The Oncosearch | Oncotarget

Targeted drug combination therapy design based on driver genes Research Paper

Lilian Zsákai, Anna Sipos, Judit Dobos, Dániel Erős, Csaba Szántai-Kis, Péter Bánhegyi, János Pató, László Őrfi, Zsolt Matula, Gábor Mikala, György Kéri, István Peták, István Vályi-Nagy

Published Sep 3, 2019 · Vol. 10, No. 51 · pp. 5255-5266

Keywords: combination therapy, cancer driver gene, primary culture, small molecule compound, multiple myeloma

Safety evaluation of conditionally immortalized cells for renal replacement therapy Research Paper

Milos Mihajlovic, Sam Hariri, Koen C.G. Westphal, Manoe J. Janssen, Miriam J. Oost, Laura Bongiovanni, Lambertus P. van den Heuvel, Alain de Bruin, Luuk B. Hilbrands, Rosalinde Masereeuw

Published Sep 3, 2019 · Vol. 10, No. 51 · pp. 5332-5348

Keywords: bioartificial kidney, cell therapy safety, conditionally immortalized proximal tubule epithelial cells, tumorigenicity, viral integration

Correction: Fibroblast growth factor receptor 4 induced resistance to radiation therapy in colorectal cancer Correction

Mohamed A. Ahmed, Edgar Selzer, Wolfgang Dörr, Gerd Jomrich, Felix Harpain, Gerd R. Silberhumer, Leonhard Müllauer, Klaus Holzmann, Bettina Grasl-Kraupp, Michael Grusch, Walter Berger, Brigitte Marian

Published Aug 29, 2019 · Vol. 10, No. 51 · pp. 5385-5386

DS-1205b, a novel selective inhibitor of AXL kinase, blocks resistance to EGFR-tyrosine kinase inhibitors in a non-small cell lung cancer xenograft model Research Paper

Takeshi Jimbo, Mana Hatanaka, Takahiro Komatsu, Tomoe Taira, Kentaro Kumazawa, Naoyuki Maeda, Takashi Suzuki, Masahiro Ota, Noriyasu Haginoya, Takeshi Isoyama, Kosaku Fujiwara

Published Aug 27, 2019 · Vol. 10, No. 50 · pp. 5152-5167

Keywords: AXL, DS-1205, EGFR-TKI resistance, erlotinib, osimertinib

Detection of tyrosine kinase inhibitors-induced COX-2 expression in bladder cancer by fluorocoxib A Research Paper

Jennifer Bourn, Sony Pandey, Jashim Uddin, Lawrence Marnett, Maria Cekanova

Published Aug 27, 2019 · Vol. 10, No. 50 · pp. 5168-5180

Keywords: bladder cancer, TKIs, RTKIs, COX-2, targeted therapies

A prognostic score for overall survival in patients treated with abiraterone in the pre- and post-chemotherapy setting Research Paper

Martin Boegemann, Katrin Schlack, Lena Früchtenicht, Julie Steinestel, Andres Jan Schrader, Yvonne Wennmann, Laura-Maria Krabbe, Okyaz Eminaga

Published Aug 20, 2019 · Vol. 10, No. 49 · pp. 5082-5091

Keywords: risk score, mCRPC, abiraterone, survival, outcome

TAK228 enhances antitumor activity of eribulin in triple negative breast cancer Research Paper

Nicci Owusu-Brackett, Kurt W. Evans, Argun Akcakanat, Erkan Yuca, Coya Tapia, Yasmeen Qamar Rizvi, Ecaterina Ileana Dumbrava, Filip Janku, Funda Meric-Bernstam

Published Aug 20, 2019 · Vol. 10, No. 49 · pp. 5011-5019

Keywords: breast cancer, TAK228, PI3K, PTEN, TNBC

The p21 levels have the potential to be a monitoring marker for ribociclib in breast cancer Research Paper

Masafumi Iida, Misato Nakamura, Emi Tokuda, Daichi Toyosawa, Toshifumi Niwa, Noriaki Ohuchi, Takanori Ishida, Shin-ichi Hayashi

Published Aug 6, 2019 · Vol. 10, No. 47 · pp. 4907-4918

Keywords: breast cancer, CDK4/6 inhibitor, resistance, CDK6, p21

Combinatorial drug screening of mammary cells with induced mesenchymal transformation to identify drug combinations for triple-negative breast cancer Research Paper

Sierra A. Colavito, James T. Platt, Matthew A. Held, Zongzhi Liu, Ryan Sokup, David F. Stern

Published Aug 6, 2019 · Vol. 10, No. 47 · pp. 4822-4839

Keywords: epithelial-mesenchymal transition, triple-negative breast cancer, targeted drug combination screen, claudin-low breast cancer, CHK1

Tumor-associated macrophages and individual chemo-susceptibility are influenced by iron chelation in human slice cultures of gastric cancer Research Paper

Sebastian Prill, Jakob Rebstock, Anja Tennemann, Justus Körfer, Rasmus Sönnichsen, René Thieme, Ines Gockel, Orestis Lyros, Astrid Monecke, Christian Wittekind, Arved Weimann, Kerstin Grosser, Volker Wiechmann, Christoph Kubick, Ingo Bechmann, Florian Lordick, Sonja Kallendrusch

Published Jul 30, 2019 · Vol. 10, No. 46 · pp. 4731-4742

Keywords: tumor-associated macrophages, tumor slice cultures, deferoxamine, gastric cancer, iron

Oncologist uptake of comprehensive genomic profile guided targeted therapy Research Paper

Mary K. Nesline, Paul DePietro, Grace K. Dy, Amy Early, Antonios Papanicolau-Sengos, Jeffrey M. Conroy, Felicia L. Lenzo, Sean T. Glenn, Hongbin Chen, Anne Grand’Maison, Patrick Boland, Marc S. Ernstoff, Igor Puzanov, Stephen Edge, Stacey Akers, Mateusz Opyrchal, Gurkamal Chatta, Kunle Odunsi, Peter Frederick, Shashikant Lele, Mark Gardner, Carl Morrison

Published Jul 23, 2019 · Vol. 10, No. 45 · pp. 4616-4629

Keywords: comprehensive genomic profiling, targeted therapy, clinical decision making, next-generation sequencing, real world data

Reduced chemotherapeutic sensitivity in high glucose condition: implication of antioxidant response Research Paper

Alessia Garufi, Gianandrea Traversi, Maria Saveria Gilardini Montani, Valerio D’Orazi, Giuseppa Pistritto, Mara Cirone, Gabriella D’Orazi

Published Jul 23, 2019 · Vol. 10, No. 45 · pp. 4691-4702

Keywords: chemoresistance, reactive oxygen species (ROS), high glucose (HG), cancer, nuclear factor erythroid 2-related factor 2 (NRF2)

Photodynamic therapy of cervical cancer by eradication of cervical cancer cells and cervical cancer stem cells Research Paper

Elvin Peter Chizenga, Rahul Chandran, Heidi Abrahamse

Published Jul 9, 2019 · Vol. 10, No. 43 · pp. 4380-4396

Keywords: photodynamic therapy, cervical cancer, cancer stem cells, photosensitizer, cancer resistance

Improvement of the rituximab–induced cell death by potentiation of the store-operated calcium entry in mantle cell lymphoma cell lines Research Paper

Isabelle Doignon, Olivier Fayol, Olivier Dellis

Published Jul 9, 2019 · Vol. 10, No. 43 · pp. 4466-4478

Keywords: mantle cell lymphoma, rituximab, store-operated calcium entry, potentiation, apoptosis

AGR2, a unique tumor-associated antigen, is a promising candidate for antibody targeting Research Paper

Alvin Y. Liu, Adelle D. Kanan, Tomasz P. Radon, Siama Shah, Mark E. Weeks, Julie M. Foster, Jane K. Sosabowski, Laurent Dumartin, Tatjana Crnogorac-Jurcevic

Published Jul 2, 2019 · Vol. 10, No. 42 · pp. 4276-4289

Keywords: pancreatic cancer, eAGR2, chimeric antibody, prostate cancer, tumor localization

PARP-1 inhibitor modulate β-catenin signaling to enhance cisplatin sensitivity in cancer cervix Research Paper

Minakshi Mann, Sachin Kumar, Shyam S. Chauhan, Neerja Bhatla, Sunesh Kumar, Sameer Bakhshi, Ritu Gupta, Ashok Sharma, Lalit Kumar

Published Jul 2, 2019 · Vol. 10, No. 42 · pp. 4262-4275

Keywords: cervical cancer, cisplatin, PARP-1, PJ34, β-catenin

CEMIP upregulates BiP to promote breast cancer cell survival in hypoxia Research Paper

Anna Banach, Ya-Ping Jiang, Eric Roth, Cem Kuscu, Jian Cao, Richard Z. Lin

Published Jul 2, 2019 · Vol. 10, No. 42 · pp. 4307-4320

Keywords: CEMIP, BiP, hypoxia, autophagy

Detecting predictive androgen receptor modifications in circulating prostate cancer cells Clinical Research Papers

Julie Steinestel, Manuel Luedeke, Annette Arndt, Thomas J. Schnoeller, Jochen K. Lennerz, Carina Wurm, Christiane Maier, Marcus V. Cronauer, Konrad Steinestel, Andres J. Schrader

Published Jun 25, 2019 · Vol. 10, No. 41 · pp. 4213-4223

Emerging therapeutic potential of anti-psychotic drugs in the management of human glioma: A comprehensive review Review

Muhamad N.A. Kamarudin, Ishwar Parhar

Published Jun 11, 2019 · Vol. 10, No. 39 · pp. 3952-3977

Keywords: glioma, anti-psychotic drugs, typical anti-psychotic, atypical anti-psychotic, valproic acid

Correction: Infiltrating mast cells increase prostate cancer chemotherapy and radiotherapy resistances via modulation of p38/p53/p21 and ATM signals Correction

Hongjun Xie, Chong Li, Qiang Dang, Luke S. Chang, Lei Li

Published Jun 6, 2019 · Vol. 10, No. 39 · pp. 3978-3978

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

Targeted drug combination therapy design based on driver genes Research Paper

Safety evaluation of conditionally immortalized cells for renal replacement therapy Research Paper

Correction: Fibroblast growth factor receptor 4 induced resistance to radiation therapy in colorectal cancer Correction

DS-1205b, a novel selective inhibitor of AXL kinase, blocks resistance to EGFR-tyrosine kinase inhibitors in a non-small cell lung cancer xenograft model Research Paper

Detection of tyrosine kinase inhibitors-induced COX-2 expression in bladder cancer by fluorocoxib A Research Paper

A prognostic score for overall survival in patients treated with abiraterone in the pre- and post-chemotherapy setting Research Paper

TAK228 enhances antitumor activity of eribulin in triple negative breast cancer Research Paper

The p21 levels have the potential to be a monitoring marker for ribociclib in breast cancer Research Paper

Combinatorial drug screening of mammary cells with induced mesenchymal transformation to identify drug combinations for triple-negative breast cancer Research Paper

Tumor-associated macrophages and individual chemo-susceptibility are influenced by iron chelation in human slice cultures of gastric cancer Research Paper

Oncologist uptake of comprehensive genomic profile guided targeted therapy Research Paper

Reduced chemotherapeutic sensitivity in high glucose condition: implication of antioxidant response Research Paper

Photodynamic therapy of cervical cancer by eradication of cervical cancer cells and cervical cancer stem cells Research Paper

Improvement of the rituximab–induced cell death by potentiation of the store-operated calcium entry in mantle cell lymphoma cell lines Research Paper

AGR2, a unique tumor-associated antigen, is a promising candidate for antibody targeting Research Paper

PARP-1 inhibitor modulate β-catenin signaling to enhance cisplatin sensitivity in cancer cervix Research Paper

CEMIP upregulates BiP to promote breast cancer cell survival in hypoxia Research Paper

Detecting predictive androgen receptor modifications in circulating prostate cancer cells Clinical Research Papers

Emerging therapeutic potential of anti-psychotic drugs in the management of human glioma: A comprehensive review Review

Correction: Infiltrating mast cells increase prostate cancer chemotherapy and radiotherapy resistances via modulation of p38/p53/p21 and ATM signals Correction

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Targeted drug combination therapy design based on driver genes Research Paper

Safety evaluation of conditionally immortalized cells for renal replacement therapy Research Paper

Correction: Fibroblast growth factor receptor 4 induced resistance to radiation therapy in colorectal cancer Correction

DS-1205b, a novel selective inhibitor of AXL kinase, blocks resistance to EGFR-tyrosine kinase inhibitors in a non-small cell lung cancer xenograft model Research Paper

Detection of tyrosine kinase inhibitors-induced COX-2 expression in bladder cancer by fluorocoxib A Research Paper

A prognostic score for overall survival in patients treated with abiraterone in the pre- and post-chemotherapy setting Research Paper

TAK228 enhances antitumor activity of eribulin in triple negative breast cancer Research Paper

The p21 levels have the potential to be a monitoring marker for ribociclib in breast cancer Research Paper

Combinatorial drug screening of mammary cells with induced mesenchymal transformation to identify drug combinations for triple-negative breast cancer Research Paper

Tumor-associated macrophages and individual chemo-susceptibility are influenced by iron chelation in human slice cultures of gastric cancer Research Paper

Oncologist uptake of comprehensive genomic profile guided targeted therapy Research Paper

Reduced chemotherapeutic sensitivity in high glucose condition: implication of antioxidant response Research Paper

Photodynamic therapy of cervical cancer by eradication of cervical cancer cells and cervical cancer stem cells Research Paper

Improvement of the rituximab–induced cell death by potentiation of the store-operated calcium entry in mantle cell lymphoma cell lines Research Paper

AGR2, a unique tumor-associated antigen, is a promising candidate for antibody targeting Research Paper

PARP-1 inhibitor modulate β-catenin signaling to enhance cisplatin sensitivity in cancer cervix Research Paper

CEMIP upregulates BiP to promote breast cancer cell survival in hypoxia Research Paper

Detecting predictive androgen receptor modifications in circulating prostate cancer cells Clinical Research Papers

Emerging therapeutic potential of anti-psychotic drugs in the management of human glioma: A comprehensive review Review

Correction: Infiltrating mast cells increase prostate cancer chemotherapy and radiotherapy resistances via modulation of p38/p53/p21 and ATM signals Correction