The Oncosearch | Oncotarget

Liposome encapsulated Disulfiram inhibits NFÎºB pathway and targets breast cancer stem cells in vitro and in vivo Research Paper

Peng Liu, Zhipeng Wang, Sarah Brown, Vinodh Kannappan, Patricia Erebi Tawari, Wenguo Jiang, Juan M. Irache, James Z. Tang, Stephen Britland, Angel L. Armesilla, John L. Darling, Weiguang Wang, Weiguang Wang Wang

Published Jul 4, 2014 · Vol. 5, No. 17 · pp. 7471-7485

Denosumab mimics the natural decoy receptor osteoprotegerin by interacting with its major binding site on RANKL Research Paper

Aneta Schieferdecker, Mareike Voigt, Kristoffer Riecken, Friederike Braig, Thorsten Schinke, Sonja Loges, Carsten Bokemeyer, Boris Fehse, Mascha Binder

Published Jul 3, 2014 · Vol. 5, No. 16 · pp. 6647-6653

PTK6/BRK is expressed in the normal mammary gland and activated at the plasma membrane in breast tumors Research Paper

Maoyu Peng, Rajyasree Emmadi, Zebin Wang, Elizabeth L. Wiley, Peter H. Gann, Seema A. Khan, Nilanjana Banerji, William McDonald, Szilard Asztalos, Thao N.D. Pham, Debra A. Tonetti, Angela L. Tyner

Published Jun 30, 2014 · Vol. 5, No. 15 · pp. 6038-6048

Targeted cytotoxic analog of luteinizing hormone-releasing hormone (LHRH), AEZS-108 (AN-152), inhibits the growth of DU-145 human castration-resistant prostate cancer in vivo and in vitro through elevating p21 and ROS levels Research Paper

Petra Popovics, Andrew V. Schally, Luca Szalontay, Norman L. Block, Ferenc G. Rick

Published Jun 29, 2014 · Vol. 5, No. 12 · pp. 4567-4578

Mer590, a novel monoclonal antibody targeting MER receptor tyrosine kinase, decreases colony formation and increases chemosensitivity in non-small cell lung cancer Research Paper

Christopher T. Cummings, Rachel M.A. Linger, Rebecca A. Cohen, Susan Sather, Gregory D. Kirkpatrick, Kurtis D. Davies, Deborah DeRyckere, H. Shelton Earp, Douglas K. Graham

Published Jun 26, 2014 · Vol. 5, No. 21 · pp. 10434-10445

Usp5 links suppression of p53 and FAS levels in melanoma to the BRAF pathway Research Paper

Harish Potu, Luke F. Peterson, Anupama Pal, Monique Verhaegen, Juxiang Cao, Moshe Talpaz, Nicholas J. Donato

Published Jun 26, 2014 · Vol. 5, No. 14 · pp. 5559-5569

Specific delivery of microRNA93 into HBV-replicating hepatocytes downregulates protein expression of liver cancer susceptible gene MICA Research Paper

Motoko Ohno, Motoyuki Otsuka, Takahiro Kishikawa, Chikako Shibata, Takeshi Yoshikawa, Akemi Takata, Ryosuke Muroyama, Norie Kowatari, Masaya Sato, Naoya Kato, Shun'ichi Kuroda, Kazuhiko Koike

Published Jun 26, 2014 · Vol. 5, No. 14 · pp. 5581-5590

A novel tumor suppressor function of Kindlin-3 in solid cancer Research Paper

Ibtissem Djaafri, Farah Khayati, Suzanne Menashi, Jorg Tost, Marie-Pierre Podgorniak, Aurelie Sadoux, Antoine Daunay, Luis Teixeira, Jean Soulier, Ahmed Idbaih, Niclas Setterblad, FranÃ§oise Fauvel, Fabien Calvo, Anne Janin, Celeste LebbÃ©, Samia Mourah

Published Jun 20, 2014 · Vol. 5, No. 19 · pp. 8970-8985

The anti-tumor activator sMEK1 and paclitaxel additively decrease expression of HIF-1Î± and VEGF via mTORC1-S6K/4E-BP-dependent signaling pathways Research Paper

Boh-Ram Kim, Kyungsil Yoon, Hyun-Jung Byun, Seung Hee Seo, Seung-Hoon Lee, Seung Bae Rho

Published Jun 19, 2014 · Vol. 5, No. 15 · pp. 6540-6551

Inhibition of glucose turnover by 3-bromopyruvate counteracts pancreatic cancer stem cell features and sensitizes cells to gemcitabine Research Paper

Orkhan Isayev, Vanessa Rausch, Nathalie Bauer, Li Liu, Pei Fan, Yiyao Zhang, Jury Gladkich, Clifford C. Nwaeburu, JÃ¼rgen Mattern, Martin Mollenhauer, Felix RÃ¼ckert, Sebastian Zach, Uwe Haberkorn, Wolfgang Gross, Frank SchÃ¶nsiegel, Alexandr V. Bazhin, Ingrid Herr

Published Jun 15, 2014 · Vol. 5, No. 13 · pp. 5177-5189

Functional genomics identifies novel genes essential for clear cell renal cell carcinoma tumor cell proliferation and migration Research Paper

Christina A. von Roemeling, Laura A. Marlow, Derek C. Radisky, Austin Rohl, Hege E. Larsen, Johnny Wei, Heather Sasinowska, Heng Zhu, Richard Drake, Maciek Sasinowski, Han W. Tun, John A. Copland

Published Jun 12, 2014 · Vol. 5, No. 14 · pp. 5320-5334

Synergistic induction of apoptosis by combination of BTK and dual mTORC1/2 inhibitors in diffuse large B cell lymphoma Research Paper

Scott A. Ezell, Michele Mayo, Teeru Bihani, Suprawee Tepsuporn, Suping Wang, Melissa Passino, Shaun E. Grosskurth, Mike Collins, Julie Parmentier, Corinne Reimer, Kate F. Byth

Published Jun 7, 2014 · Vol. 5, No. 13 · pp. 4990-5001

Engineered ubiquitin ligase PTB-U-box targets insulin/insulin-like growth factor receptor for degradation and coordinately inhibits cancer malignancy Research Paper

Qinhao Wang, Yi Ru, Daixing Zhong, Jing Zhang, Libo Yao, Xia Li

Published Jun 6, 2014 · Vol. 5, No. 13 · pp. 4945-4958

miR-942 decreases TRAIL-induced apoptosis through ISG12a downregulation and is regulated by AKT Research Paper

Nianli Liu, Chaohui Zuo, Xiaohong Wang, Tianran Chen, Darong Yang, Jing Wang, Haizhen Zhu

Published Jun 6, 2014 · Vol. 5, No. 13 · pp. 4959-4971

Identification of novel therapeutic targets in the PI3K/AKT/mTOR pathway in hepatocellular carcinoma using targeted next generation sequencing Research Paper

Filip Janku, Ahmed O. Kaseb, Apostolia M. Tsimberidou, Robert A. Wolff, Razelle Kurzrock

Published May 30, 2014 · Vol. 5, No. 10 · pp. 3012-3022

Keywords: hepatocellular carcinoma, PI3K, AKT, mTOR, next generation sequencing

GSK-3 as potential target for therapeutic intervention in cancer Review

James A. McCubrey, Linda S. Steelman, Fred E. Bertrand, Nicole M. Davis, Melissa Sokolosky, Steve L. Abrams, Giuseppe Montalto, Antonino B. Dâ€™Assoro, Massimo Libra, Ferdinando Nicoletti, Roberta Maestro, Jorg Basecke, Dariusz Rakus, Agnieszka Gizak, Zoya Demidenko, Lucio Cocco, Alberto M. Martelli, Melchiorre Cervello

Published May 28, 2014 · Vol. 5, No. 10 · pp. 2881-2911

20(S)-Ginsenoside Rg₃ is a novel inhibitor of autophagy and sensitizes hepatocellular carcinoma to doxorubicin Research Paper

Dong-Gun Kim, Kyung Hee Jung, Da-Gyum Lee, Jung-Ho Yoon, Kyeong Sook Choi, Sung Won Kwon, Han-Ming Shen, Michael J. Morgan, Soon-Sun Hong, You-Sun Kim

Published May 28, 2014 · Vol. 5, No. 12 · pp. 4438-4451

Phenotypic and genotypic characterization of azacitidine-sensitive and resistant SKM1 myeloid cell lines Research Paper

Thomas Cluzeau, Alix Dubois, Arnaud Jacquel, Frederic Luciano, Aline Renneville, Claude Preudhomme, Jean Michel Karsenti, Nicolas Mounier, Pierre Rohrlich, Sophie Raynaud, Bernard Mari, Guillaume Robert, Patrick Auberger

Published May 27, 2014 · Vol. 5, No. 12 · pp. 4384-4391

Selenocysteine derivative overcomes TRAIL resistance in melanoma cells: evidence for ROS-dependent synergism and signaling crosstalk Research Paper

Wenqiang Cao, Xiaoling Li, Shanyuan Zheng, Wenjie Zheng, Yum-shing Wong, Tianfeng Chen

Published May 26, 2014 · Vol. 5, No. 17 · pp. 7431-7445

Metformin limits the adipocyte tumor-promoting effect on ovarian cancer Research Paper

Calvin Tebbe, Jasdeep Chhina, Sajad A. Dar, Kalli Sarigiannis, Shailendra Giri, Adnan R. Munkarah, Ramandeep Rattan

Published May 26, 2014 · Vol. 5, No. 13 · pp. 4746-4764

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Liposome encapsulated Disulfiram inhibits NFÎºB pathway and targets breast cancer stem cells in vitro and in vivo Research Paper

Denosumab mimics the natural decoy receptor osteoprotegerin by interacting with its major binding site on RANKL Research Paper

PTK6/BRK is expressed in the normal mammary gland and activated at the plasma membrane in breast tumors Research Paper

Targeted cytotoxic analog of luteinizing hormone-releasing hormone (LHRH), AEZS-108 (AN-152), inhibits the growth of DU-145 human castration-resistant prostate cancer in vivo and in vitro through elevating p21 and ROS levels Research Paper

Mer590, a novel monoclonal antibody targeting MER receptor tyrosine kinase, decreases colony formation and increases chemosensitivity in non-small cell lung cancer Research Paper

Usp5 links suppression of p53 and FAS levels in melanoma to the BRAF pathway Research Paper

Specific delivery of microRNA93 into HBV-replicating hepatocytes downregulates protein expression of liver cancer susceptible gene MICA Research Paper

A novel tumor suppressor function of Kindlin-3 in solid cancer Research Paper

The anti-tumor activator sMEK1 and paclitaxel additively decrease expression of HIF-1Î± and VEGF via mTORC1-S6K/4E-BP-dependent signaling pathways Research Paper

Inhibition of glucose turnover by 3-bromopyruvate counteracts pancreatic cancer stem cell features and sensitizes cells to gemcitabine Research Paper

Functional genomics identifies novel genes essential for clear cell renal cell carcinoma tumor cell proliferation and migration Research Paper

Synergistic induction of apoptosis by combination of BTK and dual mTORC1/2 inhibitors in diffuse large B cell lymphoma Research Paper

Engineered ubiquitin ligase PTB-U-box targets insulin/insulin-like growth factor receptor for degradation and coordinately inhibits cancer malignancy Research Paper

miR-942 decreases TRAIL-induced apoptosis through ISG12a downregulation and is regulated by AKT Research Paper

Identification of novel therapeutic targets in the PI3K/AKT/mTOR pathway in hepatocellular carcinoma using targeted next generation sequencing Research Paper

GSK-3 as potential target for therapeutic intervention in cancer Review

20(S)-Ginsenoside Rg₃ is a novel inhibitor of autophagy and sensitizes hepatocellular carcinoma to doxorubicin Research Paper

Phenotypic and genotypic characterization of azacitidine-sensitive and resistant SKM1 myeloid cell lines Research Paper

Selenocysteine derivative overcomes TRAIL resistance in melanoma cells: evidence for ROS-dependent synergism and signaling crosstalk Research Paper

Metformin limits the adipocyte tumor-promoting effect on ovarian cancer Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Liposome encapsulated Disulfiram inhibits NFÎºB pathway and targets breast cancer stem cells in vitro and in vivo Research Paper

Denosumab mimics the natural decoy receptor osteoprotegerin by interacting with its major binding site on RANKL Research Paper

PTK6/BRK is expressed in the normal mammary gland and activated at the plasma membrane in breast tumors Research Paper

Targeted cytotoxic analog of luteinizing hormone-releasing hormone (LHRH), AEZS-108 (AN-152), inhibits the growth of DU-145 human castration-resistant prostate cancer in vivo and in vitro through elevating p21 and ROS levels Research Paper

Mer590, a novel monoclonal antibody targeting MER receptor tyrosine kinase, decreases colony formation and increases chemosensitivity in non-small cell lung cancer Research Paper

Usp5 links suppression of p53 and FAS levels in melanoma to the BRAF pathway Research Paper

Specific delivery of microRNA93 into HBV-replicating hepatocytes downregulates protein expression of liver cancer susceptible gene MICA Research Paper

A novel tumor suppressor function of Kindlin-3 in solid cancer Research Paper

The anti-tumor activator sMEK1 and paclitaxel additively decrease expression of HIF-1Î± and VEGF via mTORC1-S6K/4E-BP-dependent signaling pathways Research Paper

Inhibition of glucose turnover by 3-bromopyruvate counteracts pancreatic cancer stem cell features and sensitizes cells to gemcitabine Research Paper

Functional genomics identifies novel genes essential for clear cell renal cell carcinoma tumor cell proliferation and migration Research Paper

Synergistic induction of apoptosis by combination of BTK and dual mTORC1/2 inhibitors in diffuse large B cell lymphoma Research Paper

Engineered ubiquitin ligase PTB-U-box targets insulin/insulin-like growth factor receptor for degradation and coordinately inhibits cancer malignancy Research Paper

miR-942 decreases TRAIL-induced apoptosis through ISG12a downregulation and is regulated by AKT Research Paper

Identification of novel therapeutic targets in the PI3K/AKT/mTOR pathway in hepatocellular carcinoma using targeted next generation sequencing Research Paper

GSK-3 as potential target for therapeutic intervention in cancer Review

20(S)-Ginsenoside Rg3 is a novel inhibitor of autophagy and sensitizes hepatocellular carcinoma to doxorubicin Research Paper

Phenotypic and genotypic characterization of azacitidine-sensitive and resistant SKM1 myeloid cell lines Research Paper

Selenocysteine derivative overcomes TRAIL resistance in melanoma cells: evidence for ROS-dependent synergism and signaling crosstalk Research Paper

Metformin limits the adipocyte tumor-promoting effect on ovarian cancer Research Paper

20(S)-Ginsenoside Rg₃ is a novel inhibitor of autophagy and sensitizes hepatocellular carcinoma to doxorubicin Research Paper