The Oncosearch | Oncotarget

Molecular architecture of the ErbB2 extracellular domain homodimer Research Paper

Shi Hu, Yuna Sun, Yanchun Meng, Xiaoze Wang, Weili Yang, Wenyan Fu, Huaizu Guo, Weizhu Qian, Sheng Hou, Bohua Li, Zihe Rao, Zhiyong Lou, Yajun Guo

Published Jan 30, 2015 · Vol. 6, No. 3 · pp. 1695-1706

Keywords: ErbB2, dimerization, signal transduction, crystal structure, Oncogene

PP2A inhibition determines poor outcome and doxorubicin resistance in early breast cancer and its activation shows promising therapeutic effects Research Paper

RaÃºl RincÃ³n, Ion CristÃ³bal, Sandra Zazo, Oriol ArpÃ, Silvia MenÃ©ndez, Rebeca Manso, Ana Lluch, Pilar Eroles, Ana Rovira, Joan Albanell, JesÃºs GarcÃa-Foncillas, Juan Madoz-GÃºrpide, Federico Rojo

Published Jan 30, 2015 · Vol. 6, No. 6 · pp. 4299-4314

Inhibition of PI3K/AKT/mTOR axis disrupts oxidative stress-mediated survival of melanoma cells Research Paper

Heather G. Hambright, Peng Meng, Addanki P. Kumar, Rita Ghosh

Published Jan 29, 2015 · Vol. 6, No. 9 · pp. 7195-7208

Computational design, chemical synthesis, and biological evaluation of a novel ERK inhibitor (BL-EI001) with apoptosis-inducing mechanisms in breast cancer Research Paper

Bo Liu, Leilei Fu, Cui Zhang, Lan Zhang, Yonghui Zhang, Liang Ouyang, Gu He, Jian Huang

Published Jan 27, 2015 · Vol. 6, No. 9 · pp. 6762-6775

Group I Paks as therapeutic targets in NF2-deficient meningioma Research Paper

Hoi-Yee Chow, Biao Dong, Sergio G. Duron, David A. Campbell, Christy C. Ong, Klaus P. Hoeflich, Long-Sheng Chang, D. Bradley Welling, Zeng-jie Yang, Jonathan Chernoff

Published Jan 24, 2015 · Vol. 6, No. 4 · pp. 1981-1994

A new chemical inhibitor of angiogenesis and tumorigenesis that targets the VEGF signaling pathway upstream of Ras Research Paper

AgnÃ¨s Desroches-Castan, Delphine QuÃ©lard, Martine Demeunynck, Jean-FranÃ§ois Constant, Chongling Dong, Michelle Keramidas, Jean-Luc Coll, Caroline Barette, Laurence LafanechÃ¨re, Jean-Jacques Feige

Published Jan 23, 2015 · Vol. 6, No. 7 · pp. 5382-5411

The histidine-rich calcium binding protein (HRC) promotes tumor metastasis in hepatocellular carcinoma and is upregulated by SATB1 Research Paper

Jingmei Liu, Ping Han, Mengke Li, Wei Yan, Jin Liu, Jiqiao Liu, Jiayi He, Wei Tu, Yujia Xia, Zhenzhen Zhou, Jin Gong, Mei Liu, Qiang Ding, Dean Tian

Published Jan 22, 2015 · Vol. 6, No. 9 · pp. 6811-6824

GATA1 induces epithelial-mesenchymal transition in breast cancer cells through PAK5 oncogenic signaling Research Paper

Yang Li, Qiang Ke, Yangguang Shao, Ge Zhu, Yanshu Li, Nanxi Geng, Feng Jin, Feng Li

Published Jan 21, 2015 · Vol. 6, No. 6 · pp. 4345-4356

EBNA3C regulates p53 through induction of Aurora kinase B Research Paper

Hem C. Jha, Karren Yang, Darine W. El-Naccache, Zhiguo Sun, Erle S. Robertson

Published Jan 21, 2015 · Vol. 6, No. 8 · pp. 5788-5803

Initiation of esophageal squamous cell carcinoma (ESCC) in a murine 4-nitroquinoline-1-oxide and alcohol carcinogenesis model Research Paper

Kwame Osei-Sarfo, Alison M. Urvalek, Xiao-Han Tang, Theresa Scognamiglio, Lorraine J. Gudas

Published Jan 21, 2015 · Vol. 6, No. 8 · pp. 6040-6052

Carboxyl-terminal domain of MUC16 imparts tumorigenic and metastatic functions through nuclear translocation of JAK2 to pancreatic cancer cells Research Paper

Srustidhar Das, Satyanarayana Rachagani, Maria P. Torres-Gonzalez, Imayavaramban Lakshmanan, Prabin D. Majhi, Lynette M. Smith, Kay-Uwe Wagner, Surinder K. Batra

Published Jan 21, 2015 · Vol. 6, No. 8 · pp. 5772-5787

EBV-LMP1 targeted DNAzyme enhances radiosensitivity by inhibiting tumor angiogenesis via the JNKs/HIF-1 pathway in nasopharyngeal carcinoma Research Paper

Lifang Yang, Liyu Liu, Zhijie Xu, Weihua Liao, Deyun Feng, Xin Dong, San Xu, Lanbo Xiao, Jingchen Lu, Xiangjian Luo, Min Tang, Ann M. Bode, Zigang Dong, Lunquan Sun, Ya Cao

Published Jan 21, 2015 · Vol. 6, No. 8 · pp. 5804-5817

Afatinib increases sensitivity to radiation in non-small cell lung cancer cells with acquired EGFR T790M mutation Research Paper

Shirong Zhang, Xiaoliang Zheng, Haixiu Huang, Kan Wu, Bing Wang, Xufeng Chen, Shenglin Ma

Published Jan 21, 2015 · Vol. 6, No. 8 · pp. 5832-5845

Identification of the oncogenic kinase TOPK/PBK as a master mitotic regulator of C2H2 zinc finger proteins Research Paper

Raed Rizkallah, Paratchata Batsomboon, Gregory B. Dudley, Myra M. Hurt

Published Jan 13, 2015 · Vol. 6, No. 3 · pp. 1446-1461

Keywords: Kinase, Mitosis, Phosphorylation, C2H2, Zinc Finger Proteins, TOPK/PBK.

Overexpression of N-terminal kinase like gene promotes tumorigenicity of hepatocellular carcinoma by regulating cell cycle progression and cell motility Research Paper

Jian Wang, Ming Liu, Leilei Chen, Tim Hon Man Chan, Lingxi Jiang, Yun-Fei Yuan, Xin-Yuan Guan

Published Jan 10, 2015 · Vol. 6, No. 3 · pp. 1618-1630

Keywords: HCC, NTKL, CHD1L, dynamin2, metastasis.

LCK over-expression drives STAT5 oncogenic signaling in PAX5 translocated BCP-ALL patients Research Paper

Valeria Cazzaniga, Cristina Bugarin, Michela Bardini, Marco Giordan, Geertruy te Kronnie, Giuseppe Basso, Andrea Biondi, Grazia Fazio, Giovanni Cazzaniga

Published Jan 8, 2015 · Vol. 6, No. 3 · pp. 1569-1581

Inhibition of the Warburg effect with a natural compound reveals a novel measurement for determining the metastatic potential of breast cancers Research Paper

Ritu Arora, David Schmitt, Balasubramanyam Karanam, Ming Tan, Clayton Yates, Windy Dean-Colomb

Published Jan 7, 2015 · Vol. 6, No. 2 · pp. 662-678

The soybean-derived peptide lunasin inhibits non-small cell lung cancer cell proliferation by suppressing phosphorylation of the retinoblastoma protein Research Paper

Elizabeth J. McConnell, Bharat Devapatla, Kavitha Yaddanapudi, Keith R. Davis

Published Dec 31, 2014 · Vol. 6, No. 7 · pp. 4649-4662

Inhibition of EP2/EP4 signaling abrogates IGF-1R-mediated cancer cell growth: Involvement of protein kinase C-Î¸ activation Research Paper

Tetsuyuki Takahashi, Hisanori Uehara, Hirohisa Ogawa, Hitomi Umemoto, Yoshimi Bando, Keisuke Izumi

Published Dec 31, 2014 · Vol. 6, No. 7 · pp. 4829-4844

Novel oral histone deacetylase inhibitor, MPT0E028, displays potent growth-inhibitory activity against human B-cell lymphoma in vitro and in vivo Research Paper

Han-Li Huang, Chieh-Yu Peng, Mei-Jung Lai, Chun-Han Chen, Hsueh-Yun Lee, Jing-Chi Wang, Jing-Ping Liou, Shiow-Lin Pan, Che-Ming Teng

Published Dec 31, 2014 · Vol. 6, No. 7 · pp. 4976-4991

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Molecular architecture of the ErbB2 extracellular domain homodimer Research Paper

PP2A inhibition determines poor outcome and doxorubicin resistance in early breast cancer and its activation shows promising therapeutic effects Research Paper

Inhibition of PI3K/AKT/mTOR axis disrupts oxidative stress-mediated survival of melanoma cells Research Paper

Computational design, chemical synthesis, and biological evaluation of a novel ERK inhibitor (BL-EI001) with apoptosis-inducing mechanisms in breast cancer Research Paper

Group I Paks as therapeutic targets in NF2-deficient meningioma Research Paper

A new chemical inhibitor of angiogenesis and tumorigenesis that targets the VEGF signaling pathway upstream of Ras Research Paper

The histidine-rich calcium binding protein (HRC) promotes tumor metastasis in hepatocellular carcinoma and is upregulated by SATB1 Research Paper

GATA1 induces epithelial-mesenchymal transition in breast cancer cells through PAK5 oncogenic signaling Research Paper

EBNA3C regulates p53 through induction of Aurora kinase B Research Paper

Initiation of esophageal squamous cell carcinoma (ESCC) in a murine 4-nitroquinoline-1-oxide and alcohol carcinogenesis model Research Paper

Carboxyl-terminal domain of MUC16 imparts tumorigenic and metastatic functions through nuclear translocation of JAK2 to pancreatic cancer cells Research Paper

EBV-LMP1 targeted DNAzyme enhances radiosensitivity by inhibiting tumor angiogenesis via the JNKs/HIF-1 pathway in nasopharyngeal carcinoma Research Paper

Afatinib increases sensitivity to radiation in non-small cell lung cancer cells with acquired EGFR T790M mutation Research Paper

Identification of the oncogenic kinase TOPK/PBK as a master mitotic regulator of C2H2 zinc finger proteins Research Paper

Overexpression of N-terminal kinase like gene promotes tumorigenicity of hepatocellular carcinoma by regulating cell cycle progression and cell motility Research Paper

LCK over-expression drives STAT5 oncogenic signaling in PAX5 translocated BCP-ALL patients Research Paper

Inhibition of the Warburg effect with a natural compound reveals a novel measurement for determining the metastatic potential of breast cancers Research Paper

The soybean-derived peptide lunasin inhibits non-small cell lung cancer cell proliferation by suppressing phosphorylation of the retinoblastoma protein Research Paper

Inhibition of EP2/EP4 signaling abrogates IGF-1R-mediated cancer cell growth: Involvement of protein kinase C-Î¸ activation Research Paper

Novel oral histone deacetylase inhibitor, MPT0E028, displays potent growth-inhibitory activity against human B-cell lymphoma in vitro and in vivo Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Molecular architecture of the ErbB2 extracellular domain homodimer Research Paper

PP2A inhibition determines poor outcome and doxorubicin resistance in early breast cancer and its activation shows promising therapeutic effects Research Paper

Inhibition of PI3K/AKT/mTOR axis disrupts oxidative stress-mediated survival of melanoma cells Research Paper

Computational design, chemical synthesis, and biological evaluation of a novel ERK inhibitor (BL-EI001) with apoptosis-inducing mechanisms in breast cancer Research Paper

Group I Paks as therapeutic targets in NF2-deficient meningioma Research Paper

A new chemical inhibitor of angiogenesis and tumorigenesis that targets the VEGF signaling pathway upstream of Ras Research Paper

The histidine-rich calcium binding protein (HRC) promotes tumor metastasis in hepatocellular carcinoma and is upregulated by SATB1 Research Paper

GATA1 induces epithelial-mesenchymal transition in breast cancer cells through PAK5 oncogenic signaling Research Paper

EBNA3C regulates p53 through induction of Aurora kinase B Research Paper

Initiation of esophageal squamous cell carcinoma (ESCC) in a murine 4-nitroquinoline-1-oxide and alcohol carcinogenesis model Research Paper

Carboxyl-terminal domain of MUC16 imparts tumorigenic and metastatic functions through nuclear translocation of JAK2 to pancreatic cancer cells Research Paper

EBV-LMP1 targeted DNAzyme enhances radiosensitivity by inhibiting tumor angiogenesis via the JNKs/HIF-1 pathway in nasopharyngeal carcinoma Research Paper

Afatinib increases sensitivity to radiation in non-small cell lung cancer cells with acquired EGFR T790M mutation Research Paper

Identification of the oncogenic kinase TOPK/PBK as a master mitotic regulator of C2H2 zinc finger proteins Research Paper

Overexpression of N-terminal kinase like gene promotes tumorigenicity of hepatocellular carcinoma by regulating cell cycle progression and cell motility Research Paper

LCK over-expression drives STAT5 oncogenic signaling in PAX5 translocated BCP-ALL patients Research Paper

Inhibition of the Warburg effect with a natural compound reveals a novel measurement for determining the metastatic potential of breast cancers Research Paper

The soybean-derived peptide lunasin inhibits non-small cell lung cancer cell proliferation by suppressing phosphorylation of the retinoblastoma protein Research Paper

Inhibition of EP2/EP4 signaling abrogates IGF-1R-mediated cancer cell growth: Involvement of protein kinase C-Î¸ activation Research Paper

Novel oral histone deacetylase inhibitor, MPT0E028, displays potent growth-inhibitory activity against human B-cell lymphoma in vitro and in vivo Research Paper