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Lipid tethering of breast tumor cells enables real-time imaging of free-floating cell dynamics and drug response. See Chakrabarti et al. Image courtesy of S. Martin and K. Chakrabarti
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Table of Contents
Editorial
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| Neurons and guidance cues in retinal vascular diseases |
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https://doi.org/10.18632/oncotarget.7413
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| 9618-9619 |
Research Papers: Gerotarget (Focus on Aging)
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| Improved cell metabolism prolongs photoreceptor survival upon retinalpigmented epithelium loss in the sodium iodate induced model of geographic atrophy |
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https://doi.org/10.18632/oncotarget.7330
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| 9620-9633 |
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| GDF15 contributes to radiationinduced senescence through the ROSmediated p16 pathway in human endothelial cells |
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https://doi.org/10.18632/oncotarget.7457
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| 9634-9644 |
Research Papers: Pathology
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| A followup analysis of positron emission tomography/computed tomography in detecting hidden malignancies at the time of diagnosis of membranous nephropathy |
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https://doi.org/10.18632/oncotarget.7506
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| 9645-9651 |
Research Papers: Immunology
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| Lipopolysaccharide derived from the digestive tract activates inflammatory gene expression and inhibits casein synthesis in the mammary glands of lactating dairy cows |
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https://doi.org/10.18632/oncotarget.7371
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| 9652-9665 |
Research Papers
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| The genetic and genomic background of multiple myeloma patients achieving complete response after induction therapy with bortezomib thalidomide and dexamethasone VTD |
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https://doi.org/10.18632/oncotarget.5718
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| 9666-9679 |
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| Guanylate binding protein1 mediates EGFRvIII and promotes glioblastoma growth in vivo but not in vitro |
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https://doi.org/10.18632/oncotarget.7109
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| 9680-9691 |
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| Yap1 promotes the survival and selfrenewal of breast tumor initiating cells via inhibiting Smad3 signaling |
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https://doi.org/10.18632/oncotarget.6655
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| 9692-9706 |
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| Detection rate of actionable mutations in diverse cancers using a biopsyfree blood circulating tumor cell DNA assay |
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https://doi.org/10.18632/oncotarget.7110
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| 9707-9717 |
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| The dual targeting of insulin and insulinlike growth factor 1 receptor enhances the mTOR inhibitormediated antitumor efficacy in hepatocellular carcinoma |
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https://doi.org/10.18632/oncotarget.6836
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| 9718-9731 |
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| PARP1 inhibition radiosensitizes HNSCC cells deficient in homologous recombination by disabling the DNA replication fork elongation response |
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https://doi.org/10.18632/oncotarget.6947
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| 9732-9741 |
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| Zoledronate blocks geranylgeranylation not farnesylation to suppress human osteosarcoma U2OS cells metastasis by EMT via Rho A activation and FAKinhibited JNK and p38 pathways |
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https://doi.org/10.18632/oncotarget.7138
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| 9742-9758 |
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| Genetic evaluation of BRCA1A complex genes with triplenegative breast cancer susceptibility in Chinese women |
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https://doi.org/10.18632/oncotarget.7112
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| 9759-9772 |
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| Long intergenic noncoding RNA 00152 promotes tumor cell cycle progression by binding to EZH2 and repressing p15 and p21 in gastric cancer |
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https://doi.org/10.18632/oncotarget.6949
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| 9773-9787 |
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| Helicobacter pylori CagA induces tumor suppressor gene hypermethylation by upregulating DNMT1 via AKTNFκB pathway in gastric cancer development |
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https://doi.org/10.18632/oncotarget.7125
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| 9788-9800 |
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| Ablation of Neuropilin 1 from gliomaassociated microglia and macrophages slows tumor progression |
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https://doi.org/10.18632/oncotarget.6877
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| 9801-9814 |
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| Identification of stemlike cells and clinical significance of candidate stem cell markers in gastric cancer |
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https://doi.org/10.18632/oncotarget.6890
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| 9815-9831 |
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| RB/PLK1dependent induced pathway by SLAMF3 expression inhibits mitosis and control hepatocarcinoma cell proliferation |
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https://doi.org/10.18632/oncotarget.6954
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| 9832-9843 |
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| Reelin promotes the adhesion and drug resistance of multiple myeloma cells via integrin β1 signaling and STAT3 |
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https://doi.org/10.18632/oncotarget.7151
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| 9844-9858 |
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| The transcription factor GATA1 and the histone methyltransferase SET7 interact to promote VEGFmediated angiogenesis and tumor growth and predict clinical outcome of breast cancer |
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https://doi.org/10.18632/oncotarget.7126
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| 9859-9875 |
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| Inhibiting receptor tyrosine kinase AXL with small molecule inhibitor BMS777607 reduces glioblastoma growth migration and invasion in vitro and in vivo |
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https://doi.org/10.18632/oncotarget.7130
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| 9876-9889 |
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| JNK pathway inhibition selectively primes pancreatic cancer stem cells to TRAILinduced apoptosis without affecting the physiology of normal tissue resident stem cells |
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https://doi.org/10.18632/oncotarget.7066
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| 9890-9906 |
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| Rh2E2 a novel metabolic suppressor specifically inhibits energybased metabolism of tumor cells |
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https://doi.org/10.18632/oncotarget.6934
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| 9907-9924 |
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| Human plasma metabolomics for identifying differential metabolites and predicting molecular subtypes of breast cancer |
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https://doi.org/10.18632/oncotarget.7155
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| 9925-9938 |
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| Overexpression of TRIM14 promotes tongue squamous cell carcinoma aggressiveness by activating the NFκB signaling pathway |
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https://doi.org/10.18632/oncotarget.6941
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| 9939-9950 |
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| Tumor suppressor microRNAs are downregulated in myelodysplastic syndrome with spliceosome mutations |
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https://doi.org/10.18632/oncotarget.7127
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| 9951-9963 |
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| FYN expression potentiates FLT3ITD induced STAT5 signaling in acute myeloid leukemia |
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https://doi.org/10.18632/oncotarget.7128
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| 9964-9974 |
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| Identification of drugs that restore primary cilium expression in cancer cells |
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https://doi.org/10.18632/oncotarget.7198
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| 9975-9992 |
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| WISP1 promotes VEGFCdependent lymphangiogenesis by inhibiting miR300 in human oral squamous cell carcinoma cells |
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https://doi.org/10.18632/oncotarget.7014
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| 9993-10005 |
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| Identifying molecular genetic features and oncogenic pathways of clear cell renal cell carcinoma through the anatomical PADUA scoring system |
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https://doi.org/10.18632/oncotarget.7129
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| 10006-10014 |
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| ACTP: A webserver for predicting potential targets and relevant pathways of autophagymodulating compounds |
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https://doi.org/10.18632/oncotarget.7015
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| 10015-10022 |
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| CD133 expression may be useful as a prognostic indicator in colorectal cancer a tool for optimizing therapy and supportive evidence for the cancer stem cell hypothesis: a metaanalysis |
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https://doi.org/10.18632/oncotarget.7054
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| 10023-10036 |
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| Cullin 4A CUL4A a direct target of miR9 and miR137 promotes gastric cancer proliferation and invasion by regulating the Hippo signaling pathway |
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https://doi.org/10.18632/oncotarget.7048
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| 10037-10050 |
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| Pancancer analysis of intratumor heterogeneity as a prognostic determinant of survival |
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https://doi.org/10.18632/oncotarget.7067
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| 10051-10063 |
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| Oncogenic Kras confers SAHA resistance by upregulating HDAC6 and cmyc expression |
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https://doi.org/10.18632/oncotarget.7134
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| 10064-10072 |
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| eIF4B is a convergent target and critical effector of oncogenic Pim and PI3K/Akt/mTOR signaling pathways in Abl transformants |
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https://doi.org/10.18632/oncotarget.7164
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| 10073-10089 |
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| CD93 and dystroglycan cooperation in human endothelial cell adhesion and migration |
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https://doi.org/10.18632/oncotarget.7136
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| 10090-10103 |
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| The hormone response element mimic sequence of GAS5 lncRNA is sufficient to induce apoptosis in breast cancer cells |
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https://doi.org/10.18632/oncotarget.7173
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| 10104-10116 |
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| SERPINB1 expression is predictive for sensitivity and outcome of cisplatinbased chemotherapy in melanoma |
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https://doi.org/10.18632/oncotarget.6956
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| 10117-10132 |
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| A functionblocking CD47 antibody suppresses stem cell and EGF signaling in triplenegative breast cancer |
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https://doi.org/10.18632/oncotarget.7100
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| 10133-10152 |
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| Screening the yeast genome for energetic metabolism pathways involved in a phenotypic response to the anticancer agent 3bromopyruvate |
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https://doi.org/10.18632/oncotarget.7174
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| 10153-10173 |
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| Blastic plasmacytoid dendritic cell neoplasm frequently shows occult central nervous system involvement at diagnosis and benefits from intrathecal therapy |
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https://doi.org/10.18632/oncotarget.7101
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| 10174-10181 |
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| Chromothripsislike chromosomal rearrangements induced by ionizing radiation using proton microbeam irradiation system |
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https://doi.org/10.18632/oncotarget.7186
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| 10182-10192 |
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| Prognostic role of serum concentrations of highsensitivity Creactive protein in patients with metastatic colorectal cancer: results from the ITACa trial |
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https://doi.org/10.18632/oncotarget.7166
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| 10193-10202 |
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| Bisleuconothine A a bisindole alkaloid inhibits colorectal cancer cell in vitro and in vivo targeting Wnt signaling |
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https://doi.org/10.18632/oncotarget.7190
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| 10203-10214 |
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| A humanized antibody for imaging immune checkpoint ligand PDL1 expression in tumors |
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https://doi.org/10.18632/oncotarget.7143
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| 10215-10227 |
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| NMU signaling promotes endometrial cancer cell progression by modulating adhesion signaling |
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https://doi.org/10.18632/oncotarget.7169
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| 10228-10242 |
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| ADAM10mediated release of heregulin confers resistance to trastuzumab by activating HER3 |
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https://doi.org/10.18632/oncotarget.7200
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| 10243-10254 |
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| Invasive mouse gastric adenocarcinomas arising from Lgr5+ stem cells are dependent on crosstalk between the Hedgehog/GLI2 and mTOR pathways |
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https://doi.org/10.18632/oncotarget.7182
|
| 10255-10270 |
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| Phenylethyl isothiocyanate reverses cisplatin resistance in biliary tract cancer cells via glutathionylationdependent degradation of Mcl1 |
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https://doi.org/10.18632/oncotarget.7171
|
| 10271-10282 |
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| Rasactivated RSK1 phosphorylates EBP50 to regulate its nuclear localization and promote cell proliferation |
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https://doi.org/10.18632/oncotarget.7184
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| 10283-10296 |
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| miR217 and CAGE form feedback loop and regulates the response to anticancer drugs through EGFR and HER2 |
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https://doi.org/10.18632/oncotarget.7185
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| 10297-10321 |
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| Aberrant gene methylation in nonneoplastic mucosa as a predictive marker of ulcerative colitisassociated CRC |
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https://doi.org/10.18632/oncotarget.7188
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| 10322-10331 |
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| Implication of combined PDL1/PD1 blockade with cytokineinduced killer cells as a synergistic immunotherapy for gastrointestinal cancer |
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https://doi.org/10.18632/oncotarget.7243
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| 10332-10344 |
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| Lovastatin lactone elicits human lung cancer cell apoptosis via a COX2/PPARγdependent pathway |
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https://doi.org/10.18632/oncotarget.7213
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| 10345-10362 |
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| Mechanism of progestin resistance in endometrial precancer/cancer through Nrf2AKR1C1 pathway |
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https://doi.org/10.18632/oncotarget.7004
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| 10363-10372 |
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| Estrogen receptor beta as a prognostic factor in breast cancer patients: A systematic review and metaanalysis |
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https://doi.org/10.18632/oncotarget.7219
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| 10373-10385 |
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| Resistance to the nucleotide analogue cidofovir in HPV+ cells: a multifactorial process involving UMP/CMP kinase 1 |
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https://doi.org/10.18632/oncotarget.7006
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| 10386-10401 |
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| OLA1 contributes to epithelialmesenchymal transition in lung cancer by modulating the GSK3β/snail/Ecadherin signaling |
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https://doi.org/10.18632/oncotarget.7224
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| 10402-10413 |
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| MicroRNA34a promotes genomic instability by a broad suppression of genome maintenance mechanisms downstream of the oncogene KSHVvGPCR |
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https://doi.org/10.18632/oncotarget.7248
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| 10414-10432 |
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| Perlecan/HSPG2 and matrilysin/MMP7 as indices of tissue invasion: tissue localization and circulating perlecan fragments in a cohort of 288 radical prostatectomy patients |
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https://doi.org/10.18632/oncotarget.7197
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| 10433-10447 |
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| Sodium alginate prevents progression of nonalcoholic steatohepatitis and liver carcinogenesis in obese and diabetic mice |
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https://doi.org/10.18632/oncotarget.7249
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| 10448-10458 |
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| Role of heme oxygenase1 in the pathogenesis and tumorigenicity of Kaposi’s sarcomaassociated herpesvirus |
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https://doi.org/10.18632/oncotarget.7227
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| 10459-10471 |
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| The sonic hedgehog signaling pathway stimulates anaplastic thyroid cancer cell motility and invasiveness by activating Akt and cMet |
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https://doi.org/10.18632/oncotarget.7228
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| 10472-10485 |
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| Lipid tethering of breast tumor cells enables realtime imaging of freefloating cell dynamics and drug response |
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https://doi.org/10.18632/oncotarget.7251
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| 10486-10497 |
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| Diallyl disulfide suppresses epithelialmesenchymal transition invasion and proliferation by downregulation of LIMK1 in gastric cancer |
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https://doi.org/10.18632/oncotarget.7252
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| 10498-10512 |
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| Metaanalysis of the differentially expressed microRNA profiles in nasopharyngeal carcinoma |
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https://doi.org/10.18632/oncotarget.7013
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| 10513-10521 |
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| Marked enhancement of lysosomal targeting and efficacy of ErbB2targeted drug delivery by HSP90 inhibition |
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https://doi.org/10.18632/oncotarget.7231
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| 10522-10535 |
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| Quantification of Unmethylated Alu QUAlu: a tool to assess global hypomethylation in routine clinical samples |
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https://doi.org/10.18632/oncotarget.7233
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| 10536-10546 |
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| Nextgeneration sequencing reveals somatic mutations that confer exceptional response to everolimus |
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https://doi.org/10.18632/oncotarget.7234
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| 10547-10556 |
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| Activation of the PD1/PDL1 immune checkpoint confers tumor cell chemoresistance associated with increased metastasis |
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https://doi.org/10.18632/oncotarget.7235
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| 10557-10567 |
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| The status of epidermal growth factor receptor in borderline ovarian tumours |
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https://doi.org/10.18632/oncotarget.7257
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| 10568-10577 |
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| Heterogenous ribonucleoprotein A18 hnRNP A18 promotes tumor growth by increasing protein translation of selected transcripts in cancer cells |
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https://doi.org/10.18632/oncotarget.7020
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| 10578-10593 |
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| Estrogen receptormediated miR4865p regulation of OLFM4 expression in ovarian cancer |
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https://doi.org/10.18632/oncotarget.7236
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| 10594-10605 |
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| Neonatal bisphenol A exposure induces meiotic arrest and apoptosis of spermatogenic cells |
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https://doi.org/10.18632/oncotarget.7218
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| 10606-10615 |
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| Aminomethylphosphonic acid inhibits growth and metastasis of human prostate cancer in an orthotopic xenograft mouse model |
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https://doi.org/10.18632/oncotarget.7055
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| 10616-10626 |
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| PHOX2B is a suppressor of neuroblastoma metastasis |
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https://doi.org/10.18632/oncotarget.7056
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| 10627-10637 |
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| Construction of a new antiCD19 chimeric antigen receptor and the antileukemia function study of the transduced T cells |
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https://doi.org/10.18632/oncotarget.7079
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| 10638-10649 |
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| The expression of presenilin 1 enhances carcinogenesis and metastasis in gastric cancer |
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https://doi.org/10.18632/oncotarget.7298
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| 10650-10662 |
Clinical Research Papers
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| MicroRNA223 and microRNA92a in stool and plasma samples act as complementary biomarkers to increase colorectal cancer detection |
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https://doi.org/10.18632/oncotarget.7119
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| 10663-10675 |
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| Histologybased prediction of lymph node metastases in early gastric cancer as decision guidance for endoscopic resection |
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https://doi.org/10.18632/oncotarget.7221
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| 10676-10683 |
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| Effect of postoperative radiotherapy for squamous cell cancer of the breast in a surveillance epidemiology and end results populationbased study |
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https://doi.org/10.18632/oncotarget.7222
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| 10684-10693 |
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