The Oncosearch | Oncotarget

Blockade of the PDGFR family together with SRC leads to diminished proliferation of colorectal cancer cells Research Paper

Silke KaulfuÃŸ, Henning Seemann, Rovena Kampe, Julia Meyer, Ralf Dressel, Britta KÃ¶nig, Jens-Gerd Scharf, Peter Burfeind

Published Jun 30, 2013 · Vol. 4, No. 7 · pp. 1037-1049

Keywords: colorectal cancer, PDGF receptor, c-KIT, SRC, cell proliferation, apoptosis, RNA interference, targeted therapy

Plasma Membrane Proteomics Identifies Biomarkers Associated with MMSET Overexpression in T(4;14) Multiple Myeloma Research Paper

Zhigang Xie, Jayantha Gunaratne, Lip Lee Cheong, Shaw Cheng Liu, Tze Loong Koh, Gaofeng Huang, Walter P Blackstock, Wee Joo Chng

Published Jun 26, 2013 · Vol. 4, No. 7 · pp. 1008-1018

Keywords: SILAC, quantitative proteomics, oncotargets, multiple myeloma

Thymoma Patients Treated in a Phase I Clinic at MD Anderson Cancer Center: Responses to mTOR Inhibitors and Molecular Analyses Research Paper

Jennifer J. Wheler, David Hong, Stephen G. Swisher, Gerald S. Falchook, Apostolia Maria Tsimberidou, Thorunn Helgason, Aung Naing, Bettzy Stephen, Filip Janku, Philip J. Stephens, Roman Yelensky, Razelle Kurzrock

Published Jun 10, 2013 · Vol. 4, No. 6 · pp. 890-898

Keywords: advanced thymoma, mTOR inhibitors, targeted therapy, thymic carcinoma

Powerful Inhibition of Experimental Human Pancreatic Cancers by Receptor Targeted Cytotoxic LH-RH analog AEZS-108 Research Paper

Karoly Szepeshazi, Andrew V. Schally, Norman L. Block, Gabor Halmos, Mehrdad Nadji, Luca Szalontay, Irving Vidaurre, Andrew Abi-Chaker, Ferenc G. Rick

Published Jun 3, 2013 · Vol. 4, No. 5 · pp. 751-760

Keywords: pancreatic carcinoma, targeted therapy, LH-RH receptor, cytotoxic LHRH analog, GnRH, doxorubicin, peptide therapy

Cross-species genomic and epigenomic landscape of retinoblastoma Research Paper

Claudia A. Benavente, Justina D. McEvoy, David Finkelstein, Lei Wei, Guolian Kang, Yong-Dong Wang, Geoffrey Neale, Susan Ragsdale, Virginia Valentine, Armita Bahrami, Jamshid Temirov, Stanley Pounds, Jinghui Zhang, Michael A. Dyer

Published Jun 1, 2013 · Vol. 4, No. 6 · pp. 844-859

Keywords: retinoblastoma, RB1, epigenetics

To grab the stroma by the horns: From biology to cancer therapy with mesenchymal stem cells Review

Ilia A. Droujinine, Mark A Eckert, Weian Zhao

Published May 31, 2013 · Vol. 4, No. 5 · pp. 651-664

Keywords: mesenchymal stem cells, cell therapy, stroma, microenvironment, tumor associated fibroblasts

FAM83B-mediated activation of PI3K/AKT and MAPK signaling cooperates to promote epithelial cell transformation and resistance to targeted therapies. Research Paper

Rocky Cipriano, Kristy L.S. Miskimen, Benjamin L. Bryson, Chase R. Foy, Courtney A. Bartel, Mark W Jackson

Published May 11, 2013 · Vol. 4, No. 5 · pp. 729-738

Keywords: FAM83B, transformation, drug resistance, CRAF, PI3K

P53 Mutations in Advanced Cancers: Clinical Characteristics, Outcomes, and Correlation between Progression-Free Survival and Bevacizumab-Containing Therapy Research Paper

Rabih Said, David S. Hong, Carla L. Warneke, J. Jack Lee, Jennifer J. Wheler, Filip Janku, Aung Naing, Gerald S. Falchook, Siqing Fu, Sarina Piha-Paul, Apostolia M. Tsimberidou, Razelle Kurzrock

Published May 1, 2013 · Vol. 4, No. 5 · pp. 705-714

Keywords: P53 mutations, PTEN loss, bevacizumab, Li-Fraumeni syndrome

Combinatorial drug screening identifies compensatory pathway interactions and adaptive resistance mechanisms Research Paper

Mark J Axelrod, Vicki Gordon, Mark Conaway, Adel Tarcsafalvi, Daniel J Neitzke, Daniel Gioeli, Michael J Weber

Published Apr 10, 2013 · Vol. 4, No. 4 · pp. 622-635

Keywords: Targeted therapies, Compensatory signaling, Pathway interactions, Crosstalk, Feedback inhibition

Effects of CT-Xp Gene Knock down in Melanoma Cell Lines Research Paper

Otavia Luisa Caballero, Tzeela Cohen, Sita Gurung, Ramon Chua, Peishan Lee, Yao-Tseng Chen, Parmjit Jat, Lloyd J. Old, Andrew J. G. Simpson

Published Mar 27, 2013 · Vol. 4, No. 4 · pp. 531-541

Keywords: Cancer/testis genes, GAGE, XAGE1, SSX, siRNA, melanoma

Linked-In: Design and Efficacy of Antibody Drug Conjugates in Oncology Review

Jonathan Feld, Stefan K. Barta, Carolina Schinke, Ira Braunschweig, Yiyu Zhou, Amit K. Verma

Published Mar 26, 2013 · Vol. 4, No. 3 · pp. 397-412

Keywords: antibody drug conjugates, oncotargets, immunotoxins

Drug-Loaded Nanoparticle Systems And Adult Stem Cells: A Potential Marriage For The Treatment Of Malignant Glioma? Review

Brenda Auffinger, Ramin Morshed, Alex Tobias, Yu Cheng, Atique U Ahmed, Maciej S Lesniak

Published Mar 26, 2013 · Vol. 4, No. 3 · pp. 378-396

Keywords: Nanoparticle, drug delivery systems, stem cell carriers, malignant glioma, brain cancer, targeted delivery

Inhibition of U-87 MG glioblastoma by AN-152 (AEZS-108), a targeted cytotoxic analog of luteinizing hormone-releasing hormone Research Paper

Miklos Jaszberenyi, Andrew V Schally, Norman L Block, Mehrdad Nadji, Irving Vidaurre, Luca Szalontay, Ferenc G Rick

Published Mar 7, 2013 · Vol. 4, No. 3 · pp. 422-432

Keywords: glioblastoma multiforme, U-87 MG, cytotoxic, LHRHor GnRH receptors, AN-152, AEZS-108, nude mice, targeted therapy

Luteolin is a novel p90 ribosomal S6 kinase (RSK) inhibitor that suppresses Notch4 signaling by blocking the activation of Y-box binding protein-1 (YB-1) Research Paper

Kristen M. Reipas, Jennifer H. Law, Nicole Couto, Sumaiya Islam, Yvonne Li, Huifang Li, Artem Cherkasov, Karen Jung, Amarpal S. Cheema, Steven J.M. Jones, John A. Hassell, Sandra E. Dunn

Published Feb 27, 2013 · Vol. 4, No. 2 · pp. 329-345

Keywords: Triple-negative breast cancer, p90 ribosomal S6 kinase, Y-box binding protein-1, tumor-initiating cells, drug repositioning

Efemp1 and p27Kip1 modulate responsiveness of pancreatic cancer cells towards a dual PI3K/mTOR inhibitor in preclinical models Research Paper

Diersch Sandra, Patrick Wenzel, Melanie Szameitat, Philipp Eser, Mariel C Paul, Barbara Seidler, Stefan Eser, Marlena Messer, Maximilian Reichert, Philipp Pagel, Irene Esposito, Roland M Schmid, Dieter Saur, GÃ¼nter Schneider

Published Feb 26, 2013 · Vol. 4, No. 2 · pp. 277-288

Keywords: pancreatic cancer, PI3K, Efemp1, p27, Bez235

Targeted alpha-therapy using [Bi-213]anti-CD20 as novel treatment option for radio- and chemoresistant non-Hodgkin lymphoma cells Research Paper

Mareike Roscher, Inis Hormann, Oliver Leib, Sebastian Marx, Josue Moreno, Erich Miltner, Claudia Friesen

Published Feb 24, 2013 · Vol. 4, No. 2 · pp. 218-230

Keywords: non-Hodgkin lymphoma, targeted alpha-therapy, anti-CD20, Bismuth-213, radioresistance, apoptosis

TRAIL induces apoptosis in oral squamous carcinoma cells: a crosstalk with oncogenic Ras regulated cell surface expression of death receptor 5 Research Paper

Jun-jie Chen, Constantinos M. Mikelis, Yaqin Zhang, J. Silvio Gutkind, Baolin Zhang

Published Feb 23, 2013 · Vol. 4, No. 2 · pp. 206-217

Keywords: oral cancer, TRAIL, death receptors, apoptosis, Ras, oncotarget

Calcein-effluxing human colon cancer cells are enriched for self-renewal capacity and depend on Î²-catenin Research Paper

Joshua E. Allen, Wafik S. El-Deiry

Published Feb 18, 2013 · Vol. 4, No. 2 · pp. 184-191

Targeted Therapy of Advanced Gallbladder Cancer and Cholangiocarcinoma with Aggressive Biology: Eliciting Early Response Signals from Phase 1 trials Research Paper

Ishwaria Subbiah, Vivek Subbiah, Apostolia M Tsimberidou, Aung Naing, Ahmed Kaseb, Javle Milind, Siqing Fu, David S Hong, Sarina Piha-Paul, Jenifer Wheler, Kenneth Hess, Filip Janku, Gerald Falchook, Robert A Wolff, Razelle Kurzrock

Published Jan 27, 2013 · Vol. 4, No. 1 · pp. 153-162

Keywords: Gallbladder Cancer, Cholangiocarcinoma, Phase 1 trials

Genomic imbalance of HMMR/RHAMM regulates the sensitivity and response of malignant peripheral nerve sheath tumour cells to aurora kinase inhibition. Research Paper

Pooja Mohan, Joan Castellsague, Jihong Jiang, Kristi Allen, Helen Chen, Oksana Nemirovsky, Melanie Spyra, Kaiji Hu, Lan Kluwe, Miguel Angel Pujana, Alberto Villanueva, Victor F. Mautner, Jonathan J. Keats, Sandra E. Dunn, Conxi Lazaro, Christopher A. Maxwell

Published Jan 9, 2013 · Vol. 4, No. 1 · pp. 80-93

Keywords: Malignant peripheral nerve sheath tumors, Aurora kinase A, RHAMM, TPX2, cancer stem cell

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Blockade of the PDGFR family together with SRC leads to diminished proliferation of colorectal cancer cells Research Paper

Plasma Membrane Proteomics Identifies Biomarkers Associated with MMSET Overexpression in T(4;14) Multiple Myeloma Research Paper

Thymoma Patients Treated in a Phase I Clinic at MD Anderson Cancer Center: Responses to mTOR Inhibitors and Molecular Analyses Research Paper

Powerful Inhibition of Experimental Human Pancreatic Cancers by Receptor Targeted Cytotoxic LH-RH analog AEZS-108 Research Paper

Cross-species genomic and epigenomic landscape of retinoblastoma Research Paper

To grab the stroma by the horns: From biology to cancer therapy with mesenchymal stem cells Review

FAM83B-mediated activation of PI3K/AKT and MAPK signaling cooperates to promote epithelial cell transformation and resistance to targeted therapies. Research Paper

P53 Mutations in Advanced Cancers: Clinical Characteristics, Outcomes, and Correlation between Progression-Free Survival and Bevacizumab-Containing Therapy Research Paper

Combinatorial drug screening identifies compensatory pathway interactions and adaptive resistance mechanisms Research Paper

Effects of CT-Xp Gene Knock down in Melanoma Cell Lines Research Paper

Linked-In: Design and Efficacy of Antibody Drug Conjugates in Oncology Review

Drug-Loaded Nanoparticle Systems And Adult Stem Cells: A Potential Marriage For The Treatment Of Malignant Glioma? Review

Inhibition of U-87 MG glioblastoma by AN-152 (AEZS-108), a targeted cytotoxic analog of luteinizing hormone-releasing hormone Research Paper

Luteolin is a novel p90 ribosomal S6 kinase (RSK) inhibitor that suppresses Notch4 signaling by blocking the activation of Y-box binding protein-1 (YB-1) Research Paper

Efemp1 and p27Kip1 modulate responsiveness of pancreatic cancer cells towards a dual PI3K/mTOR inhibitor in preclinical models Research Paper

Targeted alpha-therapy using [Bi-213]anti-CD20 as novel treatment option for radio- and chemoresistant non-Hodgkin lymphoma cells Research Paper

TRAIL induces apoptosis in oral squamous carcinoma cells: a crosstalk with oncogenic Ras regulated cell surface expression of death receptor 5 Research Paper

Calcein-effluxing human colon cancer cells are enriched for self-renewal capacity and depend on Î²-catenin Research Paper

Targeted Therapy of Advanced Gallbladder Cancer and Cholangiocarcinoma with Aggressive Biology: Eliciting Early Response Signals from Phase 1 trials Research Paper

Genomic imbalance of HMMR/RHAMM regulates the sensitivity and response of malignant peripheral nerve sheath tumour cells to aurora kinase inhibition. Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Blockade of the PDGFR family together with SRC leads to diminished proliferation of colorectal cancer cells Research Paper

Plasma Membrane Proteomics Identifies Biomarkers Associated with MMSET Overexpression in T(4;14) Multiple Myeloma Research Paper

Thymoma Patients Treated in a Phase I Clinic at MD Anderson Cancer Center: Responses to mTOR Inhibitors and Molecular Analyses Research Paper

Powerful Inhibition of Experimental Human Pancreatic Cancers by Receptor Targeted Cytotoxic LH-RH analog AEZS-108 Research Paper

Cross-species genomic and epigenomic landscape of retinoblastoma Research Paper

To grab the stroma by the horns: From biology to cancer therapy with mesenchymal stem cells Review

FAM83B-mediated activation of PI3K/AKT and MAPK signaling cooperates to promote epithelial cell transformation and resistance to targeted therapies. Research Paper

P53 Mutations in Advanced Cancers: Clinical Characteristics, Outcomes, and Correlation between Progression-Free Survival and Bevacizumab-Containing Therapy Research Paper

Combinatorial drug screening identifies compensatory pathway interactions and adaptive resistance mechanisms Research Paper

Effects of CT-Xp Gene Knock down in Melanoma Cell Lines Research Paper

Linked-In: Design and Efficacy of Antibody Drug Conjugates in Oncology Review

Drug-Loaded Nanoparticle Systems And Adult Stem Cells: A Potential Marriage For The Treatment Of Malignant Glioma? Review

Inhibition of U-87 MG glioblastoma by AN-152 (AEZS-108), a targeted cytotoxic analog of luteinizing hormone-releasing hormone Research Paper

Luteolin is a novel p90 ribosomal S6 kinase (RSK) inhibitor that suppresses Notch4 signaling by blocking the activation of Y-box binding protein-1 (YB-1) Research Paper

Efemp1 and p27Kip1 modulate responsiveness of pancreatic cancer cells towards a dual PI3K/mTOR inhibitor in preclinical models Research Paper

Targeted alpha-therapy using [Bi-213]anti-CD20 as novel treatment option for radio- and chemoresistant non-Hodgkin lymphoma cells Research Paper

TRAIL induces apoptosis in oral squamous carcinoma cells: a crosstalk with oncogenic Ras regulated cell surface expression of death receptor 5 Research Paper

Calcein-effluxing human colon cancer cells are enriched for self-renewal capacity and depend on Î²-catenin Research Paper

Targeted Therapy of Advanced Gallbladder Cancer and Cholangiocarcinoma with Aggressive Biology: Eliciting Early Response Signals from Phase 1 trials Research Paper

Genomic imbalance of HMMR/RHAMM regulates the sensitivity and response of malignant peripheral nerve sheath tumour cells to aurora kinase inhibition. Research Paper