The Oncosearch | Oncotarget

ABT199/venetoclax potentiates the cytotoxicity of alkylating agents and fludarabine in acute myeloid leukemia cells Research Paper

Benigno C. Valdez, David Murray, Bin Yuan, Yago Nieto, Uday Popat, Borje S. Andersson

Published Feb 2, 2022 · Vol. 13, No. 1 · pp. 319-330

Keywords: ABT199/venetoclax, busulfan, cyclophosphamide, fludarabine, acute myeloid leukemia

Positive predictive value of ERBB2 copy number gain by tissue or circulating tumor DNA next-generation sequencing across advanced cancers Research Paper

Ami N. Shah, Ashwin Sunderraj, Brian Finkelman, Sharlene H. See, Andrew A. Davis, Lorenzo Gerratana, Firas Wehbe, Neelima Katam, Deva Mahalingam, William J. Gradishar, Amir Behdad, Luis Blanco, Massimo Cristofanilli

Published Jan 26, 2022 · Vol. 13, No. 1 · pp. 273-280

Keywords: ERBB2, HER2, next-generation sequencing, copy number gain, circulating tumor DNA

Common cancer treatments targeting DNA double strand breaks affect long-term memory and relate to immediate early gene expression in a sex-dependent manner Research Paper

Sydney Weber Boutros, Destine Krenik, Sarah Holden, Vivek K. Unni, Jacob Raber

Published Jan 14, 2022 · Vol. 13, No. 1 · pp. 198-213

Keywords: amifostine, etoposide, double strand breaks, memory, sex

Chimeric chromosome landscapes of human somatic cell cultures show dependence on stress and regulation of genomic repeats by CGGBP1 Research Paper

Subhamoy Datta, Manthan Patel, Sukesh Kashyap, Divyesh Patel, Umashankar Singh

Published Dec 24, 2021 · Vol. 13, No. 1 · pp. 136-155

Keywords: CGGBP1, non-homologous chromosomal chimeras, methylation, heat stress, repeats

Chimeric chromosome landscapes of human somatic cell cultures show dependence on stress and regulation of genomic repeats by CGGBP1 Research Paper

Subhamoy Datta, Manthan Patel, Sukesh Kashyap, Divyesh Patel, Umashankar Singh

Published Dec 24, 2021

Keywords: CGGBP1, non-homologous chromosomal chimeras, methylation, heat stress, repeats

Synthesis of a novel nanobioconjugate for targeted photodynamic therapy of colon cancer enhanced with cannabidiol Research Paper

Nkune Williams Nkune, Cherie Ann Kruger, Heidi Abrahamse

Published Dec 23, 2021 · Vol. 13, No. 1 · pp. 156-172

Keywords: cannabidiol, photodynamic therapy, colorectal cancer, nanoparticles, photosensitizer

Transcriptomics reveals in vivo efficacy of PARP inhibitor combinatorial synergy with platinum-based chemotherapy in human non-small cell lung carcinoma models Research Paper

Lindsay R. Stolzenburg, Barrett Ainsworth, Bridget Riley-Gillis, Tibor Pakozdi, Areej Ammar, Paul A. Ellis, Julie L. Wilsbacher, Cyril Y. Ramathal

Published Dec 17, 2021 · Vol. 13, No. 1 · pp. 1-12

Keywords: PARP inhibitor, veliparib, cisplatin, transcriptomics, NSCLC

RASAL2 suppresses the proliferative and invasive ability of PC3 prostate cancer cells Research Paper

Krishma Tailor, Joseph Paul, Somiranjan Ghosh, Namita Kumari, Bernard Kwabi-Addo

Published Dec 15, 2021 · Vol. 12, No. 26 · pp. 2489-2499

Keywords: RASAL2, Ras-protooncogene, prostate cancer, TNFα signal, DNA methylation

Circulating low density neutrophils of breast cancer patients are associated with their worse prognosis due to the impairment of T cell responses Research Paper

Diana P. Saraiva, Bruna F. Correia, Rute Salvador, Nídia de Sousa, António Jacinto, Sofia Braga, M. Guadalupe Cabral

Published Nov 15, 2021 · Vol. 12, No. 24 · pp. 2388-2403

Keywords: breast cancer, chemotherapy response, tumor-associated neutrophils, low density neutrophils, biomarker

Molecular characterization of Kita-Kyushu lung cancer antigen (KK-LC-1) expressing carcinomas Research Paper

Robert Hsu, Yasmine Baca, Joanne Xiu, Rongfu Wang, J. Nicholas Bodor, Chul Kim, Hina Khan, Hirva Mamdani, Misako Nagasaka, Sonam Puri, Stephen V. Liu, W. Michael Korn, Jorge J. Nieva

Published Nov 13, 2021 · Vol. 12, No. 25 · pp. 2449-2458

Keywords: lung cancer, tumor microenvironment, diagnostic biomarkers, biomarkers for immunotherapy, cancer testis antigen

Correction: Cdc6 contributes to cisplatin-resistance by activation of ATR-Chk1 pathway in bladder cancer cells Correction

Sansan Chen, Xinglu Chen, Gui’e Xie, Yue He, Daoyu Yan, Dianpeng Zheng, Shi Li, Xinyang Fu, Yeping Li, Xiang Pang, Zhiming Hu, Hongwei Li, Wanlong Tan, Jinlong Li

Published Oct 26, 2021

Comparison of MET gene amplification analysis by next-generation sequencing and fluorescence in situ hybridization Research Paper

Christina Schmitt, Anna-Alice Schulz, Ria Winkelmann, Kevin Smith, Peter J. Wild, Melanie Demes

Published Oct 5, 2021 · Vol. 12, No. 22 · pp. 2273-2282

Keywords: next-generation sequencing (NGS), non-small cell lung cancer (NSCLC), fluorescence in situ hybridization (FISH), MET amplification, routine diagnostics

Emerging approaches of wound healing in experimental models of high-grade oral mucositis induced by anticancer therapy Review

Ana Chor, Maria Adriana Skeff, Christina Takiya, Raquel Gonçalves, Marcos Dias, Marcos Farina, Leonardo R. Andrade, Valeria de Mello Coelho

Published Oct 1, 2021 · Vol. 12, No. 22 · pp. 2283-2299

Keywords: oral mucositis, inflammation, regeneration, polymers, tissue engineering

ATR inhibition reverses the resistance of homologous recombination deficient MGMT^low/MMR^proficient cancer cells to temozolomide Priority Research Paper

Lara H. El Touny, Curtis Hose, John Connelly, Erik Harris, Anne Monks, Angie B. Dull, Deborah F. Wilsker, Melinda G. Hollingshead, Michelle Gottholm-Ahalt, Sergio Y. Alcoser, Michael E. Mullendore, Ralph E. Parchment, James H. Doroshow, Beverly A. Teicher, Annamaria Rapisarda

Published Sep 28, 2021 · Vol. 12, No. 21 · pp. 2114-2130

Keywords: TMZ, MMR, ATR, HR, REV3L

Hepatitis B x antigen (HBx) is an important therapeutic target in the pathogenesis of hepatocellular carcinoma Research Perspective

Arvin Medhat, Alla Arzumanyan, Mark A. Feitelson

Published Sep 11, 2021 · Vol. 12, No. 24 · pp. 2421-2433

Keywords: chronic liver disease, hepatocellular carcinoma, HBx, functional cure, epigenetic

Selinexor, a selective inhibitor of nuclear export, enhances the anti-tumor activity of olaparib in triple negative breast cancer regardless of BRCA1 mutation status Research Paper

Hélène Marijon, Sigal Gery, Hua Chang, Yosef Landesman, Sharon Shacham, Dhong Hyun Lee, Aimery de Gramont, Harold Phillip Koeffler

Published Aug 10, 2021 · Vol. 12, No. 18 · pp. 1749-1762

Keywords: selinexor, XPO1, olaparib, triple negative breast cancer, BRCA1

Pim kinase inhibitor co-treatment decreases alternative non-homologous end-joining DNA repair and genomic instability induced by topoisomerase 2 inhibitors in cells with FLT3 internal tandem duplication Research Paper

Mario Scarpa, Shivani Kapoor, Eric S. Tvedte, Kshama A. Doshi, Ying S. Zou, Prerna Singh, Jonelle K. Lee, Aditi Chatterjee, Moaath K. Mustafa Ali, Robin E. Bromley, Julie C. Dunning Hotopp, Feyruz V. Rassool, Maria R. Baer

Published Aug 2, 2021 · Vol. 12, No. 18 · pp. 1763-1779

Keywords: FLT3 internal tandem duplication, Pim kinase, alternative non-homologous end-joining DNA repair, genomic instability, topoisomerase 2 inhibitors

Inhibition of the MAP2K7-JNK pathway with 5Z-7-oxozeaenol induces apoptosis in T-cell acute lymphoblastic leukemia Research Paper

Taylor J. Chen, Wa Du, Jacob J. Junco, Cory Seth Bridges, Ye Shen, Monica Puppi, Karen R. Rabin, H. Daniel Lacorazza

Published Jul 31, 2021 · Vol. 12, No. 18 · pp. 1787-1801

Keywords: T-ALL, MAP2K7, 5z-7-oxozeaenol

Diverse transcriptional regulation and functional effects revealed by CRISPR/Cas9-directed epigenetic editing Research Paper

Miguel Vizoso, Jacco van Rheenen

Published Jul 29, 2021 · Vol. 12, No. 17 · pp. 1651-1662

Keywords: targeted DNA methylation, CRISPR/Cas9-based system, IGFBP2, epithelial-to-mesenchymal transition

Epigenetic signatures differentiate uterine and soft tissue leiomyosarcoma Research Paper

Nesrin M. Hasan, Anup Sharma, Nensi M. Ruzgar, Hari Deshpande, Kelly Olino, Sajid Khan, Nita Ahuja

Published Jul 21, 2021 · Vol. 12, No. 16 · pp. 1566-1579

Keywords: leiomyosarcoma, epigenetics, DNA methylation, gene expression, uterine leiomyosarcoma

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ABT199/venetoclax potentiates the cytotoxicity of alkylating agents and fludarabine in acute myeloid leukemia cells Research Paper

Positive predictive value of ERBB2 copy number gain by tissue or circulating tumor DNA next-generation sequencing across advanced cancers Research Paper

Common cancer treatments targeting DNA double strand breaks affect long-term memory and relate to immediate early gene expression in a sex-dependent manner Research Paper

Chimeric chromosome landscapes of human somatic cell cultures show dependence on stress and regulation of genomic repeats by CGGBP1 Research Paper

Chimeric chromosome landscapes of human somatic cell cultures show dependence on stress and regulation of genomic repeats by CGGBP1 Research Paper

Synthesis of a novel nanobioconjugate for targeted photodynamic therapy of colon cancer enhanced with cannabidiol Research Paper

Transcriptomics reveals in vivo efficacy of PARP inhibitor combinatorial synergy with platinum-based chemotherapy in human non-small cell lung carcinoma models Research Paper

RASAL2 suppresses the proliferative and invasive ability of PC3 prostate cancer cells Research Paper

Circulating low density neutrophils of breast cancer patients are associated with their worse prognosis due to the impairment of T cell responses Research Paper

Molecular characterization of Kita-Kyushu lung cancer antigen (KK-LC-1) expressing carcinomas Research Paper

Correction: Cdc6 contributes to cisplatin-resistance by activation of ATR-Chk1 pathway in bladder cancer cells Correction

Comparison of MET gene amplification analysis by next-generation sequencing and fluorescence in situ hybridization Research Paper

Emerging approaches of wound healing in experimental models of high-grade oral mucositis induced by anticancer therapy Review

ATR inhibition reverses the resistance of homologous recombination deficient MGMT^low/MMR^proficient cancer cells to temozolomide Priority Research Paper

Hepatitis B x antigen (HBx) is an important therapeutic target in the pathogenesis of hepatocellular carcinoma Research Perspective

Selinexor, a selective inhibitor of nuclear export, enhances the anti-tumor activity of olaparib in triple negative breast cancer regardless of BRCA1 mutation status Research Paper

Pim kinase inhibitor co-treatment decreases alternative non-homologous end-joining DNA repair and genomic instability induced by topoisomerase 2 inhibitors in cells with FLT3 internal tandem duplication Research Paper

Inhibition of the MAP2K7-JNK pathway with 5Z-7-oxozeaenol induces apoptosis in T-cell acute lymphoblastic leukemia Research Paper

Diverse transcriptional regulation and functional effects revealed by CRISPR/Cas9-directed epigenetic editing Research Paper

Epigenetic signatures differentiate uterine and soft tissue leiomyosarcoma Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

ABT199/venetoclax potentiates the cytotoxicity of alkylating agents and fludarabine in acute myeloid leukemia cells Research Paper

Positive predictive value of ERBB2 copy number gain by tissue or circulating tumor DNA next-generation sequencing across advanced cancers Research Paper

Common cancer treatments targeting DNA double strand breaks affect long-term memory and relate to immediate early gene expression in a sex-dependent manner Research Paper

Chimeric chromosome landscapes of human somatic cell cultures show dependence on stress and regulation of genomic repeats by CGGBP1 Research Paper

Chimeric chromosome landscapes of human somatic cell cultures show dependence on stress and regulation of genomic repeats by CGGBP1 Research Paper

Synthesis of a novel nanobioconjugate for targeted photodynamic therapy of colon cancer enhanced with cannabidiol Research Paper

Transcriptomics reveals in vivo efficacy of PARP inhibitor combinatorial synergy with platinum-based chemotherapy in human non-small cell lung carcinoma models Research Paper

RASAL2 suppresses the proliferative and invasive ability of PC3 prostate cancer cells Research Paper

Circulating low density neutrophils of breast cancer patients are associated with their worse prognosis due to the impairment of T cell responses Research Paper

Molecular characterization of Kita-Kyushu lung cancer antigen (KK-LC-1) expressing carcinomas Research Paper

Correction: Cdc6 contributes to cisplatin-resistance by activation of ATR-Chk1 pathway in bladder cancer cells Correction

Comparison of MET gene amplification analysis by next-generation sequencing and fluorescence in situ hybridization Research Paper

Emerging approaches of wound healing in experimental models of high-grade oral mucositis induced by anticancer therapy Review

ATR inhibition reverses the resistance of homologous recombination deficient MGMTlow/MMRproficient cancer cells to temozolomide Priority Research Paper

Hepatitis B x antigen (HBx) is an important therapeutic target in the pathogenesis of hepatocellular carcinoma Research Perspective

Selinexor, a selective inhibitor of nuclear export, enhances the anti-tumor activity of olaparib in triple negative breast cancer regardless of BRCA1 mutation status Research Paper

Pim kinase inhibitor co-treatment decreases alternative non-homologous end-joining DNA repair and genomic instability induced by topoisomerase 2 inhibitors in cells with FLT3 internal tandem duplication Research Paper

Inhibition of the MAP2K7-JNK pathway with 5Z-7-oxozeaenol induces apoptosis in T-cell acute lymphoblastic leukemia Research Paper

Diverse transcriptional regulation and functional effects revealed by CRISPR/Cas9-directed epigenetic editing Research Paper

Epigenetic signatures differentiate uterine and soft tissue leiomyosarcoma Research Paper

ATR inhibition reverses the resistance of homologous recombination deficient MGMT^low/MMR^proficient cancer cells to temozolomide Priority Research Paper