The Oncosearch | Oncotarget

Molecular imaging reveals biodistribution of P-cadherin LP-DART bispecific and trafficking of adoptively transferred T cells in mouse xenograft model Research Paper

Vijay R. Gupta, Adam Root, Timothy Fisher, Rand Norberg, John David, Tracey Clark, Justin Cohen, Chad May, Anand Giddabasappa

Published Apr 14, 2020 · Vol. 11, No. 15 · pp. 1344-1357

Keywords: bispecific antibody, tumor targeting, biodistribution, T cells, molecular imaging

Superior cancer preventive efficacy of low versus high dose of mTOR inhibitor in a mouse model of prostate cancer Research Paper

Marina P. Antoch, Michelle Wrobel, Bryan Gillard, Karen K. Kuropatwinski, Ilia Toshkov, Anatoli S. Gleiberman, Ellen Karasik, Michael T. Moser, Barbara A. Foster, Ekaterina L. Andrianova, Olga V. Chernova, Andrei V. Gudkov

Published Apr 14, 2020 · Vol. 11, No. 15 · pp. 1373-1387

Keywords: prostate cancer, rapamycin, prevention, mTOR, PTEN

Proteomic analysis of combined IGF1 receptor targeted therapy and chemotherapy identifies signatures associated with survival in breast cancer patients Research Paper

Tali Sinai-Livne, Metsada Pasmanik-Chor, Zoya Cohen, Ilan Tsarfaty, Haim Werner, Raanan Berger

Published Apr 13, 2020 · Vol. 11, No. 17 · pp. 1515-1530

Keywords: insulin-like growth factor-1 (IGF1), IGF1 receptor (IGF1R), targeted therapy, breast cancer, proteomic analysis

First-in-human study of anticancer immunotherapy drug candidate mobilan: safety, pharmacokinetics and pharmacodynamics in prostate cancer patients Research Paper

Natalia V. Eremina, Vasily I. Kazey, Sergey V. Mishugin, Roman V. Leonenkov, Dmitry Y. Pushkar, Vadim L. Mett, Andrei V. Gudkov

Published Apr 7, 2020 · Vol. 11, No. 14 · pp. 1273-1288

Keywords: prostate cancer, immunotherapy, mobilan, adenoviral vector, intratumor injection

Inhibition of SYK kinase does not confer a pro-proliferative or pro-invasive phenotype in breast epithelium or breast cancer cells Research Paper

David J. Lamb, Aleksander Rust, Albin Rudisch, Tobias Glüxam, Nathalie Harrer, Herwig Machat, Ingrid Christ, Florian Colbatzky, Andreas Wernitznig, Annika Osswald, Wolfgang Sommergruber

Published Apr 7, 2020 · Vol. 11, No. 14 · pp. 1257-1272

Keywords: SYK inhibitor, breast carcinoma, 3D culture, murine mammary gland, proliferation

Th1 cytokines in conjunction with pharmacological Akt inhibition potentiate apoptosis of breast cancer cells in vitro and suppress tumor growth in vivo Research Paper

Loral Showalter, Brian J. Czerniecki, Gary K. Koski

Published Apr 1, 2020 · Vol. 11, No. 30 · pp. 2873-2888

Keywords: breast cancer, Akt kinase, immunotherapy

Investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish Research Paper

Hyejeong Rosemary Kim, Kirankumar Santhakumar, Eleanor Markham, Davide Baldera, David Greenald, Helen E. Bryant, Sherif F. El-Khamisy, Fredericus J. van Eeden

Published Mar 31, 2020 · Vol. 11, No. 13 · pp. 1109-1130

Keywords: Hif, Vhl, DNA repair, apoptosis, chemo/radio-resistance

Exosome mediated miR-155 delivery confers cisplatin chemoresistance in oral cancer cells via epithelial-mesenchymal transition Research Paper

Prathibha Kirave, Piyush Gondaliya, Bhagyashri Kulkarni, Rakesh Rawal, Rachana Garg, Alok Jain, Kiran Kalia

Published Mar 31, 2020 · Vol. 11, No. 13 · pp. 1157-1171

Keywords: cisplatin chemoresistance, miRNA155, exosomes, oral cancer, apoptosis

Origin and role of hepatic myofibroblasts in hepatocellular carcinoma Review

Betul Gok Yavuz, Roberto Carmagnani Pestana, Yehia I. Abugabal, Sunil Krishnan, Jian Chen, Manal M. Hassan, Robert A. Wolff, Asif Rashid, Hesham M. Amin, Ahmed O. Kaseb

Published Mar 31, 2020 · Vol. 11, No. 13 · pp. 1186-1201

Keywords: hepatocellular carcinoma, stellate cells, myofibroblasts, liver fibrosis, immunotherapy

Sirolimus-eluting stents: opposite in vitro effects on the clonogenic cell potential on a long-term exposure Research Paper

Francesco Vasuri, Alessio Degiovanni, Mauro Gargiulo, William G. Thilly, Elena V. Gostjeva, Gianandrea Pasquinelli, Silvia Fittipaldi

Published Mar 30, 2020 · Vol. 11, No. 31 · pp. 2973-2981

Keywords: atherosclerosis, cell proliferation, sirolimus, stents

Correction: Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes Correction

Faruck L. Hakkim, Hamid A. Bakshi, Shabia Khan, Mohamed M. Nasef, Rabia Farzand, Smitha Sam, Luay Rashan, Mohammed S. Al-Baloshi, Sidgi Syed Anwar Abdo Hasson, Ali Al Jabri, Paul A. McCarron, Murtaza M. Tambuwala

Published Mar 23, 2020 · Vol. 11, No. 23 · pp. 2259-2261

DOT1L inhibition is lethal for multiple myeloma due to perturbation of the endoplasmic reticulum stress pathway Research Paper

Caroline Dafflon, Swann Gaulis, Louise Barys, Karen Kapur, Vanessa Cornacchione, Lina Schukur, Sebastian Bergling, Elisabetta Traggiai, Selina Jansky, Leon Hellmann, Barbara Schacher Engstler, Grainne Kerr, Antoine de Weck, David A. Ruddy, Ulrike Naumann, Frédéric Stauffer, Christoph Gaul, Ying Lin, Eric Billy, Andreas Weiss, Francesco Hofmann, Moriko Ito, Ralph Tiedt

Published Mar 17, 2020 · Vol. 11, No. 11 · pp. 956-968

Keywords: DOT1L, multiple myeloma, epigenetics, histone methylation, unfolded protein response

Targeting PI3Kβ alone and in combination with chemotherapy or immunotherapy in tumors with PTEN loss Research Paper

Nicci Owusu-Brackett, Ming Zhao, Argun Akcakanat, Kurt W. Evans, Erkan Yuca, Ecaterina Ileana Dumbrava, Filip Janku, Funda Meric-Bernstam

Published Mar 17, 2020 · Vol. 11, No. 11 · pp. 969-981

Keywords: PI3Kβ, PTEN loss, AZD8186, chemotherapy, immunotherapy

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

Cristina Kinahan, Michael A. Mangone, Luigi Scotto, Michele Visentin, Enrica Marchi, Hearn Jay Cho, Owen A. O’Connor

Published Feb 26, 2020 · Vol. 11, No. 18 · pp. 1576-1589

Keywords: antifolate, multiple myeloma, pralatrexate, biomarker, reduced folate carrier (RFC)

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

Cristina Kinahan, Michael A. Mangone, Luigi Scotto, Michele Visentin, Enrica Marchi, Hearn Jay Cho, Owen A. O’Connor

Published Feb 26, 2020

Keywords: antifolate, multiple myeloma, pralatrexate, biomarker, reduced folate carrier (RFC)

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

Cristina Kinahan, Michael A. Mangone, Luigi Scotto, Michele Visentin, Enrica Marchi, Hearn Jay Cho, Owen A. O’Connor

Published Feb 26, 2020

Keywords: antifolate, multiple myeloma, pralatrexate, biomarker, reduced folate carrier (RFC)

Correction: Trop-2 is a novel target for solid cancer therapy with sacituzumab govitecan (IMMU-132), an antibody-drug conjugate (ADC)* Correction

David M. Goldenberg, Thomas M. Cardillo, Serengulam V. Govindan, Edmund A. Rossi, Robert M. Sharkey

Published Feb 25, 2020 · Vol. 11, No. 10 · pp. 942-942

SLC25A32 sustains cancer cell proliferation by regulating flavin adenine nucleotide (FAD) metabolism Research Paper

Valeria Santoro, Ilya Kovalenko, Kim Vriens, Stefan Christen, Andreas Bernthaler, Andrea Haegebarth, Sarah-Maria Fendt, Sven Christian

Published Feb 25, 2020 · Vol. 11, No. 8 · pp. 801-812

Keywords: transporter, mitochondria, metabolism, ROS, FAD

Prolyl 4-hydroxylase alpha 1 protein expression risk-stratifies early stage colorectal cancer Research Paper

Atsushi Tanaka, Yihua Zhou, Jinru Shia, Fiona Ginty, Makiko Ogawa, David S. Klimstra, Ronald C. Hendrickson, Julia Y. Wang, Michael H. Roehrl

Published Feb 25, 2020 · Vol. 11, No. 8 · pp. 813-824

Keywords: P4HA1, colorectal cancer, biomarker, prognosis, pathology

EB1-dependent long survival of glioblastoma-grafted mice with the oral tubulin-binder BAL101553 is associated with inhibition of tumor angiogenesis Research Paper

Raphaël Bergès, Aurélie Tchoghandjian, Arnauld Sergé, Stéphane Honoré, Dominique Figarella-Branger, Felix Bachmann, Heidi A. Lane, Diane Braguer

Published Feb 25, 2020 · Vol. 11, No. 8 · pp. 759-774

Keywords: glioblastoma, cancer stem cells, microtubule-targeting agent, experimental cancer therapeutics

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Molecular imaging reveals biodistribution of P-cadherin LP-DART bispecific and trafficking of adoptively transferred T cells in mouse xenograft model Research Paper

Superior cancer preventive efficacy of low versus high dose of mTOR inhibitor in a mouse model of prostate cancer Research Paper

Proteomic analysis of combined IGF1 receptor targeted therapy and chemotherapy identifies signatures associated with survival in breast cancer patients Research Paper

First-in-human study of anticancer immunotherapy drug candidate mobilan: safety, pharmacokinetics and pharmacodynamics in prostate cancer patients Research Paper

Inhibition of SYK kinase does not confer a pro-proliferative or pro-invasive phenotype in breast epithelium or breast cancer cells Research Paper

Th1 cytokines in conjunction with pharmacological Akt inhibition potentiate apoptosis of breast cancer cells in vitro and suppress tumor growth in vivo Research Paper

Investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish Research Paper

Exosome mediated miR-155 delivery confers cisplatin chemoresistance in oral cancer cells via epithelial-mesenchymal transition Research Paper

Origin and role of hepatic myofibroblasts in hepatocellular carcinoma Review

Sirolimus-eluting stents: opposite in vitro effects on the clonogenic cell potential on a long-term exposure Research Paper

Correction: Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes Correction

DOT1L inhibition is lethal for multiple myeloma due to perturbation of the endoplasmic reticulum stress pathway Research Paper

Targeting PI3Kβ alone and in combination with chemotherapy or immunotherapy in tumors with PTEN loss Research Paper

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

Correction: Trop-2 is a novel target for solid cancer therapy with sacituzumab govitecan (IMMU-132), an antibody-drug conjugate (ADC)* Correction

SLC25A32 sustains cancer cell proliferation by regulating flavin adenine nucleotide (FAD) metabolism Research Paper

Prolyl 4-hydroxylase alpha 1 protein expression risk-stratifies early stage colorectal cancer Research Paper

EB1-dependent long survival of glioblastoma-grafted mice with the oral tubulin-binder BAL101553 is associated with inhibition of tumor angiogenesis Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Molecular imaging reveals biodistribution of P-cadherin LP-DART bispecific and trafficking of adoptively transferred T cells in mouse xenograft model Research Paper

Superior cancer preventive efficacy of low versus high dose of mTOR inhibitor in a mouse model of prostate cancer Research Paper

Proteomic analysis of combined IGF1 receptor targeted therapy and chemotherapy identifies signatures associated with survival in breast cancer patients Research Paper

First-in-human study of anticancer immunotherapy drug candidate mobilan: safety, pharmacokinetics and pharmacodynamics in prostate cancer patients Research Paper

Inhibition of SYK kinase does not confer a pro-proliferative or pro-invasive phenotype in breast epithelium or breast cancer cells Research Paper

Th1 cytokines in conjunction with pharmacological Akt inhibition potentiate apoptosis of breast cancer cells in vitro and suppress tumor growth in vivo Research Paper

Investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish Research Paper

Exosome mediated miR-155 delivery confers cisplatin chemoresistance in oral cancer cells via epithelial-mesenchymal transition Research Paper

Origin and role of hepatic myofibroblasts in hepatocellular carcinoma Review

Sirolimus-eluting stents: opposite in vitro effects on the clonogenic cell potential on a long-term exposure Research Paper

Correction: Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes Correction

DOT1L inhibition is lethal for multiple myeloma due to perturbation of the endoplasmic reticulum stress pathway Research Paper

Targeting PI3Kβ alone and in combination with chemotherapy or immunotherapy in tumors with PTEN loss Research Paper

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

Correction: Trop-2 is a novel target for solid cancer therapy with sacituzumab govitecan (IMMU-132), an antibody-drug conjugate (ADC)* Correction

SLC25A32 sustains cancer cell proliferation by regulating flavin adenine nucleotide (FAD) metabolism Research Paper

Prolyl 4-hydroxylase alpha 1 protein expression risk-stratifies early stage colorectal cancer Research Paper

EB1-dependent long survival of glioblastoma-grafted mice with the oral tubulin-binder BAL101553 is associated with inhibition of tumor angiogenesis Research Paper