The Oncosearch | Oncotarget

PRK1/PKN1 controls migration and metastasis of androgen-independent prostate cancer cells Research Paper

Cordula A. Jilg, Anett Ketscher, Eric Metzger, Barbara Hummel, Dominica Willmann, Vanessa RÃ¼sseler, Vanessa Drendel, Axel Imhof, Manfred Jung, Henriette Franz, Stefanie HÃ¶lz, Malte KrÃ¶nig, Judith M. MÃ¼ller, Roland SchÃ¼le

Published Dec 10, 2014 · Vol. 5, No. 24 · pp. 12646-12664

Î³-H2AX promotes hepatocellular carcinoma angiogenesis via EGFR/HIF-1Î±/VEGF pathways under hypoxic condition Research Paper

Heng Xiao, Rongliang Tong, Chaofeng Ding, Zhen Lv, Chengli Du, Chuanhui Peng, Shaobing Cheng, Haiyang Xie, Lin Zhou, Jian Wu, Shusen Zheng

Published Dec 10, 2014 · Vol. 6, No. 4 · pp. 2180-2192

Inhibition of HIF-1Î± by PX-478 enhances the anti-tumor effect of gemcitabine by inducing immunogenic cell death in pancreatic ductal adenocarcinoma Research Paper

Tiansuo Zhao, He Ren, Li Jia, Jing Chen, Wen Xin, Fan Yan, Jing Li, Xiuchao Wang, Song Gao, Dong Qian, Chongbiao Huang, Jihui Hao

Published Dec 10, 2014 · Vol. 6, No. 4 · pp. 2250-2262

The PI3K inhibitor GDC-0941 displays promising in vitro and in vivo efficacy for targeted medulloblastoma therapy Research Paper

Michael Ehrhardt, Rogerio B. Craveiro, Martin I. Holst, Torsten Pietsch, Dagmar Dilloo

Published Dec 6, 2014 · Vol. 6, No. 2 · pp. 802-813

Keywords: medulloblastoma, GDC-0941, PI3K inhibitor, targeted therapy, c-myc

The activity regulation of the mitotic centromere-associated kinesin by Polo-like kinase 1 Research Paper

Andreas Ritter, Mourad Sanhaji, Kerstin SteinhÃ¤user, Susanne Roth, Frank Louwen, Juping Yuan

Published Dec 2, 2014 · Vol. 6, No. 9 · pp. 6641-6655

Targeting of hyperactivated mTOR signaling in high-risk acute lymphoblastic leukemia in a pre-clinical model Priority Research Paper

Md. Nabiul Hasan, Manon Queudeville, Luca Trentin, Sarah Mirjam Eckhoff, Ilaria Bronzini, Chiara Palmi, Thomas Barth, Giovanni Cazzaniga, Geertruy te Kronnie, Klaus-Michael Debatin, LÃ¼der Hinrich Meyer

Published Dec 2, 2014 · Vol. 6, No. 3 · pp. 1382-1395

Thymidine phosphorylase activates NFÎºB and stimulates the expression of angiogenic and metastatic factors in human cancer cells Research Paper

Sho Tabata, Ryuji Ikeda, Masatatsu Yamamoto, Shunji Shimaoka, Naofumi Mukaida, Yasuo Takeda, Katsushi Yamada, Tomoyoshi Soga, Tatsuhiko Furukawa, Shin-ichi Akiyama

Published Dec 1, 2014 · Vol. 5, No. 21 · pp. 10473-10485

Connexin32 regulates hepatoma cell metastasis and proliferation via the p53 and Akt pathways Research Paper

Bixing Zhao, Wenxiu Zhao, Yu Wang, Yaping Xu, Jianfeng Xu, Kai Tang, Sheng Zhang, Zhenyu Yin, Qiao Wu, Xiaomin Wang

Published Nov 27, 2014 · Vol. 6, No. 12 · pp. 10116-10133

EphrinB1: novel microtubule associated protein whose expression affects taxane sensitivity Research Paper

Paul L. Colbert, Daniel W. Vermeer, Bryant G. Wieking, John H. Lee, Paola D. Vermeer

Published Nov 26, 2014 · Vol. 6, No. 2 · pp. 953-968

Dichloroacetate, a selective mitochondria-targeting drug for oral squamous cell carcinoma: a metabolic perspective of treatment Research Paper

Vitalba Ruggieri, Francesca Agriesti, Rosella Scrima, Ilaria Laurenzana, Donatella Perrone, Tiziana Tataranni, Carmela Mazzoccoli, Lorenzo Lo Muzio, Nazzareno Capitanio, Claudia Piccoli

Published Nov 25, 2014 · Vol. 6, No. 2 · pp. 1217-1230

Keywords: oral squamous cell carcinoma, dichloroacetate, oxidative metabolism, mitochondria, reactive oxygen species

DNA methylome analysis identifies epigenetic silencing of FHIT as a determining factor for radiosensitivity in oral cancer: an outcome-predicting and treatment-implicating study Research Paper

Hon-Yi Lin, Shih-Kai Hung, Moon-Sing Lee, Wen-Yen Chiou, Tze-Ta Huang, Chih-En Tseng, Liang-Yu Shih, Ru-Inn Lin, Jora M.J. Lin, Yi-Hui Lai, Chia-Bin Chang, Feng-Chun Hsu, Liang-Cheng Chen, Shiang-Jiun Tsai, Yu-Chieh Su, Szu-Chi Li, Hung-Chih Lai, Wen-Lin Hsu, Dai-Wei Liu, Chien-Kuo Tai, Shu-Fen Wu, Michael W.Y. Chan

Published Nov 25, 2014 · Vol. 6, No. 2 · pp. 915-934

WMJ-S-001, a novel aliphatic hydroxamate derivative, exhibits anti-angiogenic activities via Src-homology-2-domain-containing protein tyrosine phosphatase 1 Research Paper

Yi-Fang Chang, Ya-Fen Hsu, Pei-Ting Chiu, Wei-Jan Huang, Shiu-Wen Huang, George Ou, Joen-Rong Sheu, Ming-Jen Hsu

Published Nov 16, 2014 · Vol. 6, No. 1 · pp. 85-100

Glycolysis is the primary bioenergetic pathway for cell motility and cytoskeletal remodeling in human prostate and breast cancer cells Research Paper

Takumi Shiraishi, James E. Verdone, Jessie Huang, Ulf D. Kahlert, James R. Hernandez, Gonzalo Torga, Jelani C. Zarif, Tamir Epstein, Robert Gatenby, Annemarie McCartney, Jennifer H. Elisseeff, Steven M. Mooney, Steven S. An, Kenneth J. Pienta

Published Nov 16, 2014 · Vol. 6, No. 1 · pp. 130-143

CD147 promotes Src-dependent activation of Rac1 signaling through STAT3/DOCK8 during the motility of hepatocellular carcinoma cells Research Paper

Shi-Jie Wang, Hong-Yong Cui, Yan-Mei Liu, Pu Zhao, Yang Zhang, Zhi-Guang Fu, Zhi-Nan Chen, Jian-Li Jiang

Published Nov 16, 2014 · Vol. 6, No. 1 · pp. 243-257

Reduced miR-126 expression facilitates angiogenesis of gastric cancer through its regulation on VEGF-A Research Paper

Hongxia Chen, Lingmin Li, Shaojun Wang, Yupeng Lei, Qi Ge, Nonghua Lv, Xiaodong Zhou, Changyan Chen

Published Nov 15, 2014 · Vol. 5, No. 23 · pp. 11873-11885

Keywords: miR-126, gastric cancer, angiogenesis, VEGF, Akt/m-TOR phosphorylation

DNA damage-induced S and G2/M cell cycle arrest requires mTORC2-dependent regulation of Chk1 Research Paper

Jogitha Selvarajah, Androulla Elia, Veronica A. Carroll, Abdeladim Moumen

Published Nov 15, 2014 · Vol. 6, No. 1 · pp. 427-440

LIGHT/TNFSF14 increases osteoclastogenesis and decreases osteoblastogenesis in multiple myeloma-bone disease Research Paper

Giacomina Brunetti, Rita Rizzi, Angela Oranger, Isabella Gigante, Giorgio Mori, Grazia Taurino, Teresa Mongelli, Graziana Colaianni, Adriana Di Benedetto, Roberto Tamma, Giuseppe Ingravallo, Anna Napoli, Maria Felicia Faienza, Anna Mestice, Paola Curci, Giorgina Specchia, Silvia Colucci, Maria Grano

Published Nov 12, 2014 · Vol. 5, No. 24 · pp. 12950-12967

Keywords: LIGHT/TNFSF14, Multiple Myeloma, Bone disease, Osteoclast, Osteoblast

Metformin and erlotinib synergize to inhibit basal breast cancer Research Paper

Ying-Ka Ingar Lau, Xing Du, Vinayak Rayannavar, Benjamin Hopkins, Jacquelyn Shaw, Eliana Bessler, Tiffany Thomas, Maira M. Pires, Megan Keniry, Ramon E. Parsons, Serge Cremers, Matthias Szabolcs, Matthew A. Maurer

Published Nov 4, 2014 · Vol. 5, No. 21 · pp. 10503-10517

Surgical procedures and postsurgical tissue processing significantly affect expression of genes and EGFR-pathway proteins in colorectal cancer tissue Priority Research Paper

Kerstin A. David, Florian T. Unger, Philipp Uhlig, Hartmut Juhl, Helen M. Moore, Carolyn Compton, BjÃ¶rn Nashan, Arnulf DÃ¶rner, Andreas de Weerth, Carsten Zornig

Published Nov 3, 2014 · Vol. 5, No. 22 · pp. 11017-11028

VER-246608, a novel pan-isoform ATP competitive inhibitor of pyruvate dehydrogenase kinase, disrupts Warburg metabolism and induces context-dependent cytostasis in cancer cells Research Paper

Jonathan D. Moore, Anna Staniszewska, Terence Shaw, Jalanie Dâ€™Alessandro, Ben Davis, Alan Surgenor, Lisa Baker, Natalia Matassova, James Murray, Alba Macias, Paul Brough, Mike Wood, Patrick C. Mahon

Published Nov 2, 2014 · Vol. 5, No. 24 · pp. 12862-12876

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PRK1/PKN1 controls migration and metastasis of androgen-independent prostate cancer cells Research Paper

Î³-H2AX promotes hepatocellular carcinoma angiogenesis via EGFR/HIF-1Î±/VEGF pathways under hypoxic condition Research Paper

Inhibition of HIF-1Î± by PX-478 enhances the anti-tumor effect of gemcitabine by inducing immunogenic cell death in pancreatic ductal adenocarcinoma Research Paper

The PI3K inhibitor GDC-0941 displays promising in vitro and in vivo efficacy for targeted medulloblastoma therapy Research Paper

The activity regulation of the mitotic centromere-associated kinesin by Polo-like kinase 1 Research Paper

Targeting of hyperactivated mTOR signaling in high-risk acute lymphoblastic leukemia in a pre-clinical model Priority Research Paper

Thymidine phosphorylase activates NFÎºB and stimulates the expression of angiogenic and metastatic factors in human cancer cells Research Paper

Connexin32 regulates hepatoma cell metastasis and proliferation via the p53 and Akt pathways Research Paper

EphrinB1: novel microtubule associated protein whose expression affects taxane sensitivity Research Paper

Dichloroacetate, a selective mitochondria-targeting drug for oral squamous cell carcinoma: a metabolic perspective of treatment Research Paper

DNA methylome analysis identifies epigenetic silencing of FHIT as a determining factor for radiosensitivity in oral cancer: an outcome-predicting and treatment-implicating study Research Paper

WMJ-S-001, a novel aliphatic hydroxamate derivative, exhibits anti-angiogenic activities via Src-homology-2-domain-containing protein tyrosine phosphatase 1 Research Paper

Glycolysis is the primary bioenergetic pathway for cell motility and cytoskeletal remodeling in human prostate and breast cancer cells Research Paper

CD147 promotes Src-dependent activation of Rac1 signaling through STAT3/DOCK8 during the motility of hepatocellular carcinoma cells Research Paper

Reduced miR-126 expression facilitates angiogenesis of gastric cancer through its regulation on VEGF-A Research Paper

DNA damage-induced S and G2/M cell cycle arrest requires mTORC2-dependent regulation of Chk1 Research Paper

LIGHT/TNFSF14 increases osteoclastogenesis and decreases osteoblastogenesis in multiple myeloma-bone disease Research Paper

Metformin and erlotinib synergize to inhibit basal breast cancer Research Paper

Surgical procedures and postsurgical tissue processing significantly affect expression of genes and EGFR-pathway proteins in colorectal cancer tissue Priority Research Paper

VER-246608, a novel pan-isoform ATP competitive inhibitor of pyruvate dehydrogenase kinase, disrupts Warburg metabolism and induces context-dependent cytostasis in cancer cells Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

PRK1/PKN1 controls migration and metastasis of androgen-independent prostate cancer cells Research Paper

Î³-H2AX promotes hepatocellular carcinoma angiogenesis via EGFR/HIF-1Î±/VEGF pathways under hypoxic condition Research Paper

Inhibition of HIF-1Î± by PX-478 enhances the anti-tumor effect of gemcitabine by inducing immunogenic cell death in pancreatic ductal adenocarcinoma Research Paper

The PI3K inhibitor GDC-0941 displays promising in vitro and in vivo efficacy for targeted medulloblastoma therapy Research Paper

The activity regulation of the mitotic centromere-associated kinesin by Polo-like kinase 1 Research Paper

Targeting of hyperactivated mTOR signaling in high-risk acute lymphoblastic leukemia in a pre-clinical model Priority Research Paper

Thymidine phosphorylase activates NFÎºB and stimulates the expression of angiogenic and metastatic factors in human cancer cells Research Paper

Connexin32 regulates hepatoma cell metastasis and proliferation via the p53 and Akt pathways Research Paper

EphrinB1: novel microtubule associated protein whose expression affects taxane sensitivity Research Paper

Dichloroacetate, a selective mitochondria-targeting drug for oral squamous cell carcinoma: a metabolic perspective of treatment Research Paper

DNA methylome analysis identifies epigenetic silencing of FHIT as a determining factor for radiosensitivity in oral cancer: an outcome-predicting and treatment-implicating study Research Paper

WMJ-S-001, a novel aliphatic hydroxamate derivative, exhibits anti-angiogenic activities via Src-homology-2-domain-containing protein tyrosine phosphatase 1 Research Paper

Glycolysis is the primary bioenergetic pathway for cell motility and cytoskeletal remodeling in human prostate and breast cancer cells Research Paper

CD147 promotes Src-dependent activation of Rac1 signaling through STAT3/DOCK8 during the motility of hepatocellular carcinoma cells Research Paper

Reduced miR-126 expression facilitates angiogenesis of gastric cancer through its regulation on VEGF-A Research Paper

DNA damage-induced S and G2/M cell cycle arrest requires mTORC2-dependent regulation of Chk1 Research Paper

LIGHT/TNFSF14 increases osteoclastogenesis and decreases osteoblastogenesis in multiple myeloma-bone disease Research Paper

Metformin and erlotinib synergize to inhibit basal breast cancer Research Paper

Surgical procedures and postsurgical tissue processing significantly affect expression of genes and EGFR-pathway proteins in colorectal cancer tissue Priority Research Paper

VER-246608, a novel pan-isoform ATP competitive inhibitor of pyruvate dehydrogenase kinase, disrupts Warburg metabolism and induces context-dependent cytostasis in cancer cells Research Paper