Vol 6, No 4

Hypoxia/HIF1α induces lapatinib resistance in ERBB2-positive breast cancer cells via regulation of DUSP2

Group I Paks as therapeutic targets in NF2-deficient meningioma

Neoalbaconol induces cell death through necroptosis by regulating RIPK-dependent autocrine TNFα and ROS production

Multiple receptor tyrosine kinase activation attenuates therapeutic efficacy of the fibroblast growth factor receptor 2 inhibitor AZD4547 in FGFR2 amplified gastric cancer

Sgo1 is a potential therapeutic target for hepatocellular carcinoma

Functional repair of p53 mutation in colorectal cancer cells using trans-splicing

Claudin-7 promotes the epithelial – mesenchymal transition in human colorectal cancer

Amyloid precursor-like protein 2 (APLP2) affects the actin cytoskeleton and increases pancreatic cancer growth and metastasis

Mesenchymal stem cells are resistant to carbon ion radiotherapy

mTOR kinase inhibitors synergize with histone deacetylase inhibitors to kill B-cell acute lymphoblastic leukemia cells

Silencing erythropoietin receptor on glioma cells reinforces efficacy of temozolomide and X-rays through senescence and mitotic catastrophe

TGF-β1 induces epigenetic silence of TIP30 to promote tumor metastasis in esophageal carcinoma

DNA damage induces GDNF secretion in the tumor microenvironment with paracrine effects promoting prostate cancer treatment resistance

Targeting a ribonucleoprotein complex containing the caprin-1 protein and the c-Myc mRNA suppresses tumor growth in mice: an identification of a novel oncotarget

Afatinib induces apoptosis in NSCLC without EGFR mutation through Elk-1-mediated suppression of CIP2A

γ-H2AX promotes hepatocellular carcinoma angiogenesis via EGFR/HIF-1α/VEGF pathways under hypoxic condition

DCLK1 is a broadly dysregulated target against epithelial-mesenchymal transition, focal adhesion, and stemness in clear cell renal carcinoma

Hypoxia up-regulates SERPINB3 through HIF-2α in human liver cancer cells

SKP2 cooperates with N-Ras or AKT to induce liver tumor development in mice

βIII-Tubulin: A novel mediator of chemoresistance and metastases in pancreatic cancer

Inhibition of HIF-1α by PX-478 enhances the anti-tumor effect of gemcitabine by inducing immunogenic cell death in pancreatic ductal adenocarcinoma

RUNX1, an androgen- and EZH2-regulated gene, has differential roles in AR-dependent and -independent prostate cancer

MicroRNA-26a promotes anoikis in human hepatocellular carcinoma cells by targeting alpha5 integrin

The antimicrobial peptide pardaxin exerts potent anti-tumor activity against canine perianal gland adenoma

Targeting the microRNA-21/AP1 axis by 5-fluorouracil and pirarubicin in human hepatocellular carcinoma

By promoting cell differentiation, miR-100 sensitizes basal-like breast cancer stem cells to hormonal therapy

Immunohistochemical quantification of the cobalamin transport protein, cell surface receptor and Ki-67 in naturally occurring canine and feline malignant tumors and in adjacent normal tissues

FOXM1 confers to epithelial-mesenchymal transition, stemness and chemoresistance in epithelial ovarian carcinoma cells

The tetraspanins CD151 and Tspan8 are essential exosome components for the crosstalk between cancer initiating cells and their surrounding

The anti-leukemic activity of sodium dichloroacetate in p53^mutated/null cells is mediated by a p53-independent ILF3/p21 pathway

The BRCA1/2-directed miRNA signature predicts a good prognosis in ovarian cancer patients with wild-type BRCA1/2

Resistance to everolimus driven by epigenetic regulation of MYC in ER+ breast cancers

MicroRNA-135b, a HSF1 target, promotes tumor invasion and metastasis by regulating RECK and EVI5 in hepatocellular carcinoma

Chloride channel-3 promotes tumor metastasis by regulating membrane ruffling and is associated with poor survival

Metabolic reprogramming of metastatic breast cancer and melanoma by let-7a microRNA

Genetic alterations of histone lysine methyltransferases and their significance in breast cancer

MicroRNA-500 sustains nuclear factor-κB activation and induces gastric cancer cell proliferation and resistance to apoptosis

Clinically relevant genes and regulatory pathways associated with NRAS^Q61 mutations in melanoma through an integrative genomics approach

Stabilization of LKB1 and Akt by neddylation regulates energy metabolism in liver cancer

Mutation of Vav1 adaptor region reveals a new oncogenic activation

Mutation profiling of tumor DNA from plasma and tumor tissue of colorectal cancer patients with a novel, high-sensitivity multiplexed mutation detection platform

Fibroblast growth factor receptor 1 gene amplification is associated with poor survival in patients with resected esophageal squamous cell carcinoma

Genetic polymorphisms in the vitamin D pathway in relation to lung cancer risk and survival