Oncotarget

Vol 9, No 37

May 15, 2018

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About The Cover

The cover for issue 37 of Oncotarget features Figure 5, "Synergy between ibrutinib or idelalisib and CSF1R inhibitors in majority of CLL patient specimens," from Edwards, et al.

Table of Contents

Editorial: Autophagy and Cell Death

The p53-p21 pathway inhibits ferroptosis during metabolic stress

The p53-p21 pathway inhibits ferroptosis during metabolic stress

https://doi.org/10.18632/oncotarget.25362

Amy Tarangelo,  and Scott Dixon
24572-24573
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Aspirin induces autophagy via inhibition of the acetyltransferase EP300

Aspirin induces autophagy via inhibition of the acetyltransferase EP300

https://doi.org/10.18632/oncotarget.25364

Francesca Castoldi, Federico Pietrocola, Maria Chiara Maiuri,  and Guido Kroemer
24574-24575
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Priority Research Papers

Targeting of colony-stimulating factor 1 receptor (CSF1R) in the CLL microenvironment yields antineoplastic activity in primary patient samples

Targeting of colony-stimulating factor 1 receptor (CSF1R) in the CLL microenvironment yields antineoplastic activity in primary patient samples

https://doi.org/10.18632/oncotarget.25191

David K. Edwards V, David Tyler Sweeney, Hibery Ho, Christopher A. Eide, Angela Rofelty, Anupriya Agarwal, Selina Qiuying Liu, Alexey V. Danilov, Patrice Lee, David Chantry, Shannon K. McWeeney, Brian J. Druker, Jeffrey W. Tyner, Stephen E. Spurgeon,  and Marc M. Loriaux
24576-24589
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Research Papers: Gerotarget (Focus on Aging)

Genome-wide significant risk factors on chromosome 19 and the APOE locus

Genome-wide significant risk factors on chromosome 19 and the APOE locus

https://doi.org/10.18632/oncotarget.25083

Sonia Moreno-Grau, Isabel Hernández, Stefanie Heilmann-Heimbach, Susana Ruiz, Maitée Rosende-Roca, Ana Mauleón, Liliana Vargas, Octavio Rodríguez-Gómez, Montserrat Alegret, Ana Espinosa, Gemma Ortega, Nuria Aguilera, Carla Abdelnour, Alzheimer’s Disease Neuroimaging Initiative, Silvia Gil, Wolfgang Maier, Oscar Sotolongo-Grau, Lluís Tárraga, Alfredo Ramirez, Jesús López-Arrrieta, Carmen Antúnez, Manuel Serrano- Ríos, Mercè Boada,  and Agustín Ruiz
24590-24600
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Research Papers

Olmesartan attenuates pressure-overload- or post-infarction-induced cardiac remodeling in mice

Olmesartan attenuates pressure-overload- or post-infarction-induced cardiac remodeling in mice

https://doi.org/10.18632/oncotarget.23628

Qiancheng Wang, Zhenhuan Chen, Xiaobo Huang, Lin Chen, Baihe Chen, Yingqi Zhu, Shiping Cao, Wangjun Liao, Jianping Bin, Masafumi Kitakaze,  and Yulin Liao
24601-24618
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Evaluation of liver fibrosis with a monoexponential model of intravoxel incoherent motion magnetic resonance imaging

Evaluation of liver fibrosis with a monoexponential model of intravoxel incoherent motion magnetic resonance imaging

https://doi.org/10.18632/oncotarget.24758

Cuiyun Chen, Fangfang Fu, Jing Zhang, Fangfang Guo, Meiyun Wang, Shaocheng Zhu, Dapeng Shi,  and Yuwei Tian
24619-24626
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Androgen-induced alterations in endometrial proteins crucial in recurrent miscarriages

Androgen-induced alterations in endometrial proteins crucial in recurrent miscarriages

https://doi.org/10.18632/oncotarget.24821

Tanzil Ur Rahman, Kamran Ullah, Meng-Xi Guo, Hai-Tao Pan, Juan Liu, Jun Ren, Lu-Yang Jin, Yu-Zhong Zhou, Yi Cheng, Jian-Zhong Sheng,  and He-Feng Huang
24627-24641
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Premorbid BMI as a prognostic factor in small-cell lung cancer—a single institute experience

Premorbid BMI as a prognostic factor in small-cell lung cancer—a single institute experience

https://doi.org/10.18632/oncotarget.24935

Cho-Hao Lee, Chin Lin, Chieh-Yung Wang, Tzu-Chuan Huang, Yi-Ying Wu, Wu-Chien Chien,  and Jia-Hong Chen
24642-24652
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Collagen type 1 promotes survival of human breast cancer cells by overexpressing Kv10.1 potassium and Orai1 calcium channels through DDR1-dependent pathway

Collagen type 1 promotes survival of human breast cancer cells by overexpressing Kv10.1 potassium and Orai1 calcium channels through DDR1-dependent pathway

https://doi.org/10.18632/oncotarget.19065

Mehdi Badaoui, Cloé Mimsy-Julienne, Charles Saby, Laurence Van Gulick, Marta Peretti, Pierre Jeannesson, Hamid Morjani,  and Halima Ouadid-Ahidouch
24653-24671
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Stability and anti-tumor effect of oncolytic herpes simplex virus type 2

Stability and anti-tumor effect of oncolytic herpes simplex virus type 2

https://doi.org/10.18632/oncotarget.25122

Yang Wang, Jing Jin, Zhen Wu, Sheng Hu, Han Hu, Zhifeng Ning, Yanfei Li, Yuting Dong, Jianwen Zou, Zeyong Mao, Xiaotai Shi, Huajun Zheng, Shuang Dong, Fuxing Liu, Zhizheng Fang, Jiliang Wu,  and Binlei Liu
24672-24683
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An integromic signature for lung cancer early detection

An integromic signature for lung cancer early detection

https://doi.org/10.18632/oncotarget.25227

Qixin Leng, Yanli Lin, Min Zhan,  and Feng Jiang
24684-24692
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Potentiation of 177Lu-octreotate peptide receptor radionuclide therapy of human neuroendocrine tumor cells by PARP inhibitor

Potentiation of 177Lu-octreotate peptide receptor radionuclide therapy of human neuroendocrine tumor cells by PARP inhibitor

https://doi.org/10.18632/oncotarget.25266

Nupur K. Purohit, Rashmi G. Shah, Samuel Adant, Michael Hoepfner, Girish M. Shah,  and Jean-Mathieu Beauregard
24693-24706
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Platinum sensitivity and DNA repair in a recently established panel of patient-derived ovarian carcinoma xenografts

Platinum sensitivity and DNA repair in a recently established panel of patient-derived ovarian carcinoma xenografts

https://doi.org/10.18632/oncotarget.25185

Federica Guffanti, Maddalena Fratelli, Monica Ganzinelli, Marco Bolis, Francesca Ricci, Francesca Bizzaro, Rosaria Chilà, Federica Paola Sina, Robert Fruscio, Michela Lupia, Ugo Cavallaro, Maria Rosa Cappelletti, Daniele Generali, Raffaella Giavazzi,  and Giovanna Damia
24707-24717
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Regulatory role of resveratrol, a microRNA-controlling compound, in HNRNPA1 expression, which is associated with poor prognosis in breast cancer

Regulatory role of resveratrol, a microRNA-controlling compound, in HNRNPA1 expression, which is associated with poor prognosis in breast cancer

https://doi.org/10.18632/oncotarget.25339

Kurataka Otsuka, Yusuke Yamamoto,  and Takahiro Ochiya
24718-24730
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Cirmtuzumab inhibits ibrutinib-resistant, Wnt5a-induced Rac1 activation and proliferation in mantle cell lymphoma

Cirmtuzumab inhibits ibrutinib-resistant, Wnt5a-induced Rac1 activation and proliferation in mantle cell lymphoma

https://doi.org/10.18632/oncotarget.25340

Jian Yu, Yun Chen, Liguang Chen, Ling Zhang, Laura Z. Rassenti, George F. Widhopf II,  and Thomas J. Kipps
24731-24736
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89Zr-labeled CEA-targeted IL-2 variant immunocytokine in patients with solid tumors: CEA-mediated tumor accumulation and role of IL-2 receptor-binding

89Zr-labeled CEA-targeted IL-2 variant immunocytokine in patients with solid tumors: CEA-mediated tumor accumulation and role of IL-2 receptor-binding

https://doi.org/10.18632/oncotarget.25343

Emilie M.J. van Brummelen, Marc C. Huisman, Linda J. de Wit-van der Veen, Tapan K. Nayak, Marcel P.M. Stokkel, Emma R. Mulder, Otto S. Hoekstra, Danielle J. Vugts, Guus A.M.S. Van Dongen, Henk M. Verheul, Stefan Evers, Jean J.L. Tessier, Jose Saro, Jan H.M. Schellens,  and C. Willemien Menke-van der Houven van Oordt
24737-24749
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Combined mTOR and MEK inhibition is an effective therapy in a novel mouse model for angiosarcoma

Combined mTOR and MEK inhibition is an effective therapy in a novel mouse model for angiosarcoma

https://doi.org/10.18632/oncotarget.25345

Michelle L. Chadwick, Adam Lane, Dana Thomas, Amanda R. Smith, Angela R. White, Dominique Davidson, Yuxin Feng, Elisa Boscolo, Yi Zheng, Denise M. Adams, Anita Gupta, André Veillette,  and Lionel M.L. Chow
24750-24765
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Mesenchymal stem cells enhance tumorigenic properties of human glioblastoma through independent cell-cell communication mechanisms

Mesenchymal stem cells enhance tumorigenic properties of human glioblastoma through independent cell-cell communication mechanisms

https://doi.org/10.18632/oncotarget.25346

Carolina Oliveira Rodini, Patrícia Benites Gonçalves da Silva, Amanda Faria Assoni, Valdemir Melechco Carvalho,  and Oswaldo Keith Okamoto
24766-24777
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Expression of P-REX2a is associated with poor prognosis in endometrial malignancies

Expression of P-REX2a is associated with poor prognosis in endometrial malignancies

https://doi.org/10.18632/oncotarget.25349

Sho Takeshita, Yoriko Yamashita, Kosuke Shiomi, Nako Suzuki, Jun Yoshida, Aya Naiki-Ito, Shugo Suzuki, Shinya Akatsuka, Shinya Toyokuni, Takashi Takahashi, Shoko Mase, Atsushi Arakawa, Mayumi Sugiura-Ogasawara,  and Satoru Takahashi
24778-24786
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Preclinical evaluation of novel fatty acid synthase inhibitors in primary colorectal cancer cells and a patient-derived xenograft model of colorectal cancer

Preclinical evaluation of novel fatty acid synthase inhibitors in primary colorectal cancer cells and a patient-derived xenograft model of colorectal cancer

https://doi.org/10.18632/oncotarget.25361

Yekaterina Y. Zaytseva, Piotr G. Rychahou, Anh-Thu Le, Timothy L. Scott, Robert M. Flight, Ji Tae Kim, Jennifer Harris, Jinpeng Liu, Chi Wang, Andrew J. Morris, Theru A. Sivakumaran, Teresa Fan, Hunter Moseley, Tianyan Gao, Eun Y. Lee, Heidi L. Weiss, Timothy S. Heuer, George Kemble,  and Mark Evers
24787-24800
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Meta-Analysis

Prognostic significance of immune cells in non-small cell lung cancer: meta-analysis

Prognostic significance of immune cells in non-small cell lung cancer: meta-analysis

https://doi.org/10.18632/oncotarget.24835

Ross A. Soo, Zhaojin Chen, Rebecca Siew Yan Teng, Hon-Lyn Tan, Barry Iacopetta, Bee Choo Tai,  and Richie Soong
24801-24820
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Prognostic value of Midkine expression in patients with solid tumors: a systematic review and meta-analysis

Prognostic value of Midkine expression in patients with solid tumors: a systematic review and meta-analysis

https://doi.org/10.18632/oncotarget.23892

Luo Zhang, Xing Song, Yingjie Shao, Changping Wu,  and Jingting Jiang
24821-24829
Abstract  |  PDF  |  HTML  |  Supplementary Information  |  Order a Reprint

Clinical Research Papers

A quality analysis of clinical anaesthesia study protocols from the Chinese clinical trials registry according to the SPIRIT statement

A quality analysis of clinical anaesthesia study protocols from the Chinese clinical trials registry according to the SPIRIT statement

https://doi.org/10.18632/oncotarget.24982

Lei Yang, Shouming Chen, Di Yang, Jiajin Li, Taixiang Wu,  and Yunxia Zuo
24830-24836
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Reviews

B-glucans from Grifola frondosa and Ganoderma lucidum in breast cancer: an example of complementary and integrative medicine

B-glucans from Grifola frondosa and Ganoderma lucidum in breast cancer: an example of complementary and integrative medicine

https://doi.org/10.18632/oncotarget.24984

Paola Rossi, Raffaele Difrancia, Vincenzo Quagliariello, Elena Savino, Paolo Tralongo, Cinzia Lucia Randazzo,  and Massimiliano Berretta
24837-24856
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Association of PDCD6 polymorphisms with the risk of cancer: Evidence from a meta-analysis

Association of PDCD6 polymorphisms with the risk of cancer: Evidence from a meta-analysis

https://doi.org/10.18632/oncotarget.25324

Mohammad Hashemi, Gholamreza Bahari, Jarosław Markowski, Andrzej Małecki, Marek J. Łos,  and Saeid Ghavami
24857-24868
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Corrections

Correction: Molecular crosstalk between ferroptosis and apoptosis: Emerging role of ER stress-induced p53-independent PUMA expression

Correction: Molecular crosstalk between ferroptosis and apoptosis: Emerging role of ER stress-induced p53-independent PUMA expression

https://doi.org/10.18632/oncotarget.25365

Se Hoon Hong, Dae-Hee Lee, Young-Sun Lee, Min Jee Jo, Yoon A. Jeong, William T. Kwon, Haroon A. Choudry, David L. Bartlett,  and Yong J. Lee
24869-24869
Correction  |  PDF

Correction: Berberine-targeted miR-21 chemosensitizes oral carcinomas stem cells

Correction: Berberine-targeted miR-21 chemosensitizes oral carcinomas stem cells

https://doi.org/10.18632/oncotarget.25460

Che-Yi Lin, Pei-Ling Hsieh, Yi-Wen Liao, Chih-Yu Peng, Ming-Yi Lu, Ching-Hsuan Yang, Cheng-Chia Yu,  and Chia-Ming Liu
24870-24870
Correction  |  PDF

Correction: MiR-124 acts as a target for Alzheimer’s disease by regulating BACE1

Correction: MiR-124 acts as a target for Alzheimer’s disease by regulating BACE1

https://doi.org/10.18632/oncotarget.25461

Fengmao An, Guohua Gong, Yu Wang, Ming Bian, Lijun Yu,  and Chengxi Wei
24871-24871
Correction  |  PDF


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