The Oncosearch | Oncotarget

Genomic landscape of metastatic breast cancer (MBC) patients with methylthioadenosine phosphorylase (MTAP) loss Research Paper

Maroun Bou Zerdan, Prashanth Ashok Kumar, Elio Haroun, Nimisha Srivastava, Jeffrey Ross, Abirami Sivapiragasam

Published Feb 25, 2023 · Vol. 14, No. 1 · pp. 178-187

Keywords: breast cancer, metastatic, MTAP loss

GBP3-STING interaction in glioblastoma coordinates autophagy, anti-oxidative, and DNA repair programs in response to temozolomide Editorial

Jun Ma, Ziyu Wang, Clark C. Chen, Ming Li

Published Feb 16, 2023 · Vol. 14, No. 1 · pp. 483-484

Keywords: GBP3, MGMT, glioblastoma, temozolomide resistance, STING

The “extreme phenotype approach” applied to male breast cancer allows the identification of rare variants of ATR as potential breast cancer susceptibility alleles Research Paper

Martin Chevarin, Diana Alcantara, Juliette Albuisson, Marie-Agnès Collonge-Rame, Céline Populaire, Zohair Selmani, Amandine Baurand, Caroline Sawka, Geoffrey Bertolone, Patrick Callier, Yannis Duffourd, Philippe Jonveaux, Yves-Jean Bignon, Isabelle Coupier, François Cornelis, Christophe Cordier, Monique Mozelle-Nivoix, Jean-Baptiste Rivière, Paul Kuentz, Christel Thauvin, Romain Boidot, François Ghiringhelli, Marc O'Driscoll, Laurence Faivre, Sophie Nambot

Published Feb 1, 2023 · Vol. 14, No. 1 · pp. 111-125

Keywords: male breast cancer, genetic predisposition to cancer, exome sequencing, ATR, extreme phenotype

The chromatographic constitution of andiroba oil and its healing effects, compared to the LLLT outcomes, in oral mucositis induced in golden Syrian hamsters: a new treatment option Research Paper

Jessica T. Gomes, Ana Márcia V. Wanzeler, Sergio M.A. Júnior, Rosa Helena F. Chaves Soares, Carolina P. de Oliveira, Emanuelle de M. Rodrigues, Bruno M. Soares, Diego D.F.A. Alcantara, Rommel M.R. Burbano, Fabrício M. Tuji

Published Dec 22, 2022 · Vol. 14, No. 1 · pp. 23-39

Keywords: phytotherapeutic drugs, medical oncology, stomatitis, wound healing, low-level light therapy

The chromatographic constitution of andiroba oil and his healing effects, compared to the LLLT outcomes, in oral mucositis induced in Golden syrian hamsters: a new treatment option Research Paper

Jessica T. Gomes, Ana Márcia V. Wanzeler, Sergio M.A. Júnior, Rosa Helena F. Chaves Soares, Carolina P. de Oliveira, Emanuelle de M. Rodrigues, Bruno M. Soares, Diego D.F.A. Alcantara, Rommel M.R. Burbano, Fabrício M. Tuji

Published Dec 22, 2022

Keywords: phytotherapeutic drugs, medical oncology, stomatitis, wound healing, low-level light therapy

Treasures from trash in cancer research Research Perspective

Fabiano Cordeiro Moreira, Dionison Pereira Sarquis, Jorge Estefano Santana de Souza, Daniel de Souza Avelar, Taíssa Maria Thomaz Araújo, André Salim Khayat, Sidney Emanuel Batista dos Santos, Paulo Pimentel de Assumpção

Published Nov 4, 2022 · Vol. 13, No. 1 · pp. 1246-1257

Keywords: cancer metagenomics, cancer sncRNA expression, RNA-Seq variant calling

Predictive molecular biomarkers for determining neoadjuvant chemosensitivity in muscle invasive bladder cancer Research Paper

Neal Murphy, Andrew J. Shih, Paras Shah, Oksana Yaskiv, Houman Khalili, Anthony Liew, Annette T. Lee, Xin-Hua Zhu

Published Oct 20, 2022 · Vol. 13, No. 1 · pp. 1188-1200

Keywords: muscle invasive bladder cancer, neoadjuvant chemotherapy, gene expression, molecular subtyping, canonical correlation analysis

HDAC inhibitors suppress protein poly(ADP-ribosyl)ation and DNA repair protein levels and phosphorylation status in hematologic cancer cells: implications for their use in combination with PARP inhibitors and chemotherapeutic drugs Research Paper

Benigno C. Valdez, Yago Nieto, Bin Yuan, David Murray, Borje S. Andersson

Published Sep 24, 2022 · Vol. 13, No. 1 · pp. 1122-1135

Keywords: poly(ADP-ribosyl)ation, HDAC inhibitors, PARP inhibitors, chemotherapy, hematologic malignancy

Complementary CRISPR genome-wide genetic screens in PARP10-knockout and overexpressing cells identify synthetic interactions for PARP10-mediated cellular survival Research Paper

Jude B. Khatib, Emily M. Schleicher, Lindsey M. Jackson, Ashna Dhoonmoon, George-Lucian Moldovan, Claudia M. Nicolae

Published Sep 23, 2022 · Vol. 13, No. 1 · pp. 1078-1091

Keywords: PARP10, ATM, CRISPR screens, genome stability, cancer cell proliferation

Targeting Krebs-cycle-deficient renal cell carcinoma with Poly ADP-ribose polymerase inhibitors and low-dose alkylating chemotherapy Research Paper

Daiki Ueno, Juan C. Vasquez, Amrita Sule, Jiayu Liang, Jinny van Doorn, Ranjini Sundaram, Sam Friedman, Randy Caliliw, Shinji Ohtake, Xun Bao, Jing Li, Huihui Ye, Karla Boyd, Rong Rong Huang, Jack Dodson, Paul Boutros, Ranjit S. Bindra, Brian Shuch

Published Sep 3, 2022 · Vol. 13, No. 1 · pp. 1054-1067

Keywords: FH, SDHB, renal cell carcinoma, PARP inhibitor, temozolomide

Chemoradiation-induced alteration of programmed death-ligand 1, CD8+ tumor-infiltrating lymphocytes and mucin expression in rectal cancer Research Paper

Marina Baretti, Qingfeng Zhu, Wei Fu, Jeffrey Meyer, Hao Wang, Robert A. Anders, Nilofer S. Azad

Published Jul 6, 2022 · Vol. 13, No. 1 · pp. 907-917

Keywords: programmed death ligand 1, tumor-infiltrating lymphocytes, immune checkpoints, colorectal cancer, neoadjuvant chemoradiotherapy

Early-onset pancreatic cancer: a review of molecular mechanisms, management, and survival Review

Mark B. Ulanja, Alastair E. Moody, Bryce D. Beutler, Daniel Antwi-Amoabeng, Ganiyu A. Rahman, Olatunji B. Alese

Published Jun 4, 2022 · Vol. 13, No. 1 · pp. 828-841

Keywords: pancreatic cancer, gastrointestinal malignancy, epidemiology, pancreatic adenocarcinoma

Are anaplastic lymphoma kinase (ALK) and O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation driver biomarkers of pulmonary neuroendocrine tumors (NETs) and carcinomas (NECs)? Research Paper

Birgitta Hiddinga, Karen Zwaenepoel, Annelies Janssens, Jan Van Meerbeeck, Patrick Pauwels

Published May 13, 2022 · Vol. 13, No. 1 · pp. 800-809

Keywords: MGMT promoter methylation, anaplastic lymphoma kinase, neuroendocrine tumor, neuroendocrine carcinoma, small cell lung cancer

Patient-derived tumor models are attractive tools to repurpose drugs for ovarian cancer treatment: pre-clinical updates Review

Magdalena Cybula, Magdalena Bieniasz

Published Mar 11, 2022 · Vol. 13, No. 1 · pp. 553-575

Keywords: PDX, ovarian cancer, repurposed drugs, tumor models

MYH9 binds to dNTPs via deoxyribose moiety and plays an important role in DNA synthesis Research Paper

Pratima Nangia-Makker, Malathy P.V. Shekhar, Victor Hogan, Vitaly Balan, Avraham Raz

Published Mar 9, 2022 · Vol. 13, No. 1 · pp. 534-550

Keywords: myosin II, MYH9, dNTP, deoxyribose-5-phosphate, DNA synthesis

Adjuvant osimertinib treatment in patients with early stage NSCLC (IB-IIIA): pathological pathway adaptations Review

Antonio Marchetti, Fiamma Buttitta, Emanuela D’Angelo

Published Feb 25, 2022 · Vol. 13, No. 1 · pp. 456-463

Keywords: non-small cell lung cancer, osimertinib, diagnostics, early, survival

Impact of combining vitamin C with radiation therapy in human breast cancer: does it matter? Research Paper

Somayeh Khazaei, Linn Nilsson, Gabriel Adrian, Helga Tryggvadottir, Elise Konradsson, Signe Borgquist, Karolin Isaksson, Crister Ceberg, Helena Jernström

Published Feb 17, 2022 · Vol. 13, No. 1 · pp. 439-453

Keywords: human breast cancer, radiation therapy, vitamin C, in vitro, clinical outcome

The role of IGF-pathway biomarkers in determining risks, screening, and prognosis in lung cancer Review

Alexander W. Pohlman, Hita Moudgalya, Lia Jordano, Gabriela C. Lobato, David Gerard, Michael J. Liptay, Christopher W. Seder, Jeffrey A. Borgia

Published Feb 15, 2022 · Vol. 13, No. 1 · pp. 393-407

Keywords: IGF, lung cancer, biomarkers, screening, prognostication

Telomere shortening accelerates tumor initiation in the L2-IL1B mouse model of Barrett esophagus and emerges as a possible biomarker Research Paper

Vincenz Sahm, Carlo Maurer, Theresa Baumeister, Akanksha Anand, Julia Strangmann, Roland M. Schmid, Timothy C. Wang, Michael Quante

Published Feb 10, 2022 · Vol. 13, No. 1 · pp. 347-359

Keywords: Barrett's esophagus, telomere shortening, esophageal cancer, risk factor, TERT/TERC

Etoposide-induced DNA damage is increased in p53 mutants: identification of ATR and other genes that influence effects of p53 mutations on Top2-induced cytotoxicity Research Paper

Daniel Menendez, Jay R. Anand, Carri C. Murphy, Whitney J. Bell, Jiaqi Fu, Nadia Slepushkina, Eugen Buehler, Scott E. Martin, Madhu Lal-Nag, John L. Nitiss, Michael A. Resnick

Published Feb 4, 2022 · Vol. 13, No. 1 · pp. 332-346

Keywords: tumor suppressor, siRNA screen, synthetic lethality, ICE assay, Top2 covalent complexes

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Genomic landscape of metastatic breast cancer (MBC) patients with methylthioadenosine phosphorylase (MTAP) loss Research Paper

GBP3-STING interaction in glioblastoma coordinates autophagy, anti-oxidative, and DNA repair programs in response to temozolomide Editorial

The “extreme phenotype approach” applied to male breast cancer allows the identification of rare variants of ATR as potential breast cancer susceptibility alleles Research Paper

The chromatographic constitution of andiroba oil and its healing effects, compared to the LLLT outcomes, in oral mucositis induced in golden Syrian hamsters: a new treatment option Research Paper

The chromatographic constitution of andiroba oil and his healing effects, compared to the LLLT outcomes, in oral mucositis induced in Golden syrian hamsters: a new treatment option Research Paper

Treasures from trash in cancer research Research Perspective

Predictive molecular biomarkers for determining neoadjuvant chemosensitivity in muscle invasive bladder cancer Research Paper

HDAC inhibitors suppress protein poly(ADP-ribosyl)ation and DNA repair protein levels and phosphorylation status in hematologic cancer cells: implications for their use in combination with PARP inhibitors and chemotherapeutic drugs Research Paper

Complementary CRISPR genome-wide genetic screens in PARP10-knockout and overexpressing cells identify synthetic interactions for PARP10-mediated cellular survival Research Paper

Targeting Krebs-cycle-deficient renal cell carcinoma with Poly ADP-ribose polymerase inhibitors and low-dose alkylating chemotherapy Research Paper

Chemoradiation-induced alteration of programmed death-ligand 1, CD8+ tumor-infiltrating lymphocytes and mucin expression in rectal cancer Research Paper

Early-onset pancreatic cancer: a review of molecular mechanisms, management, and survival Review

Are anaplastic lymphoma kinase (ALK) and O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation driver biomarkers of pulmonary neuroendocrine tumors (NETs) and carcinomas (NECs)? Research Paper

Patient-derived tumor models are attractive tools to repurpose drugs for ovarian cancer treatment: pre-clinical updates Review

MYH9 binds to dNTPs via deoxyribose moiety and plays an important role in DNA synthesis Research Paper

Adjuvant osimertinib treatment in patients with early stage NSCLC (IB-IIIA): pathological pathway adaptations Review

Impact of combining vitamin C with radiation therapy in human breast cancer: does it matter? Research Paper

The role of IGF-pathway biomarkers in determining risks, screening, and prognosis in lung cancer Review

Telomere shortening accelerates tumor initiation in the L2-IL1B mouse model of Barrett esophagus and emerges as a possible biomarker Research Paper

Etoposide-induced DNA damage is increased in p53 mutants: identification of ATR and other genes that influence effects of p53 mutations on Top2-induced cytotoxicity Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Genomic landscape of metastatic breast cancer (MBC) patients with methylthioadenosine phosphorylase (MTAP) loss Research Paper

GBP3-STING interaction in glioblastoma coordinates autophagy, anti-oxidative, and DNA repair programs in response to temozolomide Editorial

The “extreme phenotype approach” applied to male breast cancer allows the identification of rare variants of ATR as potential breast cancer susceptibility alleles Research Paper

The chromatographic constitution of andiroba oil and its healing effects, compared to the LLLT outcomes, in oral mucositis induced in golden Syrian hamsters: a new treatment option Research Paper

The chromatographic constitution of andiroba oil and his healing effects, compared to the LLLT outcomes, in oral mucositis induced in Golden syrian hamsters: a new treatment option Research Paper

Treasures from trash in cancer research Research Perspective

Predictive molecular biomarkers for determining neoadjuvant chemosensitivity in muscle invasive bladder cancer Research Paper

HDAC inhibitors suppress protein poly(ADP-ribosyl)ation and DNA repair protein levels and phosphorylation status in hematologic cancer cells: implications for their use in combination with PARP inhibitors and chemotherapeutic drugs Research Paper

Complementary CRISPR genome-wide genetic screens in PARP10-knockout and overexpressing cells identify synthetic interactions for PARP10-mediated cellular survival Research Paper

Targeting Krebs-cycle-deficient renal cell carcinoma with Poly ADP-ribose polymerase inhibitors and low-dose alkylating chemotherapy Research Paper

Chemoradiation-induced alteration of programmed death-ligand 1, CD8+ tumor-infiltrating lymphocytes and mucin expression in rectal cancer Research Paper

Early-onset pancreatic cancer: a review of molecular mechanisms, management, and survival Review

Are anaplastic lymphoma kinase (ALK) and O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation driver biomarkers of pulmonary neuroendocrine tumors (NETs) and carcinomas (NECs)? Research Paper

Patient-derived tumor models are attractive tools to repurpose drugs for ovarian cancer treatment: pre-clinical updates Review

MYH9 binds to dNTPs via deoxyribose moiety and plays an important role in DNA synthesis Research Paper

Adjuvant osimertinib treatment in patients with early stage NSCLC (IB-IIIA): pathological pathway adaptations Review

Impact of combining vitamin C with radiation therapy in human breast cancer: does it matter? Research Paper

The role of IGF-pathway biomarkers in determining risks, screening, and prognosis in lung cancer Review

Telomere shortening accelerates tumor initiation in the L2-IL1B mouse model of Barrett esophagus and emerges as a possible biomarker Research Paper

Etoposide-induced DNA damage is increased in p53 mutants: identification of ATR and other genes that influence effects of p53 mutations on Top2-induced cytotoxicity Research Paper