The Oncosearch | Oncotarget

Impact of eIF4E phosphorylation at Ser209 via MNK2a on tumour recurrence after curative surgery in localized clear cell renal cell carcinoma Research Paper

Osamu Ichiyanagi, Hiromi Ito, Sei Naito, Takanobu Kabasawa, Hidenori Kanno, Takafumi Narisawa, Masaki Ushijima, Yuta Kurota, Michinobu Ozawa, Toshihiko Sakurai, Hayato Nishida, Tomoyuki Kato, Mitsunori Yamakawa, Norihiko Tsuchiya

Published Jun 18, 2019 · Vol. 10, No. 40 · pp. 4053-4068

Keywords: renal cell carcinoma, phospho-eIF4E (p-eIF4E), MNK (MAPK-interacting kinase), recurrence-free, epithelial−mesenchymal transition

ETHE1 overexpression promotes SIRT1 and PGC1α mediated aerobic glycolysis, oxidative phosphorylation, mitochondrial biogenesis and colorectal cancer Research Paper

Mavee Witherspoon, Davinder Sandu, Changyuan Lu, Kehui Wang, Robert Edwards, Anthony Yeung, Ozkan Gelincik, Giovanni Manfredi, Steven Gross, Levy Kopelovich, Steven Lipkin

Published Jun 18, 2019 · Vol. 10, No. 40 · pp. 4004-4017

Keywords: familial adenomatous polyposis, ethylmalonic encephalopathy 1, mitochondrial bioenergetics, aerobic glycolysis, colorectal cancer

Correction: Glucocorticoid impairs cell-cell communication by autophagy-mediated degradation of connexin 43 in osteocytes Correction

Junjie Gao, Tak Sum Cheng, An Qin, Nathan J. Pavlos, Tao Wang, Kai Song, Yan Wang, Lianzhi Chen, Lin Zhou, Qing Jiang, Hiroshi Takayanagi, Sheng Yan, Minghao Zheng

Published Jun 12, 2019 · Vol. 10, No. 40 · pp. 4079-4079

Dicer prevents genome instability in response to replication stress Research Paper

Michalis Fragkos, Viviana Barra, Tom Egger, Benoit Bordignon, Delphine Lemacon, Valeria Naim, Arnaud Coquelle

Published Jun 11, 2019

Keywords: replication stress, common fragile sites, Dicer, genomic instability

Dicer prevents genome instability in response to replication stress Research Paper

Michalis Fragkos, Viviana Barra, Tom Egger, Benoit Bordignon, Delphine Lemacon, Valeria Naim, Arnaud Coquelle

Published Jun 11, 2019

Keywords: replication stress, common fragile sites, Dicer, genomic instability

1,4-dihydroxy quininib attenuates growth of colorectal cancer cells and xenografts and regulates the TIE-2 signaling pathway in patient tumours Research Paper

Clare T. Butler, Susan A. Kennedy, Amy Buckley, Ronan Doyle, Emer Conroy, William M. Gallagher, Jacintha O’Sullivan, Breandán N. Kennedy

Published Jun 4, 2019 · Vol. 10, No. 38 · pp. 3725-3744

Keywords: colorectal cancer, angiogenesis, cysteinyl leukotriene, drug discovery, xenograft

Synergistic inhibition of tumor cell proliferation by metformin and mito-metformin in the presence of iron chelators Research Paper

Gang Cheng, Jacek Zielonka, Micael Hardy, Olivier Ouari, Christopher R. Chitambar, Michael B. Dwinell, Balaraman Kalyanaraman

Published May 28, 2019 · Vol. 10, No. 37 · pp. 3518-3532

Keywords: iron chelators, mitochondria-targeting agents, cancer cell proliferation, biguanide; metformin analogs

Host targeted antiviral (HTA): functional inhibitor compounds of scaffold protein RACK1 inhibit herpes simplex virus proliferation Research Paper

Hemayet Ullah, Wangheng Hou, Sivanesan Dakshanamurthy, Qiyi Tang

Published May 14, 2019 · Vol. 10, No. 35 · pp. 3209-3226

Keywords: host targeted antiviral (HTA), herpes simplex virus (HSV), receptor for activated C kinase 1 (RACK1), RACK1 inhibitor, internal ribosomal entry site (IRES)

Constitutive activation of EGFR is associated with tumor progression and plays a prominent role in malignant phenotype of chondrosarcoma Research Paper

Jun Qin, Irfan Shaukat, Didier Mainard, Patrick Netter, Lydia Barré, Mohamed Ouzzine

Published May 7, 2019 · Vol. 10, No. 34 · pp. 3166-3182

Keywords: chondrosarcoma, EGF/EGFR signaling, biomarker, tyrosine kinase inhibitor, cell death

Thyroid hormones induce doxorubicin chemosensitivity through enzymes involved in chemotherapy metabolism in lymphoma T cells Research Paper

María Celeste Díaz Flaqué, Maria Florencia Cayrol, Helena Andrea Sterle, María del Rosario Aschero, Johanna Abigail Díaz Albuja, Blanca Isse, Ricardo Norberto Farías, Leandro Cerchietti, Cinthia Rosemblit, Graciela Alicia Cremaschi

Published Apr 30, 2019 · Vol. 10, No. 32 · pp. 3051-3065

Keywords: thyroid hormones, CYP 450, integrin αvβ3, doxorubicin, T-cell lymphoma

The glutamate release inhibitor riluzole increases DNA damage and enhances cytotoxicity in human glioma cells, in vitro and in vivo Research Paper

Atif J. Khan, Stephanie LaCava, Monal Mehta, Devora Schiff, Aditya Thandoni, Sachin Jhawar, Shabbar Danish, Bruce G. Haffty, Suzie Chen

Published Apr 19, 2019 · Vol. 10, No. 29 · pp. 2824-2834

Keywords: glutamate, glioma, riluzole, radiation therapy

PIM kinase inhibitor, AZD1208, inhibits protein translation and induces autophagy in primary chronic lymphocytic leukemia cells Research Paper

Fabiola Cervantes-Gomez, Christine M. Stellrecht, Mary L. Ayres, Michael J. Keating, William G. Wierda, Varsha Gandhi

Published Apr 19, 2019 · Vol. 10, No. 29 · pp. 2793-2809

Keywords: PIM kinase, chronic lymphocytic leukemia, protein translation, apoptosis, autophagy

Characterization of cancer-associated IDH2 mutations that differ in tumorigenicity, chemosensitivity and 2-hydroxyglutarate production Research Paper

Kevin P. Kotredes, Roshanak Razmpour, Evan Lutton, Mercedes Alfonso-Prieto, Servio H. Ramirez, Ana M. Gamero

Published Apr 12, 2019 · Vol. 10, No. 28 · pp. 2675-2692

Keywords: glioblastoma, IDH2, tumorigenesis, chemotherapy, biomarker

A state of stochastic cancer stemness through the CDK1-SOX2 axis Research Perspective

Dinoop Ravindran Menon, Mayumi Fujita

Published Apr 5, 2019 · Vol. 10, No. 27 · pp. 2583-2585

A novel anti-melanoma SRC-family kinase inhibitor Research Paper

Ruth Halaban, Antonella Bacchiocchi, Robert Straub, Jian Cao, Mario Sznol, Deepak Narayan, Ahmed Allam, Michael Krauthammer, Tarek S. Mansour

Published Mar 19, 2019 · Vol. 10, No. 23 · pp. 2237-2251

Keywords: melanoma, SRC-family kinase inhibitors, MAPK, MITF

HIGH expression of OSM and IL-6 are associated with decreased breast cancer survival: synergistic induction of IL-6 secretion by OSM and IL-1β Research Paper

Ken Tawara, Hannah Scott, Jacqueline Emathinger, Cody Wolf, Dollie LaJoie, Danielle Hedeen, Laura Bond, Paul Montgomery, Cheryl Jorcyk

Published Mar 12, 2019 · Vol. 10, No. 21 · pp. 2068-2085

Keywords: oncostatin M, interleukin-6 and oncostatin M, interleukin-1β, breast cancer, metastasis

AXL knockdown gene signature reveals a drug repurposing opportunity for a class of antipsychotics to reduce growth and metastasis of triple negative breast cancer Research Paper

Marie-Anne Goyette, Rebecca Cusseddu, Islam Elkholi, Afnan Abu-Thuraia, Nehme El-Hachem, Benjamin Haibe-Kains, Jean-Philippe Gratton, Jean-François Côté

Published Mar 12, 2019 · Vol. 10, No. 21 · pp. 2055-2067

Keywords: triple-negative breast cancer, drug repurposing, AXL, phenothiazines, metastasis

Rigosertib ameliorates the effects of oncogenic KRAS signaling in a murine model of myeloproliferative neoplasia Research Paper

Stacey J. Baker, Stephen C. Cosenza, M.V. Ramana Reddy, E. Premkumar Reddy

Published Mar 8, 2019 · Vol. 10, No. 20 · pp. 1932-1942

Phospho-ERK levels as predictors for chemotherapy of rectal carcinoma Research Paper

Susanne Holck, Louise Laurberg Klarskov, Lars-Inge Larsson

Published Mar 1, 2019 · Vol. 10, No. 18 · pp. 1745-1755

Statins affect human glioblastoma and other cancers through TGF-β inhibition Research Paper

Aizhen Xiao, Breanna Brenneman, Desiree Floyd, Laurey Comeau, Kelsey Spurio, Inan Olmez, Jeongwu Lee, Ichiro Nakano, Jakub Godlewski, Agnieszka Bronisz, Noritaka Kagaya, Kazuo Shin-ya, Benjamin Purow

Published Mar 1, 2019 · Vol. 10, No. 18 · pp. 1716-1728

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

Impact of eIF4E phosphorylation at Ser209 via MNK2a on tumour recurrence after curative surgery in localized clear cell renal cell carcinoma Research Paper

ETHE1 overexpression promotes SIRT1 and PGC1α mediated aerobic glycolysis, oxidative phosphorylation, mitochondrial biogenesis and colorectal cancer Research Paper

Correction: Glucocorticoid impairs cell-cell communication by autophagy-mediated degradation of connexin 43 in osteocytes Correction

Dicer prevents genome instability in response to replication stress Research Paper

Dicer prevents genome instability in response to replication stress Research Paper

1,4-dihydroxy quininib attenuates growth of colorectal cancer cells and xenografts and regulates the TIE-2 signaling pathway in patient tumours Research Paper

Synergistic inhibition of tumor cell proliferation by metformin and mito-metformin in the presence of iron chelators Research Paper

Host targeted antiviral (HTA): functional inhibitor compounds of scaffold protein RACK1 inhibit herpes simplex virus proliferation Research Paper

Constitutive activation of EGFR is associated with tumor progression and plays a prominent role in malignant phenotype of chondrosarcoma Research Paper

Thyroid hormones induce doxorubicin chemosensitivity through enzymes involved in chemotherapy metabolism in lymphoma T cells Research Paper

The glutamate release inhibitor riluzole increases DNA damage and enhances cytotoxicity in human glioma cells, in vitro and in vivo Research Paper

PIM kinase inhibitor, AZD1208, inhibits protein translation and induces autophagy in primary chronic lymphocytic leukemia cells Research Paper

Characterization of cancer-associated IDH2 mutations that differ in tumorigenicity, chemosensitivity and 2-hydroxyglutarate production Research Paper

A state of stochastic cancer stemness through the CDK1-SOX2 axis Research Perspective

A novel anti-melanoma SRC-family kinase inhibitor Research Paper

HIGH expression of OSM and IL-6 are associated with decreased breast cancer survival: synergistic induction of IL-6 secretion by OSM and IL-1β Research Paper

AXL knockdown gene signature reveals a drug repurposing opportunity for a class of antipsychotics to reduce growth and metastasis of triple negative breast cancer Research Paper

Rigosertib ameliorates the effects of oncogenic KRAS signaling in a murine model of myeloproliferative neoplasia Research Paper

Phospho-ERK levels as predictors for chemotherapy of rectal carcinoma Research Paper

Statins affect human glioblastoma and other cancers through TGF-β inhibition Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Impact of eIF4E phosphorylation at Ser209 via MNK2a on tumour recurrence after curative surgery in localized clear cell renal cell carcinoma Research Paper

ETHE1 overexpression promotes SIRT1 and PGC1α mediated aerobic glycolysis, oxidative phosphorylation, mitochondrial biogenesis and colorectal cancer Research Paper

Correction: Glucocorticoid impairs cell-cell communication by autophagy-mediated degradation of connexin 43 in osteocytes Correction

Dicer prevents genome instability in response to replication stress Research Paper

Dicer prevents genome instability in response to replication stress Research Paper

1,4-dihydroxy quininib attenuates growth of colorectal cancer cells and xenografts and regulates the TIE-2 signaling pathway in patient tumours Research Paper

Synergistic inhibition of tumor cell proliferation by metformin and mito-metformin in the presence of iron chelators Research Paper

Host targeted antiviral (HTA): functional inhibitor compounds of scaffold protein RACK1 inhibit herpes simplex virus proliferation Research Paper

Constitutive activation of EGFR is associated with tumor progression and plays a prominent role in malignant phenotype of chondrosarcoma Research Paper

Thyroid hormones induce doxorubicin chemosensitivity through enzymes involved in chemotherapy metabolism in lymphoma T cells Research Paper

The glutamate release inhibitor riluzole increases DNA damage and enhances cytotoxicity in human glioma cells, in vitro and in vivo Research Paper

PIM kinase inhibitor, AZD1208, inhibits protein translation and induces autophagy in primary chronic lymphocytic leukemia cells Research Paper

Characterization of cancer-associated IDH2 mutations that differ in tumorigenicity, chemosensitivity and 2-hydroxyglutarate production Research Paper

A state of stochastic cancer stemness through the CDK1-SOX2 axis Research Perspective

A novel anti-melanoma SRC-family kinase inhibitor Research Paper

HIGH expression of OSM and IL-6 are associated with decreased breast cancer survival: synergistic induction of IL-6 secretion by OSM and IL-1β Research Paper

AXL knockdown gene signature reveals a drug repurposing opportunity for a class of antipsychotics to reduce growth and metastasis of triple negative breast cancer Research Paper

Rigosertib ameliorates the effects of oncogenic KRAS signaling in a murine model of myeloproliferative neoplasia Research Paper

Phospho-ERK levels as predictors for chemotherapy of rectal carcinoma Research Paper

Statins affect human glioblastoma and other cancers through TGF-β inhibition Research Paper