The Oncosearch | Oncotarget

Ferroptosis of epithelial ovarian cancer: genetic determinants and therapeutic potential Research Perspective

Chao-Chieh Lin, Jen-Tsan Chi

Published Sep 9, 2020 · Vol. 11, No. 39 · pp. 3562-3570

Keywords: ferroptosis, cystine, ovarian cancer, GPX4, NADPH oxidase

AKT isoforms have discrete expression in triple negative breast cancers and roles in cisplatin sensitivity Research Paper

Bhumika Wadhwa, Masroor Paddar, Sameer Khan, Sameer Mir, Philip A.Clarke, Anna M. Grabowska, Devanahalli G. Vijay, Fayaz Malik

Published Sep 8, 2020 · Vol. 11, No. 45 · pp. 4178-4194

Keywords: AKT isoform, CSCs, ABCG2, drug resistance, TNBCs

Small ceramide tames big p53 mutant beast Editorial

Ronald A. Hill, Zhijun Liu, Yong-Yu Liu

Published Sep 1, 2020 · Vol. 11, No. 37 · pp. 3418-3419

Keywords: ceramide, p53 tumor suppressor, missense mutation, nanomicelle, drug resistance

Deconstructing tumor heterogeneity: the stromal perspective Meeting Report

Renee E. Vickman, Douglas V. Faget, Philip Beachy, David Beebe, Neil A. Bhowmick, Edna Cukierman, Wu-Min Deng, James G. Granneman, Jeffrey Hildesheim, Raghu Kalluri, Ken S. Lau, Ernst Lengyel, Joakim Lundeberg, Jorge Moscat, Peter S. Nelson, Kristian Pietras, Katerina Politi, Ellen Puré, Ruth Scherz-Shouval, Mara H. Sherman, David Tuveson, Ashani T. Weeraratna, Richard M. White, Melissa H. Wong, Elisa C. Woodhouse, Ying Zheng, Simon W. Hayward, Sheila A. Stewart

Published Aug 29, 2020 · Vol. 11, No. 40 · pp. 3621-3632

Keywords: tumor microenvironment, stromal heterogeneity, extracellular matrix, cellular plasticity, therapy resistance

ATM inhibition overcomes resistance to histone deacetylase inhibitor due to p21 induction and cell cycle arrest Research Paper

Luigi Scotto, Xavier J. Serrano, Kelly Zullo, Cristina Kinahan, Changchun Deng, Ahmed Sawas, Susan Bates, Owen A. O’Connor

Published Aug 18, 2020 · Vol. 11, No. 37 · pp. 3432-3442

Keywords: lymphoma, HDAC inhibitor, ATM inhibitor, p21, cell cycle

The bromodomain inhibitor IBET-151 attenuates vismodegib-resistant esophageal adenocarcinoma growth through reduction of GLI signaling Research Paper

Annamil Alvarez-Trotta, Zhiqiang Wang, Elena Shersher, Bin Li, Jun Long, Ines Lohse, Claes Wahlestedt, Wael El-Rifai, David J. Robbins, Anthony J. Capobianco

Published Jul 28, 2020 · Vol. 11, No. 33 · pp. 3174-3187

Keywords: IBET-151, esophageal adenocarcinoma, GDC-0449 resistance, patient-derived xenografts, Hedgehog/GLI signaling pathway

Important players in carcinogenesis as potential targets in cancer therapy: an update Review

Justyna Magdalena Hermanowicz, Iwona Kwiatkowska, Dariusz Pawlak

Published Jul 21, 2020 · Vol. 11, No. 32 · pp. 3078-3101

Keywords: modulators of carcinogenesis, acetylcholine, peroxisome proliferator-activated receptors, aquaporins

Paradox breaker BRAF inhibitors have comparable potency and MAPK pathway reactivation to encorafenib in BRAF mutant colorectal cancer Research Paper

Oliver J. Pickles, Aneta Drozd, Louise Tee, Andrew D. Beggs, Gary W. Middleton

Published Jul 13, 2020 · Vol. 11, No. 34 · pp. 3188-3197

Keywords: colorectal cancer, BRAF, paradox breaker, encorafenib, PLX8394

Working together for the family: determination of HER oncogene co-amplifications in breast cancer Research Paper

Sergio Laurito, María Teresita Branham, Emanuel Campoy, Sebastián Real, Juan Cueto, Guillermo Urrutia, Francisco Gago, Olga Tello, Telma Glatstein, Paola De la Iglesia, Lilit Atanesyan, Suvi Savola, Maria Roqué

Published Jun 29, 2020 · Vol. 11, No. 28 · pp. 2774-2792

Keywords: HER oncogenes, breast cancer, MLPA, digital PCR, co-amplification

TAF15 contributes to the radiation-inducible stress response in cancer Research Paper

Abhay Kumar Singh, Vaishali Kapoor, Dinesh Thotala, Dennis E. Hallahan

Published Jun 22, 2020 · Vol. 11, No. 27 · pp. 2647-2659

Keywords: TAF15, radiation inducible, lung cancer, antibody

Genomic markers of midostaurin drug sensitivity in FLT3 mutated and FLT3 wild-type acute myeloid leukemia patients Research Paper

Mara W. Rosenberg, Kevin Watanabe-Smith, Jeffrey W. Tyner, Cristina E. Tognon, Brian J. Druker, Uma Borate

Published Jun 17, 2020 · Vol. 11, No. 29 · pp. 2807-2818

Keywords: acute myeloid leukemia, drug sensitivity, midostaurin, drug resistance, FLT3

Epigenetic feedback and stochastic partitioning during cell division can drive resistance to EMT Research Paper

Wen Jia, Shubham Tripathi, Priyanka Chakraborty, Adithya Chedere, Annapoorni Rangarajan, Herbert Levine, Mohit Kumar Jolly

Published Jun 11, 2020 · Vol. 11, No. 27 · pp. 2611-2624

Keywords: epithelial-mesenchymal transition, mesenchymal-epithelial transition, GRHL2, epigenetics, asymmetric cell division

Potential use of lenvatinib for patients with unresectable hepatocellular carcinoma including after treatment with sorafenib: Real-world evidence and in vitro assessment via protein phosphorylation array Research Paper

Tetsu Tomonari, Yasushi Sato, Hironori Tanaka, Takahiro Tanaka, Yasuteru Fujino, Yasuhiro Mitsui, Akihiro Hirao, Tatsuya Taniguchi, Koichi Okamoto, Masahiro Sogabe, Hiroshi Miyamoto, Naoki Muguruma, Harumi Kagiwada, Masashi Kitazawa, Kazuhiko Fukui, Katsuhisa Horimoto, Tetsuji Takayama

Published Jun 8, 2020 · Vol. 11, No. 26 · pp. 2531-2542

Keywords: hepatocellular carcinoma, lenvatinib, sorafenib, hepatic reserve function, FGFR

Correction: Cepharanthine hydrochloride reverses the mdr1 (P-glycoprotein)-mediated esophageal squamous cell carcinoma cell cisplatin resistance through JNK and p53 signals Correction

Pengjun Zhou, Rong Zhang, Ying Wang, Dandan Xu, Li Zhang, Jinhong Qin, Guifeng Su, Yue Feng, Hongce Chen, Siyuan You, Wen Rui, Huizhong Liu, Suhong Chen, Hongyuan Chen, Yifei Wang

Published Jun 4, 2020 · Vol. 12, No. 1 · pp. 61-62

RSK inhibitor BI-D1870 inhibits acute myeloid leukemia cell proliferation by targeting mitotic exit Research Paper

Hee-Don Chae, Ritika Dutta, Bruce Tiu, Fieke W. Hoff, Benedetta Accordi, Valentina Serafin, Minyoung Youn, Min Huang, Nathan Sumarsono, Kara L. Davis, Norman J. Lacayo, Martina Pigazzi, Terzah M. Horton, Steven M. Kornblau, Kathleen M. Sakamoto

Published May 26, 2020 · Vol. 11, No. 25 · pp. 2387-2403

Keywords: acute myeloid leukemia, BI-D1870, RSK, vincristine, spindle assembly checkpoint

Discovery of fifteen new geroprotective plant extracts and identification of cellular processes they affect to prolong the chronological lifespan of budding yeast Research Paper

Pamela Dakik, Monica Enith Lozano Rodriguez, Jennifer Anne Baratang Junio, Darya Mitrofanova, Younes Medkour, Tala Tafakori, Tarek Taifour, Vicky Lutchman, Eugenie Samson, Anthony Arlia-Ciommo, Belise Rukundo, Éric Simard, Vladimir I. Titorenko

Published May 23, 2020 · Vol. 11, No. 23 · pp. 2182-2203

Keywords: cellular aging, longevity, gerotargets, geroprotectors, plant extracts

Nucleolin represses transcription of the androgen receptor gene through a G-quadruplex Research Paper

Cindy K. Miranti, Sara Moore, Yongeun Kim, Venkateshwar Reddy Chappeta, Kui Wu, Biswanath De, Vijay Gokhale, Laurence H. Hurley, Elsa M. Reyes-Reyes

Published Apr 26, 2020 · Vol. 11, No. 19 · pp. 1758-1776

Keywords: prostate cancer, androgen receptor, nucleolin, gene repression, G-quadruplex

Expression of receptor activator of NFkB (RANK) drives stemness and resistance to therapy in ER+HER2- breast cancer Research Paper

Inês Gomes, Bernardo P. de Almeida, Sara Dâmaso, André Mansinho, Inês Correia, Sara Henriques, Raquel Cruz-Duarte, Guilherme Vilhais, Pedro Félix, Patrícia Alves, Patrícia Corredeira, Nuno L. Barbosa-Morais, Luis Costa, Sandra Casimiro

Published Apr 18, 2020 · Vol. 11, No. 19 · pp. 1714-1728

Keywords: RANKL-RANK pathway, ER+ breast cancer, resistance to chemo and hormone therapy, stemness, metastization

Exosome-mediated delivery of miR-30a sensitize cisplatin-resistant variant of oral squamous carcinoma cells via modulating Beclin1 and Bcl2 Research Paper

Bhagyashri Kulkarni, Piyush Gondaliya, Prathibha Kirave, Rakesh Rawal, Alok Jain, Rachana Garg, Kiran Kalia

Published Apr 2, 2020 · Vol. 11, No. 20 · pp. 1832-1845

Keywords: chemoresistance, miRNA30a-5p, exosomes, oral cancer, autophagy

Transcriptional regulation of HSPB1 by Friend leukemia integration-1 factor modulates radiation and temozolomide resistance in glioblastoma Priority Research Paper

Yetirajam Rajesh, Angana Biswas, Payel Banik, Ipsita Pal, Subhayan Das, Sachin A. Borkar, Hardik Sardana, Abhijit Saha, Swadesh K. Das, Luni Emdad, Paul B. Fisher, Mahitosh Mandal

Published Mar 31, 2020 · Vol. 11, No. 13 · pp. 1097-1108

Keywords: HSPB1, RNAseq, Fli-1, radioresistant GBM, temozolomide resistant GBM

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Ferroptosis of epithelial ovarian cancer: genetic determinants and therapeutic potential Research Perspective

AKT isoforms have discrete expression in triple negative breast cancers and roles in cisplatin sensitivity Research Paper

Small ceramide tames big p53 mutant beast Editorial

Deconstructing tumor heterogeneity: the stromal perspective Meeting Report

ATM inhibition overcomes resistance to histone deacetylase inhibitor due to p21 induction and cell cycle arrest Research Paper

The bromodomain inhibitor IBET-151 attenuates vismodegib-resistant esophageal adenocarcinoma growth through reduction of GLI signaling Research Paper

Important players in carcinogenesis as potential targets in cancer therapy: an update Review

Paradox breaker BRAF inhibitors have comparable potency and MAPK pathway reactivation to encorafenib in BRAF mutant colorectal cancer Research Paper

Working together for the family: determination of HER oncogene co-amplifications in breast cancer Research Paper

TAF15 contributes to the radiation-inducible stress response in cancer Research Paper

Genomic markers of midostaurin drug sensitivity in FLT3 mutated and FLT3 wild-type acute myeloid leukemia patients Research Paper

Epigenetic feedback and stochastic partitioning during cell division can drive resistance to EMT Research Paper

Potential use of lenvatinib for patients with unresectable hepatocellular carcinoma including after treatment with sorafenib: Real-world evidence and in vitro assessment via protein phosphorylation array Research Paper

Correction: Cepharanthine hydrochloride reverses the mdr1 (P-glycoprotein)-mediated esophageal squamous cell carcinoma cell cisplatin resistance through JNK and p53 signals Correction

RSK inhibitor BI-D1870 inhibits acute myeloid leukemia cell proliferation by targeting mitotic exit Research Paper

Discovery of fifteen new geroprotective plant extracts and identification of cellular processes they affect to prolong the chronological lifespan of budding yeast Research Paper

Nucleolin represses transcription of the androgen receptor gene through a G-quadruplex Research Paper

Expression of receptor activator of NFkB (RANK) drives stemness and resistance to therapy in ER+HER2- breast cancer Research Paper

Exosome-mediated delivery of miR-30a sensitize cisplatin-resistant variant of oral squamous carcinoma cells via modulating Beclin1 and Bcl2 Research Paper

Transcriptional regulation of HSPB1 by Friend leukemia integration-1 factor modulates radiation and temozolomide resistance in glioblastoma Priority Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Ferroptosis of epithelial ovarian cancer: genetic determinants and therapeutic potential Research Perspective

AKT isoforms have discrete expression in triple negative breast cancers and roles in cisplatin sensitivity Research Paper

Small ceramide tames big p53 mutant beast Editorial

Deconstructing tumor heterogeneity: the stromal perspective Meeting Report

ATM inhibition overcomes resistance to histone deacetylase inhibitor due to p21 induction and cell cycle arrest Research Paper

The bromodomain inhibitor IBET-151 attenuates vismodegib-resistant esophageal adenocarcinoma growth through reduction of GLI signaling Research Paper

Important players in carcinogenesis as potential targets in cancer therapy: an update Review

Paradox breaker BRAF inhibitors have comparable potency and MAPK pathway reactivation to encorafenib in BRAF mutant colorectal cancer Research Paper

Working together for the family: determination of HER oncogene co-amplifications in breast cancer Research Paper

TAF15 contributes to the radiation-inducible stress response in cancer Research Paper

Genomic markers of midostaurin drug sensitivity in FLT3 mutated and FLT3 wild-type acute myeloid leukemia patients Research Paper

Epigenetic feedback and stochastic partitioning during cell division can drive resistance to EMT Research Paper

Potential use of lenvatinib for patients with unresectable hepatocellular carcinoma including after treatment with sorafenib: Real-world evidence and in vitro assessment via protein phosphorylation array Research Paper

Correction: Cepharanthine hydrochloride reverses the mdr1 (P-glycoprotein)-mediated esophageal squamous cell carcinoma cell cisplatin resistance through JNK and p53 signals Correction

RSK inhibitor BI-D1870 inhibits acute myeloid leukemia cell proliferation by targeting mitotic exit Research Paper

Discovery of fifteen new geroprotective plant extracts and identification of cellular processes they affect to prolong the chronological lifespan of budding yeast Research Paper

Nucleolin represses transcription of the androgen receptor gene through a G-quadruplex Research Paper

Expression of receptor activator of NFkB (RANK) drives stemness and resistance to therapy in ER+HER2- breast cancer Research Paper

Exosome-mediated delivery of miR-30a sensitize cisplatin-resistant variant of oral squamous carcinoma cells via modulating Beclin1 and Bcl2 Research Paper

Transcriptional regulation of HSPB1 by Friend leukemia integration-1 factor modulates radiation and temozolomide resistance in glioblastoma Priority Research Paper