The Oncosearch | Oncotarget

Multi-omic based molecular profiling of advanced cancer identifies treatable targets and improves survival in individual patients Research Paper

Alexandra Samsen, Silvia von der Heyde, Carsten Bokemeyer, Kerstin A. David, Bernd Flath, Max Graap, Bianca Grebenstein, Ludger Heflik, Wiebke Hollburg, Peter Layer, Eike von Leitner, Friedrich Overkamp, Wolfgang Saeger, Sandra Schneider, Cay-Uwe von Seydewitz, Axel Stang, Alexander Stein, Carsten Zornig, Hartmut Juhl

Published Oct 5, 2018 · Vol. 9, No. 78 · pp. 34794-34809

XPO1 inhibition by selinexor induces potent cytotoxicity against high grade bladder malignancies Research Paper

Han Bit Baek, Alan P. Lombard, Stephen J. Libertini, Aleida Fernandez-Rubio, Ruth Vinall, Regina Gandour-Edwards, Rachel Nakagawa, Kathleen Vidallo, Kristine Nishida, Salma Siddiqui, Hiromi Wettersten, Yosef Landesman, Robert H. Weiss, Paramita M. Ghosh, Maria Mudryj

Published Oct 2, 2018 · Vol. 9, No. 77 · pp. 34567-34581

The ratio of STAT1 to STAT3 expression is a determinant of colorectal cancer growth Research Paper

Harini Nivarthi, Claire Gordziel, Madeleine Themanns, Nina Kramer, Markus Eberl, BjÃ¶rn Rabe, Michaela Schlederer, Stefan Rose-John, Thomas KnÃ¶sel, Lukas Kenner, Patricia Freund, Fritz Aberger, Xiaonan Han, Robert Kralovics, Helmut Dolznig, Susanne Jennek, Karlheinz Friedrich, Richard Moriggl

Published Sep 18, 2018 · Vol. 7, No. 32 · pp. 51096-51106

STAT3 is constitutively acetylated on lysine 685 residues in chronic lymphocytic leukemia cells Research Paper

Uri Rozovski, David M. Harris, Ping Li, Zhiming Liu, Preetesh Jain, Alessandra Ferrajoli, Jan Burger, Phillip Thompson, Nitin Jain, William Wierda, Michael J. Keating, Zeev Estrov

Published Sep 14, 2018 · Vol. 9, No. 72 · pp. 33710-33718

Elucidating the novel BRCA1 function as a non-genomic metabolic restraint in ER-positive breast cancer cell lines Research Paper

Moses Koobotse, Jeff Holly, Claire Perks

Published Sep 11, 2018 · Vol. 9, No. 71 · pp. 33562-33576

Trisenox disrupts MDM2-DAXX-HAUSP complex and activates p53, cell cycle regulation and apoptosis in acute leukemia cells Research Paper

Sanjay Kumar, Andrea Brown, Paul B. Tchounwou

Published Sep 4, 2018 · Vol. 9, No. 69 · pp. 33138-33148

Combination of ATO with FLT3 TKIs eliminates FLT3/ITD+ leukemia cells through reduced expression of FLT3 Priority Research Paper

Kozo Nagai, Lihong Hou, Li Li, Bao Nguyen, Tessa Seale, Courtney Shirley, Hayley Ma, Mark Levis, Gabriel Ghiaur, Amy Duffield, Donald Small

Published Aug 31, 2018 · Vol. 9, No. 68 · pp. 32885-32899

Combination of resveratrol and 5-flurouracil enhanced anti-telomerase activity and apoptosis by inhibiting STAT3 and Akt signaling pathways in human colorectal cancer cells Research Paper

Seyung S. Chung, Pranabananda Dutta, David Austin, Piwen Wang, Adam Awad, Jaydutt V. Vadgama

Published Aug 31, 2018 · Vol. 9, No. 68 · pp. 32943-32957

Integrin α2β1 decelerates proliferation, but promotes survival and invasion of prostate cancer cells Research Paper

Marjaana Ojalill, Marjaana Parikainen, Pekka Rappu, Elina Aalto, Johanna Jokinen, Noora Virtanen, Elina SiljamÃ¤ki, Jyrki Heino

Published Aug 21, 2018 · Vol. 9, No. 65 · pp. 32435-32447

Zac1 regulates IL-11 expression in osteoarthritis Research Paper

Chun-Lin Kuo, Shu-Ting Liu, Yung-Lung Chang, Chia-Chun Wu, Shih-Ming Huang

Published Aug 21, 2018 · Vol. 9, No. 65 · pp. 32478-32495

Therapeutic targeting of Aurora A kinase in Philadelphia chromosome-positive ABL tyrosine kinase inhibitor-resistant cells Research Paper

Seiichi Okabe, Tetsuzo Tauchi, Yuko Tanaka, Kazuma Ohyashiki

Published Aug 21, 2018 · Vol. 9, No. 65 · pp. 32496-32506

Ponatinib exerts anti-angiogenic effects in the zebrafish and human umbilical vein endothelial cells via blocking VEGFR signaling pathway Research Paper

Nana Ai, Cheong-Meng Chong, Weiting Chen, Zhe Hu, Huanxing Su, Guokai Chen, Queenie Wing Lei Wong, Wei Ge

Published Aug 10, 2018 · Vol. 9, No. 62 · pp. 31958-31970

Development of novel SUV39H2 inhibitors that exhibit growth suppressive effects in mouse xenograft models and regulate the phosphorylation of H2AX Research Paper

Theodore Vougiouklakis, Vassiliki Saloura, Jae-Hyun Park, Naofumi Takamatsu, Takashi Miyamoto, Yusuke Nakamura, Yo Matsuo

Published Aug 7, 2018 · Vol. 9, No. 61 · pp. 31820-31831

Interaction between N-cadherin and decoy receptor-2 regulates apoptosis in head and neck cancer Research Paper

Phuong Thao Nguyen, Dung Nguyen, Chanbora Chea, Mutsumi Miyauchi, Makiko Fujii, Takashi Takata

Published Jul 31, 2018 · Vol. 9, No. 59 · pp. 31516-31530

The E3 ubiquitin ligase HERC1 controls the ERK signaling pathway targeting C-RAF for degradation Research Paper

Taiane Schneider, Arturo Martinez-Martinez, Monica Cubillos-Rojas, Ramon Bartrons, Francesc Ventura, Jose Luis Rosa

Published Jul 31, 2018 · Vol. 9, No. 59 · pp. 31531-31548

Periostin is a negative prognostic factor and promotes cancer cell proliferation in non-small cell lung cancer Research Paper

Toshimasa Okazaki, Keiichi Tamai, Rie Shibuya, Mao Nakamura, Mai Mochizuki, Kazunori Yamaguchi, Jiro Abe, Satomi Takahashi, Ikuro Sato, Akira Kudo, Yoshinori Okada, Kennichi Satoh

Published Jul 27, 2018 · Vol. 9, No. 58 · pp. 31187-31199

STAT3 is constitutively activated in chronic active Epstein-Barr virus infection and can be a therapeutic target Research Paper

Erika Onozawa, Haruna Shibayama, Honami Takada, Ken-Ichi Imadome, Sho Aoki, Mayumi Yoshimori, Norio Shimizu, Shigeyoshi Fujiwara, Takatoshi Koyama, Osamu Miura, Ayako Arai

Published Jul 24, 2018 · Vol. 9, No. 57 · pp. 31077-31089

Chk1 inhibition as a novel therapeutic strategy in melanoma Research Paper

Bor-Jang Hwang, Gautam Adhikary, Richard L. Eckert, A-Lien Lu

Published Jul 13, 2018 · Vol. 9, No. 54 · pp. 30450-30464

Phosphatidylinositol 3-kinase p110Î´ expression in Merkel cell carcinoma Research Paper

Emil Chteinberg, Dorit Rennspiess, Ryan Sambo, Samantha Tauchmann, Nicole W.J. Kelleners-Smeets, VÃ©ronique Winnepenninckx, Ernst-Jan Speel, Anna Kordelia Kurz, Martin Zenke, Axel zur Hausen

Published Jul 3, 2018 · Vol. 9, No. 51 · pp. 29565-29573

A single amino acid substitution in CXCL12 confers functional selectivity at the beta-arrestin level Research Paper

Antonella Rigo, Isacco Ferrarini, Giulio Innamorati, Fabrizio Vinante

Published Jun 22, 2018 · Vol. 9, No. 48 · pp. 28830-28841

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Multi-omic based molecular profiling of advanced cancer identifies treatable targets and improves survival in individual patients Research Paper

XPO1 inhibition by selinexor induces potent cytotoxicity against high grade bladder malignancies Research Paper

The ratio of STAT1 to STAT3 expression is a determinant of colorectal cancer growth Research Paper

STAT3 is constitutively acetylated on lysine 685 residues in chronic lymphocytic leukemia cells Research Paper

Elucidating the novel BRCA1 function as a non-genomic metabolic restraint in ER-positive breast cancer cell lines Research Paper

Trisenox disrupts MDM2-DAXX-HAUSP complex and activates p53, cell cycle regulation and apoptosis in acute leukemia cells Research Paper

Combination of ATO with FLT3 TKIs eliminates FLT3/ITD+ leukemia cells through reduced expression of FLT3 Priority Research Paper

Combination of resveratrol and 5-flurouracil enhanced anti-telomerase activity and apoptosis by inhibiting STAT3 and Akt signaling pathways in human colorectal cancer cells Research Paper

Integrin α2β1 decelerates proliferation, but promotes survival and invasion of prostate cancer cells Research Paper

Zac1 regulates IL-11 expression in osteoarthritis Research Paper

Therapeutic targeting of Aurora A kinase in Philadelphia chromosome-positive ABL tyrosine kinase inhibitor-resistant cells Research Paper

Ponatinib exerts anti-angiogenic effects in the zebrafish and human umbilical vein endothelial cells via blocking VEGFR signaling pathway Research Paper

Development of novel SUV39H2 inhibitors that exhibit growth suppressive effects in mouse xenograft models and regulate the phosphorylation of H2AX Research Paper

Interaction between N-cadherin and decoy receptor-2 regulates apoptosis in head and neck cancer Research Paper

The E3 ubiquitin ligase HERC1 controls the ERK signaling pathway targeting C-RAF for degradation Research Paper

Periostin is a negative prognostic factor and promotes cancer cell proliferation in non-small cell lung cancer Research Paper

STAT3 is constitutively activated in chronic active Epstein-Barr virus infection and can be a therapeutic target Research Paper

Chk1 inhibition as a novel therapeutic strategy in melanoma Research Paper

Phosphatidylinositol 3-kinase p110Î´ expression in Merkel cell carcinoma Research Paper

A single amino acid substitution in CXCL12 confers functional selectivity at the beta-arrestin level Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Multi-omic based molecular profiling of advanced cancer identifies treatable targets and improves survival in individual patients Research Paper

XPO1 inhibition by selinexor induces potent cytotoxicity against high grade bladder malignancies Research Paper

The ratio of STAT1 to STAT3 expression is a determinant of colorectal cancer growth Research Paper

STAT3 is constitutively acetylated on lysine 685 residues in chronic lymphocytic leukemia cells Research Paper

Elucidating the novel BRCA1 function as a non-genomic metabolic restraint in ER-positive breast cancer cell lines Research Paper

Trisenox disrupts MDM2-DAXX-HAUSP complex and activates p53, cell cycle regulation and apoptosis in acute leukemia cells Research Paper

Combination of ATO with FLT3 TKIs eliminates FLT3/ITD+ leukemia cells through reduced expression of FLT3 Priority Research Paper

Combination of resveratrol and 5-flurouracil enhanced anti-telomerase activity and apoptosis by inhibiting STAT3 and Akt signaling pathways in human colorectal cancer cells Research Paper

Integrin α2β1 decelerates proliferation, but promotes survival and invasion of prostate cancer cells Research Paper

Zac1 regulates IL-11 expression in osteoarthritis Research Paper

Therapeutic targeting of Aurora A kinase in Philadelphia chromosome-positive ABL tyrosine kinase inhibitor-resistant cells Research Paper

Ponatinib exerts anti-angiogenic effects in the zebrafish and human umbilical vein endothelial cells via blocking VEGFR signaling pathway Research Paper

Development of novel SUV39H2 inhibitors that exhibit growth suppressive effects in mouse xenograft models and regulate the phosphorylation of H2AX Research Paper

Interaction between N-cadherin and decoy receptor-2 regulates apoptosis in head and neck cancer Research Paper

The E3 ubiquitin ligase HERC1 controls the ERK signaling pathway targeting C-RAF for degradation Research Paper

Periostin is a negative prognostic factor and promotes cancer cell proliferation in non-small cell lung cancer Research Paper

STAT3 is constitutively activated in chronic active Epstein-Barr virus infection and can be a therapeutic target Research Paper

Chk1 inhibition as a novel therapeutic strategy in melanoma Research Paper

Phosphatidylinositol 3-kinase p110Î´ expression in Merkel cell carcinoma Research Paper

A single amino acid substitution in CXCL12 confers functional selectivity at the beta-arrestin level Research Paper