The Oncosearch | Oncotarget

Targeting cytosolic phospholipase A₂ Î± in colorectal cancer cells inhibits constitutively activated protein kinase B (AKT) and cell proliferation Research Paper

Zhong Zheng, Xiangyi He, Chanlu Xie, Sheng Hua, Jianfang Li, Tingfeng Wang, Mu Yao, Soma Vignarajan, Ying Teng, Leila Hejazi, Bingya Liu, Qihan Dong

Published Oct 28, 2014 · Vol. 5, No. 23 · pp. 12304-12316

Metformin impairs Rho GTPase signaling to induce apoptosis in neuroblastoma cells and inhibits growth of tumors in the xenograft mouse model of neuroblastoma Research Paper

Ambrish Kumar, Nadia Al-Sammarraie, Donald J. DiPette, Ugra S. Singh

Published Oct 21, 2014 · Vol. 5, No. 22 · pp. 11709-11722

The tyrosine phosphatase PTPRO sensitizes colon cancer cells to anti-EGFR therapy through activation of SRC-mediated EGFR signaling Research Paper

Layka Abbasi Asbagh, Iria Vazquez, Loredana Vecchione, Eva Budinska, Veerle De Vriendt, Maria Francesca Baietti, Mikhail Steklov, Bart Jacobs, Nicholas Hoe, Sharat Singh, Naga-Sailaja Imjeti, Pascale Zimmermann, Anna Sablina, Sabine Tejpar

Published Oct 11, 2014 · Vol. 5, No. 20 · pp. 10070-10083

CCL5 promotes VEGF-dependent angiogenesis by down-regulating miR-200b through PI3K/Akt signaling pathway in human chondrosarcoma cells Research Paper

Guan-Ting Liu, Hsien-Te Chen, Hsi-Kai Tsou, Tzu-Wei Tan, Yi-Chin Fong, Po-Chen Chen, Wei-Hung Yang, Shih-Wei Wang, Jui-Chieh Chen, Chih-Hsin Tang

Published Sep 26, 2014 · Vol. 5, No. 21 · pp. 10718-10731

Simultaneous targeting of PI3KÎ´ and a PI3KÎ´-dependent MEK1/2-Erk1/2 pathway for therapy in pediatric B-cell acute lymphoblastic leukemia Research Paper

Xiang Wang, Xi Zhang, Ben-shang Li, Xiaowen Zhai, Zhuo Yang, Li-xia Ding, Hongsheng Wang, Chris Liang, Weiliang Zhu, Jian Ding, Ling-hua Meng

Published Sep 26, 2014 · Vol. 5, No. 21 · pp. 10732-10744

Resveratrol potentiates the in vitro and in vivo anti-tumoral effects of curcumin in head and neck carcinomas Research Paper

Laura Masuelli, Enrica Di Stefano, Massimo Fantini, Rosanna Mattera, Monica Benvenuto, Laura Marzocchella, Pamela Sacchetti, Chiara Focaccetti, Roberta Bernardini, Ilaria Tresoldi, Valerio Izzi, Maurizio Mattei, Giovanni Vanni Frajese, Florigio Lista, Andrea Modesti, Roberto Bei

Published Sep 26, 2014 · Vol. 5, No. 21 · pp. 10745-10762

Androgen receptor promotes gastric cancer cell migration and invasion via AKT-phosphorylation dependent upregulation of matrix metalloproteinase 9 Research Paper

Bao-gui Zhang, Tao Du, Ming-de Zang, Qing Chang, Zhi-yuan Fan, Jian-fang Li, Bei-qin Yu, Li-ping Su, Chen Li, Chao Yan, Qin-long Gu, Zheng-gang Zhu, Min Yan, Bingya Liu

Published Sep 25, 2014 · Vol. 5, No. 21 · pp. 10584-10595

Pharmacological targeting the ATRâ€“CHK1â€“WEE1 axis involves balancing cell growth stimulation and apoptosis Research Paper

Joyce P.Y. Mak, Wing Yu Man, Hoi Tang Ma, Randy Y.C. Poon

Published Sep 25, 2014 · Vol. 5, No. 21 · pp. 10546-10557

Acidosis promotes invasiveness of breast cancer cells through ROS-AKT-NF-ÎºB pathway Research Paper

Subash C. Gupta, Ramesh Singh, Radhika Pochampally, Kounosuke Watabe, Yin-Yuan Mo

Published Sep 25, 2014 · Vol. 5, No. 23 · pp. 12070-12082

Src-dependent phosphorylation at Y406 on the thyroid hormone receptor Î² confers the tumor suppressor activity Research Paper

Jeong Won Park, Li Zhao, Paul Webb, Sheue-yann Cheng

Published Sep 16, 2014 · Vol. 5, No. 20 · pp. 10002-10016

Ibrutinib inhibits SDF1/CXCR4 mediated migration in AML Research Paper

Lyubov Zaitseva, Megan Y. Murray, Manar S. Shafat, Matthew J. Lawes, David J. MacEwan, Kristian M. Bowles, Stuart A. Rushworth

Published Sep 16, 2014 · Vol. 5, No. 20 · pp. 9930-9938

Silibinin inhibits aberrant lipid metabolism, proliferation and emergence of androgen-independence in prostate cancer cells via primarily targeting the sterol response element binding protein 1 Research Paper

Dhanya K. Nambiar, Gagan Deep, Rana P. Singh, Chapla Agarwal, Rajesh Agarwal

Published Sep 16, 2014 · Vol. 5, No. 20 · pp. 10017-10033

CUSP9* treatment protocol for recurrent glioblastoma: aprepitant, artesunate, auranofin, captopril, celecoxib, disulfiram, itraconazole, ritonavir, sertraline augmenting continuous low dose temozolomide Research Perspective

Richard E. Kast, Georg Karpel-Massler, Marc-Eric Halatsch

Published Aug 29, 2014 · Vol. 5, No. 18 · pp. 8052-8082

Vav1 promotes lung cancer growth by instigating tumor-microenvironment cross-talk via growth factor secretion Research Paper

Shulamit Sebban, Marganit Farago, Shiran Rabinovich, Galit Lazer, Yulia Idelchuck, Lena Ilan, Eli Pikarsky, Shulamit Katzav

Published Aug 27, 2014 · Vol. 5, No. 19 · pp. 9214-9226

Cancer-derived immunoglobulin G promotes LPS-induced proinflammatory cytokine production via binding to TLR4 in cervical cancer cells Research Paper

Juping Wang, Danyi Lin, Hui Peng, Jimin Shao, Jiang Gu

Published Aug 23, 2014 · Vol. 5, No. 20 · pp. 9727-9743

Keywords: IgG, cancer, promote, TLR4, proinflammatory cytokine

Prolactin induces up-regulation of its cognate receptor in breast cancer cells via transcriptional activation of its generic promoter by cross-talk between ERÎ± and STAT5 Research Paper

Raghuveer Kavarthapu, Chon-Hwa Tsai Morris, Maria L. Dufau

Published Aug 21, 2014 · Vol. 5, No. 19 · pp. 9079-9091

Multiple blocks in the engagement of oxidative phosphorylation in putative ovarian cancer stem cells: implication for maintenance therapy with glycolysis inhibitors Research Paper

Ayesha B. Alvero, Michele K. Montagna, Natalia J. Sumi, Won Duk Joo, Emma Graham, Gil Mor

Published Aug 19, 2014 · Vol. 5, No. 18 · pp. 8703-8715

Intracellular and extracellular domains of protein tyrosine phosphatase PTPRZ-B differentially regulate glioma cell growth and motility Research Paper

Annika M. Bourgonje, Anna C. Navis, Jan T.G. Schepens, Kiek Verrijp, Liesbeth Hovestad, Riet Hilhorst, Sheila Harroch, Pieter Wesseling, William P.J. Leenders, Wiljan J.A.J. Hendriks

Published Aug 19, 2014 · Vol. 5, No. 18 · pp. 8690-8702

Molecular rationale for the use of PI3K/AKT/mTOR pathway inhibitors in combination with crizotinib in ALK-mutated neuroblastoma Research Paper

Nathan F. Moore, Anna M. Azarova, Namrata Bhatnagar, Kenneth N. Ross, Lauren E. Drake, Stacey Frumm, Qinsong S. Liu, Amanda L. Christie, Takaomi Sanda, Louis Chesler, Andrew L. Kung, Nathanael S. Gray, Kimberly Stegmaier, Rani E. George

Published Aug 19, 2014 · Vol. 5, No. 18 · pp. 8737-8749

Catalytic mTOR inhibitors can overcome intrinsic and acquired resistance to allosteric mTOR inhibitors Research Paper

Burhan Hassan, Argun Akcakanat, Takafumi Sangai, Kurt W. Evans, Farrell Adkins, Agda Karina Eterovic, Hao Zhao, Ken Chen, Huiqin Chen, Kim-Anh Do, Shelly M. Xie, Ashley M. Holder, Aung Naing, Gordon B. Mills, Funda Meric-Bernstam

Published Aug 10, 2014 · Vol. 5, No. 18 · pp. 8544-8557

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Targeting cytosolic phospholipase A₂ Î± in colorectal cancer cells inhibits constitutively activated protein kinase B (AKT) and cell proliferation Research Paper

Metformin impairs Rho GTPase signaling to induce apoptosis in neuroblastoma cells and inhibits growth of tumors in the xenograft mouse model of neuroblastoma Research Paper

The tyrosine phosphatase PTPRO sensitizes colon cancer cells to anti-EGFR therapy through activation of SRC-mediated EGFR signaling Research Paper

CCL5 promotes VEGF-dependent angiogenesis by down-regulating miR-200b through PI3K/Akt signaling pathway in human chondrosarcoma cells Research Paper

Simultaneous targeting of PI3KÎ´ and a PI3KÎ´-dependent MEK1/2-Erk1/2 pathway for therapy in pediatric B-cell acute lymphoblastic leukemia Research Paper

Resveratrol potentiates the in vitro and in vivo anti-tumoral effects of curcumin in head and neck carcinomas Research Paper

Androgen receptor promotes gastric cancer cell migration and invasion via AKT-phosphorylation dependent upregulation of matrix metalloproteinase 9 Research Paper

Pharmacological targeting the ATRâ€“CHK1â€“WEE1 axis involves balancing cell growth stimulation and apoptosis Research Paper

Acidosis promotes invasiveness of breast cancer cells through ROS-AKT-NF-ÎºB pathway Research Paper

Src-dependent phosphorylation at Y406 on the thyroid hormone receptor Î² confers the tumor suppressor activity Research Paper

Ibrutinib inhibits SDF1/CXCR4 mediated migration in AML Research Paper

Silibinin inhibits aberrant lipid metabolism, proliferation and emergence of androgen-independence in prostate cancer cells via primarily targeting the sterol response element binding protein 1 Research Paper

CUSP9* treatment protocol for recurrent glioblastoma: aprepitant, artesunate, auranofin, captopril, celecoxib, disulfiram, itraconazole, ritonavir, sertraline augmenting continuous low dose temozolomide Research Perspective

Vav1 promotes lung cancer growth by instigating tumor-microenvironment cross-talk via growth factor secretion Research Paper

Cancer-derived immunoglobulin G promotes LPS-induced proinflammatory cytokine production via binding to TLR4 in cervical cancer cells Research Paper

Prolactin induces up-regulation of its cognate receptor in breast cancer cells via transcriptional activation of its generic promoter by cross-talk between ERÎ± and STAT5 Research Paper

Multiple blocks in the engagement of oxidative phosphorylation in putative ovarian cancer stem cells: implication for maintenance therapy with glycolysis inhibitors Research Paper

Intracellular and extracellular domains of protein tyrosine phosphatase PTPRZ-B differentially regulate glioma cell growth and motility Research Paper

Molecular rationale for the use of PI3K/AKT/mTOR pathway inhibitors in combination with crizotinib in ALK-mutated neuroblastoma Research Paper

Catalytic mTOR inhibitors can overcome intrinsic and acquired resistance to allosteric mTOR inhibitors Research Paper

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European Cancer and Oncology Congress

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Targeting cytosolic phospholipase A2 Î± in colorectal cancer cells inhibits constitutively activated protein kinase B (AKT) and cell proliferation Research Paper

Metformin impairs Rho GTPase signaling to induce apoptosis in neuroblastoma cells and inhibits growth of tumors in the xenograft mouse model of neuroblastoma Research Paper

The tyrosine phosphatase PTPRO sensitizes colon cancer cells to anti-EGFR therapy through activation of SRC-mediated EGFR signaling Research Paper

CCL5 promotes VEGF-dependent angiogenesis by down-regulating miR-200b through PI3K/Akt signaling pathway in human chondrosarcoma cells Research Paper

Simultaneous targeting of PI3KÎ´ and a PI3KÎ´-dependent MEK1/2-Erk1/2 pathway for therapy in pediatric B-cell acute lymphoblastic leukemia Research Paper

Resveratrol potentiates the in vitro and in vivo anti-tumoral effects of curcumin in head and neck carcinomas Research Paper

Androgen receptor promotes gastric cancer cell migration and invasion via AKT-phosphorylation dependent upregulation of matrix metalloproteinase 9 Research Paper

Pharmacological targeting the ATRâ€“CHK1â€“WEE1 axis involves balancing cell growth stimulation and apoptosis Research Paper

Acidosis promotes invasiveness of breast cancer cells through ROS-AKT-NF-ÎºB pathway Research Paper

Src-dependent phosphorylation at Y406 on the thyroid hormone receptor Î² confers the tumor suppressor activity Research Paper

Ibrutinib inhibits SDF1/CXCR4 mediated migration in AML Research Paper

Silibinin inhibits aberrant lipid metabolism, proliferation and emergence of androgen-independence in prostate cancer cells via primarily targeting the sterol response element binding protein 1 Research Paper

CUSP9* treatment protocol for recurrent glioblastoma: aprepitant, artesunate, auranofin, captopril, celecoxib, disulfiram, itraconazole, ritonavir, sertraline augmenting continuous low dose temozolomide Research Perspective

Vav1 promotes lung cancer growth by instigating tumor-microenvironment cross-talk via growth factor secretion Research Paper

Cancer-derived immunoglobulin G promotes LPS-induced proinflammatory cytokine production via binding to TLR4 in cervical cancer cells Research Paper

Prolactin induces up-regulation of its cognate receptor in breast cancer cells via transcriptional activation of its generic promoter by cross-talk between ERÎ± and STAT5 Research Paper

Multiple blocks in the engagement of oxidative phosphorylation in putative ovarian cancer stem cells: implication for maintenance therapy with glycolysis inhibitors Research Paper

Intracellular and extracellular domains of protein tyrosine phosphatase PTPRZ-B differentially regulate glioma cell growth and motility Research Paper

Molecular rationale for the use of PI3K/AKT/mTOR pathway inhibitors in combination with crizotinib in ALK-mutated neuroblastoma Research Paper

Catalytic mTOR inhibitors can overcome intrinsic and acquired resistance to allosteric mTOR inhibitors Research Paper

Targeting cytosolic phospholipase A₂ Î± in colorectal cancer cells inhibits constitutively activated protein kinase B (AKT) and cell proliferation Research Paper