The Oncosearch | Oncotarget

DNA-demethylating and anti-tumor activity of synthetic miR-29b mimics in multiple myeloma Research Paper

Nicola Amodio, Marzia Leotta, Dina Bellizzi, Maria Teresa Di Martino, Patrizia D'Aquila, Marta Lionetti, Fernanda Fabiani, Emanuela Leone, Anna Maria GullÃ, Giuseppe Passarino, Michele Caraglia, Massimo Negrini, Antonino Neri, Antonio Giordano, Pierosandro Tagliaferri, Pierfrancesco Tassone

Published Oct 21, 2012 · Vol. 3, No. 10 · pp. 1246-1258

Keywords: miRNA, miR-29b, multiple myeloma, DNMT

Too much AKT turns PAX3-FKHR dead: A prospect of novel therapeutic strategy for alveolar rhabdomyosarcoma Editorial

Mathivanan Jothi, Asoke K. Mal

Published Oct 17, 2012 · Vol. 3, No. 10 · pp. 1064-1065

Recurrent targets of aberrant somatic hypermutation in lymphoma Research Paper

Alireza Hadj Khodabakhshi, Ryan D Morin, Anthony P Fejes, Andrew J Mungall, Karen L Mungall, Madison Bolger-Munro, Nathalie A Johnson, Joseph M Connors, Randy D Gascoyne, Marco A Marra, Inanc Birol, Steven JM Jones

Published Oct 12, 2012 · Vol. 3, No. 11 · pp. 1308-1319

Keywords: Aberrant somatic hypermutation, Genome wide study, Diffuse large B-cell lymphoma, Genomic rearrangements.

HLX in AML: novel prognostic and therapeutic target Editorial

Ashley Pandolfi, Ulrich Steidl

Published Oct 11, 2012 · Vol. 3, No. 10 · pp. 1059-1060

Targeting JNK-interacting-protein-1 (JIP1) sensitises osteosarcoma to doxorubicin Research Paper

Jantine Posthuma De Boer, Pim W. van Egmond, Marco N. Helder, RenÃ©e X. de Menezes, Anne-Marie Cleton-Jansen, Jeroen A.M. BeliÃ«n, Henk M.W. Verheul, Barend J. van Royen, Gert-Jan J.L. Kaspers, Victor W. van Beusechem

Published Sep 28, 2012 · Vol. 3, No. 10 · pp. 1169-1181

Keywords: osteosarcoma, functional genomics, siRNA, chemosensitisation, JIP1

FOXP3, a novel glioblastoma oncosuppressor, affects proliferation and migration Research Paper

VÃ©ronique Frattini, Federica Pisati, Maria Carmela Speranza, Pietro Luigi Poliani, Gianmaria FrigÃ©, Gabriele Cantini, Dimos Kapetis, Manuela Cominelli, Alessandra Rossi, Gaetano Finocchiaro, Serena Pellegatta

Published Sep 22, 2012 · Vol. 3, No. 10 · pp. 1146-1157

Keywords: FOXP3, glioblastoma, neurospheres, proliferation, migration

DNA damage-induced activation of ATM promotes Î²-TRCP-mediated Mdm2 ubiquitination and destruction Research Paper

Zhiwei Wang, Hiroyuki Inuzuka, Jiateng Zhong, Hidefumi Fukushima, Lixin Wan, Pengda Liu, Wenyi Wei

Published Sep 11, 2012 · Vol. 3, No. 9 · pp. 1026-1035

Keywords: Mdm2, ATM, CKI, phosphorylation, beta-TRCP, ubiquitination, DNA damage

Glyceraldehyde-3-Phosphate Dehydrogenase: A Promising Target for Molecular Therapy in Hepatocellular Carcinoma Review

Shanmugasundaram Ganapathy-Kanniappan, Rani Kunjithapatham, Jean-Francois Geschwind

Published Sep 7, 2012 · Vol. 3, No. 9 · pp. 940-953

Keywords: GAPDH, HCC, 3-bromopyruvate

Novel Antagonists of Heparin Binding Growth Factors Editorial

Fabiola Cecchi, Donald P Bottaro

Published Sep 4, 2012 · Vol. 3, No. 9 · pp. 911-912

Genetic and epigenetic loss of microRNA-31 leads to feed-forward expression of EZH2 in melanoma Research Paper

Irfan A Asangani, Paul W Harms, Lois Dodson, Mithil Pandhi, Lakshmi P Kunju, Christopher A Maher, Douglas R Fullen, Timothy M Johnson, Thomas J Giordano, Nallasivam Palanisamy, Arul M Chinnaiyan

Published Aug 31, 2012 · Vol. 3, No. 9 · pp. 1011-1025

Keywords: microRNA-31, melanoma, tumor suppressor, EZH2, DZNep

A lesson for cancer research: placental microarray gene analysis in preeclampsia Review

Frank Louwen, Cornelia Muschol-Steinmetz, Josha Reinhard, Anke Reitter, Juping Yuan

Published Aug 23, 2012 · Vol. 3, No. 8 · pp. 759-773

Keywords: preeclampsia, cancer cells, invasion, angiogenesis, immune tolerance

Meta-analysis of clinical data using human meiotic genes identifies a novel cohort of highly restricted cancer-specific marker genes. Research Paper

Julia Feichtinger, Ibrahim Aldeailej, Rebecca Anderson, Mikhlid Almatrafi, Naif Alsiwiehri, keith Griffiths, Nicholas Stuart, Jane A Wakeman, Lee Larcombe, Ramsay James McFarlane

Published Aug 13, 2012 · Vol. 3, No. 8 · pp. 843-853

Keywords: cancer biomarkers, cancer testes antigens, oncogenes, meiosis, PRDM9, cohesins drug targets

NEDD9, a novel target of miR-145, increases the invasiveness of glioblastoma Research Paper

Maria Carmela Speranza, VÃ©ronique Frattini, Federica Pisati, Dimos Kapetis, Paola Porrati, Marica Eoli, Serena Pellegatta, Gaetano Finocchiaro

Published Aug 5, 2012 · Vol. 3, No. 7 · pp. 723-734

Keywords: miR-145, NEDD9, invasion, progression, glioma, glioblastoma

Circulating tumor-derived mutant mitochondrial DNA: a predictive biomarker of clinical prognosis in human squamous cell carcinoma. Brief Reports

Katsuhiro Uzawa, Takao Baba, Fumihiko Uchida, Masanobu Yamatoji, Atsushi Kasamatsu, Yosuke Sakamoto, Katsunori Ogawara, Masashi Shiiba, Hiroki Bukawa, Hideki Tanzawa

Published Jul 25, 2012 · Vol. 3, No. 7 · pp. 670-677

Keywords: squamous cell carcinoma, mitochondrial DNA, high-resolution melting curve analysis, circulating tumor-derived DNA, prognosis

Computer-Based Identification of a Novel LIMK1/2 Inhibitor that Synergizes with Salirasib to Destabilize the Actin Cytoskeleton Research Paper

Efrat Mashiach Farkash, Roni Rak, Galit Elad-Sfadia, Roni Haklai, Shmuel Carmeli, Yoel Kloog, Haim Wolfson

Published Jul 7, 2012 · Vol. 3, No. 6 · pp. 629-639

Keywords: Cofilin, Ras, Rac, Rho, LIMK

Targeting of Rac GTPases blocks the spread of intact human breast cancer Research Paper

Elad Katz, Andrew H. Sims, Duncan Sproul, Helen Caldwell, J. Michael Dixon, Richard R. Meehan, David J. Harrison

Published Jun 9, 2012 · Vol. 3, No. 6 · pp. 608-619

Keywords: breast cancer, gtpases, rac1, stat3, invasion

Novel Therapeutic Targets in the Brain Tumor Microenvironment Research Perspective

Joanna J. Phillips

Published May 25, 2012 · Vol. 3, No. 5 · pp. 568-575

A novel co-operative mechanism linking TGFÎ² and Lyn kinase activation to imatinib resistance in chronic myeloid leukaemia cells Brief Reports

Andrew Chantry, Paul G Smith, Hideo Tanaka

Published May 24, 2012 · Vol. 3, No. 5 · pp. 518-524

Keywords: Transforming growth factor-Î², Smads, ubiquitin, c-cbl, Lyn, leukaemia

The Hsp90 inhibitor NVP-AUY922-AG inhibits NF-ÎºB signaling, overcomes microenvironmental cytoprotection and is highly synergistic with fludarabine in primary CLL cells Research Paper

Elisabeth J. Walsby, Laurence Pearce, Alan K. Burnett, Chris Fegan, Chris Pepper

Published May 19, 2012 · Vol. 3, No. 5 · pp. 525-534

Keywords: Hsp90, CLL, apoptosis, synergy, NF-ÎºB

Singular v Dual Inhibition of SNF2L and Its Isoform, SNF2LT, Have Similar Effects on DNA Damage but Opposite Effects on the DNA Damage Response, Cancer Cell Growth Arrest and Apoptosis Research Paper

Yin Ye, Yi Xiao, Wenting Wang, Jian-Xin Gao, Kurtis Yearsley, Quintao Yan, Sanford H. Barsky

Published May 9, 2012 · Vol. 3, No. 4 · pp. 475-489

Keywords: SNF2LT, chromatin remodelling ATPase, cell cycle checkpoints

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DNA-demethylating and anti-tumor activity of synthetic miR-29b mimics in multiple myeloma Research Paper

Too much AKT turns PAX3-FKHR dead: A prospect of novel therapeutic strategy for alveolar rhabdomyosarcoma Editorial

Recurrent targets of aberrant somatic hypermutation in lymphoma Research Paper

HLX in AML: novel prognostic and therapeutic target Editorial

Targeting JNK-interacting-protein-1 (JIP1) sensitises osteosarcoma to doxorubicin Research Paper

FOXP3, a novel glioblastoma oncosuppressor, affects proliferation and migration Research Paper

DNA damage-induced activation of ATM promotes Î²-TRCP-mediated Mdm2 ubiquitination and destruction Research Paper

Glyceraldehyde-3-Phosphate Dehydrogenase: A Promising Target for Molecular Therapy in Hepatocellular Carcinoma Review

Novel Antagonists of Heparin Binding Growth Factors Editorial

Genetic and epigenetic loss of microRNA-31 leads to feed-forward expression of EZH2 in melanoma Research Paper

A lesson for cancer research: placental microarray gene analysis in preeclampsia Review

Meta-analysis of clinical data using human meiotic genes identifies a novel cohort of highly restricted cancer-specific marker genes. Research Paper

NEDD9, a novel target of miR-145, increases the invasiveness of glioblastoma Research Paper

Circulating tumor-derived mutant mitochondrial DNA: a predictive biomarker of clinical prognosis in human squamous cell carcinoma. Brief Reports

Computer-Based Identification of a Novel LIMK1/2 Inhibitor that Synergizes with Salirasib to Destabilize the Actin Cytoskeleton Research Paper

Targeting of Rac GTPases blocks the spread of intact human breast cancer Research Paper

Novel Therapeutic Targets in the Brain Tumor Microenvironment Research Perspective

A novel co-operative mechanism linking TGFÎ² and Lyn kinase activation to imatinib resistance in chronic myeloid leukaemia cells Brief Reports

The Hsp90 inhibitor NVP-AUY922-AG inhibits NF-ÎºB signaling, overcomes microenvironmental cytoprotection and is highly synergistic with fludarabine in primary CLL cells Research Paper

Singular v Dual Inhibition of SNF2L and Its Isoform, SNF2LT, Have Similar Effects on DNA Damage but Opposite Effects on the DNA Damage Response, Cancer Cell Growth Arrest and Apoptosis Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

DNA-demethylating and anti-tumor activity of synthetic miR-29b mimics in multiple myeloma Research Paper

Too much AKT turns PAX3-FKHR dead: A prospect of novel therapeutic strategy for alveolar rhabdomyosarcoma Editorial

Recurrent targets of aberrant somatic hypermutation in lymphoma Research Paper

HLX in AML: novel prognostic and therapeutic target Editorial

Targeting JNK-interacting-protein-1 (JIP1) sensitises osteosarcoma to doxorubicin Research Paper

FOXP3, a novel glioblastoma oncosuppressor, affects proliferation and migration Research Paper

DNA damage-induced activation of ATM promotes Î²-TRCP-mediated Mdm2 ubiquitination and destruction Research Paper

Glyceraldehyde-3-Phosphate Dehydrogenase: A Promising Target for Molecular Therapy in Hepatocellular Carcinoma Review

Novel Antagonists of Heparin Binding Growth Factors Editorial

Genetic and epigenetic loss of microRNA-31 leads to feed-forward expression of EZH2 in melanoma Research Paper

A lesson for cancer research: placental microarray gene analysis in preeclampsia Review

Meta-analysis of clinical data using human meiotic genes identifies a novel cohort of highly restricted cancer-specific marker genes. Research Paper

NEDD9, a novel target of miR-145, increases the invasiveness of glioblastoma Research Paper

Circulating tumor-derived mutant mitochondrial DNA: a predictive biomarker of clinical prognosis in human squamous cell carcinoma. Brief Reports

Computer-Based Identification of a Novel LIMK1/2 Inhibitor that Synergizes with Salirasib to Destabilize the Actin Cytoskeleton Research Paper

Targeting of Rac GTPases blocks the spread of intact human breast cancer Research Paper

Novel Therapeutic Targets in the Brain Tumor Microenvironment Research Perspective

A novel co-operative mechanism linking TGFÎ² and Lyn kinase activation to imatinib resistance in chronic myeloid leukaemia cells Brief Reports

The Hsp90 inhibitor NVP-AUY922-AG inhibits NF-ÎºB signaling, overcomes microenvironmental cytoprotection and is highly synergistic with fludarabine in primary CLL cells Research Paper

Singular v Dual Inhibition of SNF2L and Its Isoform, SNF2LT, Have Similar Effects on DNA Damage but Opposite Effects on the DNA Damage Response, Cancer Cell Growth Arrest and Apoptosis Research Paper