The Oncosearch | Oncotarget

A novel immunomodulatory and molecularly targeted strategy for refractory Hodgkinâ€™s lymphoma Brief Reports

Vivek Subbiah, Robert E. Brown, Mary F. McGuire, Jamie Buryanek, Filip Janku, Anas Younes, David Hong

Published Nov 19, 2013 · Vol. 5, No. 1 · pp. 95-102

Keywords: Hodgkin's lymphoma, mTOR, HDAC, Sirolimus, Vorinostat, Targeted therapy

Apoptosis inducers in chronic lymphocytic leukemia Review

Christian Billard

Published Nov 19, 2013 · Vol. 5, No. 2 · pp. 309-325

Keywords: CLL, impaired cell death program, apoptosis-targeted therapies, apoptosis inducers, Bcl-2 family proteins

1 alpha, 25-dihydroxylvitamin D3 promotes Bacillus Calmette-GuÃ©rin immunotherapy of bladder cancer Research Paper

Jong-Wei Hsu, Peng-Nien Yin, Ronald Wood, James Messing, Edward Messing, Yi-Fen Lee

Published Nov 19, 2013 · Vol. 4, No. 12 · pp. 2397-2406

Keywords: vitamin D, Bacillus Calmette-GuÃ©rin, bladder cancer, immunotherapy, interleukin 8

Endothelial hypoxic metabolism in carcinogenesis and dissemination : HIF-A isoforms are a NO metastatic phenomenon Research Perspective

Cristina Branco-Price, Colin E. Evans, Randall S. Johnson

Published Nov 18, 2013 · Vol. 4, No. 12 · pp. 2567-2576

Keywords: Vascular endothelium, hypoxia, metastasis, HIF, HIF isoforms, nitric oxide, cell-specific responses

Ovarian cancer stem-like cells with induced translineage-differentiation capacity and are suppressed by alkaline phosphatase inhibitor Research Paper

Kuei-Chun Liu, Yi-Te Yo, Rui-Lan Huang, Yu-Chi Wang, Yu-Ping Liao, Tien-Shuo Huang, Tai-Kuang Chao, Chi-Kang Lin, Shao-Ju Weng, Kuo-Hsing Ma, Cheng-Chang Chang, Mu-Hsien Yu, Hung-Cheng Lai

Published Nov 16, 2013 · Vol. 4, No. 12 · pp. 2366-2382

Keywords: alkaline phosphatase, cancer stem-like cells, epithelial-mesenchymal transition, epithelial ovarian cancer, levamisole, trans-lineage differentiation

SCF^Î²-TRCP targets MTSS1 for ubiquitination-mediated destruction to regulate cancer cell proliferation and migration Research Paper

Jiateng Zhong, Shavali Shaik, Lixin Wan, Adriana E. Tron, Zhiwei Wang, Liankun Sun, Hiroyuki Inuzuka, Wenyi Wei

Published Nov 6, 2013 · Vol. 4, No. 12 · pp. 2339-2353

Keywords: tumor suppressor, MTSS1, ubiquitination, phosphorylation, migration

FOXD3 is a novel tumor suppressor that affects growth, invasion, metastasis and angiogenesis of neuroblastoma Research Paper

Dan Li, Hong Mei, Meng Qi, Dehua Yang, Xiang Zhao, Xuan Xiang, Jiarui Pu, Kai Huang, Liduan Zheng, Qiangsong Tong

Published Nov 5, 2013 · Vol. 4, No. 11 · pp. 2021-2044

Aberrant chimeric RNA GOLM1-MAK10 encoding a secreted fusion protein as a molecular signature for human esophageal squamous cell carcinoma Research Paper

Hao Zhang, Wan Lin, Kalpana Kannan, Liming Luo, Jing Li, Pei-Wen Chao, Yan Wang, Yu-Ping Chen, Jiang Gu, Laising Yen

Published Nov 1, 2013 · Vol. 4, No. 11 · pp. 2135-2143

Keywords: Transcriptome, transcription-induced chimeric RNAs, GOLM1-MAK10, secreted fusion protein, cancer biomarker, esophageal cancer

A potential therapeutic strategy for chronic lymphocytic leukemia by combining Idelalisib and GS-9973, a novel spleen tyrosine kinase (Syk) inhibitor Research Paper

Russell T Burke, Marc M Loriaux, Kevin S Currie, Scott A Mitchell, Patricia Maciejewski, Astrid S Clarke, Julie A DiPaolo, Brian J Druker, Stephen E Spurgeon, Brian J Lannutti

Published Oct 30, 2013 · Vol. 5, No. 4 · pp. 908-915

Keywords: Chronic Lymphocytic Leukemia, B-cell receptor, signaling pathways, spleen tyrosine kinase, PI3 kinase

Polyubiquitylation of AMF requires cooperation between the gp78 and TRIM25 ubiquitin ligases Research Paper

Ying Wang, Seung-Wook Ha, Tianpeng Zhang, Dhong-Hyo Kho, Avraham Raz, Youming Xie

Published Oct 28, 2013 · Vol. 5, No. 8 · pp. 2044-2051

Keywords: protein ubiquitylation, ubiquitin ligase, AMF, gp78, TRIM25

Impaired angiogenesis and tumor development by inhibition of the mitotic kinesin Eg5 Research Paper

Prisca Exertier, Sophie Javerzat, Baigang Wang, MÃ©lanie Franco, John M. Herbert, Natalia Platonova, Marie Winandy, NadÃ¨ge Pujol, Olivier Nivelles, Sandra Ormenese, Virginie Godard, JÃ¼rgen Becker, Roy Bicknell, Raphael Pineau, JÃ¶rg Wilting, Andreas Bikfalvi, Martin Hagedorn

Published Oct 26, 2013 · Vol. 4, No. 12 · pp. 2302-2316

Keywords: Angiogenesis, Eg5 kinesin, Mklp2 kinesin, VEGF, ispinesib

A novel androgen-regulated isoform of the TSC2 tumour suppressor gene increases cell proliferation Research Paper

Jennifer Munkley, Prabhakar Rajan, Nicholas P. Lafferty, Caroline Dalgliesh, Robert M. Jackson, Craig N. Robson, Hing Y. Leung, David J. Elliott

Published Oct 21, 2013 · Vol. 5, No. 1 · pp. 131-139

Keywords: TSC2, mTOR, mRNA isoform, androgen, prostate cancer

The genetic landscape of anaplastic astrocytoma Research Paper

Patrick J. Killela, Christopher J. Pirozzi, Zachary J. Reitman, Sian Jones, B. Ahmed Rasheed, Eric Lipp, Henry Friedman, Allan H. Friedman, Yiping He, Roger E. McLendon, Darell D. Bigner, Hai Yan

Published Oct 16, 2013 · Vol. 5, No. 6 · pp. 1452-1457

Keywords: Exome sequencing, Anaplastic Astrocytoma, Notch

Chemoresistance to gemcitabine in hepatoma cells induces epithelial-mesenchymal transition and involves activation of PDGF-D pathway Research Paper

Qiong Wu, Rui Wang, Qingling Yang, Xin Hou, Sulian Chen, Yueyue Hou, Changjie Chen, Yan Yang, Lucio Miele, Fazlul Sarkar, Yuqing Chen, Zhiwei Wang

Published Oct 7, 2013 · Vol. 4, No. 11 · pp. 1999-2009

Keywords: Hepatocellular carcinoma, chemoresistance, PDGF-D, EMT, gemcitabine

Mitochondrial oxidative stress is the achilleâ€™s heel of melanoma cells resistant to Braf-mutant inhibitor Research Paper

Paola Corazao-Rozas, Pierre Guerreschi, Manel Jendoubi, Fanny AndrÃ©, AurÃ©lie Jonneaux, Camille Scalbert, Guillaume GarÃ§on, Myriam Mallet-Martino, StÃ©phane Balayssac, Stephane Rocchi, Ariel Savina, Pierre Formstecher, Laurent Mortier, Jerome Kluza, Philippe Marchetti

Published Oct 6, 2013 · Vol. 4, No. 11 · pp. 1986-1998

Keywords: metabolism, oxidative phosphorylation, elesclomol, ROS

The deubiquitinating enzyme USP17 is associated with non-small cell lung cancer (NSCLC) recurrence and metastasis Research Paper

Cheryl McFarlane, Suzanne McFarlane, Ian Paul, Kenneth Arthur, Michael Scheaff, Keith Kerr, Michael Stevenson, Dean A Fennell, James A Johnston

Published Oct 3, 2013 · Vol. 4, No. 10 · pp. 1836-1843

Keywords: deubiquitination, USP17, NSCLC

p53 regulates the transcription of the anti-inflammatory molecule developmental endothelial locus-1 (Del-1) Research Paper

Hyesoon Kim, Seung-Hwan Lee, Mi-Ni Lee, Goo Taeg Oh, Kyung-Chul Choi, Eun Young Choi

Published Oct 3, 2013 · Vol. 4, No. 11 · pp. 1976-1985

Keywords: p53, inflammation, endothelial cell, Del-1

Broad-spectrum anti-tumor and anti-metastatic DNA vaccine based on p62-encoding vector Research Paper

Franco Venanzi, Victor Shifrin, Michael Y. Sherman, Vladimir Gabai, Oleg Kisilev, Andrey Komissarov, Mikhail Grudinin, Maria Shartakova, Ekaterina Romanovskaya-Romanko, Yuri Kudryavets, Natalya Bezdenezhnykh, Oleksandra Lykhova, Nadiia Semesyuk, Antonio Concetti, Anatoly Tsyb, Marina Filimonova, Victoria Makarchuk, Raisa Yakubovsky, Andrey Chursov, Vita Shcherbinina, Alexander Shneider

Published Oct 2, 2013 · Vol. 4, No. 10 · pp. 1829-1835

Keywords: cancer immunotherapy, DNA vaccine, autophagy, metastases

Identification of a novel peptide that blocks basic fibroblast growth factor-mediated cell proliferation Research Paper

Xiaoping Wu, Huixian Huang, Cong Wang, Shaoqiang Lin, Yadong Huang, Yi Wang, Guang Liang, Qiuxia Yan, Jian Xiao, Jianzhang Wu, Yongguang Yang, Xiaokun Li

Published Oct 1, 2013 · Vol. 4, No. 10 · pp. 1819-1828

The FAK scaffold inhibitor C4 disrupts FAK-VEGFR-3 signaling and inhibits pancreatic cancer growth Research Paper

Elena Kurenova, Jianqun Liao, Di-Hua He, Darrell Hunt, Michael Yemma, Wiam Bshara, Mukund Seshadri, William G Cance

Published Sep 30, 2013 · Vol. 4, No. 10 · pp. 1632-1646

Keywords: FAK Scaffold Inhibitor, pancreatic cancer, FAK-VEGFR-3 interaction, protein-protein interaction

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

A novel immunomodulatory and molecularly targeted strategy for refractory Hodgkinâ€™s lymphoma Brief Reports

Apoptosis inducers in chronic lymphocytic leukemia Review

1 alpha, 25-dihydroxylvitamin D3 promotes Bacillus Calmette-GuÃ©rin immunotherapy of bladder cancer Research Paper

Endothelial hypoxic metabolism in carcinogenesis and dissemination : HIF-A isoforms are a NO metastatic phenomenon Research Perspective

Ovarian cancer stem-like cells with induced translineage-differentiation capacity and are suppressed by alkaline phosphatase inhibitor Research Paper

SCF^Î²-TRCP targets MTSS1 for ubiquitination-mediated destruction to regulate cancer cell proliferation and migration Research Paper

FOXD3 is a novel tumor suppressor that affects growth, invasion, metastasis and angiogenesis of neuroblastoma Research Paper

Aberrant chimeric RNA GOLM1-MAK10 encoding a secreted fusion protein as a molecular signature for human esophageal squamous cell carcinoma Research Paper

A potential therapeutic strategy for chronic lymphocytic leukemia by combining Idelalisib and GS-9973, a novel spleen tyrosine kinase (Syk) inhibitor Research Paper

Polyubiquitylation of AMF requires cooperation between the gp78 and TRIM25 ubiquitin ligases Research Paper

Impaired angiogenesis and tumor development by inhibition of the mitotic kinesin Eg5 Research Paper

A novel androgen-regulated isoform of the TSC2 tumour suppressor gene increases cell proliferation Research Paper

The genetic landscape of anaplastic astrocytoma Research Paper

Chemoresistance to gemcitabine in hepatoma cells induces epithelial-mesenchymal transition and involves activation of PDGF-D pathway Research Paper

Mitochondrial oxidative stress is the achilleâ€™s heel of melanoma cells resistant to Braf-mutant inhibitor Research Paper

The deubiquitinating enzyme USP17 is associated with non-small cell lung cancer (NSCLC) recurrence and metastasis Research Paper

p53 regulates the transcription of the anti-inflammatory molecule developmental endothelial locus-1 (Del-1) Research Paper

Broad-spectrum anti-tumor and anti-metastatic DNA vaccine based on p62-encoding vector Research Paper

Identification of a novel peptide that blocks basic fibroblast growth factor-mediated cell proliferation Research Paper

The FAK scaffold inhibitor C4 disrupts FAK-VEGFR-3 signaling and inhibits pancreatic cancer growth Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

A novel immunomodulatory and molecularly targeted strategy for refractory Hodgkinâ€™s lymphoma Brief Reports

Apoptosis inducers in chronic lymphocytic leukemia Review

1 alpha, 25-dihydroxylvitamin D3 promotes Bacillus Calmette-GuÃ©rin immunotherapy of bladder cancer Research Paper

Endothelial hypoxic metabolism in carcinogenesis and dissemination : HIF-A isoforms are a NO metastatic phenomenon Research Perspective

Ovarian cancer stem-like cells with induced translineage-differentiation capacity and are suppressed by alkaline phosphatase inhibitor Research Paper

SCFÎ²-TRCP targets MTSS1 for ubiquitination-mediated destruction to regulate cancer cell proliferation and migration Research Paper

FOXD3 is a novel tumor suppressor that affects growth, invasion, metastasis and angiogenesis of neuroblastoma Research Paper

Aberrant chimeric RNA GOLM1-MAK10 encoding a secreted fusion protein as a molecular signature for human esophageal squamous cell carcinoma Research Paper

A potential therapeutic strategy for chronic lymphocytic leukemia by combining Idelalisib and GS-9973, a novel spleen tyrosine kinase (Syk) inhibitor Research Paper

Polyubiquitylation of AMF requires cooperation between the gp78 and TRIM25 ubiquitin ligases Research Paper

Impaired angiogenesis and tumor development by inhibition of the mitotic kinesin Eg5 Research Paper

A novel androgen-regulated isoform of the TSC2 tumour suppressor gene increases cell proliferation Research Paper

The genetic landscape of anaplastic astrocytoma Research Paper

Chemoresistance to gemcitabine in hepatoma cells induces epithelial-mesenchymal transition and involves activation of PDGF-D pathway Research Paper

Mitochondrial oxidative stress is the achilleâ€™s heel of melanoma cells resistant to Braf-mutant inhibitor Research Paper

The deubiquitinating enzyme USP17 is associated with non-small cell lung cancer (NSCLC) recurrence and metastasis Research Paper

p53 regulates the transcription of the anti-inflammatory molecule developmental endothelial locus-1 (Del-1) Research Paper

Broad-spectrum anti-tumor and anti-metastatic DNA vaccine based on p62-encoding vector Research Paper

Identification of a novel peptide that blocks basic fibroblast growth factor-mediated cell proliferation Research Paper

The FAK scaffold inhibitor C4 disrupts FAK-VEGFR-3 signaling and inhibits pancreatic cancer growth Research Paper

SCF^Î²-TRCP targets MTSS1 for ubiquitination-mediated destruction to regulate cancer cell proliferation and migration Research Paper