The Oncosearch | Oncotarget

Randomized, double-blind trial of F14512, a polyamine-vectorized anticancer drug, compared with etoposide phosphate, in dogs with naturally occurring lymphoma Research Paper

Pierre Boyé, Franck Floch, François Serres, Zacharie Segaoula, Juliette Hordeaux, Quentin Pascal, Virginie Coste, Sandy Courapied, Emmanuel Bouchaert, Agata Rybicka, Claire Mazuy, Laurent Marescaux, Kévyn Geeraert, Corinne Fournel-Fleury, Alain Duhamel, François Machuron, Pierre Ferré, Aurélie Pétain, Nicolas Guilbaud, Dominique Tierny, Bruno Gomes

Published Feb 18, 2020 · Vol. 11, No. 7 · pp. 671-686

Keywords: etoposide phosphate, F14512, non-Hodgkin lymphoma, pet dog model, P-glycoprotein

Mifamurtide and TAM-like macrophages: effect on proliferation, migration and differentiation of osteosarcoma cells Research Paper

Francesca Punzo, Giulia Bellini, Chiara Tortora, Daniela Di Pinto, Maura Argenziano, Elvira Pota, Alessandra Di Paola, Martina Di Martino, Francesca Rossi

Published Feb 18, 2020 · Vol. 11, No. 7 · pp. 687-698

Keywords: macrophage polarization, tumor micro-environment, osteosarcoma, Mifamurtide, MG63

In vitro studies on CNGRC-CPG2 fusion proteins for ligand-directed enzyme prodrug therapy for targeted cancer therapy Research Paper

Layla Al-mansoori, Sara S. Bashraheel, Alanod D. Al Qahtani, C. David O’Connor, Philip Elsinga, Sayed K. Goda

Published Feb 11, 2020 · Vol. 11, No. 6 · pp. 619-633

Keywords: targeted cancer therapy, carboxypeptidase G2, glucarpidase, ligand directed enzyme prodrug therapy, antibody directed enzyme prodrug therapy

Human insulin modulates α-synuclein aggregation via DAF-2/DAF-16 signalling pathway by antagonising DAF-2 receptor in C. elegans model of Parkinson’s disease Research Paper

Rizwanul Haque, Shamsuzzama, Lalit Kumar, Tanuj Sharma, Soobiya Fatima, Pooja Jadiya, Mohammad I. Siddiqi, Aamir Nazir

Published Feb 11, 2020 · Vol. 11, No. 6 · pp. 634-649

Keywords: Parkinson’s, human insulin, aggregation, Daf-2, Caenorhabditis elegans (C. elegans)

Identification of molecular targets for the targeted treatment of gastric cancer using dasatinib Research Paper

Raquel Carvalho Montenegro, Alison Howarth, Alessandro Ceroni, Vita Fedele, Batoul Farran, Felipe Pantoja Mesquita, Martin Frejno, Benedict-Tilman Berger, Stephanie Heinzlmeir, Heba Z. Sailem, Roberta Tesch, Daniel Ebner, Stefan Knapp, Rommel Burbano, Bernhard Kuster, Susanne Müller

Published Feb 4, 2020 · Vol. 11, No. 5 · pp. 535-549

Keywords: gastric cancer, dasatinib, biomarker, SRC-kinases, SIK2

Preclinical activity of sacituzumab govitecan (IMMU-132) in uterine and ovarian carcinosarcomas Research Paper

Salvatore Lopez, Emanuele Perrone, Stefania Bellone, Elena Bonazzoli, Burak Zeybek, Chanhee Han, Joan Tymon-Rosario, Gary Altwerger, Gulden Menderes, Anna Bianchi, Luca Zammataro, Aranzazu Manzano, Paola Manara, Elena Ratner, Dan-Arin Silasi, Gloria S. Huang, Masoud Azodi, Peter E. Schwartz, Francesco Raspagliesi, Roberto Angioli, Natalia Buza, Pei Hui, Heather M. Bond, Alessandro D. Santin

Published Feb 4, 2020 · Vol. 11, No. 5 · pp. 560-570

Keywords: sacituzumab govitecan, IMMU-132, uterine carcinosarcoma, trop-2

Calcitriol and non-calcemic vitamin D analogue, 22-oxacalcitriol, attenuate developmental and pathological choroidal vasculature angiogenesis ex vivo and in vivo Research Paper

Stephanie L. Merrigan, Bomina Park, Zaheer Ali, Lasse D. Jensen, Timothy W. Corson, Breandán N. Kennedy

Published Feb 4, 2020 · Vol. 11, No. 5 · pp. 493-509

Keywords: developmental angiogenesis, pathological angiogenesis, ocular angiogenesis, calcitriol, 22-oxacalcitriol

Tumor secreted ANGPTL2 facilitates recruitment of neutrophils to the lung to promote lung pre-metastatic niche formation and targeting ANGPTL2 signaling affects metastatic disease Research Paper

Manish Charan, Piyush Dravid, Maren Cam, Bhuvana Setty, Ryan D. Roberts, Peter J. Houghton, Hakan Cam

Published Feb 4, 2020 · Vol. 11, No. 5 · pp. 510-522

Keywords: pre-metastatic niche formation, osteosarcoma, ANGPTL2, tumor microenvironment, neutrophils

Patient-derived glioblastoma cultures as a tool for small-molecule drug discovery Research Paper

Ling F. Ye, Eduard Reznik, Joshua M. Korn, Fallon Lin, Guizhi Yang, Kimberly Malesky, Hui Gao, Alice Loo, Raymond Pagliarini, Tom Mikkelsen, Donald C. Lo, Ana C. deCarvalho, Brent R. Stockwell

Published Jan 28, 2020 · Vol. 11, No. 4 · pp. 443-451

Keywords: cell death, chemical biology, glioma, cancer

Clostridium perfringens enterotoxin induces claudin-4 to activate YAP in oral squamous cell carcinomas Research Paper

Chie Nakashima, Kazuhiko Yamamoto, Shingo Kishi, Takamitsu Sasaki, Hitoshi Ohmori, Rina Fujiwara-Tani, Shiori Mori, Isao Kawahara, Yukiko Nishiguchi, Takuya Mori, Masuo Kondoh, Yi Luo, Tadaaki Kirita, Hiroki Kuniyasu

Published Jan 28, 2020 · Vol. 11, No. 4 · pp. 309-321

Keywords: clostridium perfringens enterotoxin, claudin-4, YAP, Hippo signal, oral squamous cell carcinoma, Pathology

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

Wayne D. Blosser, Jack A. Dempsey, Ann M. McNulty, Xi Rao, Philip J. Ebert, Caitlin D. Lowery, Philip W. Iversen, Yue Wang Webster, Gregory P. Donoho, Xueqian Gong, Farhana F. Merzoug, Sean Buchanan, Karsten Boehnke, Chunping Yu, Xin Tian You, Richard P. Beckmann, Wenjuan Wu, Samuel C. McNeely, Aimee Bence Lin, Ricardo Martinez

Published Jan 21, 2020 · Vol. 11, No. 3 · pp. 216-236

Keywords: CHK1, prexasertib, replication stress, replication fork, innate immunity

Deregulation of cancer-stem-cell-associated miRNAs in tissues and sera of colorectal cancer patients Research Paper

Cristiano Farace, Andrea Pisano, Carmen Griñan-Lison, Giuliana Solinas, Gema Jiménez, Marina Serra, Esmeralda Carrillo, Fabrizio Scognamillo, Federico Attene, Andrea Montella, Juan Antonio Marchal, Roberto Madeddu

Published Jan 14, 2020 · Vol. 11, No. 2 · pp. 116-130

Keywords: colorectal cancer, metastasis, cancer stem cell, microRNA, biomarker

Circulating tumor DNA analysis in the era of precision oncology Review

Rabih Said, Nicolas Guibert, Geoffrey R. Oxnard, Apostolia M. Tsimberidou

Published Jan 14, 2020 · Vol. 11, No. 2 · pp. 188-211

Keywords: circulating tumor DNA analysis, clinical trials, targeted therapy, genomic profiling

Isolation and characterization of a CD34⁺ sub-clone in B-cell lymphoma Research Paper

Ayad M. Al-Katib, Abdul Shukkur Ebrahim, Mustapha Kandouz, Feras Zaiem, Ali Raufi, Salah Ebrahim, Anwar Mohamed, Nada Emara, Ali M. Gabali

Published Jan 14, 2020 · Vol. 11, No. 2 · pp. 148-160

Keywords: CD34, B-cell non-Hodgkin’s lymphoma, minimal residual disease, lymphoma stem cell

Correction: Inhibition of thioredoxin 1 leads to apoptosis in drug-resistant multiple myeloma Correction

Prahlad V. Raninga, Giovanna Di Trapani, Slavica Vuckovic, Maneet Bhatia, Kathryn F. Tonissen

Published Jan 13, 2020 · Vol. 12, No. 9 · pp. 948-949

Novel functional anti-HER3 monoclonal antibodies with potent anti-cancer effects on various human epithelial cancers Research Paper

Kouki Okita, Shogo Okazaki, Shinya Uejima, Erina Yamada, Hiroki Kaminaka, Misa Kondo, Shiho Ueda, Ryo Tokiwa, Nami Iwata, Akitaka Yamasaki, Natsumi Hayashi, Dai Ogura, Kenji Hirotani, Toshiaki Yoshioka, Masahiro Inoue, Kazue Masuko, Takashi Masuko

Published Jan 7, 2020 · Vol. 11, No. 1 · pp. 31-45

Keywords: CDR, HER3, internalization, mAb, NRG1

The synergistic inhibitory effect of combining therapies targeting EGFR and mitochondria in sarcomas Research Paper

Xiaochun Wang, Reichelle X. Yeo, Philip J. Hogg, David Goldstein, Philip Crowe, Pierre J. Dilda, Jia-Lin Yang

Published Jan 7, 2020 · Vol. 11, No. 1 · pp. 46-61

Keywords: EGFR-targeted therapy, mitochondria inhibitor, tumour metabolism inhibition, sarcomas, combination therapy

Toxoplasma gondii GRA8-derived peptide immunotherapy improves tumor targeting of colorectal cancer Research Paper

Jae-Sung Kim, Daeun Lee, Donggyu Kim, Seok-Jun Mun, Euni Cho, Wooic Son, Chul-Su Yang

Published Jan 7, 2020 · Vol. 11, No. 1 · pp. 62-73

Keywords: Toxoplasma gondii GRA8 peptide, mitochondria, tumor-targeting, metabolism

A novel function of AAA-ATPase p97/VCP in the regulation of cell motility Research Paper

Zi-Jia Khong, Soak-Kuan Lai, Cheng-Gee Koh, Susana Geifman-Shochat, Hoi-Yeung Li

Published Jan 7, 2020 · Vol. 11, No. 1 · pp. 74-85

Keywords: p97/VCP, AAA-ATPase, ROCK, RhoA, cell motility

Thymoquinone induces apoptosis and DNA damage in 5-Fluorouracil-resistant colorectal cancer stem/progenitor cells Research Paper

Farah Ballout, Alissar Monzer, Maamoun Fatfat, Hala El Ouweini, Miran A. Jaffa, Rana Abdel-Samad, Nadine Darwiche, Wassim Abou-Kheir, Hala Gali-Muhtasib

Published Jan 3, 2020 · Vol. 11, No. 31 · pp. 2959-2972

Keywords: thymoquinone, colorectal cancer stem cells, 5-Fluorouracil resistance, colonospheres, apoptosis

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Randomized, double-blind trial of F14512, a polyamine-vectorized anticancer drug, compared with etoposide phosphate, in dogs with naturally occurring lymphoma Research Paper

Mifamurtide and TAM-like macrophages: effect on proliferation, migration and differentiation of osteosarcoma cells Research Paper

In vitro studies on CNGRC-CPG2 fusion proteins for ligand-directed enzyme prodrug therapy for targeted cancer therapy Research Paper

Human insulin modulates α-synuclein aggregation via DAF-2/DAF-16 signalling pathway by antagonising DAF-2 receptor in C. elegans model of Parkinson’s disease Research Paper

Identification of molecular targets for the targeted treatment of gastric cancer using dasatinib Research Paper

Preclinical activity of sacituzumab govitecan (IMMU-132) in uterine and ovarian carcinosarcomas Research Paper

Calcitriol and non-calcemic vitamin D analogue, 22-oxacalcitriol, attenuate developmental and pathological choroidal vasculature angiogenesis ex vivo and in vivo Research Paper

Tumor secreted ANGPTL2 facilitates recruitment of neutrophils to the lung to promote lung pre-metastatic niche formation and targeting ANGPTL2 signaling affects metastatic disease Research Paper

Patient-derived glioblastoma cultures as a tool for small-molecule drug discovery Research Paper

Clostridium perfringens enterotoxin induces claudin-4 to activate YAP in oral squamous cell carcinomas Research Paper

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

Deregulation of cancer-stem-cell-associated miRNAs in tissues and sera of colorectal cancer patients Research Paper

Circulating tumor DNA analysis in the era of precision oncology Review

Isolation and characterization of a CD34⁺ sub-clone in B-cell lymphoma Research Paper

Correction: Inhibition of thioredoxin 1 leads to apoptosis in drug-resistant multiple myeloma Correction

Novel functional anti-HER3 monoclonal antibodies with potent anti-cancer effects on various human epithelial cancers Research Paper

The synergistic inhibitory effect of combining therapies targeting EGFR and mitochondria in sarcomas Research Paper

Toxoplasma gondii GRA8-derived peptide immunotherapy improves tumor targeting of colorectal cancer Research Paper

A novel function of AAA-ATPase p97/VCP in the regulation of cell motility Research Paper

Thymoquinone induces apoptosis and DNA damage in 5-Fluorouracil-resistant colorectal cancer stem/progenitor cells Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Randomized, double-blind trial of F14512, a polyamine-vectorized anticancer drug, compared with etoposide phosphate, in dogs with naturally occurring lymphoma Research Paper

Mifamurtide and TAM-like macrophages: effect on proliferation, migration and differentiation of osteosarcoma cells Research Paper

In vitro studies on CNGRC-CPG2 fusion proteins for ligand-directed enzyme prodrug therapy for targeted cancer therapy Research Paper

Human insulin modulates α-synuclein aggregation via DAF-2/DAF-16 signalling pathway by antagonising DAF-2 receptor in C. elegans model of Parkinson’s disease Research Paper

Identification of molecular targets for the targeted treatment of gastric cancer using dasatinib Research Paper

Preclinical activity of sacituzumab govitecan (IMMU-132) in uterine and ovarian carcinosarcomas Research Paper

Calcitriol and non-calcemic vitamin D analogue, 22-oxacalcitriol, attenuate developmental and pathological choroidal vasculature angiogenesis ex vivo and in vivo Research Paper

Tumor secreted ANGPTL2 facilitates recruitment of neutrophils to the lung to promote lung pre-metastatic niche formation and targeting ANGPTL2 signaling affects metastatic disease Research Paper

Patient-derived glioblastoma cultures as a tool for small-molecule drug discovery Research Paper

Clostridium perfringens enterotoxin induces claudin-4 to activate YAP in oral squamous cell carcinomas Research Paper

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

Deregulation of cancer-stem-cell-associated miRNAs in tissues and sera of colorectal cancer patients Research Paper

Circulating tumor DNA analysis in the era of precision oncology Review

Isolation and characterization of a CD34+ sub-clone in B-cell lymphoma Research Paper

Correction: Inhibition of thioredoxin 1 leads to apoptosis in drug-resistant multiple myeloma Correction

Novel functional anti-HER3 monoclonal antibodies with potent anti-cancer effects on various human epithelial cancers Research Paper

The synergistic inhibitory effect of combining therapies targeting EGFR and mitochondria in sarcomas Research Paper

Toxoplasma gondii GRA8-derived peptide immunotherapy improves tumor targeting of colorectal cancer Research Paper

A novel function of AAA-ATPase p97/VCP in the regulation of cell motility Research Paper

Thymoquinone induces apoptosis and DNA damage in 5-Fluorouracil-resistant colorectal cancer stem/progenitor cells Research Paper

Isolation and characterization of a CD34⁺ sub-clone in B-cell lymphoma Research Paper