|
| Tcell therapy against cancer mutations |
|
https://doi.org/10.18632/oncotarget.2234
Eric Tran, and Steven A. Rosenberg
|
| 4579-4580 |
|
| Oncogenic nexus of cancerous inhibitor of protein phosphatase 2A CIP2A: an oncoprotein with many hands |
|
https://doi.org/10.18632/oncotarget.2127
Pradip De, Jennifer Carlson, Brian Leyland-Jones, and Nandini Dey
|
| 4581-4602 |
|
| Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention |
|
https://doi.org/10.18632/oncotarget.2209
Nicole M. Davis, Melissa Sokolosky, Kristin Stadelman, Stephen L. Abrams, Massimo Libra, Saverio Candido, Ferdinando Nicoletti, Jerry Polesel, Roberta Maestro, Antonino D’Assoro, Lyudmyla Drobot, Dariusz Rakus, Agnieszka Gizak, Piotr Laidler, Joanna Dulińska-Litewka, Joerg Basecke, Sanja Mijatovic, Danijela Maksimovic-Ivanic, Giuseppe Montalto, Melchiorre Cervello, Timothy L. Fitzgerald, Zoya N. Demidenko, Alberto M. Martelli, Lucio Cocco, Linda S. Steelman, and James A. McCubrey
|
| 4603-4650 |
|
| Characterization of tumorassociated Bcell subsets in patients with colorectal cancer |
|
https://doi.org/10.18632/oncotarget.1701
Alexander Shimabukuro-Vornhagen, Hans A. Schlößer, Luise Gryschok, Joke Malcher, Kerstin Wennhold, Maria Garcia-Marquez, Till Herbold, Laura S. Neuhaus, Hans J. Becker, Anne Fiedler, Pascal Scherwitz, Thomas Koslowsky, Roland Hake, Dirk L. Stippel, Arnulf H. Hoelscher, Sebastian Eidt, Michael Hallek, Sebastian Theurich, and Michael S. von Bergwelt-Baildon
|
| 4651-4664 |
|
| Identification of kitM541L somatic mutation in chronic eosinophilic leukemia not otherwise specified and its implication in lowdose imatinib response |
|
https://doi.org/10.18632/oncotarget.1941
Alessandra Iurlo, Umberto Gianelli, Alessandro Beghini, Orietta Spinelli, Nicola Orofino, Francesca Lazzaroni, Stefano Cambiaghi, Tamara Intermesoli, Alessandro Rambaldi, and Agostino Cortelezzi
|
| 4665-4670 |
|
| Investigation of IL23 p19 p40 and IL23R identifies nuclear expression of IL23 p19 as a favorable prognostic factor in colorectal cancer: a retrospective multicenter study of 675 patients |
|
https://doi.org/10.18632/oncotarget.2069
Melina Helbling, Anne Lukesch, Aladin Haimovici, Eva Karamitopoulou, Martin D. Berger, Marion Hädrich, Makhmud Mallaev, Beat Schnüriger, Viktor H. Koelzer, Heather Dawson, Markus Borner, Rupert Langer, Robert Rosenberg, Ulrich Nitsche, Daniel Inderbitzin, Alessandro Lugli, Mario P. Tschan, and Inti Zlobec
|
| 4671-4682 |
|
| A radiosensitivity gene signature in predicting glioma prognostic via EMT pathway |
|
https://doi.org/10.18632/oncotarget.2088
Jin Meng, Ping Li, Qing Zhang, Zhangru Yang, and Shen Fu
|
| 4683-4693 |
|
| High p27 protein levels in chronic lymphocytic leukemia are associated to low Myc and Skp2 expression confer resistance to apoptosis and antagonize Myc effects on cell cycle |
|
https://doi.org/10.18632/oncotarget.2100
Juan M. Caraballo, Juan C. Acosta, Miguel A. Cortés, Marta Albajar, Teresa M. Gómez-Casares, Ana Batlle-López, Angeles M. Cuadrado, Arantza Onaindia, Gabriel Bretones, Javier Llorca, Miguel A. Piris, Dolors Colomer, and Javier León
|
| 4694-4708 |
|
| Intrinsic bevacizumab resistance is associated with prolonged activation of autocrine VEGF signaling and hypoxia tolerance in colorectal cancer cells and can be overcome by nintedanib a small molecule angiokinase inhibitor |
|
https://doi.org/10.18632/oncotarget.1671
Paul Mésange, Virginie Poindessous, Michèle Sabbah, Alexandre E. Escargueil, Aimery de Gramont, and Annette K. Larsen
|
| 4709-4721 |
|
| Capturing the metabolomic diversity of KRAS mutants in nonsmallcell lung cancer cells |
|
https://doi.org/10.18632/oncotarget.1958
Laura Brunelli, Elisa Caiola, Mirko Marabese, Massimo Broggini, and Roberta Pastorelli
|
| 4722-4731 |
|
| Adiponectin promotes pancreatic cancer progression by inhibiting apoptosis via the activation of AMPK/Sirt1/PGC1α signaling |
|
https://doi.org/10.18632/oncotarget.1963
Bingqing Huang, Xixi Cheng, Dan Wang, Meiyu Peng, Zhenyi Xue, Yurong Da, Ning Zhang, Zhi Yao, Min Li, Aimin Xu, and Rongxin Zhang
|
| 4732-4745 |
|
| Metformin limits the adipocyte tumorpromoting effect on ovarian cancer |
|
https://doi.org/10.18632/oncotarget.2012
Calvin Tebbe, Jasdeep Chhina, Sajad A. Dar, Kalli Sarigiannis, Shailendra Giri, Adnan R. Munkarah, and Ramandeep Rattan
|
| 4746-4764 |
|
| Combining AKT inhibition with chloroquine and gefitinib prevents compensatory autophagy and induces cell death in EGFR mutated NSCLC cells |
|
https://doi.org/10.18632/oncotarget.2017
Sivan M. Bokobza, Yanyan Jiang, Anika M. Weber, Aoife M. Devery, and Anderson J. Ryan
|
| 4765-4778 |
|
| A polymorphism in JMJD2C alters the cleavage by caspase3 and the prognosis of human breast cancer |
|
https://doi.org/10.18632/oncotarget.2029
Qi Hong, Sanjian Yu, Yu Yang, Guangyu Liu, and Zhiming Shao
|
| 4779-4787 |
|
| Nicotine and oxidative stress induced exomic variations are concordant and overrepresented in cancerassociated genes |
|
https://doi.org/10.18632/oncotarget.2033
Jasmin H. Bavarva, Hongseok Tae, Lauren McIver, and Harold R. Garner
|
| 4788-4798 |
|
| Enhanced Orai1 and STIM1 expression as well as store operated Ca2+ entry in therapy resistant ovary carcinoma cells |
|
https://doi.org/10.18632/oncotarget.2035
Sebastian Schmidt, Guoxing Liu, Guilai Liu, Wenting Yang, Sabina Honisch, Stavros Pantelakos, Christos Stournaras, Arnd Hönig, and Florian Lang
|
| 4799-4810 |
|
| Antitumor activity of fenretinide complexed with human serum albumin in lung cancer xenograft mouse model |
|
https://doi.org/10.18632/oncotarget.2038
Sandra Durante, Isabella Orienti, Gabriella Teti, Viviana Salvatore, Stefano Focaroli, Anna Tesei, Sara Pignatta, and Mirella Falconi
|
| 4811-4820 |
|
| MicroRNA31 suppresses medulloblastoma cell growth by inhibiting DNA replication through minichromosome maintenance 2 |
|
https://doi.org/10.18632/oncotarget.2043
Yucui Jin, Anwen Xiong, Ziyu Zhang, Sanen Li, Huijie Huang, Ting-ting Yu, Xiumei Cao, and Steven Y. Cheng
|
| 4821-4833 |
|
| Tumor suppressor FOXO3 regulates ribonucleotide reductase subunit RRM2B and impacts on survival of cancer patients |
|
https://doi.org/10.18632/oncotarget.2044
Er-Chieh Cho, Mei-Ling Kuo, Xiyong Liu, Lixin Yang, Yi-Chen Hsieh, Jinghan Wang, Yawen Cheng, and Yun Yen
|
| 4834-4844 |
|
| Lapatinib induces autophagic cell death and inhibits growth of human hepatocellular carcinoma |
|
https://doi.org/10.18632/oncotarget.2045
Yu-Jen Chen, Chih-Wen Chi, Wen-Chi Su, and Huey-Lan Huang
|
| 4845-4854 |
|
| HGF/cMet axis drives cancer aggressiveness in the neoadjuvant setting of ovarian cancer |
|
https://doi.org/10.18632/oncotarget.2049
Marisa Mariani, Mark McHugh, Marco Petrillo, Steven Sieber, Shiquan He, Mirko Andreoli, Zheyang Wu, Paul Fiedler, Giovanni Scambia, Shohreh Shahabi, and Cristiano Ferlini
|
| 4855-4867 |
|
| Afatinib and its encapsulated polymeric micelles inhibits HER2overexpressed colorectal tumor cell growth in vitro and in vivo |
|
https://doi.org/10.18632/oncotarget.2050
Siao-Syun Guan, Jungshan Chang, Chun-Chia Cheng, Tsai-Yueh Luo, Ai-Sheng Ho, Chia-Chi Wang, Cheng-Tien Wu, and Shing-Hwa Liu
|
| 4868-4880 |
|
| Selective inhibition of unfolded protein response induces apoptosis in pancreatic cancer cells |
|
https://doi.org/10.18632/oncotarget.2051
Wenwen Chien, Ling-Wen Ding, Qiao-Yang Sun, Lucia A. Torres-Fernandez, Siew Zhuan Tan, Jinfen Xiao, Su Lin Lim, Manoj Garg, Kian Leong Lee, Shojiro Kitajima, Sumiko Takao, Wei Zhong Leong, Haibo Sun, Itay Tokatly, Lorenz Poellinger, Sigal Gery, and Phillip H. Koeffler
|
| 4881-4894 |
|
| Tumorderived CXCL8 signaling augments stromaderived CCL2promoted proliferation and CXCL12mediated invasion of PTENdeficient prostate cancer cells |
|
https://doi.org/10.18632/oncotarget.2052
Pamela J. Maxwell, Jessica Neisen, Johanna Messenger, and David J.J. Waugh
|
| 4895-4908 |
|
| RFX1–dependent activation of SHP1 induces autophagy by a novel obatoclax derivative in hepatocellular carcinoma cells |
|
https://doi.org/10.18632/oncotarget.2054
Jung-Chen Su, Ping-Hui Tseng, Cheng-Yi Hsu, Wei-Tien Tai, Jui-Wen Huang, Ching-Huai Ko, Mai-Wei Lin, Chun-Yu Liu, Kuen-Feng Chen, and Chung-Wai Shiau
|
| 4909-4919 |
|
| Receptor ligandtriggered resistance to alectinib and its circumvention by Hsp90 inhibition in EML4ALK lung cancer cells |
|
https://doi.org/10.18632/oncotarget.2055
Azusa Tanimoto, Tadaaki Yamada, Shigeki Nanjo, Shinji Takeuchi, Hiromichi Ebi, Kenji Kita, Kunio Matsumoto, and Seiji Yano
|
| 4920-4928 |
|
| Thioridazine inhibits angiogenesis and tumor growth by targeting the VEGFR2/PI3K/mTOR pathway in ovarian cancer xenografts |
|
https://doi.org/10.18632/oncotarget.2063
Mi Sun Park, Seung Myung Dong, Boh-Ram Kim, Seung Hee Seo, Sokbom Kang, Eun-Ju Lee, Seung-Hoon Lee, and Seung Bae Rho
|
| 4929-4934 |
|
| The antihypertension drug doxazosin inhibits tumor growth and angiogenesis by decreasing VEGFR2/Akt/mTOR signaling and VEGF and HIF1α expression |
|
https://doi.org/10.18632/oncotarget.2064
Mi Sun Park, Boh-Ram Kim, Seung Myung Dong, Seung-Hoon Lee, Dae-Yong Kim, and Seung Bae Rho
|
| 4935-4944 |
|
| Engineered ubiquitin ligase PTBUbox targets insulin/insulinlike growth factor receptor for degradation and coordinately inhibits cancer malignancy |
|
https://doi.org/10.18632/oncotarget.2066
Qinhao Wang, Yi Ru, Daixing Zhong, Jing Zhang, Libo Yao, and Xia Li
|
| 4945-4958 |
|
| miR942 decreases TRAILinduced apoptosis through ISG12a downregulation and is regulated by AKT |
|
https://doi.org/10.18632/oncotarget.2067
Nianli Liu, Chaohui Zuo, Xiaohong Wang, Tianran Chen, Darong Yang, Jing Wang, and Haizhen Zhu
|
| 4959-4971 |
|
| Silibinin strongly inhibits the growth kinetics of colon cancer stem cellenriched spheroids by modulating interleukin 4/6mediated survival signals |
|
https://doi.org/10.18632/oncotarget.2068
Sushil Kumar, Komal Raina, Chapla Agarwal, and Rajesh Agarwal
|
| 4972-4989 |
|
| Synergistic induction of apoptosis by combination of BTK and dual mTORC1/2 inhibitors in diffuse large B cell lymphoma |
|
https://doi.org/10.18632/oncotarget.2071
Scott A. Ezell, Michele Mayo, Teeru Bihani, Suprawee Tepsuporn, Suping Wang, Melissa Passino, Shaun E. Grosskurth, Mike Collins, Julie Parmentier, Corinne Reimer, and Kate F. Byth
|
| 4990-5001 |
|
| Yin Yang 1 is a target of microRNA34 family and contributes to gastric carcinogenesis |
|
https://doi.org/10.18632/oncotarget.2073
An-Ming Wang, Tzu-Ting Huang, Kai-Wen Hsu, Kuo-Hung Huang, Wen-Liang Fang, Muh-Hwa Yang, Su-Shun Lo, Chin-Wen Chi, Jing-Jer Lin, and Tien-Shun Yeh
|
| 5002-5016 |
|
| GCIP functions as a tumor suppressor in nonsmall cell lung cancer by suppressing Id1mediated tumor promotion |
|
https://doi.org/10.18632/oncotarget.2075
Kuan-yu Chen, Chao-chung Chen, Yau-lin Tseng, Yi-chien Chang, and Ming-Chung Chang
|
| 5017-5028 |
|
| Sulfatase 1 hSulf1 reverses basic fibroblast growth factorstimulated signaling and inhibits growth of hepatocellular carcinoma in animal model |
|
https://doi.org/10.18632/oncotarget.2078
Gaoya Xu, Weidan Ji, Yinghan Su, Yang Xu, Yan Yan, Shuwen Shen, Xiaoya Li, Bin Sun, Haihua Qian, Lei Chen, Xiaohui Fu, Mengchao Wu, and Changqing Su
|
| 5029-5039 |
|
| The MAPK pathway as an apoptosis enhancer in melanoma |
|
https://doi.org/10.18632/oncotarget.2079
Johannes M. Haydn, Anita Hufnagel, Johannes Grimm, Katja Maurus, Manfred Schartl, and Svenja Meierjohann
|
| 5040-5053 |
|
| Insights from yeast into whether the rapamycin inhibition of heat shock transcription factor Hsf1 can prevent the Hsf1 activation that results from treatment with an Hsp90 inhibitor |
|
https://doi.org/10.18632/oncotarget.2077
Stefan H. Millson, and Peter W. Piper
|
| 5054-5064 |
|
| Mutational analysis of primary central nervous system lymphoma |
|
https://doi.org/10.18632/oncotarget.2080
Aurélie Bruno, Blandine Boisselier, Karim Labreche, Yannick Marie, Marc Polivka, Anne Jouvet, Clovis Adam, Dominique Figarella-Branger, Catherine Miquel, Sandrine Eimer, Caroline Houillier, Carole Soussain, Karima Mokhtari, Romain Daveau, and Khê Hoang-Xuan
|
| 5065-5075 |
|
| Niraparib MK4827 a novel polyADPRibose polymerase inhibitor radiosensitizes human lung and breast cancer cells |
|
https://doi.org/10.18632/oncotarget.2083
Kathleen A. Bridges, Carlo Toniatti, Carolyn A. Buser, Huifeng Liu, Thomas A. Buchholz, and Raymond E. Meyn
|
| 5076-5086 |
|
| Visfatin promotes cell and tumor growth by upregulating Notch1 in breast cancer |
|
https://doi.org/10.18632/oncotarget.2086
Hyun-Joo Park, Su-Ryun Kim, Su Seong Kim, Hee-Jun Wee, Moon-Kyoung Bae, Mi Heon Ryu, and Soo-Kyung Bae
|
| 5087-5099 |
|
| Targeting the KRas JNK axis eliminates cancer stemlike cells and prevents pancreatic tumor formation |
|
https://doi.org/10.18632/oncotarget.2087
Masashi Okada, Keita Shibuya, Atsushi Sato, Shizuka Seino, Shuhei Suzuki, Manabu Seino, and Chifumi Kitanaka
|
| 5100-5112 |
|
| FoxD3regulated microRNA137 suppresses tumour growth and metastasis in human hepatocellular carcinoma by targeting AKT2 |
|
https://doi.org/10.18632/oncotarget.2089
Li-Li Liu, Shi-Xun Lu, Min Li, Lin-Zi Li, Jia Fu, Wen Hu, Yuan-Zhong Yang, Rong-Zhen Luo, Chris Zhiyi Zhang, and Jing-Ping Yun
|
| 5113-5124 |
|
| HRas regulation of TRAIL death receptor mediated apoptosis |
|
https://doi.org/10.18632/oncotarget.2091
Jun-Jie Chen, William P. Bozza, Xu Di, Yaqin Zhang, William Hallett, and Baolin Zhang
|
| 5125-5137 |
|
| ERBB3 knockdown induces cell cycle arrest and activation of Bak and Baxdependent apoptosis in colon cancer cells |
|
https://doi.org/10.18632/oncotarget.2094
Hyunji Lee, Hyunjung Lee, Hyunjung Chin, Kyoungmi Kim, and Daekee Lee
|
| 5138-5152 |
|
| The subcellular distribution and function of MTA1 in cancer differentiation |
|
https://doi.org/10.18632/oncotarget.2095
Jian Liu, Dongkui Xu, Haijuan Wang, Ying Zhang, Yanan Chang, Jinlong Zhang, Jia Wang, Chunxiao Li, Huan Liu, Mei Zhao, Chen Lin, Qimin Zhan, Changzhi Huang, and Haili Qian
|
| 5153-5164 |
|
| RPL24: a potential therapeutic target whose depletion or acetylation inhibits polysome assembly and cancer cell growth |
|
https://doi.org/10.18632/oncotarget.2099
Kathleen A. Wilson-Edell, Amanuel Kehasse, Gary K. Scott, Christina Yau, Daniel E. Rothschild, Birgit Schilling, Bianca S. Gabriel, Mariya A. Yevtushenko, Ingrid M. Hanson, Jason M. Held, Bradford W. Gibson, and Christopher C. Benz
|
| 5165-5176 |
|
| Inhibition of glucose turnover by 3bromopyruvate counteracts pancreatic cancer stem cell features and sensitizes cells to gemcitabine |
|
https://doi.org/10.18632/oncotarget.2120
Orkhan Isayev, Vanessa Rausch, Nathalie Bauer, Li Liu, Pei Fan, Yiyao Zhang, Jury Gladkich, Clifford C. Nwaeburu, Jürgen Mattern, Martin Mollenhauer, Felix Rückert, Sebastian Zach, Uwe Haberkorn, Wolfgang Gross, Frank Schönsiegel, Alexandr V. Bazhin, and Ingrid Herr
|
| 5177-5189 |