The Oncosearch | Oncotarget

Investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish Research Paper

Hyejeong Rosemary Kim, Kirankumar Santhakumar, Eleanor Markham, Davide Baldera, David Greenald, Helen E. Bryant, Sherif F. El-Khamisy, Fredericus J. van Eeden

Published Mar 31, 2020 · Vol. 11, No. 13 · pp. 1109-1130

Keywords: Hif, Vhl, DNA repair, apoptosis, chemo/radio-resistance

Exosome mediated miR-155 delivery confers cisplatin chemoresistance in oral cancer cells via epithelial-mesenchymal transition Research Paper

Prathibha Kirave, Piyush Gondaliya, Bhagyashri Kulkarni, Rakesh Rawal, Rachana Garg, Alok Jain, Kiran Kalia

Published Mar 31, 2020 · Vol. 11, No. 13 · pp. 1157-1171

Keywords: cisplatin chemoresistance, miRNA155, exosomes, oral cancer, apoptosis

Origin and role of hepatic myofibroblasts in hepatocellular carcinoma Review

Betul Gok Yavuz, Roberto Carmagnani Pestana, Yehia I. Abugabal, Sunil Krishnan, Jian Chen, Manal M. Hassan, Robert A. Wolff, Asif Rashid, Hesham M. Amin, Ahmed O. Kaseb

Published Mar 31, 2020 · Vol. 11, No. 13 · pp. 1186-1201

Keywords: hepatocellular carcinoma, stellate cells, myofibroblasts, liver fibrosis, immunotherapy

Correction: Overexpression of AKR1C3 significantly enhances human prostate cancer cells resistance to radiation Correction

Shao-Qian Sun, Xiaobin Gu, Xian-Shu Gao, Yi Li, Hongliang Yu, Wei Xiong, Hao Yu, Wen Wang, Yingbo Li, Yingqi Teng, Demin Zhou

Published Mar 24, 2020 · Vol. 11, No. 17 · pp. 1575-1575

Cancer associated fibroblasts confer shear resistance to circulating tumor cells during prostate cancer metastatic progression Research Paper

Nerymar Ortiz-Otero, Andrea B. Clinch, Jacob Hope, Wenjun Wang, Cynthia A. Reinhart-King, Michael R. King

Published Mar 24, 2020 · Vol. 11, No. 12 · pp. 1037-1050

Keywords: metastasis, cancer associated fibroblasts, circulating tumor cells, cytoprotection, collective migration

The prognostic role of microRNA in epithelial ovarian cancer: a systematic review of literature with an overall survival meta-analysis Review

Patricia Ferreira, Rosimeire Aparecida Roela, Rossana Veronica Mendoza Lopez, Maria Del Pilar Estevez-Diz

Published Mar 24, 2020 · Vol. 11, No. 12 · pp. 1085-1095

Keywords: ovarian cancer, microRNA, miRNA, prognostic factors, overall survival

Early prediction of resistance to tyrosine kinase inhibitors by plasma monitoring of EGFR mutations in NSCLC: a new algorithm for patient selection and personalized treatment Research Paper

Fiamma Buttitta, Lara Felicioni, Alessia Di Lorito, Alessio Cortellini, Luciana Irtelli, Davide Brocco, Pietro Di Marino, Donatella Traisci, Nicola D’Ostilio, Alessandra Di Paolo, Francesco Malorgio, Pasquale Assalone, Sonia Di Felice, Francesca Fabbri, Giovanni Cianci, Michele De Tursi, Antonio Marchetti

Published Mar 17, 2020 · Vol. 11, No. 11 · pp. 982-991

Keywords: epidermal growth factor receptor (EGFR), tyrosine-kinase Inhibitors, circulating tumor-DNA (ct-DNA), massive parallel sequencing (MPS), resistance-inducing mutation

Quizartinib, a selective FLT3 inhibitor, maintains antileukemic activity in preclinical models of RAS-mediated midostaurin-resistant acute myeloid leukemia cells Research Paper

Tomoya Aikawa, Noriko Togashi, Koichi Iwanaga, Hiroyuki Okada, Yumi Nishiya, Shinichi Inoue, Mark J. Levis, Takeshi Isoyama

Published Mar 17, 2020 · Vol. 11, No. 11 · pp. 943-955

Keywords: relapsed/refractory AML, FLT3 inhibitors, quizartinib, AC886, midostaurin resistance

Acute promyelocytic leukemia (APL): a review of the literature Review

Joaquin J. Jimenez, Ravinder S. Chale, Andrea C. Abad, Andrew V. Schally

Published Mar 17, 2020 · Vol. 11, No. 11 · pp. 992-1003

Keywords: promyelocytic leukemia, arsenic trioxide, retinoic acid, resistance

Glypican-1 in human glioblastoma: implications in tumorigenesis and chemotherapy Research Paper

Eduardo Listik, Leny Toma

Published Mar 3, 2020 · Vol. 11, No. 9 · pp. 828-845

Keywords: glioblastoma, glypican-1, tumorigenesis, chemotherapy resistance, temozolomide

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

Cristina Kinahan, Michael A. Mangone, Luigi Scotto, Michele Visentin, Enrica Marchi, Hearn Jay Cho, Owen A. O’Connor

Published Feb 26, 2020 · Vol. 11, No. 18 · pp. 1576-1589

Keywords: antifolate, multiple myeloma, pralatrexate, biomarker, reduced folate carrier (RFC)

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

Cristina Kinahan, Michael A. Mangone, Luigi Scotto, Michele Visentin, Enrica Marchi, Hearn Jay Cho, Owen A. O’Connor

Published Feb 26, 2020

Keywords: antifolate, multiple myeloma, pralatrexate, biomarker, reduced folate carrier (RFC)

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

Cristina Kinahan, Michael A. Mangone, Luigi Scotto, Michele Visentin, Enrica Marchi, Hearn Jay Cho, Owen A. O’Connor

Published Feb 26, 2020

Keywords: antifolate, multiple myeloma, pralatrexate, biomarker, reduced folate carrier (RFC)

Subcellular localization of FANCD2 is associated with survival in ovarian carcinoma Research Paper

Sonali Joshi, Shawn Campbell, Jeong Y. Lim, Shannon McWeeney, Adam Krieg, Yukie Bean, Nadja Pejovic, Paulette Mhawech-Fauceglia, Tanja Pejovic

Published Feb 25, 2020 · Vol. 11, No. 8 · pp. 775-783

Keywords: FANCD2, ovarian carcinoma, subcellular localization

Both BRCA1-wild type and -mutant triple-negative breast cancers show sensitivity to the NAE inhibitor MLN4924 which is enhanced upon MLN4924 and cisplatin combination treatment Research Paper

Shrilekha Misra, Xiaoli Zhang, Nissar Ahmad Wani, Steven Sizemore, Alo Ray

Published Feb 25, 2020 · Vol. 11, No. 8 · pp. 784-800

Keywords: triple-negative breast cancer, MLN4924, cisplatin, cell cycle, DNA damage

Sphingomyelin phosphodiesterase 3 methylation and silencing in oral squamous cell carcinoma results in increased migration and invasion and altered stress response Research Paper

James Jabalee, Rebecca Towle, James Lawson, Christopher Dickman, Cathie Garnis

Published Feb 4, 2020 · Vol. 11, No. 5 · pp. 523-534

Keywords: oral squamous cell carcinoma, DNA methylation, SMPD3, erlotinib, cancer progression

Correction: Metabolomic analysis of uterine serous carcinoma with acquired resistance to paclitaxel Correction

Manabu Seino, Tsuyoshi Ohta, Akiko Sugiyama, Hirotsugu Sakaki, Takeshi Sudo, Seiji Tsutsumi, Shogo Shigeta, Hideki Tokunaga, Masafumi Toyoshima, Nobuo Yaegashi, Satoru Nagase

Published Jan 28, 2020 · Vol. 12, No. 23 · pp. 2321-2322

Resistance to allosteric SHP2 inhibition in FGFR-driven cancers through rapid feedback activation of FGFR Research Paper

Hengyu Lu, Chen Liu, Hung Huynh, Thi Bich Uyen Le, Matthew J. LaMarche, Morvarid Mohseni, Jeffrey A. Engelman, Peter S. Hammerman, Giordano Caponigro, Huai-Xiang Hao

Published Jan 21, 2020 · Vol. 11, No. 3 · pp. 265-281

Keywords: SHP2, FGFR, resistance, feedback activation

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

Wayne D. Blosser, Jack A. Dempsey, Ann M. McNulty, Xi Rao, Philip J. Ebert, Caitlin D. Lowery, Philip W. Iversen, Yue Wang Webster, Gregory P. Donoho, Xueqian Gong, Farhana F. Merzoug, Sean Buchanan, Karsten Boehnke, Chunping Yu, Xin Tian You, Richard P. Beckmann, Wenjuan Wu, Samuel C. McNeely, Aimee Bence Lin, Ricardo Martinez

Published Jan 21, 2020 · Vol. 11, No. 3 · pp. 216-236

Keywords: CHK1, prexasertib, replication stress, replication fork, innate immunity

Response of a chemo-resistant triple-negative breast cancer patient to a combination of p62-encoding plasmid, Elenagen, and CMF chemotherapy Case Report

Dmitry M. Ponomarenko, Vladimir L. Gabai, Albert A. Sufianov, Sergey I. Kolesnikov, Alexander M. Shneider

Published Jan 21, 2020 · Vol. 11, No. 3 · pp. 294-299

Keywords: cancer immunotherapy, cancer chemotherapy, p62 plasmid, cancer vaccine

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Investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish Research Paper

Exosome mediated miR-155 delivery confers cisplatin chemoresistance in oral cancer cells via epithelial-mesenchymal transition Research Paper

Origin and role of hepatic myofibroblasts in hepatocellular carcinoma Review

Correction: Overexpression of AKR1C3 significantly enhances human prostate cancer cells resistance to radiation Correction

Cancer associated fibroblasts confer shear resistance to circulating tumor cells during prostate cancer metastatic progression Research Paper

The prognostic role of microRNA in epithelial ovarian cancer: a systematic review of literature with an overall survival meta-analysis Review

Early prediction of resistance to tyrosine kinase inhibitors by plasma monitoring of EGFR mutations in NSCLC: a new algorithm for patient selection and personalized treatment Research Paper

Quizartinib, a selective FLT3 inhibitor, maintains antileukemic activity in preclinical models of RAS-mediated midostaurin-resistant acute myeloid leukemia cells Research Paper

Acute promyelocytic leukemia (APL): a review of the literature Review

Glypican-1 in human glioblastoma: implications in tumorigenesis and chemotherapy Research Paper

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

Subcellular localization of FANCD2 is associated with survival in ovarian carcinoma Research Paper

Both BRCA1-wild type and -mutant triple-negative breast cancers show sensitivity to the NAE inhibitor MLN4924 which is enhanced upon MLN4924 and cisplatin combination treatment Research Paper

Sphingomyelin phosphodiesterase 3 methylation and silencing in oral squamous cell carcinoma results in increased migration and invasion and altered stress response Research Paper

Correction: Metabolomic analysis of uterine serous carcinoma with acquired resistance to paclitaxel Correction

Resistance to allosteric SHP2 inhibition in FGFR-driven cancers through rapid feedback activation of FGFR Research Paper

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

Response of a chemo-resistant triple-negative breast cancer patient to a combination of p62-encoding plasmid, Elenagen, and CMF chemotherapy Case Report

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish Research Paper

Exosome mediated miR-155 delivery confers cisplatin chemoresistance in oral cancer cells via epithelial-mesenchymal transition Research Paper

Origin and role of hepatic myofibroblasts in hepatocellular carcinoma Review

Correction: Overexpression of AKR1C3 significantly enhances human prostate cancer cells resistance to radiation Correction

Cancer associated fibroblasts confer shear resistance to circulating tumor cells during prostate cancer metastatic progression Research Paper

The prognostic role of microRNA in epithelial ovarian cancer: a systematic review of literature with an overall survival meta-analysis Review

Early prediction of resistance to tyrosine kinase inhibitors by plasma monitoring of EGFR mutations in NSCLC: a new algorithm for patient selection and personalized treatment Research Paper

Quizartinib, a selective FLT3 inhibitor, maintains antileukemic activity in preclinical models of RAS-mediated midostaurin-resistant acute myeloid leukemia cells Research Paper

Acute promyelocytic leukemia (APL): a review of the literature Review

Glypican-1 in human glioblastoma: implications in tumorigenesis and chemotherapy Research Paper

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

Subcellular localization of FANCD2 is associated with survival in ovarian carcinoma Research Paper

Both BRCA1-wild type and -mutant triple-negative breast cancers show sensitivity to the NAE inhibitor MLN4924 which is enhanced upon MLN4924 and cisplatin combination treatment Research Paper

Sphingomyelin phosphodiesterase 3 methylation and silencing in oral squamous cell carcinoma results in increased migration and invasion and altered stress response Research Paper

Correction: Metabolomic analysis of uterine serous carcinoma with acquired resistance to paclitaxel Correction

Resistance to allosteric SHP2 inhibition in FGFR-driven cancers through rapid feedback activation of FGFR Research Paper

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

Response of a chemo-resistant triple-negative breast cancer patient to a combination of p62-encoding plasmid, Elenagen, and CMF chemotherapy Case Report