The Oncosearch | Oncotarget

A high-content morphological screen identifies novel microRNAs that regulate neuroblastoma cell differentiation Research Paper

Zhenze Zhao, Xiuye Ma, Tzu-Hung Hsiao, Gregory Lin, Adam Kosti, Xiaojie Yu, Uthra Suresh, Yidong Chen, Gail E. Tomlinson, Alexander Pertsemlidis, Liqin Du

Published Feb 28, 2014 · Vol. 5, No. 9 · pp. 2499-2512

Keywords: neuroblastoma, microRNA, high-content screen, differentiation, differentiation therapy

Inhibition of HER2-Integrin signaling by Cucurbitacin B leads to in vitro and in vivo breast tumor growth suppression Research Paper

Parul Gupta, Sanjay K. Srivastava

Published Feb 25, 2014 · Vol. 5, No. 7 · pp. 1812-1828

Keywords: HER2, Breast Cancer, Integrins, Apoptosis, Tumor growth

Galectin-3 induces cell migration via a calcium-sensitive MAPK/ERK1/2 pathway Research Paper

Xiaoge Gao, Vitaly Balan, Guihua Tai, Avraham Raz

Published Feb 19, 2014 · Vol. 5, No. 8 · pp. 2077-2084

Utilization of Rad51C promoter for transcriptional targeting of cancer cells Research Paper

Yan Cao, Yan Xu, Lei Zhang, Zhen Li, Ying Jiang, Xiao Tian, Andrei Seluanov, Vera Gorbunova, Zhiyong Mao

Published Feb 19, 2014 · Vol. 5, No. 7 · pp. 1805-1811

SENP5 mediates breast cancer invasion via a TGFÎ²RI SUMOylation cascade Research Paper

Rivki Cashman, Helit Cohen, Rotem Ben-Hamo, Alona Zilberberg, Sol Efroni

Published Feb 18, 2014 · Vol. 5, No. 4 · pp. 1071-1082

Ribosomal proteins as unrevealed caretakers for cellular stress and genomic instability Review

Tae-Hyung Kim, Patrick Leslie, Yanping Zhang

Published Feb 18, 2014 · Vol. 5, No. 4 · pp. 860-871

The histone demethylase JMJD1A induces cell migration and invasion by up-regulating the expression of the long noncoding RNA MALAT1 Research Paper

Andrew E. Tee, Dora Ling, Charlotte Nelson, Bernard Atmadibrata, Marcel E. Dinger, Ning Xu, Tamio Mizukami, Pei Y. Liu, Bing Liu, Belamy Cheung, Eddy Pasquier, Michelle Haber, Murray D. Norris, Takayoshi Suzuki, Glenn M. Marshall, Tao Liu

Published Feb 18, 2014 · Vol. 5, No. 7 · pp. 1793-1804

Targeting Src-mediated Tyr216 phosphorylation and activation of GSK-3 in prostate cancer cells inhibit prostate cancer progression in vitro and in vivo Research Paper

Anna Goc, Belal Al-Husein Al-Husein, Katerina Katsanevas, Alison Steinbach, Uvette Lou, Harika Sabbineni, David L. DeRemer, Payaningal R. Somanath

Published Feb 15, 2014 · Vol. 5, No. 3 · pp. 775-787

Hydrogen peroxide/ATR-Chk2 activation mediates p53 protein stabilization and anti-cancer activity of cheliensisin A in human cancer cells Research Paper

Jingjie Zhang, Guangxun Gao, Liang Chen, Jingxia Li, Xu Deng, Qin-shi Zhao, Chuanshu Huang

Published Feb 14, 2014 · Vol. 5, No. 3 · pp. 841-852

TBX2 represses CST6 resulting in uncontrolled legumain activity to sustain breast cancer proliferation: a novel cancer-selective target pathway with therapeutic opportunities Research Paper

Zenobia C. D'Costa, Catherine A. Higgins, Chee Wee Ong, Gareth Irwin, David Boyle, Darragh G. McArt, Karen McCloskey, Niamh E. Buckley, Nyree T. Crawford, Lalitha Thiagarajan, James T. Murray, Richard D. Kennedy, Karl A. Mulligan, Denis P. Harkin, David J.J. Waugh, Chris J. Scott, Manuel Salto-Tellez, Richard Williams, Paul B. Mullan

Published Feb 8, 2014 · Vol. 5, No. 6 · pp. 1609-1620

Keywords: TBX2, CST6, LGMN, breast cancer

Identification of a long non-coding RNA as a novel biomarker and potential therapeutic target for metastatic prostate cancer Research Paper

Francesco Crea, Akira Watahiki, Luca Quagliata, Hui Xue, Larissa Pikor, Abhijit Parolia, Yuwei Wang, Dong Lin, Wan L. Lam, William L. Farrar, Takao Isogai, Rudolf Morant, Serenella Castori-Eppenberger, Kim N. Chi, Yuzhuo Wang, Cheryl D. Helgason

Published Feb 6, 2014 · Vol. 5, No. 3 · pp. 764-774

Prostate cancer-derived CCN3 induces M2 macrophage infiltration and contributes to angiogenesis in prostate cancer microenvironment Research Paper

Po-Chun Chen, Hsu-Chen Cheng, John Wang, Shin-Wei Wang, Huai-Ching Tai, Chiao-Wen Lin, Chih-Hsin Tang

Published Feb 4, 2014 · Vol. 5, No. 6 · pp. 1595-1608

Keywords: CCN3, VEGF, Prostate cancer, M2 macrophage, angiogenesis

Roles of neutrophil gelatinase-associated lipocalin (NGAL) in human cancer Research Paper

Saverio Candido, Roberta Maestro, Jerry Polesel, Alessia Catania, Francesca Maira, Santo S. Signorelli, James A. McCubrey, Massimo Libra

Published Feb 1, 2014 · Vol. 5, No. 6 · pp. 1576-1594

Keywords: NGAL, LCN2, Lipocalin 2, mRNA expression, cancer, biomarker, prognostic factor, metastasis, protein expression

Role of the polypeptide N-acetylgalactosaminyltransferase 3 in ovarian cancer progression: possible implications in abnormal mucin O-glycosylation Research Paper

Zhi-Qiang Wang, Magdalena Bachvarova, Chantale Morin, Marie Plante, Jean Gregoire, Marie-Claude Renaud, Alexandra Sebastianelli, Dimcho Bachvarov

Published Jan 27, 2014 · Vol. 5, No. 2 · pp. 544-560

Keywords: GALNT3, epithelial ovarian cancer, DNA hypomethylation, progression-free survival, microarrays, mucin O-glycosylation

First Mnks degrading agents block phosphorylation of eIF4E, induce apoptosis, inhibit cell growth, migration and invasion in triple negative and Her2-overexpressing breast cancer cell lines Research Paper

Senthilmurugan Ramalingam, Lalji Gediya, Andrew K. Kwegyir-Afful, Vidya P. Ramamurthy, Puranik Purushottamachar, Hannah Mbatia, Vincent C.O. Njar

Published Jan 25, 2014 · Vol. 5, No. 2 · pp. 530-543

Keywords: Breast cancer, RAMBA retinamides, eukaryotic initiation factor 4E, Mnk1/2

Hypoxia inducible factor-1 alpha as a therapeutic target in multiple myeloma Research Paper

Enrica Borsi, Giulia Perrone, Carolina Terragna, Marina Martello, Angela F Dico, Giancarlo Solaini, Alessandra Baracca, Gianluca Sgarbi, Gianandrea Pasquinelli, Sabrina Valente, Elena Zamagni, Paola Tacchetti, Giovanni Martinelli, Michele Cavo

Published Jan 23, 2014 · Vol. 5, No. 7 · pp. 1779-1792

Keywords: HIF-1Î±, Multiple Myeloma, Cell cycle, Mitochondria, Warburg effect

microRNA expression profiling identifies a four microRNA signature as a novel diagnostic and prognostic biomarker in triple negative breast cancers Priority Research Paper

Pierluigi Gasparini, Luciano Cascione, Matteo Fassan, Francesca Lovat, Gulnur Guler, Serdar Balci, Cigdem Irkkan, Carl Morrison, Carlo M. Croce, Charles L. Shapiro, Kay Huebner

Published Jan 21, 2014 · Vol. 5, No. 5 · pp. 1174-1184

Keywords: Triple Negative breast cancer, microRNA, five markers, prognosis, treatments, outcome

Engineered repressors are potent inhibitors of androgen receptor activity Research Paper

Greg N. Brooke, Sue M. Powell, Derek N. Lavery, Jonathan Waxman, Laki Buluwela, Simak Ali, Charlotte L. Bevan

Published Jan 21, 2014 · Vol. 5, No. 4 · pp. 959-969

Keywords: androgen, prostate cancer, hormone therapy, transcription, AR, MAD, KOX

Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR Research Paper

Ulrike M. Litzenburger, Christiane A. Opitz, Felix Sahm, Katharina J. Rauschenbach, Saskia Trump, Marcus Winter, Martina Ott, Katharina Ochs, Christian Lutz, Xiangdong Liu, Natasa Anastasov, Irina Lehmann, Thomas HÃ¶fer, Andreas von Deimling, Wolfgang Wick, Michael Platten

Published Jan 20, 2014 · Vol. 5, No. 4 · pp. 1038-1051

Keywords: IDO, immunosuppression, autoactivation loop

EGFR endocytosis is a novel therapeutic target in lung cancer with wild-type EGFR Research Paper

Ukhyun Jo, Kyong Hwa Park, Young Mi Whang, Jae Sook Sung, Nam Hee Won, Jong Kuk Park, Yeul Hong Kim

Published Jan 16, 2014 · Vol. 5, No. 5 · pp. 1265-1278

Keywords: EGFR, endocytosis, gefitinib, lung cancer, Rab25

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A high-content morphological screen identifies novel microRNAs that regulate neuroblastoma cell differentiation Research Paper

Inhibition of HER2-Integrin signaling by Cucurbitacin B leads to in vitro and in vivo breast tumor growth suppression Research Paper

Galectin-3 induces cell migration via a calcium-sensitive MAPK/ERK1/2 pathway Research Paper

Utilization of Rad51C promoter for transcriptional targeting of cancer cells Research Paper

SENP5 mediates breast cancer invasion via a TGFÎ²RI SUMOylation cascade Research Paper

Ribosomal proteins as unrevealed caretakers for cellular stress and genomic instability Review

The histone demethylase JMJD1A induces cell migration and invasion by up-regulating the expression of the long noncoding RNA MALAT1 Research Paper

Targeting Src-mediated Tyr216 phosphorylation and activation of GSK-3 in prostate cancer cells inhibit prostate cancer progression in vitro and in vivo Research Paper

Hydrogen peroxide/ATR-Chk2 activation mediates p53 protein stabilization and anti-cancer activity of cheliensisin A in human cancer cells Research Paper

TBX2 represses CST6 resulting in uncontrolled legumain activity to sustain breast cancer proliferation: a novel cancer-selective target pathway with therapeutic opportunities Research Paper

Identification of a long non-coding RNA as a novel biomarker and potential therapeutic target for metastatic prostate cancer Research Paper

Prostate cancer-derived CCN3 induces M2 macrophage infiltration and contributes to angiogenesis in prostate cancer microenvironment Research Paper

Roles of neutrophil gelatinase-associated lipocalin (NGAL) in human cancer Research Paper

Role of the polypeptide N-acetylgalactosaminyltransferase 3 in ovarian cancer progression: possible implications in abnormal mucin O-glycosylation Research Paper

First Mnks degrading agents block phosphorylation of eIF4E, induce apoptosis, inhibit cell growth, migration and invasion in triple negative and Her2-overexpressing breast cancer cell lines Research Paper

Hypoxia inducible factor-1 alpha as a therapeutic target in multiple myeloma Research Paper

microRNA expression profiling identifies a four microRNA signature as a novel diagnostic and prognostic biomarker in triple negative breast cancers Priority Research Paper

Engineered repressors are potent inhibitors of androgen receptor activity Research Paper

Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR Research Paper

EGFR endocytosis is a novel therapeutic target in lung cancer with wild-type EGFR Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

A high-content morphological screen identifies novel microRNAs that regulate neuroblastoma cell differentiation Research Paper

Inhibition of HER2-Integrin signaling by Cucurbitacin B leads to in vitro and in vivo breast tumor growth suppression Research Paper

Galectin-3 induces cell migration via a calcium-sensitive MAPK/ERK1/2 pathway Research Paper

Utilization of Rad51C promoter for transcriptional targeting of cancer cells Research Paper

SENP5 mediates breast cancer invasion via a TGFÎ²RI SUMOylation cascade Research Paper

Ribosomal proteins as unrevealed caretakers for cellular stress and genomic instability Review

The histone demethylase JMJD1A induces cell migration and invasion by up-regulating the expression of the long noncoding RNA MALAT1 Research Paper

Targeting Src-mediated Tyr216 phosphorylation and activation of GSK-3 in prostate cancer cells inhibit prostate cancer progression in vitro and in vivo Research Paper

Hydrogen peroxide/ATR-Chk2 activation mediates p53 protein stabilization and anti-cancer activity of cheliensisin A in human cancer cells Research Paper

TBX2 represses CST6 resulting in uncontrolled legumain activity to sustain breast cancer proliferation: a novel cancer-selective target pathway with therapeutic opportunities Research Paper

Identification of a long non-coding RNA as a novel biomarker and potential therapeutic target for metastatic prostate cancer Research Paper

Prostate cancer-derived CCN3 induces M2 macrophage infiltration and contributes to angiogenesis in prostate cancer microenvironment Research Paper

Roles of neutrophil gelatinase-associated lipocalin (NGAL) in human cancer Research Paper

Role of the polypeptide N-acetylgalactosaminyltransferase 3 in ovarian cancer progression: possible implications in abnormal mucin O-glycosylation Research Paper

First Mnks degrading agents block phosphorylation of eIF4E, induce apoptosis, inhibit cell growth, migration and invasion in triple negative and Her2-overexpressing breast cancer cell lines Research Paper

Hypoxia inducible factor-1 alpha as a therapeutic target in multiple myeloma Research Paper

microRNA expression profiling identifies a four microRNA signature as a novel diagnostic and prognostic biomarker in triple negative breast cancers Priority Research Paper

Engineered repressors are potent inhibitors of androgen receptor activity Research Paper

Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR Research Paper

EGFR endocytosis is a novel therapeutic target in lung cancer with wild-type EGFR Research Paper