The Oncosearch | Oncotarget

Inhibition of Lon blocks cell proliferation, enhances chemosensitivity by promoting apoptosis and decreases cellular bioenergetics of bladder cancer: potential roles of Lon as a prognostic marker and therapeutic target in baldder cancer Research Paper

Yongzhang Liu, Linhua Lan, Kate Huang, Rongrong Wang, Cuicui Xu, Yang Shi, Xiaoyi Wu, Zhi Wu, Jiliang Zhang, Lin Chen, Lu Wang, Xiaomin Yu, Haibo Zhu, Bin Lu

Published May 28, 2014 · Vol. 5, No. 22 · pp. 11209-11224

GSK-3 as potential target for therapeutic intervention in cancer Review

James A. McCubrey, Linda S. Steelman, Fred E. Bertrand, Nicole M. Davis, Melissa Sokolosky, Steve L. Abrams, Giuseppe Montalto, Antonino B. Dâ€™Assoro, Massimo Libra, Ferdinando Nicoletti, Roberta Maestro, Jorg Basecke, Dariusz Rakus, Agnieszka Gizak, Zoya Demidenko, Lucio Cocco, Alberto M. Martelli, Melchiorre Cervello

Published May 28, 2014 · Vol. 5, No. 10 · pp. 2881-2911

Targeting tyrosine-kinases and estrogen receptor abrogates resistance to endocrine therapy in breast cancer Research Paper

Shuying Liu, Xiaolong Meng, Huiqin Chen, Wenbin Liu, Todd Miller, Mandi Murph Yiling Lu, Fan Zhang, Mihai Gagea, Carlos L. Arteaga, Gordon B. Mills, Funda Meric-Bernstam, Ana M. GonzÃ¡lez-Angulo

Published May 27, 2014 · Vol. 5, No. 19 · pp. 9049-9064

Cancer stem cells from epithelial ovarian cancer patients privilege oxidative phosphorylation, and resist glucose deprivation Research Paper

Anna PastÃ², Chiara Bellio, Giorgia Pilotto, Vincenzo Ciminale, Micol Silic-Benussi, Giulia Guzzo, Andrea Rasola, Chiara Frasson, Giorgia Nardo, Elisabetta Zulato, Maria Ornella Nicoletto, Mariangela Manicone, Stefano Indraccolo, Alberto Amadori

Published May 26, 2014 · Vol. 5, No. 12 · pp. 4305-4319

Snail regulates Nanog status during the epithelialâ€“mesenchymal transition via the Smad1/Akt/GSK3Î² signaling pathway in non-small-cell lung cancer Research Paper

Chen-Wei Liu, Ching-Hao Li, Yi-Jen Peng, Yu-Wen Cheng, Huei-Wen Chen, Po-Lin Liao, Jaw-Jou Kang, Mao-Hsiung Yen

Published May 26, 2014 · Vol. 5, No. 11 · pp. 3880-3894

Selenocysteine derivative overcomes TRAIL resistance in melanoma cells: evidence for ROS-dependent synergism and signaling crosstalk Research Paper

Wenqiang Cao, Xiaoling Li, Shanyuan Zheng, Wenjie Zheng, Yum-shing Wong, Tianfeng Chen

Published May 26, 2014 · Vol. 5, No. 17 · pp. 7431-7445

Relevance of IGFBP2 proteolysis in glioma and contribution of the extracellular protease ADAMTS1 Research Paper

EstefanÃa Martino-Echarri, RubÃ©n FernÃ¡ndez-RodrÃguez, Joan Josep Bech-Serra, MarÃa del Carmen Plaza-Calonge, Noemi Vidal, Carmen Casal, Nuria ColomÃ©, Joan Seoane, Francesc Canals, Juan Carlos RodrÃguez-Manzaneque

Published May 26, 2014 · Vol. 5, No. 12 · pp. 4295-4304

DNA intercalator BMH-21 inhibits RNA polymerase I independent of DNA damage response Research Paper

Laureen Colis, Karita Peltonen, Paul Sirajuddin, Hester Liu, Sara Sanders, Glen Ernst, James C. Barrow, Marikki Laiho

Published May 26, 2014 · Vol. 5, No. 12 · pp. 4361-4369

Identification of a ternary protein-complex as a therapeutic target for K-Ras-dependent colon cancer Research Paper

Xiaomei Qi, Congying Xie, Songwang Hou, Gang Li, Ning Yin, Lei Dong, Adrienne Lepp, Marla A. Chesnik, Shama P. Mirza, Aniko Szabo, Susan Tsai, Zainab Basir, Shixiu Wu, Guan Chen

Published May 25, 2014 · Vol. 5, No. 12 · pp. 4269-4282

Increased Nek1 expression in Renal Cell Carcinoma cells is associated with decreased sensitivity to DNA-damaging treatment Research Paper

Yumay Chen, Chi-Fen Chen, Rosaria Polci, Randy Wei, Daniel J. Riley, Phang-Lang Chen

Published May 25, 2014 · Vol. 5, No. 12 · pp. 4283-4294

Histone deacetylase 2 and N-Myc reduce p53 protein phosphorylation at serine 46 by repressing gene transcription of tumor protein 53-induced nuclear protein 1 Research Paper

Jeyran Shahbazi, Christopher J. Scarlett, Murray D. Norris, Bing Liu, Michelle Haber, Andrew E. Tee, Alice Carrier, Andrew V. Biankin, Wendy B. London, Glenn M. Marshall, Richard B. Lock, Tao Liu

Published May 20, 2014 · Vol. 5, No. 12 · pp. 4257-4268

ROS-mediated EB1 phosphorylation through Akt/GSK3Î² pathway: implication in cancer cell response to microtubule-targeting agents Research Paper

Marion Le Grand, Amandine Rovini, Veronique Bourgarel-Rey, Stephane Honore, Sonia Bastonero, Diane Braguer, Manon Carre

Published May 18, 2014 · Vol. 5, No. 10 · pp. 3408-3423

Post-translational regulation of COX2 activity by FYN in prostate cancer cells Research Paper

Anna Alexanian, Bradley Miller, Marla Chesnik, Shama Mirza, Andrey Sorokin

Published May 18, 2014 · Vol. 5, No. 12 · pp. 4232-4243

Quantitative network mapping of the human kinome interactome reveals new clues for rational kinase inhibitor discovery and individualized cancer therapy Research Paper

Feixiong Cheng, Peilin Jia, Quan Wang, Zhongming Zhao

Published May 18, 2014 · Vol. 5, No. 11 · pp. 3697-3710

Î²1, 4-N-acetylgalactosaminyltransferase III modulates cancer stemness through EGFR signaling pathway in colon cancer cells Research Paper

Mei-Ieng Che, John Huang, Ji-Shiang Hung, Yo-Chuen Lin, Miao-Juei Huang, Hong-Shiee Lai, Wen-Ming Hsu, Jin-Tung Liang, Min-Chuan Huang

Published May 18, 2014 · Vol. 5, No. 11 · pp. 3673-3684

Targeting Phosphatidylinositide3-Kinase/Akt pathway by BKM120 for radiosensitization in hepatocellular carcinoma Research Paper

Wei-Lin Liu, Ming Gao, Kai-Yuan Tzen, Chiao-Ling Tsai, Feng-Ming Hsu, Ann-Lii Cheng, Jason Chia-Hsien Cheng

Published May 16, 2014 · Vol. 5, No. 11 · pp. 3662-3672

SCF^Î²-TRCP regulates osteoclastogenesis via promoting CYLD ubiquitination Research Paper

Xiaomian Wu, Hidefumi Fukushima, Brian J. North, Yoshiyuki Nagaoka, Katsuyuki Nagashima, Feng Deng, Koji Okabe, Hiroyuki Inuzuka, Wenyi Wei

Published May 14, 2014 · Vol. 5, No. 12 · pp. 4211-4221

Adiponectin promotes pancreatic cancer progression by inhibiting apoptosis via the activation of AMPK/Sirt1/PGC-1Î± signaling Research Paper

Bingqing Huang, Xixi Cheng, Dan Wang, Meiyu Peng, Zhenyi Xue, Yurong Da, Ning Zhang, Zhi Yao, Min Li, Aimin Xu, Rongxin Zhang

Published May 13, 2014 · Vol. 5, No. 13 · pp. 4732-4745

Phosphorylation of ribosomal protein S6 confers PARP inhibitor resistance in BRCA1-deficient cancers Research Paper

Chong-kui Sun, Fan Zhang, Tao Xiang, Qianming Chen, Tej K. Pandita, Yuping Huang, Mickey C.T. Hu, Qin Yang

Published May 8, 2014 · Vol. 5, No. 10 · pp. 3375-3385

ADAM10 mediates trastuzumab resistance and is correlated with survival in HER2 positive breast cancer Research Paper

Katharina Feldinger, Daniele Generali, Gabriela Kramer-Marek, Merel Gijsen, Tzi Bun Ng, Jack Ho Wong, Carla Strina, Mariarosa Cappelletti, Daniele Andreis, Ji-Liang Li, Esther Bridges, Helen Turley, Russell Leek, Ioannis Roxanis, Jacek Capala, Gillian Murphy, Adrian L. Harris, Anthony Kong

Published May 8, 2014 · Vol. 5, No. 16 · pp. 6633-6646

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

Inhibition of Lon blocks cell proliferation, enhances chemosensitivity by promoting apoptosis and decreases cellular bioenergetics of bladder cancer: potential roles of Lon as a prognostic marker and therapeutic target in baldder cancer Research Paper

GSK-3 as potential target for therapeutic intervention in cancer Review

Targeting tyrosine-kinases and estrogen receptor abrogates resistance to endocrine therapy in breast cancer Research Paper

Cancer stem cells from epithelial ovarian cancer patients privilege oxidative phosphorylation, and resist glucose deprivation Research Paper

Snail regulates Nanog status during the epithelialâ€“mesenchymal transition via the Smad1/Akt/GSK3Î² signaling pathway in non-small-cell lung cancer Research Paper

Selenocysteine derivative overcomes TRAIL resistance in melanoma cells: evidence for ROS-dependent synergism and signaling crosstalk Research Paper

Relevance of IGFBP2 proteolysis in glioma and contribution of the extracellular protease ADAMTS1 Research Paper

DNA intercalator BMH-21 inhibits RNA polymerase I independent of DNA damage response Research Paper

Identification of a ternary protein-complex as a therapeutic target for K-Ras-dependent colon cancer Research Paper

Increased Nek1 expression in Renal Cell Carcinoma cells is associated with decreased sensitivity to DNA-damaging treatment Research Paper

Histone deacetylase 2 and N-Myc reduce p53 protein phosphorylation at serine 46 by repressing gene transcription of tumor protein 53-induced nuclear protein 1 Research Paper

ROS-mediated EB1 phosphorylation through Akt/GSK3Î² pathway: implication in cancer cell response to microtubule-targeting agents Research Paper

Post-translational regulation of COX2 activity by FYN in prostate cancer cells Research Paper

Quantitative network mapping of the human kinome interactome reveals new clues for rational kinase inhibitor discovery and individualized cancer therapy Research Paper

Î²1, 4-N-acetylgalactosaminyltransferase III modulates cancer stemness through EGFR signaling pathway in colon cancer cells Research Paper

Targeting Phosphatidylinositide3-Kinase/Akt pathway by BKM120 for radiosensitization in hepatocellular carcinoma Research Paper

SCF^Î²-TRCP regulates osteoclastogenesis via promoting CYLD ubiquitination Research Paper

Adiponectin promotes pancreatic cancer progression by inhibiting apoptosis via the activation of AMPK/Sirt1/PGC-1Î± signaling Research Paper

Phosphorylation of ribosomal protein S6 confers PARP inhibitor resistance in BRCA1-deficient cancers Research Paper

ADAM10 mediates trastuzumab resistance and is correlated with survival in HER2 positive breast cancer Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Inhibition of Lon blocks cell proliferation, enhances chemosensitivity by promoting apoptosis and decreases cellular bioenergetics of bladder cancer: potential roles of Lon as a prognostic marker and therapeutic target in baldder cancer Research Paper

GSK-3 as potential target for therapeutic intervention in cancer Review

Targeting tyrosine-kinases and estrogen receptor abrogates resistance to endocrine therapy in breast cancer Research Paper

Cancer stem cells from epithelial ovarian cancer patients privilege oxidative phosphorylation, and resist glucose deprivation Research Paper

Snail regulates Nanog status during the epithelialâ€“mesenchymal transition via the Smad1/Akt/GSK3Î² signaling pathway in non-small-cell lung cancer Research Paper

Selenocysteine derivative overcomes TRAIL resistance in melanoma cells: evidence for ROS-dependent synergism and signaling crosstalk Research Paper

Relevance of IGFBP2 proteolysis in glioma and contribution of the extracellular protease ADAMTS1 Research Paper

DNA intercalator BMH-21 inhibits RNA polymerase I independent of DNA damage response Research Paper

Identification of a ternary protein-complex as a therapeutic target for K-Ras-dependent colon cancer Research Paper

Increased Nek1 expression in Renal Cell Carcinoma cells is associated with decreased sensitivity to DNA-damaging treatment Research Paper

Histone deacetylase 2 and N-Myc reduce p53 protein phosphorylation at serine 46 by repressing gene transcription of tumor protein 53-induced nuclear protein 1 Research Paper

ROS-mediated EB1 phosphorylation through Akt/GSK3Î² pathway: implication in cancer cell response to microtubule-targeting agents Research Paper

Post-translational regulation of COX2 activity by FYN in prostate cancer cells Research Paper

Quantitative network mapping of the human kinome interactome reveals new clues for rational kinase inhibitor discovery and individualized cancer therapy Research Paper

Î²1, 4-N-acetylgalactosaminyltransferase III modulates cancer stemness through EGFR signaling pathway in colon cancer cells Research Paper

Targeting Phosphatidylinositide3-Kinase/Akt pathway by BKM120 for radiosensitization in hepatocellular carcinoma Research Paper

SCFÎ²-TRCP regulates osteoclastogenesis via promoting CYLD ubiquitination Research Paper

Adiponectin promotes pancreatic cancer progression by inhibiting apoptosis via the activation of AMPK/Sirt1/PGC-1Î± signaling Research Paper

Phosphorylation of ribosomal protein S6 confers PARP inhibitor resistance in BRCA1-deficient cancers Research Paper

ADAM10 mediates trastuzumab resistance and is correlated with survival in HER2 positive breast cancer Research Paper

SCF^Î²-TRCP regulates osteoclastogenesis via promoting CYLD ubiquitination Research Paper