The Oncosearch | Oncotarget

Correction: β2-spectrin depletion impairs DNA damage repair Correction

Nobuo Horikoshi, Raj K. Pandita, Kalpana Mujoo, Shashank Hambarde, Dharmendra Sharma, Abid R. Mattoo, Sharmistha Chakraborty, Vijaya Charaka, Clayton R. Hunt, Tej K. Pandita

Published Apr 25, 2026 · Vol. 17, No. 1 · pp. 210-211

Epigenetic dysregulation and biological function of PDX1 in prostate cancer Research Paper

Tayo A. Adeyika, Anju Datturgi, Yehnara Ettinoffe, Somiranjan Ghosh, Christopher Albanese, Bernard Kwabi-Addo

Published Apr 1, 2026 · Vol. 17, No. 1 · pp. 157-172

Keywords: PDX1, DNA methylation prostate cancer, shRNA knockdown, over-expression, glucose

Bibliometric mapping of glioma classification research through main path, key route, and K-core analyses Review

Kayode Ahmed, Juan E. Núñez-Ríos

Published Apr 1, 2026 · Vol. 17, No. 1 · pp. 90-118

Keywords: glioma research, social network analysis, socio-clinical domains, web of science, networks

Anti-DNA virus agent cidofovir - loaded green synthesized cerium oxide nanoparticles (Nanoceria): Nucleic acids (DNA and RNA) binding affinity and cytotoxicity effects Research Paper

Nahid Shahabadi, Saba Zendehcheshm, Fatemeh Khademi, Mohammad Mahdavi

Published Oct 23, 2025 · Vol. 16, No. 1 · pp. 768-789

Keywords: CeO₂ NPs, green synthesis, DNA interaction, RNA interaction, cytotoxicity

ACTM-838, a novel systemically delivered bacterial immunotherapy that enriches in solid tumors and delivers IL-15/IL-15Rα and STING payloads to engage innate and adaptive immunity in the TME and enable a durable anti-tumor immune response Research Paper

Kyle R. Cron, Ping Fang, Oanh Pham, Julie Janes, John Brandenburg, William Lu, Jonathan Zhu, Bret Peterson, Sara Tribble, Haixing Kehoe, Anastasia Makarova, Alex Iannello, Jean Chan, Justin Skoble, Hailey He, Chris Rae, Christopher D. Thanos, Akshata R. Udyavar

Published Oct 2, 2025 · Vol. 16, No. 1 · pp. 721-740

Keywords: tumor microenvironment, bacterial vector, myeloid cells, STING, IL-15

In vivo manipulation of the protein homeostasis network in rhabdomyosarcoma Research Paper

Kristen Kwong, Yue Pan, Jacqueline Morales, Matthew Watson, David V. Allegakoen, Alex G. Lee, Trever G. Bivona, Peter Wipf, Christopher J. Guerriero, Jeffrey L. Brodsky, Amit J. Sabnis

Published Aug 23, 2025 · Vol. 16, No. 1 · pp. 681-696

Keywords: protein homeostasis, rhabdomyosarcoma, unfolded protein response, preclinical therapeutics, p97

Clinical and analytical validation of MI Cancer Seek^®, a companion diagnostic whole exome and whole transcriptome sequencing-based comprehensive molecular profiling assay Research Paper

Valeriy Domenyuk, Kasey Benson, Peggy Carter, Daniel Magee, Jian Zhang, Nitin Bhardwaj, Hongseok Tae, James Wacker, Foram Rathi, Siobhan Miick, Aastha Kohli, Joshua Carroll, Lori Cuyugan, Evelyn Perez, Wayeesha Zhang, John Collins, Patrick Kennedy, Jeremy Ellis, Adam Stark, Andrey Loskutov, Brittany Cuttone, Blake Taylor, Rebecca Feldman, Jeff Swenson, David Bryant, Robert Hahn-Lowry, Raunaq Kaushal, Jennifer R. Ribeiro, Jim Abraham, Milan Radovich, George W. Sledge, Matthew Oberley, David Spetzler

Published Aug 6, 2025 · Vol. 16, No. 1 · pp. 642-659

Keywords: companion diagnostic, molecular profiling, solid tumors, precision oncology, next-generation sequencing

Genetic characteristics of blastic plasmacytoid dendritic cell neoplasm: A single institution experience Research Paper

Fei Fei, Milhan Telatar, Vanina Tomasian, Lisa Chang, Olga Danilova, Javier Arias-Stella, Raju Pillai, Lorinda Soma, Parastou Tizro, Pamela S. Becker, Anthony S. Stein, Guido Marcucci, Michelle Afkhami

Published Jun 7, 2025 · Vol. 16, No. 1 · pp. 495-507

Keywords: Blastic plasmacytoid dendritic cell neoplasm (BPDCN), Next-generation sequencing (NGS), CCDC50

Beyond DNA damage response: Immunomodulatory attributes of CHEK2 in solid tumors Review

Helen Qian, Heba Ali, Vivekanudeep Karri, Justin T. Low, David M. Ashley, Amy B. Heimberger, Lucy A. Godley, Adam M. Sonabend, Crismita Dmello

Published Jun 5, 2025 · Vol. 16, No. 1 · pp. 445-453

Keywords: CHEK2, immune checkpoint inhibitors, immunomodulation

Durable complete response in leptomeningeal disease of EGFR mutated non-small cell lung cancer to amivantamab, an EGFR-MET receptor bispecific antibody, after progressing on osimertinib Research Paper

Jinah Kim, Liam Il-Young Chung, Horyun Choi, Yoonhee Choi, Maria Jose Aguilera Chuchuca, Youjin Oh, Young Kwang Chae

Published May 21, 2025 · Vol. 16, No. 1 · pp. 411-418

Keywords: amivantamab, monotherapy, rare EGFR mutation, NSCLC, leptomeningeal disease

Retraction: Inhibition of protein phosphatase 2A with a small molecule LB100 radiosensitizes nasopharyngeal carcinoma xenografts by inducing mitotic catastrophe and blocking DNA damage repair Retraction

Peng Lv, Yue Wang, Jie Ma, Zheng Wang, Jing-Li Li, Christopher S. Hong, Zhengping Zhuang, Yi-Xin Zeng

Published May 17, 2025 · Vol. 16, No. 1 · pp. 361-361

Cigarette smoke and decreased DNA repair by Xeroderma Pigmentosum Group C use a double hit mechanism for epithelial cell lung carcinogenesis Research Paper

Nawar Al Nasrallah, Bowa Lee, Benjamin M. Wiese, Marie N. Karam, Elizabeth A. Mickler, Huaxin Zhou, Nicki Paolelli, Robert S. Stearman, Mark W. Geraci, Catherine R. Sears

Published May 9, 2025 · Vol. 16, No. 1 · pp. 396-409

Keywords: DNA repair, DNA damage, lung adenocarcinoma, squamous cell carcinoma, Xeroderma Pigmentosum Group C (XPC)

Targeting PCNA/AR interaction inhibits AR-mediated signaling in castration resistant prostate cancer cells Research Paper

Shan Lu, Zhongyun Dong

Published May 8, 2025 · Vol. 16, No. 1 · pp. 383-395

Keywords: PCNA, androgen receptor, PCNA inhibitors, AR splicing variants, CRPC

PRDX1 protects ATM from arsenite-induced proteotoxicity and maintains its stability during DNA damage signaling Research Paper

Reem Ali, Mashael Algethami, Amera Sheha, Shatha Alqahtani, Ahmad Altayyar, Ayat Lashen, Emad Rakha, Abdallah Alhaj Sulaiman, Srinivasan Madhusudan, Dindial Ramotar

Published May 3, 2025 · Vol. 16, No. 1 · pp. 362-378

Keywords: redox signaling, homologous recombination, protein interaction, cell cycle, protein modification

Analytical validation of a circulating tumor DNA assay using PhasED-Seq technology for detecting residual disease in B-cell malignancies Research Paper

Nina Klimova, Sandra Close, David M. Kurtz, Richard D. Hockett, Laura Hyland

Published May 2, 2025 · Vol. 16, No. 1 · pp. 329-336

Keywords: MRD, ctDNA, PhasED-Seq, CLARITY, residual disease

Association between two single nucleotide polymorphisms of the Prostaglandin-Endoperoxide Synthase 1 and 2 genes and cell proliferative prostatic diseases in Lebanon Research Paper

Brock J. Sheehan, Bryson Edwards, Ivanna Soto Medrano, Mohammed A. El-Saidi, Wissam R. Zaidan, Asmahan A. El-Ezzi, Ruhul H. Kuddus

Published Mar 31, 2025 · Vol. 16, No. 1 · pp. 262-272

Keywords: PTGS1 and PTGS2 genes, COX-1 and COX-2 isozymes, single nucleotide polymorphism association study, prostate cancer, benign prostate hyperplasia (BPH)

Imipridones ONC201/ONC206 + RT/TMZ triple (IRT) therapy reduces intracranial tumor burden, prolongs survival in orthotopic IDH-WT GBM mouse model, and suppresses MGMT Research Paper

Lanlan Zhou, Leiqing Zhang, Jun Zhang, Laura Jinxuan Wu, Shengliang Zhang, Andrew George, Marina Hahn, Howard P. Safran, Clark C. Chen, Attila A. Seyhan, Eric T. Wong, Wafik S. El-Deiry

Published Mar 20, 2025 · Vol. 16, No. 1 · pp. 230-248

Keywords: glioblastoma multiforme, IDH, ONC201, ONC206, MGMT, temozolomide, radiotherapy

NSD2-epigenomic reprogramming and maintenance of plasma cell phenotype in t(4;14) myeloma Research Paper

Andrea Gunnell, Scott T. Kimber, Richard Houlston, Martin Kaiser

Published Mar 16, 2025 · Vol. 16, No. 1 · pp. 220-229

Keywords: myeloma, NSD2, t(4;14), CD38, plasma cell

FGR Src family kinase causes signaling and phenotypic shift mimicking retinoic acid-induced differentiation of leukemic cells Research Paper

Noor Kazim, Wang Peng, Jianbo Yue, Andrew Yen

Published Mar 14, 2025 · Vol. 16, No. 1 · pp. 202-218

Keywords: cancer biology and cell cycle regulation, retinoic acid(RA), FGR Src-family-kinase, cancer differentiation-therapy, leukemia

Signaling pathway dysregulation in breast cancer Review

Dinara Ryspayeva, Attila A. Seyhan, William J. MacDonald, Connor Purcell, Tyler J. Roady, Maryam Ghandali, Nataliia Verovkina, Wafik S. El-Deiry, Martin S. Taylor, Stephanie L. Graff

Published Mar 7, 2025 · Vol. 16, No. 1 · pp. 168-201

Keywords: breast cancer, oncogenic pathways, signal dysregulation in cancer, therapeutic approaches, clinical trials

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

Correction: β2-spectrin depletion impairs DNA damage repair Correction

Epigenetic dysregulation and biological function of PDX1 in prostate cancer Research Paper

Bibliometric mapping of glioma classification research through main path, key route, and K-core analyses Review

Anti-DNA virus agent cidofovir - loaded green synthesized cerium oxide nanoparticles (Nanoceria): Nucleic acids (DNA and RNA) binding affinity and cytotoxicity effects Research Paper

ACTM-838, a novel systemically delivered bacterial immunotherapy that enriches in solid tumors and delivers IL-15/IL-15Rα and STING payloads to engage innate and adaptive immunity in the TME and enable a durable anti-tumor immune response Research Paper

In vivo manipulation of the protein homeostasis network in rhabdomyosarcoma Research Paper

Clinical and analytical validation of MI Cancer Seek^®, a companion diagnostic whole exome and whole transcriptome sequencing-based comprehensive molecular profiling assay Research Paper

Genetic characteristics of blastic plasmacytoid dendritic cell neoplasm: A single institution experience Research Paper

Beyond DNA damage response: Immunomodulatory attributes of CHEK2 in solid tumors Review

Durable complete response in leptomeningeal disease of EGFR mutated non-small cell lung cancer to amivantamab, an EGFR-MET receptor bispecific antibody, after progressing on osimertinib Research Paper

Retraction: Inhibition of protein phosphatase 2A with a small molecule LB100 radiosensitizes nasopharyngeal carcinoma xenografts by inducing mitotic catastrophe and blocking DNA damage repair Retraction

Cigarette smoke and decreased DNA repair by Xeroderma Pigmentosum Group C use a double hit mechanism for epithelial cell lung carcinogenesis Research Paper

Targeting PCNA/AR interaction inhibits AR-mediated signaling in castration resistant prostate cancer cells Research Paper

PRDX1 protects ATM from arsenite-induced proteotoxicity and maintains its stability during DNA damage signaling Research Paper

Analytical validation of a circulating tumor DNA assay using PhasED-Seq technology for detecting residual disease in B-cell malignancies Research Paper

Association between two single nucleotide polymorphisms of the Prostaglandin-Endoperoxide Synthase 1 and 2 genes and cell proliferative prostatic diseases in Lebanon Research Paper

Imipridones ONC201/ONC206 + RT/TMZ triple (IRT) therapy reduces intracranial tumor burden, prolongs survival in orthotopic IDH-WT GBM mouse model, and suppresses MGMT Research Paper

NSD2-epigenomic reprogramming and maintenance of plasma cell phenotype in t(4;14) myeloma Research Paper

FGR Src family kinase causes signaling and phenotypic shift mimicking retinoic acid-induced differentiation of leukemic cells Research Paper

Signaling pathway dysregulation in breast cancer Review

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Correction: β2-spectrin depletion impairs DNA damage repair Correction

Epigenetic dysregulation and biological function of PDX1 in prostate cancer Research Paper

Bibliometric mapping of glioma classification research through main path, key route, and K-core analyses Review

Anti-DNA virus agent cidofovir - loaded green synthesized cerium oxide nanoparticles (Nanoceria): Nucleic acids (DNA and RNA) binding affinity and cytotoxicity effects Research Paper

ACTM-838, a novel systemically delivered bacterial immunotherapy that enriches in solid tumors and delivers IL-15/IL-15Rα and STING payloads to engage innate and adaptive immunity in the TME and enable a durable anti-tumor immune response Research Paper

In vivo manipulation of the protein homeostasis network in rhabdomyosarcoma Research Paper

Clinical and analytical validation of MI Cancer Seek®, a companion diagnostic whole exome and whole transcriptome sequencing-based comprehensive molecular profiling assay Research Paper

Genetic characteristics of blastic plasmacytoid dendritic cell neoplasm: A single institution experience Research Paper

Beyond DNA damage response: Immunomodulatory attributes of CHEK2 in solid tumors Review

Durable complete response in leptomeningeal disease of EGFR mutated non-small cell lung cancer to amivantamab, an EGFR-MET receptor bispecific antibody, after progressing on osimertinib Research Paper

Retraction: Inhibition of protein phosphatase 2A with a small molecule LB100 radiosensitizes nasopharyngeal carcinoma xenografts by inducing mitotic catastrophe and blocking DNA damage repair Retraction

Cigarette smoke and decreased DNA repair by Xeroderma Pigmentosum Group C use a double hit mechanism for epithelial cell lung carcinogenesis Research Paper

Targeting PCNA/AR interaction inhibits AR-mediated signaling in castration resistant prostate cancer cells Research Paper

PRDX1 protects ATM from arsenite-induced proteotoxicity and maintains its stability during DNA damage signaling Research Paper

Analytical validation of a circulating tumor DNA assay using PhasED-Seq technology for detecting residual disease in B-cell malignancies Research Paper

Association between two single nucleotide polymorphisms of the Prostaglandin-Endoperoxide Synthase 1 and 2 genes and cell proliferative prostatic diseases in Lebanon Research Paper

Imipridones ONC201/ONC206 + RT/TMZ triple (IRT) therapy reduces intracranial tumor burden, prolongs survival in orthotopic IDH-WT GBM mouse model, and suppresses MGMT Research Paper

NSD2-epigenomic reprogramming and maintenance of plasma cell phenotype in t(4;14) myeloma Research Paper

FGR Src family kinase causes signaling and phenotypic shift mimicking retinoic acid-induced differentiation of leukemic cells Research Paper

Signaling pathway dysregulation in breast cancer Review

Clinical and analytical validation of MI Cancer Seek^®, a companion diagnostic whole exome and whole transcriptome sequencing-based comprehensive molecular profiling assay Research Paper