The Oncosearch | Oncotarget

Profiling the circulating mRNA transcriptome in human liver disease Research Paper

Aejaz Sayeed, Brielle E. Dalvano, David E. Kaplan, Usha Viswanathan, John Kulp, Alhaji H. Janneh, Lu-Yu Hwang, Adam Ertel, Cataldo Doria, Timothy Block

Published May 23, 2020 · Vol. 11, No. 23 · pp. 2216-2232

Keywords: hepatocellular carcinoma, circulating transcripts, biomarkers, liver cirrhosis, extracellular vesicles

Panaxynol, a bioactive component of American ginseng, targets macrophages and suppresses colitis in mice Priority Research Paper

Anusha Chaparala, Deepak Poudyal, Hossam Tashkandi, Erin E. Witalison, Alexander A. Chumanevich, Jenna L. Hofseth, Ivy Nguyen, Olivia Hardy, Douglas L. Pittman, Michael D. Wyatt, Anthony Windust, Elizabeth A. Murphy, Mitzi Nagarkatti, Prakash Nagarkatti, Lorne J. Hofseth

Published Apr 30, 2020 · Vol. 11, No. 22 · pp. 2026-2036

Keywords: inflammatory bowel diseases, ulcerative colitis, American ginseng, panaxynol, macrophages

Apolipoprotein A-I anti-tumor activity targets cancer cell metabolism Research Paper

Maryam Zamanian-Daryoush, Daniel J. Lindner, Jennifer Buffa, Banu Gopalan, Jie Na, Stanley L. Hazen, Joseph A. DiDonato

Published Apr 27, 2020 · Vol. 11, No. 19 · pp. 1777-1796

Keywords: cancer, apolipoprotein A-I, cholesterol, mevalonate pathway, de novo serine synthesis pathway

Nucleolin represses transcription of the androgen receptor gene through a G-quadruplex Research Paper

Cindy K. Miranti, Sara Moore, Yongeun Kim, Venkateshwar Reddy Chappeta, Kui Wu, Biswanath De, Vijay Gokhale, Laurence H. Hurley, Elsa M. Reyes-Reyes

Published Apr 26, 2020 · Vol. 11, No. 19 · pp. 1758-1776

Keywords: prostate cancer, androgen receptor, nucleolin, gene repression, G-quadruplex

Blood-based next-generation sequencing analysis of neuroendocrine neoplasms Research Paper

Katerina Zakka, Rebecca Nagy, Leylah Drusbosky, Mehmet Akce, Christina Wu, Olatunji B. Alese, Bassel F. El-Rayes, Pashtoon Murtaza Kasi, Kabir Mody, Jason Starr, Walid L. Shaib

Published Apr 26, 2020 · Vol. 11, No. 19 · pp. 1749-1757

Keywords: neuroendocrine neoplasm, neuroendocrine tumor, neuroendocrine carcinoma, next-generation sequencing, circulating tumor DNA

Aberrant epigenetic silencing of neuronatin is a frequent event in human osteosarcoma Research Paper

Haleema Saeed, Sayantani Sinha, Christine Mella, Jeffrey S. Kuerbitz, Monica L. Cales, Mark A. Steele, Jennifer Stanke, Derek Damron, Fayez Safadi, Steven J. Kuerbitz

Published Apr 22, 2020 · Vol. 11, No. 20 · pp. 1876-1893

Keywords: osteosarcoma, DNA methylation, neuronatin, tumor suppressor genes

Nutlin-3a suppresses poly (ADP-ribose) polymerase 1 by mechanisms different from conventional PARP1 suppressors in a human breast cancer cell line Research Paper

Masaki Kobayashi, Yuka Ishizaki, Mika Owaki, Yoko Matsumoto, Yuri Kakiyama, Shunsuke Hoshino, Ryoma Tagawa, Yuka Sudo, Naoyuki Okita, Kazunori Akimoto, Yoshikazu Higami

Published Apr 22, 2020 · Vol. 11, No. 18 · pp. 1653-1665

Keywords: nutlin-3a, PARP1, breast cancer, proteasomal degradation, autoPARylation

Aberrant epigenetic silencing of neuronatin is a frequent event in human osteosarcoma Research Paper

Haleema Saeed, Sayantani Sinha, Christine Mella, Jeffrey S. Kuerbitz, Monica L. Cales, Mark A. Steele, Jennifer Stanke, Derek Damron, Fayez Safadi, Steven J. Kuerbitz

Published Apr 22, 2020

Keywords: osteosarcoma, DNA methylation, neuronatin, tumor suppressor genes

The human papillomavirus confers radiosensitivity in oropharyngeal cancer cells by enhancing DNA double strand break Research Paper

Mei Zhang, Angela M. Hong

Published Apr 21, 2020 · Vol. 11, No. 16 · pp. 1417-1426

Keywords: radiosensitivity, oropharyngeal cancer, human papillomavirus, double-strand break, radiobiology

Knock-down of the TIM/TIPIN complex promotes apoptosis in melanoma cells Research Paper

Abhijit Chakraborty, Faisal Aziz, Eunmiri Roh, Le Thi My Le, Raja Dey, Tianshun Zhang, Moeez G. Rathore, Aalekhya Sharma Biswas, Ann M. Bode, Zigang Dong

Published Apr 17, 2020 · Vol. 11, No. 20 · pp. 1846-1861

Keywords: TIMELESS, TIPIN, apoptosis, xenograft, Cryo-EM

Association of germline genetic variants with TMPRSS2-ERG fusion status in prostate cancer Research Paper

Indu Kohaar, Qiyuan Li, Yongmei Chen, Lakshmi Ravindranath, Denise Young, Amina Ali, Isabell A. Sesterhenn, Inger L. Rosner, Jennifer Cullen, Shiv Srivastava, Matthew Freedman, Gyorgy Petrovics

Published Apr 14, 2020 · Vol. 11, No. 15 · pp. 1321-1333

Keywords: prostate cancer, TMPRSS2-ERG, molecular subtype, ERG fusion, SNP

Pirfenidone anti-fibrotic effects are partially mediated by the inhibition of MUC1 bioactivation Research Paper

Beatriz Ballester, Javier Milara, Julio Cortijo

Published Apr 14, 2020 · Vol. 11, No. 15 · pp. 1306-1320

Keywords: pirfenidone, idiopathic pulmonary fibrosis, MUC1, transforming growth factor beta-1, fibroblasts

Proteomic analysis of combined IGF1 receptor targeted therapy and chemotherapy identifies signatures associated with survival in breast cancer patients Research Paper

Tali Sinai-Livne, Metsada Pasmanik-Chor, Zoya Cohen, Ilan Tsarfaty, Haim Werner, Raanan Berger

Published Apr 13, 2020 · Vol. 11, No. 17 · pp. 1515-1530

Keywords: insulin-like growth factor-1 (IGF1), IGF1 receptor (IGF1R), targeted therapy, breast cancer, proteomic analysis

Does breast carcinoma belong to the Lynch syndrome tumor spectrum? – Somatic mutational profiles vs. ovarian and colorectal carcinomas Research Paper

Noora K. Porkka, Alisa Olkinuora, Teijo Kuopio, Maarit Ahtiainen, Samuli Eldfors, Henrikki Almusa, Jukka-Pekka Mecklin, Päivi Peltomäki

Published Apr 7, 2020 · Vol. 11, No. 14 · pp. 1244-1256

Keywords: Lynch syndrome, breast carcinoma, MSI, DNA mismatch repair, somatic mutation

Inhibition of SYK kinase does not confer a pro-proliferative or pro-invasive phenotype in breast epithelium or breast cancer cells Research Paper

David J. Lamb, Aleksander Rust, Albin Rudisch, Tobias Glüxam, Nathalie Harrer, Herwig Machat, Ingrid Christ, Florian Colbatzky, Andreas Wernitznig, Annika Osswald, Wolfgang Sommergruber

Published Apr 7, 2020 · Vol. 11, No. 14 · pp. 1257-1272

Keywords: SYK inhibitor, breast carcinoma, 3D culture, murine mammary gland, proliferation

Investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish Research Paper

Hyejeong Rosemary Kim, Kirankumar Santhakumar, Eleanor Markham, Davide Baldera, David Greenald, Helen E. Bryant, Sherif F. El-Khamisy, Fredericus J. van Eeden

Published Mar 31, 2020 · Vol. 11, No. 13 · pp. 1109-1130

Keywords: Hif, Vhl, DNA repair, apoptosis, chemo/radio-resistance

Transcriptional regulation of HSPB1 by Friend leukemia integration-1 factor modulates radiation and temozolomide resistance in glioblastoma Priority Research Paper

Yetirajam Rajesh, Angana Biswas, Payel Banik, Ipsita Pal, Subhayan Das, Sachin A. Borkar, Hardik Sardana, Abhijit Saha, Swadesh K. Das, Luni Emdad, Paul B. Fisher, Mahitosh Mandal

Published Mar 31, 2020 · Vol. 11, No. 13 · pp. 1097-1108

Keywords: HSPB1, RNAseq, Fli-1, radioresistant GBM, temozolomide resistant GBM

Expression of a germline variant in the N-terminal domain of the human DNA glycosylase NTHL1 induces cellular transformation without impairing enzymatic function or substrate specificity Priority Research Paper

Carolyn G. Marsden, Pawel Jaruga, Erdem Coskun, Robyn L. Maher, David S. Pederson, Miral Dizdaroglu, Joann B. Sweasy

Published Mar 27, 2020 · Vol. 11, No. 24 · pp. 2262-2272

Keywords: NTHL1, cellular transformation, germline variant, base excision repair

hPCL3S promotes proliferation and migration of androgen-independent prostate cancer cells Research Paper

Souhila Abdelfettah, Gaylor Boulay, Marion Dubuissez, Nathalie Spruyt, Sara P. Garcia, Shruthi Rengarajan, Ingrid Loison, Xavier Leroy, Miguel N. Rivera, Dominique Leprince

Published Mar 24, 2020 · Vol. 11, No. 12 · pp. 1051-1074

Keywords: hPCL3S, PHF19, PRC2, β-catenin, prostate cancer

Early prediction of resistance to tyrosine kinase inhibitors by plasma monitoring of EGFR mutations in NSCLC: a new algorithm for patient selection and personalized treatment Research Paper

Fiamma Buttitta, Lara Felicioni, Alessia Di Lorito, Alessio Cortellini, Luciana Irtelli, Davide Brocco, Pietro Di Marino, Donatella Traisci, Nicola D’Ostilio, Alessandra Di Paolo, Francesco Malorgio, Pasquale Assalone, Sonia Di Felice, Francesca Fabbri, Giovanni Cianci, Michele De Tursi, Antonio Marchetti

Published Mar 17, 2020 · Vol. 11, No. 11 · pp. 982-991

Keywords: epidermal growth factor receptor (EGFR), tyrosine-kinase Inhibitors, circulating tumor-DNA (ct-DNA), massive parallel sequencing (MPS), resistance-inducing mutation

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Profiling the circulating mRNA transcriptome in human liver disease Research Paper

Panaxynol, a bioactive component of American ginseng, targets macrophages and suppresses colitis in mice Priority Research Paper

Apolipoprotein A-I anti-tumor activity targets cancer cell metabolism Research Paper

Nucleolin represses transcription of the androgen receptor gene through a G-quadruplex Research Paper

Blood-based next-generation sequencing analysis of neuroendocrine neoplasms Research Paper

Aberrant epigenetic silencing of neuronatin is a frequent event in human osteosarcoma Research Paper

Nutlin-3a suppresses poly (ADP-ribose) polymerase 1 by mechanisms different from conventional PARP1 suppressors in a human breast cancer cell line Research Paper

Aberrant epigenetic silencing of neuronatin is a frequent event in human osteosarcoma Research Paper

The human papillomavirus confers radiosensitivity in oropharyngeal cancer cells by enhancing DNA double strand break Research Paper

Knock-down of the TIM/TIPIN complex promotes apoptosis in melanoma cells Research Paper

Association of germline genetic variants with TMPRSS2-ERG fusion status in prostate cancer Research Paper

Pirfenidone anti-fibrotic effects are partially mediated by the inhibition of MUC1 bioactivation Research Paper

Proteomic analysis of combined IGF1 receptor targeted therapy and chemotherapy identifies signatures associated with survival in breast cancer patients Research Paper

Does breast carcinoma belong to the Lynch syndrome tumor spectrum? – Somatic mutational profiles vs. ovarian and colorectal carcinomas Research Paper

Inhibition of SYK kinase does not confer a pro-proliferative or pro-invasive phenotype in breast epithelium or breast cancer cells Research Paper

Investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish Research Paper

Transcriptional regulation of HSPB1 by Friend leukemia integration-1 factor modulates radiation and temozolomide resistance in glioblastoma Priority Research Paper

Expression of a germline variant in the N-terminal domain of the human DNA glycosylase NTHL1 induces cellular transformation without impairing enzymatic function or substrate specificity Priority Research Paper

hPCL3S promotes proliferation and migration of androgen-independent prostate cancer cells Research Paper

Early prediction of resistance to tyrosine kinase inhibitors by plasma monitoring of EGFR mutations in NSCLC: a new algorithm for patient selection and personalized treatment Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Profiling the circulating mRNA transcriptome in human liver disease Research Paper

Panaxynol, a bioactive component of American ginseng, targets macrophages and suppresses colitis in mice Priority Research Paper

Apolipoprotein A-I anti-tumor activity targets cancer cell metabolism Research Paper

Nucleolin represses transcription of the androgen receptor gene through a G-quadruplex Research Paper

Blood-based next-generation sequencing analysis of neuroendocrine neoplasms Research Paper

Aberrant epigenetic silencing of neuronatin is a frequent event in human osteosarcoma Research Paper

Nutlin-3a suppresses poly (ADP-ribose) polymerase 1 by mechanisms different from conventional PARP1 suppressors in a human breast cancer cell line Research Paper

Aberrant epigenetic silencing of neuronatin is a frequent event in human osteosarcoma Research Paper

The human papillomavirus confers radiosensitivity in oropharyngeal cancer cells by enhancing DNA double strand break Research Paper

Knock-down of the TIM/TIPIN complex promotes apoptosis in melanoma cells Research Paper

Association of germline genetic variants with TMPRSS2-ERG fusion status in prostate cancer Research Paper

Pirfenidone anti-fibrotic effects are partially mediated by the inhibition of MUC1 bioactivation Research Paper

Proteomic analysis of combined IGF1 receptor targeted therapy and chemotherapy identifies signatures associated with survival in breast cancer patients Research Paper

Does breast carcinoma belong to the Lynch syndrome tumor spectrum? – Somatic mutational profiles vs. ovarian and colorectal carcinomas Research Paper

Inhibition of SYK kinase does not confer a pro-proliferative or pro-invasive phenotype in breast epithelium or breast cancer cells Research Paper

Investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish Research Paper

Transcriptional regulation of HSPB1 by Friend leukemia integration-1 factor modulates radiation and temozolomide resistance in glioblastoma Priority Research Paper

Expression of a germline variant in the N-terminal domain of the human DNA glycosylase NTHL1 induces cellular transformation without impairing enzymatic function or substrate specificity Priority Research Paper

hPCL3S promotes proliferation and migration of androgen-independent prostate cancer cells Research Paper

Early prediction of resistance to tyrosine kinase inhibitors by plasma monitoring of EGFR mutations in NSCLC: a new algorithm for patient selection and personalized treatment Research Paper