The Oncosearch | Oncotarget

Caveolin-1 Y14 phosphorylation suppresses tumor growth while promoting invasion Research Paper

Bharat Joshi, Judy Pawling, Jay Shankar, Karina Pacholczyk, Yohan Kim, Wynn Tran, Fanrui Meng, Anas M. Abdel Rahman, Leonard J. Foster, Hon S. Leong, James W. Dennis, Ivan R. Nabi

Published Nov 19, 2019 · Vol. 10, No. 62 · pp. 6668-6677

Keywords: caveolin-1, TP53, tumor suppressor, tumor cell metabolism, invadopodia

A squalamine derivative, NV669, as a novel PTP1B inhibitor: in vitro and in vivo effects on pancreatic and hepatic tumor growth Research Paper

Sylvie Carmona, Jean-Michel Brunel, Rénaté Bonier, Véronique Sbarra, Stéphane Robert, Patrick Borentain, Dominique Lombardo, Eric Mas, René Gerolami

Published Nov 19, 2019 · Vol. 10, No. 62 · pp. 6651-6667

Keywords: aminosterol, pancreas, liver, PTP1B, cancer

The long non-coding RNA PCA3: an update of its functions and clinical applications as a biomarker in prostate cancer Review

Ana Emília Goulart Lemos, Aline da Rocha Matos, Luciana Bueno Ferreira, Etel Rodrigues Pereira Gimba

Published Nov 12, 2019 · Vol. 10, No. 61 · pp. 6589-6603

Keywords: PCA3, prostate cancer, biomarker, long non-coding RNA (lncRNA), clinical applications

The multikinase inhibitor RXDX-105 is effective against neuroblastoma in vitro and in vivo Research Paper

Sean M. Flynn, Jacqueline Lesperance, Andrew Macias, Nikki Phanhthilath, Megan Rose Paul, Jong Wook Kim, Pablo Tamayo, Peter E. Zage

Published Oct 29, 2019 · Vol. 10, No. 59 · pp. 6323-6333

Keywords: neuroblastoma, RXDX-105, CEP-32496, RET, BRAF

Central nervous system-specific efficacy of CDK4/6 inhibitors in randomized controlled trials for metastatic breast cancer Research Paper

Long V. Nguyen, Karlee Searle, Katarzyna J. Jerzak

Published Oct 29, 2019 · Vol. 10, No. 59 · pp. 6317-6322

Keywords: breast neoplasms, blood-brain barrier, palbociclib, ribociclib, abemaciclib

Correction: Pharmacological treatment with inhibitors of nuclear export enhances the antitumor activity of docetaxel in human prostate cancer Correction

Giovanni Luca Gravina, Andrea Mancini, Alessandro Colapietro, Francesco Marampon, Roberta Sferra, Simona Pompili, Leda Assunta Biordi, Roberto Iorio, Vincenzo Flati, Christian Argueta, Yosef Landesman, Michael Kauffman, Sharon Shacham, Claudio Festuccia

Published Oct 22, 2019 · Vol. 10, No. 59 · pp. 6393-6395

Correction: SETD2 loss sensitizes cells to PI3Kβ and AKT inhibition Correction

Esteban A. Terzo, Aaron R. Lim, Anna Chytil, Yun Chen Chiang, Leah Farmer, Kathryn H. Gessner, Cheryl Lyn Walker, Valerie M. Jansen, W. Kimryn Rathmell

Published Oct 22, 2019 · Vol. 10, No. 59 · pp. 6391-6392

Kallikrein 6 protease advances colon tumorigenesis via induction of the high mobility group A2 protein Research Paper

Hwudaurw Chen, Earlphia Sells, Ritu Pandey, Edward R. Abril, Chiu-Hsieh Hsu, Robert S. Krouse, Raymond B. Nagle, Georgios Pampalakis, Georgia Sotiropoulou, Natalia A. Ignatenko

Published Oct 22, 2019 · Vol. 10, No. 58 · pp. 6062-6078

Keywords: colorectal cancer, kallikrein-related peptidase 6 or KLK6, SMAD2/3, epithelial-mesenchymal transition, HMGA2

Mutation of the co-chaperone Tsc1 in bladder cancer diminishes Hsp90 acetylation and reduces drug sensitivity and selectivity Research Paper

Mark R. Woodford, Michael Hughes, Rebecca A. Sager, Sarah J. Backe, Alexander J. Baker-Williams, Michael S. Bratslavsky, Joseph M. Jacob, Oleg Shapiro, Michael Wong, Gennady Bratslavsky, Dimitra Bourboulia, Mehdi Mollapour

Published Oct 8, 2019 · Vol. 10, No. 56 · pp. 5824-5834

Keywords: tuberous sclerosis complex (TSC), Tsc1 (Hamartin), Tsc2 (Tuberin), heat shock protein (Hsp90), bladder cancer

GCN5 HAT inhibition reduces human Burkitt lymphoma cell survival through reduction of MYC target gene expression and impeding BCR signaling pathways Research Paper

Aimee T. Farria, Lisa Maria Mustachio, Zeynep H. Coban Akdemir, Sharon Y.R. Dent

Published Oct 8, 2019 · Vol. 10, No. 56 · pp. 5847-5858

Keywords: GCN5, MYC, lymphoma, BCR

SRC mediates cell cycle regulatory function of Pin1 and is a rational target in treating mucinous ovarian cancer Research Paper

Elisabeth Baron, Shubai Liu, Yuanyuan Hua, Junzheng Yang, Pui-Wah Choi, Wing-Chung Ng, Shu-Kay Ng, Jinyan Du, Charlene C. Ng, Xiao Zhen Zhou, Kun Ping Lu, William R. Welch, Christopher P. Crum, Ross S. Berkowitz, Shu-Wing Ng

Published Sep 3, 2019 · pp. 5724-5736

Keywords: cell cycle regulation, drug sensitivity, ovarian cancer, signal transduction, combination treatment

A novel tumor spheroid model identifies selective enhancement of radiation by an inhibitor of oxidative phosphorylation Research Paper

Henning Karlsson, Wojciech Senkowski, Mårten Fryknäs, Sharmineh Mansoori, Stig Linder, Joachim Gullbo, Rolf Larsson, Peter Nygren

Published Sep 3, 2019 · Vol. 10, No. 51 · pp. 5372-5382

Keywords: spheroid, tumor model, high-throughput, radiosensitizer, hypoxia

DS-1205b, a novel selective inhibitor of AXL kinase, blocks resistance to EGFR-tyrosine kinase inhibitors in a non-small cell lung cancer xenograft model Research Paper

Takeshi Jimbo, Mana Hatanaka, Takahiro Komatsu, Tomoe Taira, Kentaro Kumazawa, Naoyuki Maeda, Takashi Suzuki, Masahiro Ota, Noriyasu Haginoya, Takeshi Isoyama, Kosaku Fujiwara

Published Aug 27, 2019 · Vol. 10, No. 50 · pp. 5152-5167

Keywords: AXL, DS-1205, EGFR-TKI resistance, erlotinib, osimertinib

Neurotensin as a source of cyclic AMP and co-mitogen in fibrolamellar hepatocellular carcinoma Research Paper

Kimberly J. Riehle, Heidi L. Kenerson, Kevin M. Riggle, Rigney Turnham, Kevin Sullivan, Renay Bauer, John D. Scott, Raymond S. Yeung

Published Aug 20, 2019 · Vol. 10, No. 49 · pp. 5092-5102

Keywords: liver cancer, protein kinase A, fibrolamellar, neurotensin, epidermal growth factor

PTEN interacts with RNA polymerase II to dephosphorylate polymerase II C-terminal domain Research Paper

Ata Abbas, Todd Romigh, Charis Eng

Published Aug 13, 2019 · Vol. 10, No. 48 · pp. 4951-4959

Keywords: phosphatase and tensin homolog (PTEN), cowden syndrome, PTEN hamartoma tumor syndrome, RNA polymerase II, Pol II CTD dephosphorylation

V-ATPase-associated prorenin receptor is upregulated in prostate cancer after PTEN loss Research Paper

Amro H. Mohammad, Sarah Assadian, Frédéric Couture, Karen J. Lefebvre, Wissal El-Assaad, Veronique Barrès, Veronique Ouellet, Pierre-Luc Boulay, Jieyi Yang, Mathieu Latour, Luc Furic, William Muller, Nahum Sonenberg, Anne-Marie Mes-Masson, Fred Saad, Robert Day, Jose G. Teodoro

Published Aug 13, 2019 · Vol. 10, No. 48 · pp. 4923-4936

Keywords: prostate cancer, PTEN, prorenin receptor, soluble prorenin receptor, V-ATPase complex

Inactivation of beta1 integrin induces proteasomal degradation of Myc oncoproteins Research Paper

Manabu Sasada, Takuya Iyoda, Tatsufumi Asayama, Yusuke Suenaga, Shunsuke Sakai, Naoya Kase, Hiroaki Kodama, Sana Yokoi, Yoichiro Isohama, Fumio Fukai

Published Aug 13, 2019 · Vol. 10, No. 48 · pp. 4960-4972

Keywords: integrin, Myc, proteasomal degradation, fibronectin, neuroblastoma

Reduced chemotherapeutic sensitivity in high glucose condition: implication of antioxidant response Research Paper

Alessia Garufi, Gianandrea Traversi, Maria Saveria Gilardini Montani, Valerio D’Orazi, Giuseppa Pistritto, Mara Cirone, Gabriella D’Orazi

Published Jul 23, 2019 · Vol. 10, No. 45 · pp. 4691-4702

Keywords: chemoresistance, reactive oxygen species (ROS), high glucose (HG), cancer, nuclear factor erythroid 2-related factor 2 (NRF2)

Peptide microarray of pediatric acute myeloid leukemia is related to relapse and reveals involvement of DNA damage response and repair Research Paper

Hasan Mahmud, Arja ter Elst, Frank J.G. Scherpen, Tiny Meeuwsen-de Boer, Kim R. Kampen, Valérie de Haas, Victor Guryev, Maikel M. Peppelenbosch, Steven M. Kornblau, Eveline S.J.M. de Bont

Published Jul 23, 2019 · Vol. 10, No. 45 · pp. 4679-4690

Keywords: AML, leukemia, peptide microarray, DNA damage and repair, signal transduction

Dicer prevents genome instability in response to replication stress Research Paper

Michalis Fragkos, Viviana Barra, Tom Egger, Benoit Bordignon, Delphine Lemacon, Valeria Naim, Arnaud Coquelle

Published Jul 9, 2019 · Vol. 10, No. 43 · pp. 4407-4423

Keywords: replication stress, common fragile sites, Dicer, genomic instability

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Caveolin-1 Y14 phosphorylation suppresses tumor growth while promoting invasion Research Paper

A squalamine derivative, NV669, as a novel PTP1B inhibitor: in vitro and in vivo effects on pancreatic and hepatic tumor growth Research Paper

The long non-coding RNA PCA3: an update of its functions and clinical applications as a biomarker in prostate cancer Review

The multikinase inhibitor RXDX-105 is effective against neuroblastoma in vitro and in vivo Research Paper

Central nervous system-specific efficacy of CDK4/6 inhibitors in randomized controlled trials for metastatic breast cancer Research Paper

Correction: Pharmacological treatment with inhibitors of nuclear export enhances the antitumor activity of docetaxel in human prostate cancer Correction

Correction: SETD2 loss sensitizes cells to PI3Kβ and AKT inhibition Correction

Kallikrein 6 protease advances colon tumorigenesis via induction of the high mobility group A2 protein Research Paper

Mutation of the co-chaperone Tsc1 in bladder cancer diminishes Hsp90 acetylation and reduces drug sensitivity and selectivity Research Paper

GCN5 HAT inhibition reduces human Burkitt lymphoma cell survival through reduction of MYC target gene expression and impeding BCR signaling pathways Research Paper

SRC mediates cell cycle regulatory function of Pin1 and is a rational target in treating mucinous ovarian cancer Research Paper

A novel tumor spheroid model identifies selective enhancement of radiation by an inhibitor of oxidative phosphorylation Research Paper

DS-1205b, a novel selective inhibitor of AXL kinase, blocks resistance to EGFR-tyrosine kinase inhibitors in a non-small cell lung cancer xenograft model Research Paper

Neurotensin as a source of cyclic AMP and co-mitogen in fibrolamellar hepatocellular carcinoma Research Paper

PTEN interacts with RNA polymerase II to dephosphorylate polymerase II C-terminal domain Research Paper

V-ATPase-associated prorenin receptor is upregulated in prostate cancer after PTEN loss Research Paper

Inactivation of beta1 integrin induces proteasomal degradation of Myc oncoproteins Research Paper

Reduced chemotherapeutic sensitivity in high glucose condition: implication of antioxidant response Research Paper

Peptide microarray of pediatric acute myeloid leukemia is related to relapse and reveals involvement of DNA damage response and repair Research Paper

Dicer prevents genome instability in response to replication stress Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Caveolin-1 Y14 phosphorylation suppresses tumor growth while promoting invasion Research Paper

A squalamine derivative, NV669, as a novel PTP1B inhibitor: in vitro and in vivo effects on pancreatic and hepatic tumor growth Research Paper

The long non-coding RNA PCA3: an update of its functions and clinical applications as a biomarker in prostate cancer Review

The multikinase inhibitor RXDX-105 is effective against neuroblastoma in vitro and in vivo Research Paper

Central nervous system-specific efficacy of CDK4/6 inhibitors in randomized controlled trials for metastatic breast cancer Research Paper

Correction: Pharmacological treatment with inhibitors of nuclear export enhances the antitumor activity of docetaxel in human prostate cancer Correction

Correction: SETD2 loss sensitizes cells to PI3Kβ and AKT inhibition Correction

Kallikrein 6 protease advances colon tumorigenesis via induction of the high mobility group A2 protein Research Paper

Mutation of the co-chaperone Tsc1 in bladder cancer diminishes Hsp90 acetylation and reduces drug sensitivity and selectivity Research Paper

GCN5 HAT inhibition reduces human Burkitt lymphoma cell survival through reduction of MYC target gene expression and impeding BCR signaling pathways Research Paper

SRC mediates cell cycle regulatory function of Pin1 and is a rational target in treating mucinous ovarian cancer Research Paper

A novel tumor spheroid model identifies selective enhancement of radiation by an inhibitor of oxidative phosphorylation Research Paper

DS-1205b, a novel selective inhibitor of AXL kinase, blocks resistance to EGFR-tyrosine kinase inhibitors in a non-small cell lung cancer xenograft model Research Paper

Neurotensin as a source of cyclic AMP and co-mitogen in fibrolamellar hepatocellular carcinoma Research Paper

PTEN interacts with RNA polymerase II to dephosphorylate polymerase II C-terminal domain Research Paper

V-ATPase-associated prorenin receptor is upregulated in prostate cancer after PTEN loss Research Paper

Inactivation of beta1 integrin induces proteasomal degradation of Myc oncoproteins Research Paper

Reduced chemotherapeutic sensitivity in high glucose condition: implication of antioxidant response Research Paper

Peptide microarray of pediatric acute myeloid leukemia is related to relapse and reveals involvement of DNA damage response and repair Research Paper

Dicer prevents genome instability in response to replication stress Research Paper