Vol 6, No 10

The SNP rs6500843 in 16p13.3 is associated with survival specifically among chemotherapy-treated breast cancer patients

Deciphering the cellular source of tumor relapse identifies CD44 as a major therapeutic target in pancreatic adenocarcinoma

MiR-34a suppresses amphiregulin and tumor metastatic potential of head and neck squamous cell carcinoma (HNSCC)

YB-1 and MTA1 protein levels and not DNA or mRNA alterations predict for prostate cancer recurrence

MUTYH mediates the toxicity of combined DNA 6-thioguanine and UVA radiation

Intratumoral diversity of telomere length in individual neuroblastoma tumors

TCGA data and patient-derived orthotopic xenografts highlight pancreatic cancer-associated angiogenesis

Nutrient/serum starvation derived TRIP-Br3 down-regulation accelerates apoptosis by destabilizing XIAP

Adrenomedullin blockade induces regression of tumor neovessels through interference with vascular endothelial-cadherin signalling

Anti-tumour effects of antibodies targeting the extracellular cysteine-rich region of the receptor tyrosine kinase EphB4

Elevated Src family kinase activity stabilizes E-cadherin-based junctions and collective movement of head and neck squamous cell carcinomas

NDRG4, a novel candidate tumor suppressor, is a predictor of overall survival of colorectal cancer patients

Genomic differences between pure ductal carcinoma in situ and synchronous ductal carcinoma in situ with invasive breast cancer

BRCA1 regulates PIG3-mediated apoptosis in a p53-dependent manner

Kidney-type glutaminase (GLS1) is a biomarker for pathologic diagnosis and prognosis of hepatocellular carcinoma

Co-culture of primary CLL cells with bone marrow mesenchymal cells, CD40 ligand and CpG ODN promotes proliferation of chemoresistant CLL cells phenotypically comparable to those proliferating in vivo

HDAC9 promotes glioblastoma growth via TAZ-mediated EGFR pathway activation

A transcriptomic signature mediated by HOXA9 promotes human glioblastoma initiation, aggressiveness and resistance to temozolomide

miR-145 mediates the antiproliferative and gene regulatory effects of vitamin D3 by directly targeting E2F3 in gastric cancer cells

A dual yet opposite growth-regulating function of miR-204 and its target XRN1 in prostate adenocarcinoma cells and neuroendocrine-like prostate cancer cells

Identifying the determinants of response to MDM2 inhibition

Adipose-derived stem cells promote tumor initiation and accelerate tumor growth by interleukin-6 production

TP53 intron 1 hotspot rearrangements are specific to sporadic osteosarcoma and can cause Li-Fraumeni syndrome

PTX3 gene activation in EGF-induced head and neck cancer cell metastasis

Skeletal muscle atrophy is attenuated in tumor-bearing mice under chemotherapy by treatment with fish oil and selenium

Loss of miR-200c up-regulates CYP1B1 and confers docetaxel resistance in renal cell carcinoma

Gluconeogenesis, lipogenesis, and HBV replication are commonly regulated by PGC-1α-dependent pathway

AP-1-mediated chromatin looping regulates ZEB2 transcription: new insights into TNFα-induced epithelial–mesenchymal transition in triple-negative breast cancer

Inhibition of tumor growth by a newly-identified activator for epidermal fatty acid binding protein

Knockdown of CD44 inhibits the invasion and metastasis of hepatocellular carcinoma both in vitro and in vivo by reversing epithelial-mesenchymal transition

Gold nano-particles (AuNPs) carrying anti-EBV-miR-BART7-3p inhibit growth of EBV-positive nasopharyngeal carcinoma

Pleiotropic modes of action in tumor cells of RNASET2, an evolutionary highly conserved extracellular RNase

Downregulation of miR-432 activates Wnt/β-catenin signaling and promotes human hepatocellular carcinoma proliferation

Vasohibin-1 suppresses colon cancer

Upregulated lncRNA-UCA1 contributes to progression of hepatocellular carcinoma through inhibition of miR-216b and activation of FGFR1/ERK signaling pathway

MicroRNA-200a suppresses metastatic potential of side population cells in human hepatocellular carcinoma by decreasing ZEB2

MiR-101 reverses the hypomethylation of the LMO3 promoter in glioma cells

Deficiency of AMPK in CD8⁺ T cells suppresses their anti-tumor function by inducing protein phosphatase-mediated cell death

Extracellular vesicles derived from renal cancer stem cells induce a pro-tumorigenic phenotype in mesenchymal stromal cells

Tetraspanin CD9 determines invasiveness and tumorigenicity of human breast cancer cells

Tetrandrine induces autophagy and differentiation by activating ROS and Notch1 signaling in leukemia cells

UV irradiation/cold shock-mediated apoptosis is switched to bubbling cell death at low temperatures

Computational prediction and experimental validation of a novel synthesized pan-PIM inhibitor PI003 and its apoptosis-inducing mechanisms in cervical cancer

The oncogenic role of JC virus T antigen in lens tumors without cell specificity of alternative splicing of its intron

Ku80 cooperates with CBP to promote COX-2 expression and tumor growth

Dual targeting of acute myeloid leukemia progenitors by catalytic mTOR inhibition and blockade of the p110α subunit of PI3 kinase

Systems biology network-based discovery of a small molecule activator BL-AD008 targeting AMPK/ZIPK and inducing apoptosis in cervical cancer

MicroRNA-31 functions as a tumor suppressor by regulating cell cycle and epithelial-mesenchymal transition regulatory proteins in liver cancer

Secreted uPAR isoform 2 (uPAR7b) is a novel direct target of miR-221

Oncogenic mutations of thyroid hormone receptor β

Silencing of voltage-gated potassium channel K_V9.3 inhibits proliferation in human colon and lung carcinoma cells

Mitogen-activated protein kinase binding protein 1 (MAPKBP1) is an unfavorable prognostic biomarker in cytogenetically normal acute myeloid leukemia

Low dose radiation induced senescence of human mesenchymal stromal cells and impaired the autophagy process

Activation of NRF2 by p62 and proteasome reduction in sphere-forming breast carcinoma cells

FOXM1: A novel drug target in gastroenteropancreatic neuroendocrine tumors

Marine compounds inhibit growth of multiple myeloma in vitro and in vivo

Ndrg2 promoter hypermethylation triggered by helicobacter pylori infection correlates with poor patients survival in human gastric carcinoma

MDM2 turnover and expression of ATRX determine the choice between quiescence and senescence in response to CDK4 inhibition

NF-κB-mediated miR-124 suppresses metastasis of non-small-cell lung cancer by targeting MYO10

Prognostic factors of survival in patients treated with nab-paclitaxel plus gemcitabine regimen for advanced or metastatic pancreatic cancer: A single institutional experience

Peripheral myeloid-derived suppressor and T regulatory PD-1 positive cells predict response to neoadjuvant short-course radiotherapy in rectal cancer patients

A novel HIF-1α-integrin-linked kinase regulatory loop that facilitates hypoxia-induced HIF-1α expression and epithelial-mesenchymal transition in cancer cells

miR-93 promotes cell proliferation in gliomas through activation of PI3K/Akt signaling pathway

Low molecular weight protein tyrosine phosphatase (LMWPTP) upregulation mediates malignant potential in colorectal cancer

CD133 initiates tumors, induces epithelial-mesenchymal transition and increases metastasis in pancreatic cancer

Zipper-interacting protein kinase promotes epithelial-mesenchymal transition, invasion and metastasis through AKT and NF-kB signaling and is associated with metastasis and poor prognosis in gastric cancer patients

Decreased miR122 in hepatocellular carcinoma leads to chemoresistance with increased arginine

HOTAIR is a therapeutic target in glioblastoma

Overexpression of thymidylate synthase (TYMS) is associated with aggressive tumor features and early PSA recurrence in prostate cancer

Role of ASXL1 and TP53 mutations in the molecular classification and prognosis of acute myeloid leukemias with myelodysplasia-related changes

Synchronous occurrence of gastrointestinal stromal tumors and other digestive tract malignancies in the elderly

MLH1 V384D polymorphism associates with poor response to EGFR tyrosine kinase inhibitors in patients with EGFR L858R-positive lung adenocarcinoma

¹¹C-Methionine-PET: A novel and sensitive tool for monitoring of early response to treatment in multiple myeloma