguo Wang, Xiaoming Lyu, Yuxiang Chen, Jinkun Liu, Hongbing Cai, Ying Wang, and Xin Li
7838-7850
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Pleiotropic modes of action in tumor cells of RNASET2 an evolutionary highly conserved extracellular RNase

https://doi.org/10.18632/oncotarget.3490

Marta Lualdi, Edoardo Pedrini, Katia Rea, Laura Monti, Debora Scaldaferri, Marzia Gariboldi, Annalisa Camporeale, Paolo Ghia, Elena Monti, Antonella Tomassetti, Francesco Acquati, and Roberto Taramelli
7851-7865
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Downregulation of miR432 activates Wnt/βcatenin signaling and promotes human hepatocellular carcinoma proliferation

https://doi.org/10.18632/oncotarget.3492

Nan Jiang, Wen-Jie Chen, Jian-Wen Zhang, Chi Xu, Xian-Cheng Zeng, Tong Zhang, Yang Li, and Guo-Ying Wang
7866-7879
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Vasohibin1 suppresses colon cancer

https://doi.org/10.18632/oncotarget.3493

Shuai Liu, Bing Han, Qunyuan Zhang, Jie Dou, Fang Wang, Wenli Lin, Yuping Sun, and Guangyong Peng
7880-7898
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Upregulated lncRNAUCA1 contributes to progression of hepatocellular carcinoma through inhibition of miR216b and activation of FGFR1/ERK signaling pathway

https://doi.org/10.18632/oncotarget.3219

Feng Wang, Hou-Qun Ying, Bang-Shun He, Yu-Qin Pan, Qi-Wen Deng, Hui-Ling Sun, Jie Chen, Xian Liu, and Shu-Kui Wang
7899-7917
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MicroRNA200a suppresses metastatic potential of side population cells in human hepatocellular carcinoma by decreasing ZEB2

https://doi.org/10.18632/oncotarget.3486

Xisheng Yang, Jianlin Wang, Shibin Qu, Hongtao Zhang, Bai Ruan, Yuan Gao, Ben Ma, Xing Wang, Nan Wu, Xiaolei Li, Kefeng Dou, and Haimin Li
7918-7929
Abstract  |  PDF  |  Full Text  |  How to cite

MiR101 reverses the hypomethylation of the LMO3 promoter in glioma cells

https://doi.org/10.18632/oncotarget.3181

Xiaoping Liu, Qianqian Lei, Zhibin Yu, Gang Xu, Hailin Tang, Wei Wang, Zeyou Wang, Guiyuan Li, and Minghua Wu
7930-7943
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Deficiency of AMPK in CD8+ T cells suppresses their antitumor function by inducing protein phosphatasemediated cell death

https://doi.org/10.18632/oncotarget.3501

Enyu Rao, Yuwen Zhang, Ganqian Zhu, Jiaqing Hao, Xuan-Mai T. Persson, Nejat K. Egilmez, Jill Suttles, and Bing Li
7944-7958
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Extracellular vesicles derived from renal cancer stem cells induce a protumorigenic phenotype in mesenchymal stromal cells

https://doi.org/10.18632/oncotarget.3503

Rafael Soares Lindoso, Federica Collino, and Giovanni Camussi
7959-7969
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tetraspanin CD9 determines invasiveness and tumorigenicity of human breast cancer cells

https://doi.org/10.18632/oncotarget.3419

Germana Rappa, Toni M. Green, Jana Karbanová, Denis Corbeil, and Aurelio Lorico
7970-7991
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Tetrandrine induces autophagy and differentiation by activating ROS and Notch1 signaling in leukemia cells

https://doi.org/10.18632/oncotarget.3505

Ting Liu, Qiuxu Men, Guixian Wu, Chunrong Yu, Zan Huang, Xin Liu, and Wenhua Li
7992-8006
Abstract  |  PDF  |  Full Text  |  How to cite

UV irradiation/cold shockmediated apoptosis is switched to bubbling cell death at low temperatures

https://doi.org/10.18632/oncotarget.3153

Szu-Jung Chen, Pei-Wen Lin, Hsin-Ping Lin, Sheng-Shyang Huang, Feng-Jie Lai, Hamm-Ming Sheu, Li-Jin Hsu, and Nan-Shan Chang
8007-8018
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Computational prediction and experimental validation of a novel synthesized panPIM inhibitor PI003 and its apoptosisinducing mechanisms in cervical cancer

https://doi.org/10.18632/oncotarget.3139

Zhongyu Liu, Weihua He, Jianglin Gao, Junhua Luo, Xian Huang, and Chunfang Gao
8019-8035
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

The oncogenic role of JC virus T antigen in lens tumors without cell specificity of alternative splicing of its intron

https://doi.org/10.18632/oncotarget.3507

Wen-feng Gou, Shuang Zhao, Dao-fu Shen, Xue-feng Yang, Yun-peng Liu, Hong-zhi Sun, Jun-sheng Luo, and Hua-chuan Zheng
8036-8045
Abstract  |  PDF  |  Full Text  |  How to cite

Ku80 cooperates with CBP to promote COX2 expression and tumor growth

https://doi.org/10.18632/oncotarget.3508

Yao Xiao, Jingshu Wang, Yu Qin, Yang Xuan, Yunlu Jia, Wenxian Hu, Wendan Yu, Meng Dai, Zhenglin Li, Canhui Yi, Shilei Zhao, Mei Li, Sha Du, Wei Cheng, Xiangsheng Xiao, Yiming Chen, Taihua Wu, Songshu Meng, Yuhui Yuan, Quentin Liu, Wenlin Huang, Wei Guo, Shusen Wang, and Wuguo Deng
8046-8061
Abstract  |  PDF  |  Full Text  |  How to cite

Dual targeting of acute myeloid leukemia progenitors by catalytic mTOR inhibition and blockade of the p110α subunit of PI3 kinase

https://doi.org/10.18632/oncotarget.3509

Marco Colamonici, Gavin Blyth, Diana Saleiro, Amy Szilard, Meghan Bliss-Moreau, Francis J. Giles, Jessica K. Altman, Elspeth M. Beauchamp, and Leonidas C. Platanias
8062-8070
Abstract  |  PDF  |  Full Text  |  How to cite

Systems biology networkbased discovery of a small molecule activator BLAD008 targeting AMPK/ZIPK and inducing apoptosis in cervical cancer

https://doi.org/10.18632/oncotarget.3513

Leilei Fu, Shouyue Zhang, Lan Zhang, Xupeng Tong, Jin Zhang, Yonghui Zhang, Liang Ouyang, Bo Liu, and Jian Huang
8071-8088
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MicroRNA31 functions as a tumor suppressor by regulating cell cycle and epithelialmesenchymal transition regulatory proteins in liver cancer

https://doi.org/10.18632/oncotarget.3512

Hyung Seok Kim, Kyo Sun Lee, Hyun Jin Bae, Jung Woo Eun, Qingyu Shen, Se Jin Park, Woo Chan Shin, Hee Doo Yang, Mijung Park, Won Sang Park, Yong-Koo Kang, and Suk Woo Nam
8089-8102
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Secreted uPAR isoform 2 uPAR7b is a novel direct target of miR221

https://doi.org/10.18632/oncotarget.3516

Natalie Falkenberg, Nataša Anastasov, Annalisa Schaub, Vanja Radulovic, Manfred Schmitt, Viktor Magdolen, and Michaela Aubele
8103-8114
Abstract  |  PDF  |  Full Text  |  How to cite

Oncogenic mutations of thyroid hormone receptor β

https://doi.org/10.18632/oncotarget.3466

Jeong Won Park, Li Zhao, Mark Willingham, and Sheue-yann Cheng
8115-8131
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Silencing of voltagegated potassium channel KV93 inhibits proliferation in human colon and lung carcinoma cells

https://doi.org/10.18632/oncotarget.3517

Jeong-Ha Lee, Jun-Won Park, Jun Kyu Byun, Hark Kyun Kim, Pan Dong Ryu, So Yeong Lee, and Dae-Yong Kim
8132-8143
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Mitogenactivated protein kinase binding protein 1 MAPKBP1 is an unfavorable prognostic biomarker in cytogenetically normal acute myeloid leukemia

https://doi.org/10.18632/oncotarget.3519

Lin Fu, Jinlong Shi, Kai Hu, Jijun Wang, Weidong Wang, and Xiaoyan Ke
8144-8154
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Low dose radiation induced senescence of human mesenchymal stromal cells and impaired the autophagy process

https://doi.org/10.18632/oncotarget.2692

Nicola Alessio, Stefania Del Gaudio, Stefania Capasso, Giovanni Di Bernardo, Salvatore Cappabianca, Marilena Cipollaro, Gianfranco Peluso, and Umberto Galderisi
8155-8166
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Activation of NRF2 by p62 and proteasome reduction in sphereforming breast carcinoma cells

https://doi.org/10.18632/oncotarget.3047

In-geun Ryoo, Bo-hyun Choi, and Mi-Kyoung Kwak
8167-8184
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

FOXM1: A novel drug target in gastroenteropancreatic neuroendocrine tumors

https://doi.org/10.18632/oncotarget.3600

Franziska Briest, Erika Berg, Irina Grass, Helma Freitag, Daniel Kaemmerer, Florentine Lewens, Friederike Christen, Ruza Arsenic, Annelore Altendorf-Hofmann, Almut Kunze, Jörg Sänger, Thomas Knösel, Britta Siegmund, Michael Hummel, and Patricia Grabowski
8185-8199
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Marine compounds inhibit growth of multiple myeloma in vitro and in vivo

https://doi.org/10.18632/oncotarget.3362

Normann Steiner, Domenico Ribatti, Wolfgang Willenbacher, Karin Jöhrer, Johann Kern, Christian Marinaccio, Miguel Aracil, Luis F. García-Fernández, Guenther Gastl, Gerold Untergasser, and Eberhard Gunsilius
8200-8209
Abstract  |  PDF  |  Full Text  |  How to cite

Ndrg2 promoter hypermethylation triggered by helicobacter pylori infection correlates with poor patients survival in human gastric carcinoma

https://doi.org/10.18632/oncotarget.3601

Zhi-Qiang Ling, Ming-Hua Ge, Xiao-Xiao Lu, Jin Han, Yi-Chen Wu, Xiang Liu, Xin Zhu, and Lian-Lian Hong
8210-8225
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

MDM2 turnover and expression of ATRX determine the choice between quiescence and senescence in response to CDK4 inhibition

https://doi.org/10.18632/oncotarget.3364

Marta Kovatcheva, David D. Liu, Mark A. Dickson, Mary E. Klein, Rachael O’Connor, Fatima O. Wilder, Nicholas D. Socci, William D. Tap, Gary K. Schwartz, Samuel Singer, Aimee M. Crago, and Andrew Koff
8226-8243
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

NFκBmediated miR124 suppresses metastasis of nonsmallcell lung cancer by targeting MYO10

https://doi.org/10.18632/oncotarget.3135

Yingjia Sun, Xinghao Ai, Shengping Shen, and Shun Lu
8244-8254
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Prognostic factors of survival in patients treated with nabpaclitaxel plus gemcitabine regimen for advanced or metastatic pancreatic cancer: A single institutional experience

https://doi.org/10.18632/oncotarget.3143

Giovanni Lo Re, Davide A Santeufemia, Luisa Foltran, Ettore Bidoli, Stefano M.M. Basso, and Franco Lumachi
8255-8260
Abstract  |  PDF  |  Full Text  |  How to cite

Peripheral myeloidderived suppressor and T regulatory PD1 positive cells predict response to neoadjuvant shortcourse radiotherapy in rectal cancer patients

https://doi.org/10.18632/oncotarget.3014

Maria Napolitano, Crescenzo D'Alterio, Eleonora Cardone, Anna Maria Trotta, Biagio Pecori, Daniela Rega, Ugo Pace, Dario Scala, Giosuè Scognamiglio, Fabiana Tatangelo, Carmela Cacciapuoti, Roberto Pacelli, Paolo Delrio, and Stefania Scala
8261-8270
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

A novel HIF1αintegrinlinked kinase regulatory loop that facilitates hypoxiainduced HIF1α expression and epithelialmesenchymal transition in cancer cells

https://doi.org/10.18632/oncotarget.3186

Chih-Chien Chou, Hsaio-Ching Chuang, Santosh B. Salunke, Samuel K. Kulp, and Ching-Shih Chen
8271-8285
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

miR93 promotes cell proliferation in gliomas through activation of PI3K/Akt signaling pathway

https://doi.org/10.18632/oncotarget.3221

Lili Jiang, Chanjuan Wang, Fangyong Lei, Longjuan Zhang, Xin Zhang, Aibin Liu, Geyan Wu, Jinrong Zhu, and Libing Song
8286-8299
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Low molecular weight protein tyrosine phosphatase LMWPTP upregulation mediates malignant potential in colorectal cancer

https://doi.org/10.18632/oncotarget.3224

Elmer Hoekstra, Liudmila L. Kodach, Asha M. Das, Roberta R. Ruela-de-Sousa, Carmen V. Ferreira, James C. Hardwick, C. Janneke van der Woude, Maikel P. Peppelenbosch, Timo L.M. ten Hagen, and Gwenny M. Fuhler
8300-8312
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

CD133 initiates tumors induces epithelialmesenchymal transition and increases metastasis in pancreatic cancer

https://doi.org/10.18632/oncotarget.3228

Alice Nomura, Sulagna Banerjee, Rohit Chugh, Vikas Dudeja, Masato Yamamoto, Selwyn M. Vickers, and Ashok K. Saluja
8313-8322
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Zipperinteracting protein kinase promotes epithelialmesenchymal transition invasion and metastasis through AKT and NFkB signaling and is associated with metastasis and poor prognosis in gastric cancer patients

https://doi.org/10.18632/oncotarget.3200

Jian Li, Zhijuan Deng, Zhu Wang, Dong Wang, Longjuan Zhang, Qiao Su, Yingrong Lai, Bin Li, Zexing Luo, Xu Chen, Yu Chen, Xiaohui Huang, Jieyi Ma, Wenjian Wang, Wen Li, Jiong Bi, and Xinyuan Guan
8323-8338
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Decreased miR122 in hepatocellular carcinoma leads to chemoresistance with increased arginine

https://doi.org/10.18632/oncotarget.3234

Takahiro Kishikawa, Motoyuki Otsuka, Tan Poh Seng, Motoko Ohno, Xiaochen Sun, Takeshi Yoshikawa, Chikako Shibata, Akemi Takata, Kentaro Kojima, Kenji Takehana, Maki Ohishi, Sana Ota, Tomoyuki Noyama, Yuji Kondo, Masaya Sato, Tomoyoshi Soga, Yujin Hoshida, and Kazuhiko Koike
8339-8352
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

HOTAIR is a therapeutic target in glioblastoma

https://doi.org/10.18632/oncotarget.3229

Xuan Zhou, Yu Ren, Jing Zhang, Chuanbao Zhang, Kailiang Zhang, Lei Han, Lingping Kong, Jianwei Wei, Luyue Chen, Jingxuan Yang, Qixue Wang, Jianning Zhang, Yuqi Yang, Tao Jiang, Min Li, and Chunsheng Kang
8353-8365
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Clinical Research Papers

Bloodbrain barrier permeability of gefitinib in patients with brain metastases from nonsmallcell lung cancer before and during whole brain radiation therapy

https://doi.org/10.18632/oncotarget.3187

Yin-duo Zeng, Hai Liao, Tao Qin, Li Zhang, Wei-dong Wei, Jian-zhong Liang, Fei Xu, Xiao-xiao Dinglin, Shu-xiang Ma, and Li-kun Chen
8366-8376
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Overexpression of thymidylate synthase TYMS is associated with aggressive tumor features and early PSA recurrence in prostate cancer

https://doi.org/10.18632/oncotarget.3107

Christoph Burdelski, Christian Strauss, Maria Christina Tsourlakis, Martina Kluth, Claudia Hube-Magg, Nathaniel Melling, Patrick Lebok, Sarah Minner, Christina Koop, Markus Graefen, Hans Heinzer, Corinna Wittmer, Till Krech, Guido Sauter, Waldemar Wilczak, Ronald Simon, Thorsten Schlomm, and Stefan Steurer
8377-8387
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Role of ASXL1 and TP53 mutations in the molecular classification and prognosis of acute myeloid leukemias with myelodysplasiarelated changes

https://doi.org/10.18632/oncotarget.3460

Raynier Devillier, Véronique Mansat-De Mas, Veronique Gelsi-Boyer, Cecile Demur, Anne Murati, Jill Corre, Thomas Prebet, Sarah Bertoli, Mandy Brecqueville, Christine Arnoulet, Christian Recher, Norbert Vey, Marie-Joelle Mozziconacci, Eric Delabesse, and Daniel Birnbaum
8388-8396
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

Synchronous occurrence of gastrointestinal stromal tumors and other digestive tract malignancies in the elderly

https://doi.org/10.18632/oncotarget.3108

Chaoyong Shen, Haining Chen, Yuan Yin, Jiaju Chen, Luyin Han, Bo Zhang, Zhixin Chen, and Jiaping Chen
8397-8406
Abstract  |  PDF  |  Full Text  |  How to cite

MLH1 V384D polymorphism associates with poor response to EGFR tyrosine kinase inhibitors in patients with EGFR L858Rpositive lung adenocarcinoma

https://doi.org/10.18632/oncotarget.3511

Chao-Hua Chiu, Hsiang-Ling Ho, Howard Doong, Yi-Chen Yeh, Mei-Yu Chen, Teh-Ying Chou, and Chun-Ming Tsai
8407-8417
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite

11CMethioninePET: A novel and sensitive tool for monitoring of early response to treatment in multiple myeloma

https://doi.org/10.18632/oncotarget.3053

Katharina Lückerath, Constantin Lapa, Christa Albert, Ken Herrmann, Gerhard Jörg, Samuel Samnick, Herrmann Einsele, Stefan Knop, and Andreas K. Buck
8418-8429
Abstract  |  PDF  |  Full Text  |  Supplementary Information  |  How to cite


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