The Oncosearch | Oncotarget

Endothelial integrin Î±3Î²1 stabilizes carbohydrate-mediated tumor/endothelial cell adhesion and induces macromolecular signaling complex formation at the endothelial cell membrane Research Paper

Olga V. Glinskii, Feng Li, Landon S. Wilson, Stephen Barnes, Kate Rittenhouse-Olson, Joseph J. Barchi Jr, Kenneth J. Pienta, Vladislav V. Glinsky

Published Mar 20, 2014 · Vol. 5, No. 5 · pp. 1382-1389

Targeted inhibition of cell-surface serine protease Hepsin blocks prostate cancer bone metastasis Research Paper

Xi Tang, Sumit S. Mahajan, Liem T. Nguyen, FranÃ§ois BÃ©liveau, Richard Leduc, Julian A. Simon, Valeri Vasioukhin

Published Mar 16, 2014 · Vol. 5, No. 5 · pp. 1352-1362

Endothelial Delta-like 4 (DLL4) promotes renal cell carcinoma hematogenous metastasis Research Paper

Qing Bo Huang, Xin Ma, Hong Zhao Li, Qing Ai, Shang Wen Liu, Yu Zhang, Yu Gao, Yang Fan, Dong Ni, Bao Jun Wang, Xu Zhang

Published Mar 14, 2014 · Vol. 5, No. 10 · pp. 3066-3075

Atg7- and Keap1-dependent autophagy protects breast cancer cell lines against mitoquinone-induced oxidative stress Research Paper

Yanira Gonzalez, Baikuntha Aryal, Leena Chehab, V Ashutosh Rao

Published Mar 12, 2014 · Vol. 5, No. 6 · pp. 1526-1537

Keywords: autophagy, reactive oxygen species, mitoquinone, breast cancer

MerTK inhibition is a novel therapeutic approach for glioblastoma multiforme Research Paper

Kristina H. Knubel, Ben M. Pernu, Alexandra Sufit, Sarah Nelson, Angela M. Pierce, Amy K. Keating

Published Mar 12, 2014 · Vol. 5, No. 5 · pp. 1338-1351

Linking differential radiation responses to glioma heterogeneity Research Paper

Chao Ke, Katherine Tran, Yumay Chen, Anne T. Di Donato, Liping Yu, Yuanjie Hu, Mark E. Linskey, Ping H. Wang, Charles L. Limoli, Yi-Hong Zhou

Published Mar 12, 2014 · Vol. 5, No. 6 · pp. 1657-1665

Necrosis-targeted combinational theragnostic approach to treat cancer Research Paper

Yun Ji, Xiaolong Hou, Cuihua Jiang, Wei Liu, Meng Gao, Yue Li, Junhun Wang, Qingqing Wang, Ziping Sun, Xiao Jiang, Nan Yao, Xiaoning Wang, Zhijun Fang, Zhiqi Yin, Jian Zhang, Yicheng Ni

Published Mar 11, 2014 · Vol. 5, No. 10 · pp. 2934-2946

Keywords: 131-iodine radioiodinated sennidin A (131I-SA), rodent tumor models, combretastatin A4 phosphate (CA4P), diagnosis, necrosis targeting radiotherapy

Linking off-target kinase pharmacology to the differential cellular effects observed among PARP inhibitors Research Paper

Albert A. AntolÃn, Jordi Mestres

Published Mar 10, 2014 · Vol. 5, No. 10 · pp. 3023-3028

Frequent L1 retrotranspositions originating from TTC28 in colorectal cancer Research Paper

Esa PitkÃ¤nen, Tatiana Cajuso, Riku Katainen, Eevi Kaasinen, Niko VÃ¤limÃ¤ki, Kimmo Palin, Jussi Taipale, Lauri A. Aaltonen, Outi Kilpivaara

Published Feb 14, 2014 · Vol. 5, No. 3 · pp. 853-859

Co-targeting the MAPK and PI3K/AKT/mTOR pathways in two genetically engineered mouse models of schwann cell tumors reduces tumor grade and multiplicity Research Paper

Adrienne L. Watson, Bryant J. Keller, Kyle A. Williams, Namrata N. Damle, Samuel J. Finnerty, Leah K. Anderson, Andrew D. Greeley, Vincent W. Keng, Eric P. Rahrmann, Amanda L. Halfond, Natasha M. Powell, Margaret H. Collins, Tilat Rizvi, Christopher L. Moertel, Nancy Ratner, David A. Largaespada

Published Jan 20, 2014 · Vol. 5, No. 6 · pp. 1502-1514

Keywords: Malignant peripheral nerve sheath tumors, plexiform neurofibromas, Schwann cells, neurofibromatosis type 1 syndrome, neurofibromin 1, PI3K/AKT/mTOR signaling, MAPK signaling, targeted therapies, genetically engineered mouse models, combination therapy

SCF^Î²-TRCP-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathway Research Paper

Jia Liu, Lixin Wan, Pengda Liu, Hiroyuki Inuzuka, Jiankang Liu, Zhiwei Wang, Wenyi Wei

Published Jan 20, 2014 · Vol. 5, No. 4 · pp. 1026-1037

Keywords: Î²-TRCP, NEDD4, degradation, PTEN, Akt, cancer, phosphorylation, ubiquitination, therapy

Immunogenicity of targeted lentivectors Research Paper

Cleo Goyvaerts, De Groeve Kurt, Sandra Van Lint, Carlo Heirman, Jo A. Van Ginderachter, Patrick De Baetselier, Geert Raes, Kris Thielemans, Karine Breckpot

Published Jan 19, 2014 · Vol. 5, No. 3 · pp. 704-715

Keywords: antitumor immunotherapy, lentiviral vectors, targeting, antigen-presenting cells

P-cadherin signals through the laminin receptor Î±6Î²4 integrin to induce stem cell and invasive properties in basal-like breast cancer cells Research Paper

AndrÃ© Filipe Vieira, Ana Sofia Ribeiro, Maria Rita DionÃsio, BÃ¡rbara Sousa, Ana Nobre, AndrÃ© Albergaria, AngÃ©lica Santiago-GÃ³mez, Nuno Mendes, RenÃª Gerhard, Fernando Schmitt, Robert Brian Clarke, Joana Paredes

Published Jan 6, 2014 · Vol. 5, No. 3 · pp. 679-692

Keywords: P-cadherin, Breast cancer, Î±6Î²4 integrin, cancer stem cells, invasion, FAK, Src

Survivin promoter-regulated oncolytic adenovirus with Hsp70 gene exerts effective antitumor efficacy in gastric cancer immunotherapy Research Paper

Weiguo Wang, Weidan Ji, Huanzhang Hu, Juming Ma, Xiaoya Li, Weiqun Mei, Yang Xu, Hui-Zhen Hu, Yan Yan, Qizhe Song, Zhigang Li, Changqing Su

Published Dec 28, 2013 · Vol. 5, No. 1 · pp. 150-160

Keywords: Gastric cancer, Survivin gene, Heat shock protein, Oncolytic adenovirus, Gene therapy

Thymoquinone overcomes chemoresistance and enhances the anticancer effects of bortezomib through abrogation of NF-ÎºB regulated gene products in multiple myeloma xenograft mouse model Research Paper

Kodappully Sivaraman Siveen, Nurulhuda Mustafa, Feng Li, Radhamani Kannaiyan, Kwang Seok Ahn, Alan Prem Kumar, Wee-Joo Chng, Gautam Sethi

Published Dec 18, 2013 · Vol. 5, No. 3 · pp. 634-648

Keywords: Thymoquinone, MM, bortezomib, apoptosis, NF-ÎºB

NF2/Merlin in hereditary neurofibromatosis 2 versus cancer: biologic mechanisms and clinical associations Review

Rebecca Dunbar Schroeder, Laura S. Angelo, Razelle Kurzrock

Published Dec 17, 2013 · Vol. 5, No. 1 · pp. 67-77

Keywords: NF2, Nuerofibromatosis 2, Cancer, Mutations

ERG induces a mesenchymal-like state associated with chemoresistance in leukemia cells Research Paper

Liliana H. Mochmann, Martin Neumann, Eva K. von Der Heide, Verena Nowak, Anja A. KÃ¼hl, Jutta Ortiz-Tanchez, Juliane Bock, Wolf K Hofmann, Claudia D Baldus

Published Dec 4, 2013 · Vol. 5, No. 2 · pp. 351-362

Keywords: ERG, ERK, EMT, Chemoresistance

Genome-wide methylation patterns provide insight into differences in breast tumor biology between American women of African and European ancestry Research Paper

Christine B. Ambrosone, Allyson C. Young, Lara E. Sucheston, Dan Wang, Li Yan, Song Liu, Li Tang, Qiang Hu, Jo L. Freudenheim, Peter G. Shields, Carl D. Morrison, Kitaw Demissie, Michael J. Higgins

Published Nov 29, 2013 · Vol. 5, No. 1 · pp. 237-248

Keywords: DNA methylation, breast cancer, disparities, estrogen receptor, African-American, genome-wide

The proto-oncogene KRAS is targeted by miR-200c Research Paper

Florian Kopp, Ernst Wagner, Andreas Roidl

Published Nov 24, 2013 · Vol. 5, No. 1 · pp. 185-195

Keywords: breast cancer, lung cancer, miRNA, K-ras, cell cycle, proliferation

In situ mutation detection and visualization of intratumor heterogeneity for cancer research and diagnostics Research Paper

Ida Grundberg, Sara Kiflemariam, Marco Mignardi, Juliana Imgenberg-Kreuz, Karolina Edlund, Patrick Micke, Magnus SundstrÃ¶m, Tobias SjÃ¶blom, Johan Botling, Mats Nilsson

Published Nov 21, 2013 · Vol. 4, No. 12 · pp. 2407-2418

Keywords: Padlock probes, RCA, in situ, KRAS, cancer diagnostics

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Endothelial integrin Î±3Î²1 stabilizes carbohydrate-mediated tumor/endothelial cell adhesion and induces macromolecular signaling complex formation at the endothelial cell membrane Research Paper

Targeted inhibition of cell-surface serine protease Hepsin blocks prostate cancer bone metastasis Research Paper

Endothelial Delta-like 4 (DLL4) promotes renal cell carcinoma hematogenous metastasis Research Paper

Atg7- and Keap1-dependent autophagy protects breast cancer cell lines against mitoquinone-induced oxidative stress Research Paper

MerTK inhibition is a novel therapeutic approach for glioblastoma multiforme Research Paper

Linking differential radiation responses to glioma heterogeneity Research Paper

Necrosis-targeted combinational theragnostic approach to treat cancer Research Paper

Linking off-target kinase pharmacology to the differential cellular effects observed among PARP inhibitors Research Paper

Frequent L1 retrotranspositions originating from TTC28 in colorectal cancer Research Paper

Co-targeting the MAPK and PI3K/AKT/mTOR pathways in two genetically engineered mouse models of schwann cell tumors reduces tumor grade and multiplicity Research Paper

SCF^Î²-TRCP-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathway Research Paper

Immunogenicity of targeted lentivectors Research Paper

P-cadherin signals through the laminin receptor Î±6Î²4 integrin to induce stem cell and invasive properties in basal-like breast cancer cells Research Paper

Survivin promoter-regulated oncolytic adenovirus with Hsp70 gene exerts effective antitumor efficacy in gastric cancer immunotherapy Research Paper

Thymoquinone overcomes chemoresistance and enhances the anticancer effects of bortezomib through abrogation of NF-ÎºB regulated gene products in multiple myeloma xenograft mouse model Research Paper

NF2/Merlin in hereditary neurofibromatosis 2 versus cancer: biologic mechanisms and clinical associations Review

ERG induces a mesenchymal-like state associated with chemoresistance in leukemia cells Research Paper

Genome-wide methylation patterns provide insight into differences in breast tumor biology between American women of African and European ancestry Research Paper

The proto-oncogene KRAS is targeted by miR-200c Research Paper

In situ mutation detection and visualization of intratumor heterogeneity for cancer research and diagnostics Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Endothelial integrin Î±3Î²1 stabilizes carbohydrate-mediated tumor/endothelial cell adhesion and induces macromolecular signaling complex formation at the endothelial cell membrane Research Paper

Targeted inhibition of cell-surface serine protease Hepsin blocks prostate cancer bone metastasis Research Paper

Endothelial Delta-like 4 (DLL4) promotes renal cell carcinoma hematogenous metastasis Research Paper

Atg7- and Keap1-dependent autophagy protects breast cancer cell lines against mitoquinone-induced oxidative stress Research Paper

MerTK inhibition is a novel therapeutic approach for glioblastoma multiforme Research Paper

Linking differential radiation responses to glioma heterogeneity Research Paper

Necrosis-targeted combinational theragnostic approach to treat cancer Research Paper

Linking off-target kinase pharmacology to the differential cellular effects observed among PARP inhibitors Research Paper

Frequent L1 retrotranspositions originating from TTC28 in colorectal cancer Research Paper

Co-targeting the MAPK and PI3K/AKT/mTOR pathways in two genetically engineered mouse models of schwann cell tumors reduces tumor grade and multiplicity Research Paper

SCFÎ²-TRCP-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathway Research Paper

Immunogenicity of targeted lentivectors Research Paper

P-cadherin signals through the laminin receptor Î±6Î²4 integrin to induce stem cell and invasive properties in basal-like breast cancer cells Research Paper

Survivin promoter-regulated oncolytic adenovirus with Hsp70 gene exerts effective antitumor efficacy in gastric cancer immunotherapy Research Paper

Thymoquinone overcomes chemoresistance and enhances the anticancer effects of bortezomib through abrogation of NF-ÎºB regulated gene products in multiple myeloma xenograft mouse model Research Paper

NF2/Merlin in hereditary neurofibromatosis 2 versus cancer: biologic mechanisms and clinical associations Review

ERG induces a mesenchymal-like state associated with chemoresistance in leukemia cells Research Paper

Genome-wide methylation patterns provide insight into differences in breast tumor biology between American women of African and European ancestry Research Paper

The proto-oncogene KRAS is targeted by miR-200c Research Paper

In situ mutation detection and visualization of intratumor heterogeneity for cancer research and diagnostics Research Paper

SCF^Î²-TRCP-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathway Research Paper