The Oncosearch | Oncotarget

Over-activation of AKT signaling leading to 5-Fluorouracil resistance in SNU-C5/5-FU cells Research Paper

Eun-Ji Kim, Gyeoung-Jin Kang, Jung-Il Kang, Hye-Jin Boo, Jin Won Hyun, Young Sang Koh, Weon-Young Chang, Young Ree Kim, Jung-Mi Kwon, Young Hee Maeng, Eun-Sook Yoo, Chang Hoon Lee, Hee-Kyoung Kang

Published Apr 13, 2018 · Vol. 9, No. 28 · pp. 19911-19928

Gefitinib or lapatinib with foretinib synergistically induce a cytotoxic effect in melanoma cell lines Research Paper

Ewelina Dratkiewicz, Katarzyna Pietraszek-Gremplewicz, Aleksandra Simiczyjew, Antonina Joanna Mazur, Dorota Nowak

Published Apr 6, 2018 · Vol. 9, No. 26 · pp. 18254-18268

ONC201 kills breast cancer cells in vitro by targeting mitochondria Research Paper

Yoshimi Endo Greer, Natalie Porat-Shliom, Kunio Nagashima, Christina Stuelten, Dan Crooks, Vishal N. Koparde, Samuel F. Gilbert, Celia Islam, Ashley Ubaldini, Yun Ji, Luca Gattinoni, Ferri Soheilian, Xiantao Wang, Markus Hafner, Jyoti Shetty, Bao Tran, Parthav Jailwala, Maggie Cam, Martin Lang, Donna Voeller, William C. Reinhold, Vinodh Rajapakse, Yves Pommier, Roberto Weigert, W. Marston Linehan, Stanley Lipkowitz

Published Apr 6, 2018 · Vol. 9, No. 26 · pp. 18454-18479

PIK3CA mutation, reduced AKT serine 473 phosphorylation, and increased ERÎ± serine 167 phosphorylation are positive prognostic indicators in postmenopausal estrogen receptor-positive early breast cancer Research Paper

Naoko Ishida, Motoi Baba, Yutaka Hatanaka, Kanako Hagio, Hiromi Okada, Kanako C. Hatanaka, Kenichi Togashi, Yoshihiro Matsuno, Hiroko Yamashita

Published Apr 3, 2018 · Vol. 9, No. 25 · pp. 17711-17724

Novel drug-resistance mechanisms of pemetrexed-treated non-small cell lung cancer Research Paper

Ryosuke Tanino, Yukari Tsubata, Nanae Harashima, Mamoru Harada, Takeshi Isobe

Published Mar 30, 2018 · Vol. 9, No. 24 · pp. 16807-16821

Imaging markers of response to combined BRAF and MEK inhibition in BRAF mutated vemurafenib-sensitive and resistant melanomas Research Paper

Stefania Acciardo, Lionel Mignion, Nicolas Joudiou, Caroline Bouzin, Jean-FranÃ§ois Baurain, Bernard Gallez, BÃ©nÃ©dicte F. Jordan

Published Mar 30, 2018 · Vol. 9, No. 24 · pp. 16832-16846

Esophageal squamous cell carcinoma transcriptome reveals the effect of FOXM1 on patient outcome through novel PIK3R3 mediated activation of PI3K signaling pathway Research Paper

Pedro Nicolau-Neto, Nathalia Meireles Da Costa, Paulo Thiago de Souza Santos, Isabela Martins Gonzaga, Maria Aparecida Ferreira, Simone Guaraldi, Miguel Angelo Moreira, Hector N. SeuÃ¡nez, Lilian Brewer, Anke Bergmann, Mariana Boroni, Andre Luiz Mencalha, Cleber Dario Pinto Kruel, Sheila Coelho Soares Lima, Dominic Esposito, Tatiana Almeida SimÃ£o4, Luis Felipe Ribeiro Pinto

Published Mar 30, 2018 · Vol. 9, No. 24 · pp. 16634-16647

Transcriptional orchestration of mitochondrial homeostasis in a cellular model of PGC-1-related coactivator-dependent thyroid tumor Research Paper

Solenne Dumont, Soazig Le Pennec, Audrey Donnart, Raluca Teusan, Marja Steenman, Catherine Chevalier, RÃ©mi Houlgatte, FrÃ©dÃ©rique Savagner

Published Mar 23, 2018 · Vol. 9, No. 22 · pp. 15883-15894

ADAM17 inhibition enhances platinum efficiency in ovarian cancer Research Paper

Nina Hedemann, Christoph Rogmans, Susanne Sebens, Daniela Wesch, Manuel Reichert, Dirk Schmidt-Arras, Hans-Heinrich Oberg, Ulrich Pecks, Marion van Mackelenbergh, JÃ¶rg Weimer, Norbert Arnold, Nicolai Maass, Dirk O. Bauerschlag

Published Mar 23, 2018 · Vol. 9, No. 22 · pp. 16043-16058

Pertuzumab, trastuzumab and eribulin mesylate therapy for previously treated advanced HER2-positive breast cancer: a feasibility study with analysis of biomarkers Research Paper

Yasutaka Tono, Mikiya Ishihara, Yoshihiro Miyahara, Satoshi Tamaru, Hiroyasu Oda, Yoshiki Yamashita, Isao Tawara, Hiroaki Ikeda, Hiroshi Shiku, Toshiro Mizuno, Naoyuki Katayama

Published Mar 13, 2018 · Vol. 9, No. 19 · pp. 14909-14921

Modularity of the metabolic gene network as a prognostic biomarker for hepatocellular carcinoma Research Paper

Fengdan Ye, Dongya Jia, Mingyang Lu, Herbert Levine, Michael W. Deem

Published Mar 13, 2018 · Vol. 9, No. 19 · pp. 15015-15026

Calpastatin phosphorylation regulates radiation-induced calpain activity in glioblastoma Research Paper

Emily A. Bassett, Kamalakannan Palanichamy, Mitchell Pearson, Joseph P. McElroy, Saikh Jaharul Haque, Erica Hlavin Bell, Arnab Chakravarti

Published Mar 6, 2018 · Vol. 9, No. 18 · pp. 14597-14607

Interactome analysis of transforming growth factor-β-activated kinase 1 in Helicobacter pylori-infected cells revealed novel regulators tripartite motif 28 and CDC37 Research Paper

Olga Sokolova, Thilo KÃ¤hne, Kenneth Bryan, Michael Naumann

Published Mar 6, 2018 · Vol. 9, No. 18 · pp. 14366-14381

The protective autophagy activated by GANT-61 in MYCN amplified neuroblastoma cells is mediated by PERK Research Paper

Jing Wang, Siqi Huang, Ruicheng Tian, Jing Chen, Hongxiang Gao, Chenjie Xie, Yuhua Shan, Zhen Zhang, Song Gu, Min Xu

Published Mar 6, 2018 · Vol. 9, No. 18 · pp. 14413-14427

Disruption of ROCK1 gene restores autophagic flux and mitigates doxorubicin-induced cardiotoxicity Research Paper

Jianjian Shi, Michelle Surma, Lei Wei

Published Feb 8, 2018 · Vol. 9, No. 16 · pp. 12995-13008

CDK8/19 inhibition induces premature G1/S transition and ATR-dependent cell death in prostate cancer cells Research Paper

Akito Nakamura, Daisuke Nakata, Yuichi Kakoi, Mihoko Kunitomo, Saomi Murai, Shunsuke Ebara, Akito Hata, Takahito Hara

Published Feb 6, 2018 · Vol. 9, No. 17 · pp. 13474-13487

The enhanced susceptibility of ADAM-17 hypomorphic mice to DSS-induced colitis is not ameliorated by loss of RIPK3, revealing an unexpected function of ADAM-17 in necroptosis Research Paper

Johaiber Fuchslocher Chico, Maren Falk-Paulsen, Anne Luzius, Carina Saggau, Barbara Ruder, Julia Bolik, Dirk Schmidt-Arras, Andreas Linkermann, Christoph Becker, Philip Rosenstiel, Stefan Rose-John, Dieter Adam

Published Feb 5, 2018 · Vol. 9, No. 16 · pp. 12941-12958

Increased expression of MNK1b, the spliced isoform of MNK1, predicts poor prognosis and is associated with triple-negative breast cancer Research Paper

Celia Pinto-DÃez, Eva M. GarcÃa-Recio, M. Isabel PÃ©rez-Morgado, Marta GarcÃa-HernÃ¡ndez, Lara Sanz-Criado, Silvia SacristÃ¡n, M. Val Toledo-Lobo, BelÃ©n PÃ©rez-Mies, Isabel Esteban-RodrÃguez, Alejandro Pascual, Mercedes Garcia-Villanueva, Noelia MartÃnez-JaÃ±ez, VÃctor M. GonzÃ¡lez, M. Elena MartÃn

Published Feb 5, 2018 · Vol. 9, No. 17 · pp. 13501-13516

MiR-29b reverses oxaliplatin-resistance in colorectal cancer by targeting SIRT1 Research Paper

Hui Liu, Xin-Hua Cheng

Published Feb 1, 2018 · Vol. 9, No. 15 · pp. 12304-12315

Targeting angiogenesis in multiple myeloma by the VEGF and HGF blocking DARPin^Â® protein MP0250: a preclinical study Research Paper

Luigia Rao, Kim De Veirman, Donato Giannico, Ilaria Saltarella, Vanessa Desantis, Maria Antonia Frassanito, Antonio Giovanni Solimando, Domenico Ribatti, Marcella Prete, Andreas Harstrick, Ulrike Fiedler, Hendrik De Raeve, Vito Racanelli, Karin Vanderkerken, Angelo Vacca

Published Jan 30, 2018 · Vol. 9, No. 17 · pp. 13366-13381

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Over-activation of AKT signaling leading to 5-Fluorouracil resistance in SNU-C5/5-FU cells Research Paper

Gefitinib or lapatinib with foretinib synergistically induce a cytotoxic effect in melanoma cell lines Research Paper

ONC201 kills breast cancer cells in vitro by targeting mitochondria Research Paper

PIK3CA mutation, reduced AKT serine 473 phosphorylation, and increased ERÎ± serine 167 phosphorylation are positive prognostic indicators in postmenopausal estrogen receptor-positive early breast cancer Research Paper

Novel drug-resistance mechanisms of pemetrexed-treated non-small cell lung cancer Research Paper

Imaging markers of response to combined BRAF and MEK inhibition in BRAF mutated vemurafenib-sensitive and resistant melanomas Research Paper

Esophageal squamous cell carcinoma transcriptome reveals the effect of FOXM1 on patient outcome through novel PIK3R3 mediated activation of PI3K signaling pathway Research Paper

Transcriptional orchestration of mitochondrial homeostasis in a cellular model of PGC-1-related coactivator-dependent thyroid tumor Research Paper

ADAM17 inhibition enhances platinum efficiency in ovarian cancer Research Paper

Pertuzumab, trastuzumab and eribulin mesylate therapy for previously treated advanced HER2-positive breast cancer: a feasibility study with analysis of biomarkers Research Paper

Modularity of the metabolic gene network as a prognostic biomarker for hepatocellular carcinoma Research Paper

Calpastatin phosphorylation regulates radiation-induced calpain activity in glioblastoma Research Paper

Interactome analysis of transforming growth factor-β-activated kinase 1 in Helicobacter pylori-infected cells revealed novel regulators tripartite motif 28 and CDC37 Research Paper

The protective autophagy activated by GANT-61 in MYCN amplified neuroblastoma cells is mediated by PERK Research Paper

Disruption of ROCK1 gene restores autophagic flux and mitigates doxorubicin-induced cardiotoxicity Research Paper

CDK8/19 inhibition induces premature G1/S transition and ATR-dependent cell death in prostate cancer cells Research Paper

The enhanced susceptibility of ADAM-17 hypomorphic mice to DSS-induced colitis is not ameliorated by loss of RIPK3, revealing an unexpected function of ADAM-17 in necroptosis Research Paper

Increased expression of MNK1b, the spliced isoform of MNK1, predicts poor prognosis and is associated with triple-negative breast cancer Research Paper

MiR-29b reverses oxaliplatin-resistance in colorectal cancer by targeting SIRT1 Research Paper

Targeting angiogenesis in multiple myeloma by the VEGF and HGF blocking DARPin^Â® protein MP0250: a preclinical study Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Over-activation of AKT signaling leading to 5-Fluorouracil resistance in SNU-C5/5-FU cells Research Paper

Gefitinib or lapatinib with foretinib synergistically induce a cytotoxic effect in melanoma cell lines Research Paper

ONC201 kills breast cancer cells in vitro by targeting mitochondria Research Paper

PIK3CA mutation, reduced AKT serine 473 phosphorylation, and increased ERÎ± serine 167 phosphorylation are positive prognostic indicators in postmenopausal estrogen receptor-positive early breast cancer Research Paper

Novel drug-resistance mechanisms of pemetrexed-treated non-small cell lung cancer Research Paper

Imaging markers of response to combined BRAF and MEK inhibition in BRAF mutated vemurafenib-sensitive and resistant melanomas Research Paper

Esophageal squamous cell carcinoma transcriptome reveals the effect of FOXM1 on patient outcome through novel PIK3R3 mediated activation of PI3K signaling pathway Research Paper

Transcriptional orchestration of mitochondrial homeostasis in a cellular model of PGC-1-related coactivator-dependent thyroid tumor Research Paper

ADAM17 inhibition enhances platinum efficiency in ovarian cancer Research Paper

Pertuzumab, trastuzumab and eribulin mesylate therapy for previously treated advanced HER2-positive breast cancer: a feasibility study with analysis of biomarkers Research Paper

Modularity of the metabolic gene network as a prognostic biomarker for hepatocellular carcinoma Research Paper

Calpastatin phosphorylation regulates radiation-induced calpain activity in glioblastoma Research Paper

Interactome analysis of transforming growth factor-β-activated kinase 1 in Helicobacter pylori-infected cells revealed novel regulators tripartite motif 28 and CDC37 Research Paper

The protective autophagy activated by GANT-61 in MYCN amplified neuroblastoma cells is mediated by PERK Research Paper

Disruption of ROCK1 gene restores autophagic flux and mitigates doxorubicin-induced cardiotoxicity Research Paper

CDK8/19 inhibition induces premature G1/S transition and ATR-dependent cell death in prostate cancer cells Research Paper

The enhanced susceptibility of ADAM-17 hypomorphic mice to DSS-induced colitis is not ameliorated by loss of RIPK3, revealing an unexpected function of ADAM-17 in necroptosis Research Paper

Increased expression of MNK1b, the spliced isoform of MNK1, predicts poor prognosis and is associated with triple-negative breast cancer Research Paper

MiR-29b reverses oxaliplatin-resistance in colorectal cancer by targeting SIRT1 Research Paper

Targeting angiogenesis in multiple myeloma by the VEGF and HGF blocking DARPinÂ® protein MP0250: a preclinical study Research Paper

Targeting angiogenesis in multiple myeloma by the VEGF and HGF blocking DARPin^Â® protein MP0250: a preclinical study Research Paper