The Oncosearch | Oncotarget

Acquisition of resistance to trastuzumab in gastric cancer cells is associated with activation of IL-6/STAT3/Jagged-1/Notch positive feedback loop Research Paper

Zhengyan Yang, Liang Guo, Dan Liu, Limin Sun, Hongyu Chen, Que Deng, Yanjun Liu, Ming Yu, Yuanfang Ma, Ning Guo, Ming Shi

Published Dec 31, 2014 · Vol. 6, No. 7 · pp. 5072-5087

DEPTOR has growth suppression activity against pancreatic cancer cells Research Paper

Hua Li, Grace Y. Sun, Yongchao Zhao, Dafydd Thomas, Joel K. Greenson, Mark M. Zalupski, Edgar Ben-Josef, Yi Sun

Published Dec 30, 2014 · Vol. 5, No. 24 · pp. 12811-12819

Keywords: DEPTOR, mTOR pathway, pancreatic cancer, growth suppression

Autophagy through 4EBP1 and AMPK regulates oxidative stress-induced premature senescence in auditory cells Research Paper

Nana Akagi Tsuchihashi, Ken Hayashi, Katsuaki Dan, Fumiyuki Goto, Yasuyuki Nomura, Masato Fujioka, Sho Kanzaki, Shizuo Komune, Kaoru Ogawa

Published Dec 30, 2014 · Vol. 6, No. 6 · pp. 3644-3655

Keywords: premature senescence, autophagy, AMPK, oxidative stress, auditory cell

Paracrine SDF-1Î± signaling mediates the effects of PSCs on GEM chemoresistance through an IL-6 autocrine loop in pancreatic cancer cells Research Paper

Hui Zhang, Huanwen Wu, Jian Guan, Li Wang, Xinyu Ren, Xiaohua Shi, Zhiyong Liang, Tonghua Liu

Published Dec 30, 2014 · Vol. 6, No. 5 · pp. 3085-3097

Tumor promoter-induced cellular senescence: cell cycle arrest followed by geroconversion Research Paper

Olga V. Leontieva, Mikhail V. Blagosklonny

Published Dec 29, 2014 · Vol. 5, No. 24 · pp. 12715-12727

Metabolic reprogramming of metastatic breast cancer and melanoma by let-7a microRNA Research Paper

Anastassia Serguienko, Iwona Grad, Anna B. WennerstrÃ¸m, Leonardo A. Meza-Zepeda, Bernd Thiede, Eva W. Stratford, Ola Myklebost, Else Munthe

Published Dec 29, 2014 · Vol. 6, No. 4 · pp. 2451-2465

Ferroxitosis: A cell death from modulation of oxidative phosphorylation and PKM2-dependent glycolysis in melanoma Research Paper

Alexander J. Lakhter, James Hamilton, Pierre C. Dagher, Suresh Mukkamala, Takashi Hato, X. Charlie Dong, Lindsey D. Mayo, Robert A. Harris, Anantha Shekhar, Mircea Ivan, Nickolay Brustovetsky, Samisubbu R. Naidu

Published Dec 26, 2014 · Vol. 5, No. 24 · pp. 12694-12703

Expression of the potential therapeutic target CXXC5 in primary acute myeloid leukemia cells - high expression is associated with adverse prognosis as well as altered intracellular signaling and transcriptional regulation Research Paper

Ã˜ystein Bruserud, HÃ¥kon Reikvam, Hanne Fredly, JÃ¸rn Skavland, Karen-Marie Hagen, Tuyen Thy van Hoang, Annette K. Brenner, Amir Kadi, Audrey Astori, BjÃ¸rn Tore Gjertsen, Frederic Pendino

Published Dec 26, 2014 · Vol. 6, No. 5 · pp. 2794-2811

Elevated Src family kinase activity stabilizes E-cadherin-based junctions and collective movement of head and neck squamous cell carcinomas Research Paper

Laurence Veracini, Dominique Grall, SÃ©bastien Schaub, StÃ©phanie Beghelli-de la Forest Divonne, Marie-Christine Etienne-Grimaldi, GÃ©rard Milano, Alexandre Bozec, Emmanuel Babin, Anne Sudaka, Juliette Thariat, Ellen Van Obberghen-Schilling

Published Dec 26, 2014 · Vol. 6, No. 10 · pp. 7570-7583

The anti-HER3 antibody patritumab abrogates cetuximab resistance mediated by heregulin in colorectal cancer cells Research Paper

Hisato Kawakami, Isamu Okamoto, Kimio Yonesaka, Kunio Okamoto, Kiyoko Shibata, Yume Shinkai, Haruka Sakamoto, Michiko Kitano, Takao Tamura, Kazuto Nishio, Kazuhiko Nakagawa

Published Dec 19, 2014 · Vol. 5, No. 23 · pp. 11847-11856

Keywords: colorectal cancer, heregulin, resistance, cetuximab, patritumab

Sema6A and Mical1 control cell growth and survival of BRAF^V600E human melanoma cells Research Paper

Rossella Loria, Giulia Bon, Valentina Perotti, Enzo Gallo, Ilaria Bersani, Paola Baldassari, Manuela Porru, Carlo Leonetti, Selene Di Carlo, Paolo Visca, Maria Felice Brizzi, Andrea Anichini, Roberta Mortarini, Rita Falcioni

Published Dec 18, 2014 · Vol. 6, No. 5 · pp. 2779-2793

A Golgi-based KDELR-dependent signalling pathway controls extracellular matrix degradation Research Paper

Carmen Ruggiero, Giorgia Fragassi, Mauro Grossi, Benedetta Picciani, Rosaria Di Martino, Mirco Capitani, Roberto Buccione, Alberto Luini, Michele Sallese

Published Dec 18, 2014 · Vol. 6, No. 5 · pp. 3375-3393

The T-box transcription factor, TBX3, is a key substrate of AKT3 in melanomagenesis Research Paper

Jade Peres, Shaheen Mowla, Sharon Prince

Published Dec 16, 2014 · Vol. 6, No. 3 · pp. 1821-1833

Keywords: TBX3, AKT3, melanoma, E-cadherin, T-box factors.

Screening analysis of ubiquitin ligases reveals G2E3 as a potential target for chemosensitizing cancer cells Priority Research Paper

Franziska Schmidt, Meike Kunze, Ann-Christine Loock, Matthias Dobbelstein

Published Dec 15, 2014 · Vol. 6, No. 2 · pp. 617-632

Keywords: DNA damage, cisplatin, gemcitabine, siRNA screen, ubiquitin ligase, G2E3, Chk1

Cathelicidin, an antimicrobial peptide produced by macrophages, promotes colon cancer by activating the Wnt/Î²-catenin pathway Research Paper

Dong Li, Wenfan Liu, Xuan Wang, Junlu Wu, Wenqiang Quan, Yiwen Yao, Robert Bals, Shurong Ji, Kaiyin Wu, Jia Guo, Haiying Wan

Published Dec 15, 2014 · Vol. 6, No. 5 · pp. 2939-2950

Afatinib induces apoptosis in NSCLC without EGFR mutation through Elk-1-mediated suppression of CIP2A Research Paper

Ting-Ting Chao, Cheng-Yi Wang, Yen-Lin Chen, Chih-Cheng Lai, Fang-Yu Chang, Yi-Ting Tsai, Chung-Hao H. Chao, Chung-Wai Shiau, Yuh-Chin T. Huang, Chong-Jen Yu, Kuen-Feng Chen

Published Dec 11, 2014 · Vol. 6, No. 4 · pp. 2164-2179

Chloride channel-3 promotes tumor metastasis by regulating membrane ruffling and is associated with poor survival Research Paper

Bin Xu, Xiaobao Jin, Ling Min, Qin Li, Lulu Deng, Hui Wu, Guixian Lin, Lixin Chen, Haifeng Zhang, Chunmei Li, Liwei Wang, Jiayong Zhu, Weizhang Wang, Fujiang Chu, Juan Shen, Hongzhi Li, Jianwen Mao

Published Dec 11, 2014 · Vol. 6, No. 4 · pp. 2434-2450

Co-expression of PKM2 and TRIM35 predicts survival and recurrence in hepatocellular carcinoma Clinical Research Papers

Zhiao Chen, Xinyuan Lu, Zhichao Wang, Guangzhi Jin, Qifeng Wang, Di Chen, Taoyang Chen, Jinjun Li, Jia Fan, Wenming Cong, Qiang Gao, Xianghuo He

Published Dec 11, 2014 · Vol. 6, No. 4 · pp. 2539-2548

Stabilization of LKB1 and Akt by neddylation regulates energy metabolism in liver cancer Research Paper

LucÃa Barbier-Torres, Teresa C. Delgado, Juan L. GarcÃa-RodrÃguez, Imanol Zubiete-Franco, David FernÃ¡ndez-Ramos, Xabier BuquÃ©, Ainara Cano, Virginia GutiÃ©rrez-de Juan, Itziar FernÃ¡ndez-DomÃnguez, Fernando Lopitz-Otsoa, Pablo FernÃ¡ndez-Tussy, Loreto Boix, Jordi Bruix, Erica Villa, Azucena Castro, Shelly C. Lu, Patricia Aspichueta, Dimitris Xirodimas, Marta Varela-Rey, JosÃ© M. Mato, Naiara Beraza, MarÃa L. MartÃnez-Chantar

Published Dec 11, 2014 · Vol. 6, No. 4 · pp. 2509-2523

Phosphorylation of Tip60 by p38Î± regulates p53-mediated PUMA induction and apoptosis in response to DNA damage Priority Research Paper

Yingxi Xu, Rong Liao, Na Li, Rong Xiang, Peiqing Sun

Published Dec 10, 2014 · Vol. 5, No. 24 · pp. 12555-12572

Keywords: p38, Tip60, p53, PUMA, apoptosis

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Acquisition of resistance to trastuzumab in gastric cancer cells is associated with activation of IL-6/STAT3/Jagged-1/Notch positive feedback loop Research Paper

DEPTOR has growth suppression activity against pancreatic cancer cells Research Paper

Autophagy through 4EBP1 and AMPK regulates oxidative stress-induced premature senescence in auditory cells Research Paper

Paracrine SDF-1Î± signaling mediates the effects of PSCs on GEM chemoresistance through an IL-6 autocrine loop in pancreatic cancer cells Research Paper

Tumor promoter-induced cellular senescence: cell cycle arrest followed by geroconversion Research Paper

Metabolic reprogramming of metastatic breast cancer and melanoma by let-7a microRNA Research Paper

Ferroxitosis: A cell death from modulation of oxidative phosphorylation and PKM2-dependent glycolysis in melanoma Research Paper

Expression of the potential therapeutic target CXXC5 in primary acute myeloid leukemia cells - high expression is associated with adverse prognosis as well as altered intracellular signaling and transcriptional regulation Research Paper

Elevated Src family kinase activity stabilizes E-cadherin-based junctions and collective movement of head and neck squamous cell carcinomas Research Paper

The anti-HER3 antibody patritumab abrogates cetuximab resistance mediated by heregulin in colorectal cancer cells Research Paper

Sema6A and Mical1 control cell growth and survival of BRAF^V600E human melanoma cells Research Paper

A Golgi-based KDELR-dependent signalling pathway controls extracellular matrix degradation Research Paper

The T-box transcription factor, TBX3, is a key substrate of AKT3 in melanomagenesis Research Paper

Screening analysis of ubiquitin ligases reveals G2E3 as a potential target for chemosensitizing cancer cells Priority Research Paper

Cathelicidin, an antimicrobial peptide produced by macrophages, promotes colon cancer by activating the Wnt/Î²-catenin pathway Research Paper

Afatinib induces apoptosis in NSCLC without EGFR mutation through Elk-1-mediated suppression of CIP2A Research Paper

Chloride channel-3 promotes tumor metastasis by regulating membrane ruffling and is associated with poor survival Research Paper

Co-expression of PKM2 and TRIM35 predicts survival and recurrence in hepatocellular carcinoma Clinical Research Papers

Stabilization of LKB1 and Akt by neddylation regulates energy metabolism in liver cancer Research Paper

Phosphorylation of Tip60 by p38Î± regulates p53-mediated PUMA induction and apoptosis in response to DNA damage Priority Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Acquisition of resistance to trastuzumab in gastric cancer cells is associated with activation of IL-6/STAT3/Jagged-1/Notch positive feedback loop Research Paper

DEPTOR has growth suppression activity against pancreatic cancer cells Research Paper

Autophagy through 4EBP1 and AMPK regulates oxidative stress-induced premature senescence in auditory cells Research Paper

Paracrine SDF-1Î± signaling mediates the effects of PSCs on GEM chemoresistance through an IL-6 autocrine loop in pancreatic cancer cells Research Paper

Tumor promoter-induced cellular senescence: cell cycle arrest followed by geroconversion Research Paper

Metabolic reprogramming of metastatic breast cancer and melanoma by let-7a microRNA Research Paper

Ferroxitosis: A cell death from modulation of oxidative phosphorylation and PKM2-dependent glycolysis in melanoma Research Paper

Expression of the potential therapeutic target CXXC5 in primary acute myeloid leukemia cells - high expression is associated with adverse prognosis as well as altered intracellular signaling and transcriptional regulation Research Paper

Elevated Src family kinase activity stabilizes E-cadherin-based junctions and collective movement of head and neck squamous cell carcinomas Research Paper

The anti-HER3 antibody patritumab abrogates cetuximab resistance mediated by heregulin in colorectal cancer cells Research Paper

Sema6A and Mical1 control cell growth and survival of BRAFV600E human melanoma cells Research Paper

A Golgi-based KDELR-dependent signalling pathway controls extracellular matrix degradation Research Paper

The T-box transcription factor, TBX3, is a key substrate of AKT3 in melanomagenesis Research Paper

Screening analysis of ubiquitin ligases reveals G2E3 as a potential target for chemosensitizing cancer cells Priority Research Paper

Cathelicidin, an antimicrobial peptide produced by macrophages, promotes colon cancer by activating the Wnt/Î²-catenin pathway Research Paper

Afatinib induces apoptosis in NSCLC without EGFR mutation through Elk-1-mediated suppression of CIP2A Research Paper

Chloride channel-3 promotes tumor metastasis by regulating membrane ruffling and is associated with poor survival Research Paper

Co-expression of PKM2 and TRIM35 predicts survival and recurrence in hepatocellular carcinoma Clinical Research Papers

Stabilization of LKB1 and Akt by neddylation regulates energy metabolism in liver cancer Research Paper

Phosphorylation of Tip60 by p38Î± regulates p53-mediated PUMA induction and apoptosis in response to DNA damage Priority Research Paper

Sema6A and Mical1 control cell growth and survival of BRAF^V600E human melanoma cells Research Paper