Vol 6, No 9

CARP-1 / CCAR1: A biphasic regulator of cancer cell growth and apoptosis

Immunostimulatory effects of RACK1 pseudosubstrate in human leukocytes obtained from young and old donors

Protein kinase CK2 is widely expressed in follicular, Burkitt and diffuse large B-cell lymphomas and propels malignant B-cell growth

Pyruvate kinase M2 prevents apoptosis via modulating Bim stability and associates with poor outcome in hepatocellular carcinoma

P-selectin-mediated platelet adhesion promotes tumor growth

Triple Akt inhibition as a new therapeutic strategy in T-cell acute lymphoblastic leukemia

Loss of p21^Cip1/CDKN1A renders cancer cells susceptible to Polo-like kinase 1 inhibition

Osteopontin promotes a cancer stem cell-like phenotype in hepatocellular carcinoma cells via an integrin–NF-κB–HIF-1α pathway

The activity regulation of the mitotic centromere-associated kinesin by Polo-like kinase 1

Elevated S100A6 (Calcyclin) enhances tumorigenesis and suppresses CXCL14-induced apoptosis in clear cell renal cell carcinoma

Fibrillin-1, induced by Aurora-A but inhibited by BRCA2, promotes ovarian cancer metastasis

Caffeic acid phenethyl ester induced cell cycle arrest and growth inhibition in androgen-independent prostate cancer cells via regulation of Skp2, p53, p21Cip1 and p27Kip1

Disruption of BASIGIN decreases lactic acid export and sensitizes non-small cell lung cancer to biguanides independently of the LKB1 status

Efficacy of a Mer and Flt3 tyrosine kinase small molecule inhibitor, UNC1666, in acute myeloid leukemia

Cbl-b inhibits P-gp transporter function by preventing its translocation into caveolae in multiple drug-resistant gastric and breast cancers

Inhibition of non-small cell lung cancer (NSCLC) growth by a novel small molecular inhibitor of EGFR

Computational design, chemical synthesis, and biological evaluation of a novel ERK inhibitor (BL-EI001) with apoptosis-inducing mechanisms in breast cancer

Carbonic anhydrase XII is a new therapeutic target to overcome chemoresistance in cancer cells

Snail and Slug collaborate on EMT and tumor metastasis through miR-101-mediated EZH2 axis in oral tongue squamous cell carcinoma

The histidine-rich calcium binding protein (HRC) promotes tumor metastasis in hepatocellular carcinoma and is upregulated by SATB1

Transcriptome-wide identification and study of cancer-specific splicing events across multiple tumors

Radiation-induced PGE₂ sustains human glioma cell growth and survival through EGF signaling

High expression of TACC3 in esophageal squamous cell carcinoma correlates with poor prognosis

Androgen receptor non-nuclear regulation of prostate cancer cell invasion mediated by Src and matriptase

H89 enhances the sensitivity of cancer cells to glyceryl trinitrate through a purinergic receptor-dependent pathway

G9a is essential for EMT-mediated metastasis and maintenance of cancer stem cell-like characters in head and neck squamous cell carcinoma

Depletion of eIF2·GTP·Met-tRNAi translation initiation complex up-regulates BRCA1 expression in vitro and in vivo

JQ1 suppresses tumor growth through downregulating LDHA in ovarian cancer*

The miR-491-3p/mTORC2/FOXO1 regulatory loop modulates chemo-sensitivity in human tongue cancer

DC120, a novel AKT inhibitor, preferentially suppresses nasopharyngeal carcinoma cancer stem-like cells by downregulating Sox2

ZBRK1, a novel tumor suppressor, activates VHL gene transcription through formation of a complex with VHL and p300 in renal cancer

Distinct anti-oncogenic effect of various microRNAs in different mouse models of liver cancer

Leukemia inhibitory factor receptor is a novel immunomarker in distinction of well-differentiated HCC from dysplastic nodules

The PDGF-D/miR-106a/Twist1 pathway orchestrates epithelial-mesenchymal transition in gemcitabine resistance hepatoma cells

TNKS1BP1 functions in DNA double-strand break repair though facilitating DNA-PKcs autophosphorylation dependent on PARP-1

Gene amplification during differentiation of mammalian neural stem cells in vitro and in vivo

Treatment-induced cell cycle kinetics dictate tumor response to chemotherapy

A direct plasma assay of circulating microRNA-210 of hypoxia can identify early systemic metastasis recurrence in melanoma patients

A selective ATP-competitive sphingosine kinase inhibitor demonstrates anti-cancer properties

Autophagy-based survival prognosis in human colorectal carcinoma

Cytokeratin 5/6 fingerprinting in HER2-positive tumors identifies a poor prognosis and trastuzumab-resistant Basal-HER2 subtype of breast cancer

Sumoylation of HDAC2 promotes NF-κB-dependent gene expression

Both mTORC1 and mTORC2 are involved in the regulation of cell adhesion

High neuropeptide Y release associates with Ewing sarcoma bone dissemination - in vivo model of site-specific metastases

Autophagy induction by leptin contributes to suppression of apoptosis in cancer cells and xenograft model: Involvement of p53/FoxO3A axis

Extension of the in vivo half-life of endostatin and its improved anti-tumor activities upon fusion to a humanized antibody against tumor-associated glycoprotein 72 in a mouse model of human colorectal carcinoma

Inhibition of PI3K/AKT/mTOR axis disrupts oxidative stress-mediated survival of melanoma cells

Association of Fusobacterium species in pancreatic cancer tissues with molecular features and prognosis

Free ISG15 triggers an antitumor immune response against breast cancer: a new perspective

Multiple mechanisms of MYCN dysregulation in Wilms tumour

EGF-reduced Wnt5a transcription induces epithelial-mesenchymal transition via Arf6-ERK signaling in gastric cancer cells

Stratifying risk of recurrence in stage II colorectal cancer using deregulated stromal and epithelial microRNAs

Bee venom inhibits growth of human cervical tumors in mice

Plexin-B2 promotes invasive growth of malignant glioma

H4K12ac is regulated by estrogen receptor-alpha and is associated with BRD4 function and inducible transcription

Genetic and clinical characteristics of primary and secondary glioblastoma is associated with differential molecular subtype distribution

microRNA-29b prevents liver fibrosis by attenuating hepatic stellate cell activation and inducing apoptosis through targeting PI3K/AKT pathway

ColoLipidGene: signature of lipid metabolism-related genes to predict prognosis in stage-II colon cancer patients