|
| GHRHantagonists in TNBC |
|
https://doi.org/10.18632/oncotarget.3271
Jörg B. Engel
|
| 1898-1899 |
|
| Prostate cancer stem cells: deciphering the origins and pathways involved in prostate tumorigenesis and aggression |
|
https://doi.org/10.18632/oncotarget.2953
Adrian P. Rybak, Robert G. Bristow, and Anil Kapoor
|
| 1900-1919 |
|
| Hypoxia induces a lipogenic cancer cell phenotype via HIF1αdependent and independent pathways |
|
https://doi.org/10.18632/oncotarget.3058
Alessandro Valli, Miguel Rodriguez, Loukas Moutsianas, Roman Fischer, Vita Fedele, Hong-Lei Huang, Ruud Van Stiphout, Dylan Jones, Michael Mccarthy, Maria Vinaxia, Kaori Igarashi, Maya Sato, Tomoyoshi Soga, Francesca Buffa, James Mccullagh, Oscar Yanes, Adrian Harris, and Benedikt Kessler
|
| 1920-1941 |
|
| Methylβcyclodextrin upregulates collagen I expression in chronologicallyaged skin via its anticaveolin1 activity |
|
https://doi.org/10.18632/oncotarget.3039
Jung-Ae Lee, Da-In Choi, Jee-Young Choi, Sun-Ok Kim, Kyung-A Cho, Jee-Bum Lee, Sook-Jung Yun, and Seung-Chul Lee
|
| 1942-1953 |
|
| Novel receptor tyrosine kinase targeted combination therapies for imatinibresistant gastrointestinal stromal tumors GIST |
|
https://doi.org/10.18632/oncotarget.3021
Daruka Mahadevan, Noah Theiss, Carla Morales, Amy E. Stejskal, Laurence S. Cooke, Min Zhu, Drew Kurtzman, Rachel Swart, Evan Ong, and Wenqing Qi
|
| 1954-1966 |
|
| Hypoxia/HIF1α induces lapatinib resistance in ERBB2positive breast cancer cells via regulation of DUSP2 |
|
https://doi.org/10.18632/oncotarget.2806
Sergey V. Karakashev, and Mauricio J. Reginato
|
| 1967-1980 |
|
| Group I Paks as therapeutic targets in NF2deficient meningioma |
|
https://doi.org/10.18632/oncotarget.2810
Hoi-Yee Chow, Biao Dong, Sergio G. Duron, David A. Campbell, Christy C. Ong, Klaus P. Hoeflich, Long-Sheng Chang, D. Bradley Welling, Zeng-jie Yang, and Jonathan Chernoff
|
| 1981-1994 |
|
| Neoalbaconol induces cell death through necroptosis by regulating RIPKdependent autocrine TNFα and ROS production |
|
https://doi.org/10.18632/oncotarget.3038
Xinfang Yu, Qipan Deng, Wei Li, Lanbo Xiao, Xiangjian Luo, Xiaolan Liu, Lifang Yang, Songling Peng, Zhihui Ding, Tao Feng, Jian Zhou, Jia Fan, Ann M. Bode, Zigang Dong, Jikai Liu, and Ya Cao
|
| 1995-2008 |
|
| Multiple receptor tyrosine kinase activation attenuates therapeutic efficacy of the fibroblast growth factor receptor 2 inhibitor AZD4547 in FGFR2 amplified gastric cancer |
|
https://doi.org/10.18632/oncotarget.2987
Jinjia Chang, Shanshan Wang, Zhe Zhang, Xinyang Liu, Zheng Wu, Ruixuan Geng, Xiaoxiao Ge, Congqi Dai, Rujiao Liu, Qunling Zhang, Wenhua Li, and Jin Li
|
| 2009-2022 |
|
| Sgo1 is a potential therapeutic target for hepatocellular carcinoma |
|
https://doi.org/10.18632/oncotarget.2764
Lyu-Han Wang, Chia-Jui Yen, Tian-Neng Li, Sabine Elowe, Wen-Ching Wang, and Lily Hui-Ching Wang
|
| 2023-2033 |
|
| Functional repair of p53 mutation in colorectal cancer cells using transsplicing |
|
https://doi.org/10.18632/oncotarget.2988
Xingxing He, Jiazhi Liao, Fang Liu, Junwei Yan, Jingjun Yan, Haitao Shang, Qian Dou, Ying Chang, Jusheng Lin, and Yuhu Song
|
| 2034-2045 |
|
| Claudin7 promotes the epithelial – mesenchymal transition in human colorectal cancer |
|
https://doi.org/10.18632/oncotarget.2858
Rahel Philip, Sarah Heiler, Wei Mu, Markus W. Büchler, Margot Zöller, and Florian Thuma
|
| 2046-2063 |
|
| Amyloid precursorlike protein 2 APLP2 affects the actin cytoskeleton and increases pancreatic cancer growth and metastasis |
|
https://doi.org/10.18632/oncotarget.2990
Poomy Pandey, Satyanarayana Rachagani, Srustidhar Das, Parthasarathy Seshacharyulu, Yuri Sheinin, Naava Naslavsky, Zenggang Pan, Brittney L. Smith, Haley L. Peters, Prakash Radhakrishnan, Nicole R. McKenna, Sai Srinivas Panapakkam Giridharan, Dhanya Haridas, Sukhwinder Kaur, Michael A. Hollingsworth, Richard G. MacDonald, Jane L. Meza, Steve Caplan, Surinder K. Batra, and Joyce C. Solheim
|
| 2064-2075 |
|
| Mesenchymal stem cells are resistant to carbon ion radiotherapy |
|
https://doi.org/10.18632/oncotarget.2857
Nils H. Nicolay, Yingying Liang, Ramon Lopez Perez, Tilman Bostel, Thuy Trinh, Sonevisay Sisombath, Klaus-Josef Weber, Anthony D. Ho, Jürgen Debus, Rainer Saffrich, and Peter E. Huber
|
| 2076-2087 |
|
| mTOR kinase inhibitors synergize with histone deacetylase inhibitors to kill Bcell acute lymphoblastic leukemia cells |
|
https://doi.org/10.18632/oncotarget.2992
Brandon R. Beagle, Duc M. Nguyen, Sharmila Mallya, Sarah S. Tang, Mengrou Lu, Zhihong Zeng, Marina Konopleva, Thanh-Trang Vo, and David A. Fruman
|
| 2088-2100 |
|
| Silencing erythropoietin receptor on glioma cells reinforces efficacy of temozolomide and Xrays through senescence and mitotic catastrophe |
|
https://doi.org/10.18632/oncotarget.2937
Elodie A. Pérès, Aurélie N. Gérault, Samuel Valable, Simon Roussel, Jérôme Toutain, Didier Divoux, Jean-Sébastien Guillamo, Marc Sanson, Myriam Bernaudin, and Edwige Petit
|
| 2101-2119 |
|
| TGFβ1 induces epigenetic silence of TIP30 to promote tumor metastasis in esophageal carcinoma |
|
https://doi.org/10.18632/oncotarget.2940
Fangfang Bu, Xing Liu, Jingjing Li, Shukun Chen, Xin Tong, Chunsheng Ma, Hui Mao, Fei Pan, Xiaoyan Li, Bo Chen, Liyan Xu, Enmin Li, Geng Kou, Jun Han, Shangjing Guo, Jian Zhao, and Yajun Guo
|
| 2120-2133 |
|
| DNA damage induces GDNF secretion in the tumor microenvironment with paracrine effects promoting prostate cancer treatment resistance |
|
https://doi.org/10.18632/oncotarget.3040
Roland M. Huber, Jared M. Lucas, Luis A. Gomez-Sarosi, Ilsa Coleman, Song Zhao, Roger Coleman, and Peter S. Nelson
|
| 2134-2147 |
|
| Targeting a ribonucleoprotein complex containing the caprin1 protein and the cMyc mRNA suppresses tumor growth in mice: an identification of a novel oncotarget |
|
https://doi.org/10.18632/oncotarget.3236
Ya-Qi Qiu, Cheng-Wei Yang, Yue-Zhi Lee, Ruey-Bing Yang, Chih-Hao Lee, Hsing-Yu Hsu, Chien-Chung Chang, and Shiow-Ju Lee
|
| 2148-2163 |
|
| Afatinib induces apoptosis in NSCLC without EGFR mutation through Elk1mediated suppression of CIP2A |
|
https://doi.org/10.18632/oncotarget.2941
Ting-Ting Chao, Cheng-Yi Wang, Yen-Lin Chen, Chih-Cheng Lai, Fang-Yu Chang, Yi-Ting Tsai, Chung-Hao H. Chao, Chung-Wai Shiau, Yuh-Chin T. Huang, Chong-Jen Yu, and Kuen-Feng Chen
|
| 2164-2179 |
|
| γH2AX promotes hepatocellular carcinoma angiogenesis via EGFR/HIF1α/VEGF pathways under hypoxic condition |
|
https://doi.org/10.18632/oncotarget.2942
Heng Xiao, Rongliang Tong, Chaofeng Ding, Zhen Lv, Chengli Du, Chuanhui Peng, Shaobing Cheng, Haiyang Xie, Lin Zhou, Jian Wu, and Shusen Zheng
|
| 2180-2192 |
|
| DCLK1 is a broadly dysregulated target against epithelialmesenchymal transition focal adhesion and stemness in clear cell renal carcinoma |
|
https://doi.org/10.18632/oncotarget.3059
Nathaniel Weygant, Dongfeng Qu, Randal May, Ryan M. Tierney, William L. Berry, Lichao Zhao, Shweta Agarwal, Parthasarathy Chandrakesan, Harisha R. Chinthalapally, Nicholas T. Murphy, James D. Li, Sripathi M. Sureban, Michael J. Schlosser, James J. Tomasek, and Courtney W. Houchen
|
| 2193-2205 |
|
| Hypoxia upregulates SERPINB3 through HIF2α in human liver cancer cells |
|
https://doi.org/10.18632/oncotarget.2943
Stefania Cannito, Cristian Turato, Claudia Paternostro, Alessandra Biasiolo, Sebastiano Colombatto, Irene Cambieri, Santina Quarta, Erica Novo, Elisabetta Morello, Gianmarco Villano, Silvano Fasolato, Tiziana Musso, Ezio David, Ignazia Tusa, Elisabetta Rovida, Riccardo Autelli, Antonina Smedile, Umberto Cillo, Patrizia Pontisso, and Maurizio Parola
|
| 2206-2221 |
|
| SKP2 cooperates with NRas or AKT to induce liver tumor development in mice |
|
https://doi.org/10.18632/oncotarget.2945
Salvatore Delogu, Chunmei Wang, Antonio Cigliano, Kirsten Utpatel, Marcella Sini, Thomas Longerich, Nina Waldburger, Kai Breuhahn, Lijie Jiang, Silvia Ribback, Frank Dombrowski, Matthias Evert, Xin Chen, and Diego F. Calvisi
|
| 2222-2234 |
|
| βIIITubulin: A novel mediator of chemoresistance and metastases in pancreatic cancer |
|
https://doi.org/10.18632/oncotarget.2946
Joshua A. McCarroll, George Sharbeen, Jie Liu, Janet Youkhana, David Goldstein, Nigel McCarthy, Lydia F. Limbri, Dominic Dischl, Güralp O. Ceyhan, Mert Erkan, Amber L. Johns, Andrew V. Biankin, Maria Kavallaris, and Phoebe A. Phillips
|
| 2235-2249 |
|
| Inhibition of HIF1α by PX478 enhances the antitumor effect of gemcitabine by inducing immunogenic cell death in pancreatic ductal adenocarcinoma |
|
https://doi.org/10.18632/oncotarget.2948
Tiansuo Zhao, He Ren, Li Jia, Jing Chen, Wen Xin, Fan Yan, Jing Li, Xiuchao Wang, Song Gao, Dong Qian, Chongbiao Huang, and Jihui Hao
|
| 2250-2262 |
|
| RUNX1 an androgen and EZH2regulated gene has differential roles in ARdependent and independent prostate cancer |
|
https://doi.org/10.18632/oncotarget.2949
Ken-ichi Takayama, Takashi Suzuki, Shuichi Tsutsumi, Tetsuya Fujimura, Tomohiko Urano, Satoru Takahashi, Yukio Homma, Hiroyuki Aburatani, and Satoshi Inoue
|
| 2263-2276 |
|
| MicroRNA26a promotes anoikis in human hepatocellular carcinoma cells by targeting alpha5 integrin |
|
https://doi.org/10.18632/oncotarget.2956
Xiang Zhang, Shu-Li Cheng, Ka Bian, Lei Wang, Xiao Zhang, Bo Yan, Lin-Tao Jia, Jing Zhao, Noor Gammoh, An-Gang Yang, and Rui Zhang
|
| 2277-2289 |
|
| The antimicrobial peptide pardaxin exerts potent antitumor activity against canine perianal gland adenoma |
|
https://doi.org/10.18632/oncotarget.2959
Chieh-Yu Pan, Chao-Nan Lin, Ming-Tang Chiou, Chao Yuan Yu, Jyh-Yih Chen, and Chi-Hsien Chien
|
| 2290-2301 |
|
| Targeting the microRNA21/AP1 axis by 5fluorouracil and pirarubicin in human hepatocellular carcinoma |
|
https://doi.org/10.18632/oncotarget.2955
Xiaodong He, Jingjing Li, Weidong Guo, Wei Liu, Jia Yu, Wei Song, Lei Dong, Fang Wang, Shuangni Yu, Yi Zheng, Songsen Chen, Yan Kong, and Changzheng Liu
|
| 2302-2314 |
|
| By promoting cell differentiation miR100 sensitizes basallike breast cancer stem cells to hormonal therapy |
|
https://doi.org/10.18632/oncotarget.2962
Annalisa Petrelli, Rosachiara Carollo, Marilisa Cargnelutti, Flora Iovino, Maurizio Callari, Daniela Cimino, Matilde Todaro, Laura Rosa Mangiapane, Alessandro Giammona, Adriana Cordova, Filippo Montemurro, Daniela Taverna, Maria Grazia Daidone, Giorgio Stassi, and Silvia Giordano
|
| 2315-2330 |
|
| Immunohistochemical quantification of the cobalamin transport protein cell surface receptor and Ki67 in naturally occurring canine and feline malignant tumors and in adjacent normal tissues |
|
https://doi.org/10.18632/oncotarget.3206
Annette M. Sysel, Victor E. Valli, and Joseph A. Bauer
|
| 2331-2348 |
|
| FOXM1 confers to epithelialmesenchymal transition stemness and chemoresistance in epithelial ovarian carcinoma cells |
|
https://doi.org/10.18632/oncotarget.2957
Wen-Tai Chiu, Yu-Fang Huang, Huei-Yu Tsai, Chien-Chin Chen, Chang-Hwa Chang, Soon-Cen Huang, Keng-Fu Hsu, and Cheng-Yang Chou
|
| 2349-2365 |
|
| The tetraspanins CD151 and Tspan8 are essential exosome components for the crosstalk between cancer initiating cells and their surrounding |
|
https://doi.org/10.18632/oncotarget.2958
Shijing Yue, Wei Mu, Ulrike Erb, and Margot Zöller
|
| 2366-2384 |
|
| The antileukemic activity of sodium dichloroacetate in p53mutated/null cells is mediated by a p53independent ILF3/p21 pathway |
|
https://doi.org/10.18632/oncotarget.2960
Chiara Agnoletto, Laura Brunelli, Elisabetta Melloni, Roberta Pastorelli, Fabio Casciano, Erika Rimondi, Gian Matteo Rigolin, Antonio Cuneo, Paola Secchiero, and Giorgio Zauli
|
| 2385-2396 |
|
| The BRCA1/2directed miRNA signature predicts a good prognosis in ovarian cancer patients with wildtype BRCA1/2 |
|
https://doi.org/10.18632/oncotarget.2963
Yunyan Gu, Mengmeng Zhang, Fuduan Peng, Lei Fang, Yuanyuan Zhang, Haihai Liang, Wenbin Zhou, Lu Ao, and Zheng Guo
|
| 2397-2406 |
|
| Resistance to everolimus driven by epigenetic regulation of MYC in ER+ breast cancers |
|
https://doi.org/10.18632/oncotarget.2964
Teeru Bihani, Scott A. Ezell, Brendon Ladd, Shaun E. Grosskurth, Anne Marie Mazzola, Mark Pietras, Corinne Reimer, Michael Zinda, Stephen Fawell, and Celina M. D’Cruz
|
| 2407-2420 |
|
| MicroRNA135b a HSF1 target promotes tumor invasion and metastasis by regulating RECK and EVI5 in hepatocellular carcinoma |
|
https://doi.org/10.18632/oncotarget.2965
Yan Li, Dan Xu, Chunyang Bao, Yuannv Zhang, Di Chen, Fangyu Zhao, Jie Ding, Linhui Liang, Qifeng Wang, Li Liu, Jinjun Li, Ming Yao, Shenglin Huang, and Xianghuo He
|
| 2421-2433 |
|
| Chloride channel3 promotes tumor metastasis by regulating membrane ruffling and is associated with poor survival |
|
https://doi.org/10.18632/oncotarget.2966
Bin Xu, Xiaobao Jin, Ling Min, Qin Li, Lulu Deng, Hui Wu, Guixian Lin, Lixin Chen, Haifeng Zhang, Chunmei Li, Liwei Wang, Jiayong Zhu, Weizhang Wang, Fujiang Chu, Juan Shen, Hongzhi Li, and Jianwen Mao
|
| 2434-2450 |
|
| Metabolic reprogramming of metastatic breast cancer and melanoma by let7a microRNA |
|
https://doi.org/10.18632/oncotarget.3235
Anastassia Serguienko, Iwona Grad, Anna B. Wennerstrøm, Leonardo A. Meza-Zepeda, Bernd Thiede, Eva W. Stratford, Ola Myklebost, and Else Munthe
|
| 2451-2465 |
|
| Genetic alterations of histone lysine methyltransferases and their significance in breast cancer |
|
https://doi.org/10.18632/oncotarget.2967
Lanxin Liu, Sarah Kimball, Hui Liu, Andreana Holowatyj, and Zeng-Quan Yang
|
| 2466-2482 |
|
| MicroRNA500 sustains nuclear factorκB activation and induces gastric cancer cell proliferation and resistance to apoptosis |
|
https://doi.org/10.18632/oncotarget.2800
Liang Zhang, Ya Ding, Zhongyu Yuan, Junling Liu, Jian Sun, Fangyong Lei, Shu Wu, Su Li, and Dongsheng Zhang
|
| 2483-2495 |
|
| Clinically relevant genes and regulatory pathways associated with NRASQ61 mutations in melanoma through an integrative genomics approach |
|
https://doi.org/10.18632/oncotarget.2954
Wei Jiang, Peilin Jia, Katherine E. Hutchinson, Douglas B. Johnson, Jeffrey A. Sosman, and Zhongming Zhao
|
| 2496-2508 |
|
| Stabilization of LKB1 and Akt by neddylation regulates energy metabolism in liver cancer |
|
https://doi.org/10.18632/oncotarget.3191
LucÃa Barbier-Torres, Teresa C. Delgado, Juan L. GarcÃa-RodrÃguez, Imanol Zubiete-Franco, David Fernández-Ramos, Xabier Buqué, Ainara Cano, Virginia Gutiérrez-de Juan, Itziar Fernández-DomÃnguez, Fernando Lopitz-Otsoa, Pablo Fernández-Tussy, Loreto Boix, Jordi Bruix, Erica Villa, Azucena Castro, Shelly C. Lu, Patricia Aspichueta, Dimitris Xirodimas, Marta Varela-Rey, José M. Mato, Naiara Beraza, and MarÃa L. MartÃnez-Chantar
|
| 2509-2523 |
|
| Mutation of Vav1 adaptor region reveals a new oncogenic activation |
|
https://doi.org/10.18632/oncotarget.2629
Lyra Razanadrakoto, Françoise Cormier, Vanessa Laurienté, Elisabetta Dondi, Laura Gardano, Shulamit Katzav, Lionel Guittat, and Nadine Varin-Blank
|
| 2524-2538 |
|
| Coexpression of PKM2 and TRIM35 predicts survival and recurrence in hepatocellular carcinoma |
|
https://doi.org/10.18632/oncotarget.2991
Zhiao Chen, Xinyuan Lu, Zhichao Wang, Guangzhi Jin, Qifeng Wang, Di Chen, Taoyang Chen, Jinjun Li, Jia Fan, Wenming Cong, Qiang Gao, and Xianghuo He
|
| 2539-2548 |
|
| Mutation profiling of tumor DNA from plasma and tumor tissue of colorectal cancer patients with a novel highsensitivity multiplexed mutation detection platform |
|
https://doi.org/10.18632/oncotarget.3041
Evelyn Kidess, Kyra Heirich, Matthew Wiggin, Valentina Vysotskaia, Brendan C. Visser, Andre Marziali, Bertram Wiedenmann, Jeffrey A. Norton, Mark Lee, Stefanie S. Jeffrey, and George A. Poultsides
|
| 2549-2561 |
|
| Fibroblast growth factor receptor 1 gene amplification is associated with poor survival in patients with resected esophageal squamous cell carcinoma |
|
https://doi.org/10.18632/oncotarget.2944
Hyo Song Kim, Seung Eun Lee, Yoon Sung Bae, Dae Joon Kim, Chang‑Geol Lee, Jin Hur, Hyunsoo Chung, Jun Chul Park, Da Hyun Jung, Sung Kwan Shin, Sang Kil Lee, Yong Chan Lee, Hye Ryun Kim, Yong Wha Moon, Joo Hang Kim, Young Mog Shim, Susan S. Jewell, Hyunki Kim, Yoon-La Choi, and Byoung Chul Cho
|
| 2562-2572 |
|
| Genetic polymorphisms in the vitamin D pathway in relation to lung cancer risk and survival |
|
https://doi.org/10.18632/oncotarget.2951
Jinyu Kong, Fangxiu Xu, Jinli Qu, Yu Wang, Ming Gao, Herbert Yu, and Biyun Qian
|
| 2573-2582 |