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SHP2 silencing prevents splenomegaly in a mouse model of SM. Representative images of spleens isolated from DBA/2 mice at day 13 following retro-orbital injection of saline (sham), or P815-NT cells, or P815-KD cells. See Sharma et al.
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Table of Contents
Editorial News
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| Spy'ing on differentiation in neuroblastoma |
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https://doi.org/10.18632/oncotarget.2325
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| 5848-5849 |
Editorial
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| NSCLC metastasis: going with ELMO3 |
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https://doi.org/10.18632/oncotarget.2341
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| 5850-5851 |
Reviews
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| Cannabinoids as therapeutic agents in cancer: current status and future implications |
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https://doi.org/10.18632/oncotarget.2233
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| 5852-5872 |
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| The NF1 gene revisited – from bench to bedside |
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https://doi.org/10.18632/oncotarget.2194
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| 5873-5892 |
Research Papers
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| Eradication of metastatic melanoma through cooperative expression of RNAbased HDAC1 inhibitor and p73 by oncolytic adenovirus |
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https://doi.org/10.18632/oncotarget.1839
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| 5893-5907 |
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| FGFR1 activation is an escape mechanism in human lung cancer cells resistant to afatinib a panEGFR family kinase inhibitor |
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https://doi.org/10.18632/oncotarget.1866
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| 5908-5919 |
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| SPHK1 regulates proliferation and survival responses in triplenegative breast cancer |
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https://doi.org/10.18632/oncotarget.1874
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| 5920-5933 |
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| Nuclear HER4 mediates acquired resistance to trastuzumab and is associated with poor outcome in HER2 positive breast cancer |
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https://doi.org/10.18632/oncotarget.1904
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| 5934-5949 |
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| Antineoplastic properties of hydralazine in prostate cancer |
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https://doi.org/10.18632/oncotarget.1909
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| 5950-5964 |
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| Identification of a gene expression driven progression pathway in myxoid liposarcoma |
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https://doi.org/10.18632/oncotarget.2023
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| 5965-5977 |
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| A novel copperI complex induces ERstressmediated apoptosis and sensitizes Bacute lymphoblastic leukemia cells to chemotherapeutic agents |
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https://doi.org/10.18632/oncotarget.2027
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| 5978-5991 |
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| The stress phenotype makes cancer cells addicted to CDT2 a substrate receptor of the CRL4 ubiquitin ligase |
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https://doi.org/10.18632/oncotarget.2042
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| 5992-6002 |
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| Somatic intronic microsatellite loci differentiate glioblastoma from lowergrade gliomas |
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https://doi.org/10.18632/oncotarget.2076
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| 6003-6014 |
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| Loss of 4EBP1 function induces EMT and promotes cancer cell migration and invasion via capdependent translational activation of snail |
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https://doi.org/10.18632/oncotarget.2109
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| 6015-6027 |
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| 4EGI1 targets breast cancer stem cells by selective inhibition of translation that persists in CSC maintenance proliferation and metastasis |
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https://doi.org/10.18632/oncotarget.2112
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| 6028-6037 |
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| PTK6/BRK is expressed in the normal mammary gland and activated at the plasma membrane in breast tumors |
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https://doi.org/10.18632/oncotarget.2153
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| 6038-6048 |
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| MicroRNA101 targets EZH2 MCL1 and FOS to suppress proliferation invasion and stem celllike phenotype of aggressive endometrial cancer cells |
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https://doi.org/10.18632/oncotarget.2157
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| 6049-6062 |
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| Dietary energy balance modulates ovarian cancer progression and metastasis |
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https://doi.org/10.18632/oncotarget.2168
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| 6063-6075 |
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| Antiapoptotic Effects of PCP4/PEP19 in Human Breast Cancer Cell Lines: A Novel Oncotarget |
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https://doi.org/10.18632/oncotarget.2161
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| 6076-6086 |
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| Discovery of selective inhibitors of Glutaminase2 which inhibit mTORC1 activate autophagy and inhibit proliferation in cancer cells |
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https://doi.org/10.18632/oncotarget.2173
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| 6087-6101 |
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| Selective inhibitors of nuclear export SINE as novel therapeutics for prostate cancer |
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https://doi.org/10.18632/oncotarget.2174
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| 6102-6112 |
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| Acquisition of radioresistance in docetaxelresistant human lung adenocarcinoma cells is linked with dysregulation of miR451/cMycsurvivin/rad51 signaling |
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https://doi.org/10.18632/oncotarget.2176
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| 6113-6129 |
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| Oncogenic KITinduced aggressive systemic mastocytosis requires SHP2/PTPN11 phosphatase for disease progression in mice |
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https://doi.org/10.18632/oncotarget.2177
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| 6130-6141 |
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| AKT regulates NPM dependent ARF localization and p53mut stability in tumors |
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https://doi.org/10.18632/oncotarget.2178
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| 6142-6167 |
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| Top associated SNPs in prostate cancer are significantly enriched in cisexpression quantitative trait loci and at transcription factor binding sites |
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https://doi.org/10.18632/oncotarget.2179
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| 6168-6177 |
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| Fbox protein FBXO31 is downregulated in gastric cancer and negatively regulated by miR17 and miR20a |
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https://doi.org/10.18632/oncotarget.2183
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| 6178-6190 |
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| CD157 enhances malignant pleural mesothelioma aggressiveness and predicts poor clinical outcome |
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https://doi.org/10.18632/oncotarget.2186
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| 6191-6205 |
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| Microsatellite instability and ploidy status define three categories with distinctive prognostic impact in endometrioid endometrial cancer |
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https://doi.org/10.18632/oncotarget.2187
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| 6206-6217 |
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| MicroRNA100 promotes the autophagy of hepatocellular carcinoma cells by inhibiting the expression of mTOR and IGF1R |
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https://doi.org/10.18632/oncotarget.2189
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| 6218-6228 |
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| The AuroraA inhibitor MLN8237 affects multiple mitotic processes and induces dosedependent mitotic abnormalities and aneuploidy |
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https://doi.org/10.18632/oncotarget.2190
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| 6229-6242 |
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| SHP1 is a target of regorafenib in colorectal cancer |
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https://doi.org/10.18632/oncotarget.2191
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| 6243-6251 |
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| The small heat shock protein B8 HSPB8 confers resistance to bortezomib by promoting autophagic removal of misfolded proteins in multiple myeloma cells |
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https://doi.org/10.18632/oncotarget.2193
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| 6252-6266 |
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| Surgeryinduced wound response promotes stemlike and tumorinitiating features of breast cancer cells via STAT3 signaling |
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https://doi.org/10.18632/oncotarget.2195
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| 6267-6279 |
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| MRD assessed by WT1 and NPM1 transcript levels identifies distinct outcomes in AML patients and is influenced by gemtuzumab ozogamicin |
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https://doi.org/10.18632/oncotarget.2196
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| 6280-6288 |
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| Loss of PTEN stabilizes the lipid modifying enzyme cytosolic phospholipase A2α via AKT in prostate cancer cells |
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https://doi.org/10.18632/oncotarget.2198
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| 6289-6299 |
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| Cdc6 cooperates with cMyc to promote genome instability and epithelial to mesenchymal transition EMT in zebrafish |
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https://doi.org/10.18632/oncotarget.2204
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| 6300-6311 |
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| Thyroid hormone regulates adhesion migration and matrix metalloproteinase 9 activity via αvβ3 integrin in myeloma cells |
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https://doi.org/10.18632/oncotarget.2205
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| 6312-6322 |
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| Chronic treatment with cisplatin induces replicationdependent sister chromatid recombination to confer cisplatinresistant phenotype in nasopharyngeal carcinoma |
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https://doi.org/10.18632/oncotarget.2210
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| 6323-6337 |
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| Impact of human MLL/COMPASS and polycomb complexes on the DNA methylome |
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https://doi.org/10.18632/oncotarget.2215
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| 6338-6352 |
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| Hypoxia suppresses cylindromatosis CYLD expression to promote inflammation in glioblastoma: possible link to acquired resistance to antiVEGF therapy |
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https://doi.org/10.18632/oncotarget.2216
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| 6353-6364 |
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| Mitophagy promotes replication of oncolytic Newcastle disease virus by blocking intrinsic apoptosis in lung cancer cells |
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https://doi.org/10.18632/oncotarget.2219
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| 6365-6374 |
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| MicroRNA99a and 100 mediated upregulation of FOXA1 in bladder cancer |
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https://doi.org/10.18632/oncotarget.2221
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| 6375-6386 |
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| Overexpression of HMGB1 in melanoma predicts patient survival and suppression of HMGB1 induces cell cycle arrest and senescence in association with p21 Waf1/Cip1 upregulation via a p53independent Sp1dependent pathway |
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https://doi.org/10.18632/oncotarget.2201
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| 6387-6403 |
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| Targeted ultradeep sequencing reveals recurrent and mutually exclusive mutations of cancer genes in blastic plasmacytoid dendritic cell neoplasm |
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https://doi.org/10.18632/oncotarget.2223
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| 6404-6413 |
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| FANCD2 reexpression is associated with glioma grade and chemical inhibition of the Fanconi Anaemia pathway sensitises gliomas to chemotherapeutic agents |
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https://doi.org/10.18632/oncotarget.2225
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| 6414-6424 |
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| The role of homeostatic regulation between tumor suppressor DAB2IP and oncogenic Skp2 in prostate cancer growth |
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https://doi.org/10.18632/oncotarget.2228
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| 6425-6436 |
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| A 5gene classifier from the carcinomaassociated fibroblast transcriptomic profile and clinical outcome in colorectal cancer |
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https://doi.org/10.18632/oncotarget.2237
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| 6437-6452 |
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| Sensitization of ovarian cancer cells to cisplatin by gold nanoparticles |
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https://doi.org/10.18632/oncotarget.2203
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| 6453-6465 |
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| T cellrecruiting triplebody 19319 mediates serial lysis of malignant Blymphoid cells by a single T cell |
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https://doi.org/10.18632/oncotarget.2238
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| 6466-6483 |
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| Therapeutic CK2 inhibition attenuates diverse prosurvival signaling cascades and decreases cell viability in human breast cancer cells |
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https://doi.org/10.18632/oncotarget.2248
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| 6484-6496 |
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| Multifunctional targeting daunorubicin plus quinacrine liposomes modified by wheat germ agglutinin and tamoxifen for treating brain glioma and glioma stem cells |
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https://doi.org/10.18632/oncotarget.2267
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| 6497-6511 |
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| CDK4/6 inhibitors have potent activity in combination with pathway selective therapeutic agents in models of pancreatic cancer |
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https://doi.org/10.18632/oncotarget.2270
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| 6512-6525 |
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| Treatment of osteosarcoma with microwave thermal ablation to induce immunogenic cell death |
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https://doi.org/10.18632/oncotarget.2310
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| 6526-6539 |
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| The antitumor activator sMEK1 and paclitaxel additively decrease expression of HIF1α and VEGF via mTORC1S6K/4EBPdependent signaling pathways |
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https://doi.org/10.18632/oncotarget.2119
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| 6540-6551 |
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