The Oncosearch | Oncotarget

Failure of anti tumor-derived endothelial cell immunotherapy depends on augmentation of tumor hypoxia Research Paper

Annalisa Pezzolo, Danilo Marimpietri, Lizzia Raffaghello, Claudia Cocco, Angela Pistorio, Claudio Gambini, Michele Cilli, Alberto Horenstein, Fabio Malavasi, Vito Pistoia

Published May 26, 2014 · Vol. 5, No. 21 · pp. 10368-10381

Characteristics and survival of patients with advanced cancer and p53 mutations Research Paper

Rabih Said, Yang Ye, David S. Hong, Filip Janku, Siqing Fu, Aung Naing, Jennifer J. Wheler, Razelle Kurzrock, Christoforos Thomas, Gary A. Palmer, Kenneth R. Hess, Kenneth Aldape, Apostolia M. Tsimberidou

Published May 25, 2014 · Vol. 5, No. 11 · pp. 3871-3879

HGF/MET-directed therapeutics in gastroesophageal cancer: a review of clinical and biomarker development Review

Stephen P. Hack, Jean-Marie Bruey, Hartmut Koeppen

Published May 24, 2014 · Vol. 5, No. 10 · pp. 2866-2880

Sox9 mediates Notch1-induced mesenchymal features in lung adenocarcinoma Research Paper

Kathleen M. Capaccione, Xuehui Hong, Katherine M. Morgan, Wenyu Liu, Michael J. Bishop, LianXin Liu, Elke Markert, Malik Deen, Christine Minerowicz, Thaddeus Allen, Sharon R. Pine

Published May 19, 2014 · Vol. 5, No. 11 · pp. 3636-3650

Melanoma cell therapy: Endothelial progenitor cells as shuttle of the MMP12 uPAR-degrading enzyme Research Paper

Anna Laurenzana, Alessio Biagioni, Silvia Dâ€™Alessio, Francesca Bianchini, Anastasia ChillÃ, Francesca Margheri, Cristina Luciani, Benedetta Mazzanti, Nicola Pimpinelli, Eugenio Torre, Silvio Danese, Lido Calorini, Mario Del Rosso, Gabriella Fibbi

Published May 19, 2014 · Vol. 5, No. 11 · pp. 3711-3727

ROS-mediated EB1 phosphorylation through Akt/GSK3Î² pathway: implication in cancer cell response to microtubule-targeting agents Research Paper

Marion Le Grand, Amandine Rovini, Veronique Bourgarel-Rey, Stephane Honore, Sonia Bastonero, Diane Braguer, Manon Carre

Published May 18, 2014 · Vol. 5, No. 10 · pp. 3408-3423

The targeting mechanism of DHA ligand and its conjugate with Gemcitabine for the enhanced tumor therapy Research Paper

Siwen Li, Jingyi Qin, Caiping Tian, Jie Cao, Guissi Fida, Zhaohui Wang, Haiyan Chen, Zhiyu Qian, Wei R. Chen, Yueqing Gu

Published May 13, 2014 · Vol. 5, No. 11 · pp. 3622-3635

Combination of PIM and JAK2 inhibitors synergistically suppresses cell proliferation and overcomes drug resistance of myeloproliferative neoplasms Research Paper

Shih-Min A. Huang, Anlai Wang, Rita Greco, Zhifang Li, Claude Barberis, Michel Tabart, Vinod Patel, Laurent Schio, Raelene Hurley, Hong Cheng, Christoph Lengauer, Jack Pollard, James Watters, Carlos Garcia-Echeverria, Dmitri Wiederschain, Francisco Adrian, JingXin Zhang

Published May 8, 2014 · Vol. 5, No. 10 · pp. 3362-3374

Tumor cell-produced matrix metalloproteinase 9 (MMP-9) drives malignant progression and metastasis of basal-like triple negative breast cancer Research Paper

Christine Mehner, Alexandra Hockla, Erin Miller, Sophia Ran, Derek C. Radisky, Evette S. Radisky

Published May 1, 2014 · Vol. 5, No. 9 · pp. 2736-2749

The IGF-1 receptor inhibitor picropodophyllin potentiates the anti-myeloma activity of a BH3-mimetic Research Paper

Liesbeth Bieghs, Susanne Lub, Karel Fostier, Ken Maes, Els Van Valckenborgh, Eline Menu, Hans E. Johnsen, Michael T. Overgaard, Olle Larsson, Magnus Axelson, Mette Nyegaard, Rik Schots, Helena Jernberg-Wiklund, Karin Vanderkerken, Elke De Bruyne

Published Apr 30, 2014 · Vol. 5, No. 22 · pp. 11193-11208

Targeting human apurinic/apyrimidinic endonuclease 1 (APE1) in phosphatase and tensin homolog (PTEN) deficient melanoma cells for personalized therapy Research Paper

Rachel Abbotts, Rosalyn Jewell, JÃ©rÃ©mie Nsengimana, David J. Maloney, Anton Simeonov, Claire Seedhouse, Faye Elliott, Jon Laye, Christy Walker, Ajit Jadhav, Anna Grabowska, Graham Ball, Poulam M. Patel, Julia Newton-Bishop, David M. Wilson III, Srinivasan Madhusudan

Published Apr 27, 2014 · Vol. 5, No. 10 · pp. 3273-3286

MDM2 antagonists synergize broadly and robustly with compounds targeting fundamental oncogenic signaling pathways Priority Research Paper

Anne Y. Saiki, Sean Caenepeel, Dongyin Yu, Julie A. Lofgren, Tao Osgood, Rebecca Robertson, Jude Canon, Cheng Su, Adrie Jones, Xiaoning Zhao, Chetan Deshpande, Marc Payton, Jebediah Ledell, Paul E. Hughes, Jonathan D. Oliner

Published Apr 23, 2014 · Vol. 5, No. 8 · pp. 2030-2043

Caspase-3 and Caspase-6 cleave STAT1 in leukemic cells Research Paper

Verena Licht, Katrin Noack, Bernhard Schlott, Martin FÃ¶rster, Yvonne Schlenker, Andreas Licht, Oliver H. KrÃ¤mer, Thorsten Heinzel

Published Apr 18, 2014 · Vol. 5, No. 8 · pp. 2305-2317

Molecular pathways and therapeutic targets in lung cancer Review

Emma Shtivelman, Thomas Hensing, George R. Simon, Phillip A. Dennis, Gregory A. Otterson, Raphael Bueno, Ravi Salgia

Published Apr 8, 2014 · Vol. 5, No. 6 · pp. 1392-1433

Pathways and therapeutic targets in melanoma Review

Emma Shtivelman, Michael A. Davies, Patrick Hwu, James Yang, Michal Lotem, Moshe Oren, Keith T. Flaherty, David E. Fisher

Published Apr 8, 2014 · Vol. 5, No. 7 · pp. 1701-1752

Inhibition of BRD4 attenuates tumor cell self-renewal and suppresses stem cell signaling in MYC driven medulloblastoma Research Paper

Sujatha Venataraman, Irina Alimova, Peter Harris, Diane K Birks, Illango Balakrishnan, Marc Remke, Michael D Taylor, Michael Handler, Nicholas K Foreman, Rajeev Vibhakar

Published Mar 31, 2014 · Vol. 5, No. 9 · pp. 2355-2371

Keywords: Medulloblastoma, Myc, BRD4, JQ1, Senescence

Therapeutic Targeting of c-Myc in T-Cell Acute Lymphoblastic Leukemia (T-ALL) Research Paper

Marie Loosveld, RÃ©my Castellano, StÃ©phanie Gon, Armelle Goubard, Thomas Crouzet, Laurent Pouyet, Thomas Prebet, Norbert Vey, Bertrand Nadel, Yves Collette, Dominique Payet-Bornet

Published Mar 27, 2014 · Vol. 5, No. 10 · pp. 3168-3172

SPHK1 regulates proliferation and survival responses in triple-negative breast cancer Research Paper

Arpita Datta, Ser Yue Loo, Baohua Huang, Lingkai Wong, Sheryl S.L. Tan, Tuan Zea Tan, Soo-Chin Lee, Jean Paul Thiery, Yaw Chyn Lim, Wei Peng Yong, Yulin Lam, Alan Prem Kumar, Celestial T. Yap

Published Mar 27, 2014 · Vol. 5, No. 15 · pp. 5920-5933

Kinome profiling reveals breast cancer heterogeneity and identifies targeted therapeutic opportunities for triple negative breast cancer Research Paper

Fares Al-Ejeh, Mariska Miranda, Wei Shi, Peter T. Simpson, Sarah Song, Ana Cristina Vargas, Jodi M. Saunus, Chanel E. Smart, Mythily Mariasegaram, Adrian P. Wiegmans, Georgia Chenevix-Trench, Sunil R. Lakhani, Kum Kum Khanna

Published Mar 26, 2014 · Vol. 5, No. 10 · pp. 3145-3158

The immunocytokine NHS-IL12 as a potential cancer therapeutic Research Paper

Jonathan Fallon, Robert Tighe, Giorgio Kradjian, Wilson Guzman, Anna Bernhardt, Berend Neuteboom, Yan Lan, Helen Sabzevari, Jeffrey Schlom, John W. Greiner

Published Mar 24, 2014 · Vol. 5, No. 7 · pp. 1869-1884

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Failure of anti tumor-derived endothelial cell immunotherapy depends on augmentation of tumor hypoxia Research Paper

Characteristics and survival of patients with advanced cancer and p53 mutations Research Paper

HGF/MET-directed therapeutics in gastroesophageal cancer: a review of clinical and biomarker development Review

Sox9 mediates Notch1-induced mesenchymal features in lung adenocarcinoma Research Paper

Melanoma cell therapy: Endothelial progenitor cells as shuttle of the MMP12 uPAR-degrading enzyme Research Paper

ROS-mediated EB1 phosphorylation through Akt/GSK3Î² pathway: implication in cancer cell response to microtubule-targeting agents Research Paper

The targeting mechanism of DHA ligand and its conjugate with Gemcitabine for the enhanced tumor therapy Research Paper

Combination of PIM and JAK2 inhibitors synergistically suppresses cell proliferation and overcomes drug resistance of myeloproliferative neoplasms Research Paper

Tumor cell-produced matrix metalloproteinase 9 (MMP-9) drives malignant progression and metastasis of basal-like triple negative breast cancer Research Paper

The IGF-1 receptor inhibitor picropodophyllin potentiates the anti-myeloma activity of a BH3-mimetic Research Paper

Targeting human apurinic/apyrimidinic endonuclease 1 (APE1) in phosphatase and tensin homolog (PTEN) deficient melanoma cells for personalized therapy Research Paper

MDM2 antagonists synergize broadly and robustly with compounds targeting fundamental oncogenic signaling pathways Priority Research Paper

Caspase-3 and Caspase-6 cleave STAT1 in leukemic cells Research Paper

Molecular pathways and therapeutic targets in lung cancer Review

Pathways and therapeutic targets in melanoma Review

Inhibition of BRD4 attenuates tumor cell self-renewal and suppresses stem cell signaling in MYC driven medulloblastoma Research Paper

Therapeutic Targeting of c-Myc in T-Cell Acute Lymphoblastic Leukemia (T-ALL) Research Paper

SPHK1 regulates proliferation and survival responses in triple-negative breast cancer Research Paper

Kinome profiling reveals breast cancer heterogeneity and identifies targeted therapeutic opportunities for triple negative breast cancer Research Paper

The immunocytokine NHS-IL12 as a potential cancer therapeutic Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Failure of anti tumor-derived endothelial cell immunotherapy depends on augmentation of tumor hypoxia Research Paper

Characteristics and survival of patients with advanced cancer and p53 mutations Research Paper

HGF/MET-directed therapeutics in gastroesophageal cancer: a review of clinical and biomarker development Review

Sox9 mediates Notch1-induced mesenchymal features in lung adenocarcinoma Research Paper

Melanoma cell therapy: Endothelial progenitor cells as shuttle of the MMP12 uPAR-degrading enzyme Research Paper

ROS-mediated EB1 phosphorylation through Akt/GSK3Î² pathway: implication in cancer cell response to microtubule-targeting agents Research Paper

The targeting mechanism of DHA ligand and its conjugate with Gemcitabine for the enhanced tumor therapy Research Paper

Combination of PIM and JAK2 inhibitors synergistically suppresses cell proliferation and overcomes drug resistance of myeloproliferative neoplasms Research Paper

Tumor cell-produced matrix metalloproteinase 9 (MMP-9) drives malignant progression and metastasis of basal-like triple negative breast cancer Research Paper

The IGF-1 receptor inhibitor picropodophyllin potentiates the anti-myeloma activity of a BH3-mimetic Research Paper

Targeting human apurinic/apyrimidinic endonuclease 1 (APE1) in phosphatase and tensin homolog (PTEN) deficient melanoma cells for personalized therapy Research Paper

MDM2 antagonists synergize broadly and robustly with compounds targeting fundamental oncogenic signaling pathways Priority Research Paper

Caspase-3 and Caspase-6 cleave STAT1 in leukemic cells Research Paper

Molecular pathways and therapeutic targets in lung cancer Review

Pathways and therapeutic targets in melanoma Review

Inhibition of BRD4 attenuates tumor cell self-renewal and suppresses stem cell signaling in MYC driven medulloblastoma Research Paper

Therapeutic Targeting of c-Myc in T-Cell Acute Lymphoblastic Leukemia (T-ALL) Research Paper

SPHK1 regulates proliferation and survival responses in triple-negative breast cancer Research Paper

Kinome profiling reveals breast cancer heterogeneity and identifies targeted therapeutic opportunities for triple negative breast cancer Research Paper

The immunocytokine NHS-IL12 as a potential cancer therapeutic Research Paper