The Oncosearch | Oncotarget

Prevalence and spectrum of germline BRCA1 and BRCA2 in a cohort of ovarian cancer patients from the Salento peninsula (Southern Italy): a matter of preventive health Research Paper

Elisabetta De Matteis, Maria Rosaria Tumolo, Paolo Tarantino, Mariangela Ciccarese, Tiziana Grassi, Francesco Bagordo, Maria Rita De Giorgio, Emanuele Rizzo, Graziana Ronzino

Published Feb 15, 2024 · Vol. 15, No. 1 · pp. 134-141

Keywords: ovarian cancer, BRCA1, BRCA2, mutation

Differential expression of Mad2 gene is consequential to the patterns of histone H3 post-translational modifications in its promoter region in human esophageal cancer samples Research Paper

Chongtham Sovachandra Singh, Nabamita Boruah, Atanu Banerjee, Sillarine Kurkalang, Pooja Swargiary, Hughbert Dakhar, Anupam Chatterjee

Published Jan 11, 2024 · Vol. 15, No. 1 · pp. 76-89

Keywords: Mad2 gene, histone methylation, histone acetylation, Rb-phosphorylation, esophageal cancer

ATR inhibition using gartisertib enhances cell death and synergises with temozolomide and radiation in patient-derived glioblastoma cell lines Research Paper

Mathew Lozinski, Nikola A. Bowden, Moira C. Graves, Michael Fay, Bryan W. Day, Brett W. Stringer, Paul A. Tooney

Published Jan 5, 2024 · Vol. 15, No. 1 · pp. 1-18

Keywords: glioblastoma, DNA damage response, ataxia-telangiectasia and rad3-related protein, radiation therapy, temozolomide

Combining causal and correlative approaches to discover biomarkers of response to paclitaxel Research Perspective

Alberto Moscona-Nissan, Karl J. Habashy, Victor A. Arrieta, Adam M. Sonabend, Crismita Dmello

Published Jan 2, 2024 · Vol. 15, No. 1 · pp. 117-122

Keywords: glioblastoma, predictive biomarker, CRISPR screen, paclitaxel

Transformation-associated recombination (TAR) cloning and its applications for gene function; genome architecture and evolution; biotechnology and biomedicine Review

Natalay Kouprina, Vladimir Larionov

Published Dec 19, 2023 · Vol. 14, No. 1 · pp. 1009-1033

Keywords: transformation-associated recombination, TAR, microbes, biomedicine, biotechnology

One more step toward treatment of PARP inhibitor-resistant ovarian cancers Editorial

Upasana Ray, Prabhu Thirusangu, Viji Shridhar

Published Dec 16, 2023 · Vol. 14, No. 1 · pp. 1034-1035

Keywords: ovarian cancer, PARP inhibitors, PG545, DNA damage, cell death

Genetic alterations in thyroid cancer mediating both resistance to BRAF inhibition and anaplastic transformation Research Perspective

Mark Lee, Luc GT Morris

Published Dec 15, 2023 · Vol. 15, No. 1 · pp. 36-48

Keywords: thyroid cancer, drug resistance, anaplastic transformation, BRAF inhibitors, PIK3CA

Determination of genetic predisposition to early breast cancer in women of Kazakh ethnicity Research Paper

Gulnur Zhunussova, Nazgul Omarbayeva, Dilyara Kaidarova, Saltanat Abdikerim, Natalya Mit, Ilya Kisselev, Kanagat Yergali, Aigul Zhunussova, Tatyana Goncharova, Aliya Abdrakhmanova, Leyla Djansugurova

Published Sep 25, 2023 · Vol. 14, No. 1 · pp. 860-877

Keywords: early-onset breast cancer, triple negative breast cancer, next-generation sequencing, pathogenic variant, Kazakh population

Addendum: Are anaplastic lymphoma kinase (ALK) and O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation driver biomarkers of pulmonary neuroendocrine tumors (NETs) and carcinomas (NECs)? Addendum

Birgitta Hiddinga, Karen Zwaenepoel, Annelies Janssens, Jan Van Meerbeeck, Patrick Pauwels

Published Sep 7, 2023

Analytic validation of NeXT Dx™, a comprehensive genomic profiling assay Research Paper

Juan-Sebastian Saldivar, Jason Harris, Erin Ayash, Manqing Hong, Prateek Tandon, Saloni Sinha, Patricia Miranda Hebron, Erin E. Houghton, Kaleigh Thorne, Laurie J. Goodman, Conan Li, Twinkal R. Marfatia, Joshua Anderson, Massimo Morra, John Lyle, Gabor Bartha, Richard Chen

Published Aug 25, 2023 · Vol. 14, No. 1 · pp. 789-806

Keywords: comprehensive genomic profiling, whole exome sequencing, whole transcriptome sequencing, tumor-normal, precision medicine

Peripheral surrogates of tumor burden to guide chemotherapeutic and immunotherapeutic strategies for HPV-associated malignancies Review

Meghali Goswami, Jeffrey Schlom, Renee N. Donahue

Published Aug 3, 2023 · Vol. 14, No. 1 · pp. 758-774

Keywords: HPV-associated malignancies, immunotherapy, circulating tumor DNA, circulating tumor cells, HPV-specific antibodies

Addendum: LP-284, a small molecule acylfulvene, exerts potent antitumor activity in preclinical non-Hodgkin’s lymphoma models and in cells deficient in DNA damage repair Addendum

Jianli Zhou, Drew Sturtevant, Cassie Love, Aditya Kulkarni, Neha Biyani, Umesh Kathad, Elizabeth Thacker, Sandeep Dave, Kishor Bhatia

Published Jul 13, 2023 · Vol. 14, No. 1 · pp. 722-722

Diphenyl ditelluride anticancer activity and DNA topoisomerase I poisoning in human colon cancer HCT116 cells Research Paper

André Luiz Mendes Juchem, Cristiano Trindade, Juliana Bondan da Silva, Miriana da Silva Machado, Temenouga Nikolova Guecheva, Jaqueline Cesar Rocha, Jenifer Saffi, Iuri Marques de Oliveira, João Antonio Pêgas Henriques, Alexandre Escargueil

Published Jun 16, 2023 · Vol. 14, No. 1 · pp. 637-649

Keywords: colorectal cancer, HCT116, diphenyl ditelluride, organotellurium, topoisomerase I

The dark side of PLK1: Implications for cancer and genomic instability Editorial

Lilia Gheghiani, Zheng Fu

Published Jun 7, 2023 · Vol. 14, No. 1 · pp. 657-659

Keywords: polo-like kinase 1 (PLK1), oncogene, chromosomal instability, cell cycle checkpoints, tumorigenesis

LP-284, a small molecule acylfulvene, exerts potent antitumor activity in preclinical non-Hodgkin's lymphoma models and in cells deficient in DNA damage repair Research Paper

Jianli Zhou, Drew Sturtevant, Cassie Love, Aditya Kulkarni, Neha Biyani, Umesh Kathad, Elizabeth Thacker, Sandeep Dave, Kishor Bhatia

Published Jun 5, 2023 · Vol. 14, No. 1 · pp. 597-611

Keywords: non-Hodgkin's lymphoma, DNA damage, homologous recombination repair, transcription-coupled nucleotide excision repair, ATM

Association of mutation and expression of the brother of the regulator of imprinted sites (BORIS) gene with breast cancer progression Research Paper

Mohammad Salman Akhtar, Naseem Akhter, Arshi Talat, Raed A. Alharbi, Abdulmajeed A.A. Sindi, Faisal Klufah, Hanan E. Alyahyawi, Abdulmohsen Alruwetei, Abrar Ahmad, Mazin A. Zamzami, SVS Deo, Syed Akhtar Husain, Osama A. Badi, Mohammad Jahir Khan

Published May 16, 2023 · Vol. 14, No. 1 · pp. 528-541

Keywords: BORIS, breast cancer, mutation, transcription factor, PCR-SSCP

Targeting H3K27me3 loss in pediatric brain tumors - a perspective on epigenetically guided cancer therapy Editorial

Michael Goldstein

Published May 5, 2023 · Vol. 14, No. 1 · pp. 444-447

Keywords: epigenetics, brain tumor, EZH2, H3K27me3, radiation therapy

Genetic modifiers of p53: opportunities for breast cancer therapies Editorial Perspective

Prabin Dhangada Majhi, Aman Sharma, D. Joseph Jerry

Published Mar 11, 2023 · Vol. 14, No. 1 · pp. 236-241

Keywords: p53, Li-Fraumeni syndrome, genetic modifiers, breast cancer, DNA repair

Selective protection of normal cells from chemotherapy, while killing drug-resistant cancer cells Review

Mikhail V. Blagosklonny

Published Mar 3, 2023 · Vol. 14, No. 1 · pp. 193-206

Keywords: oncology, resistance, cyclotherapy, trilaciclib, rapamycin

AGO2 in T-prolymphocytic leukemia: its canonical and non-canonical deregulation and function Editorial

Till Braun, Hanna Klepzig, Marco Herling

Published Feb 28, 2023 · Vol. 14, No. 1 · pp. 395-397

Keywords: T-PLL, AGO2, microRNA

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Prevalence and spectrum of germline BRCA1 and BRCA2 in a cohort of ovarian cancer patients from the Salento peninsula (Southern Italy): a matter of preventive health Research Paper

Differential expression of Mad2 gene is consequential to the patterns of histone H3 post-translational modifications in its promoter region in human esophageal cancer samples Research Paper

ATR inhibition using gartisertib enhances cell death and synergises with temozolomide and radiation in patient-derived glioblastoma cell lines Research Paper

Combining causal and correlative approaches to discover biomarkers of response to paclitaxel Research Perspective

Transformation-associated recombination (TAR) cloning and its applications for gene function; genome architecture and evolution; biotechnology and biomedicine Review

One more step toward treatment of PARP inhibitor-resistant ovarian cancers Editorial

Genetic alterations in thyroid cancer mediating both resistance to BRAF inhibition and anaplastic transformation Research Perspective

Determination of genetic predisposition to early breast cancer in women of Kazakh ethnicity Research Paper

Addendum: Are anaplastic lymphoma kinase (ALK) and O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation driver biomarkers of pulmonary neuroendocrine tumors (NETs) and carcinomas (NECs)? Addendum

Analytic validation of NeXT Dx™, a comprehensive genomic profiling assay Research Paper

Peripheral surrogates of tumor burden to guide chemotherapeutic and immunotherapeutic strategies for HPV-associated malignancies Review

Addendum: LP-284, a small molecule acylfulvene, exerts potent antitumor activity in preclinical non-Hodgkin’s lymphoma models and in cells deficient in DNA damage repair Addendum

Diphenyl ditelluride anticancer activity and DNA topoisomerase I poisoning in human colon cancer HCT116 cells Research Paper

The dark side of PLK1: Implications for cancer and genomic instability Editorial

LP-284, a small molecule acylfulvene, exerts potent antitumor activity in preclinical non-Hodgkin's lymphoma models and in cells deficient in DNA damage repair Research Paper

Association of mutation and expression of the brother of the regulator of imprinted sites (BORIS) gene with breast cancer progression Research Paper

Targeting H3K27me3 loss in pediatric brain tumors - a perspective on epigenetically guided cancer therapy Editorial

Genetic modifiers of p53: opportunities for breast cancer therapies Editorial Perspective

Selective protection of normal cells from chemotherapy, while killing drug-resistant cancer cells Review

AGO2 in T-prolymphocytic leukemia: its canonical and non-canonical deregulation and function Editorial

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Prevalence and spectrum of germline BRCA1 and BRCA2 in a cohort of ovarian cancer patients from the Salento peninsula (Southern Italy): a matter of preventive health Research Paper

Differential expression of Mad2 gene is consequential to the patterns of histone H3 post-translational modifications in its promoter region in human esophageal cancer samples Research Paper

ATR inhibition using gartisertib enhances cell death and synergises with temozolomide and radiation in patient-derived glioblastoma cell lines Research Paper

Combining causal and correlative approaches to discover biomarkers of response to paclitaxel Research Perspective

Transformation-associated recombination (TAR) cloning and its applications for gene function; genome architecture and evolution; biotechnology and biomedicine Review

One more step toward treatment of PARP inhibitor-resistant ovarian cancers Editorial

Genetic alterations in thyroid cancer mediating both resistance to BRAF inhibition and anaplastic transformation Research Perspective

Determination of genetic predisposition to early breast cancer in women of Kazakh ethnicity Research Paper

Addendum: Are anaplastic lymphoma kinase (ALK) and O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation driver biomarkers of pulmonary neuroendocrine tumors (NETs) and carcinomas (NECs)? Addendum

Analytic validation of NeXT Dx™, a comprehensive genomic profiling assay Research Paper

Peripheral surrogates of tumor burden to guide chemotherapeutic and immunotherapeutic strategies for HPV-associated malignancies Review

Addendum: LP-284, a small molecule acylfulvene, exerts potent antitumor activity in preclinical non-Hodgkin’s lymphoma models and in cells deficient in DNA damage repair Addendum

Diphenyl ditelluride anticancer activity and DNA topoisomerase I poisoning in human colon cancer HCT116 cells Research Paper

The dark side of PLK1: Implications for cancer and genomic instability Editorial

LP-284, a small molecule acylfulvene, exerts potent antitumor activity in preclinical non-Hodgkin's lymphoma models and in cells deficient in DNA damage repair Research Paper

Association of mutation and expression of the brother of the regulator of imprinted sites (BORIS) gene with breast cancer progression Research Paper

Targeting H3K27me3 loss in pediatric brain tumors - a perspective on epigenetically guided cancer therapy Editorial

Genetic modifiers of p53: opportunities for breast cancer therapies Editorial Perspective

Selective protection of normal cells from chemotherapy, while killing drug-resistant cancer cells Review

AGO2 in T-prolymphocytic leukemia: its canonical and non-canonical deregulation and function Editorial