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Anticancer effect of physical activity is mediated by modulation of extracellular microRNA in blood Research Paper

Alessandra Pulliero, Ming You, Pradeep Chaluvally-Raghavan, Barbara Marengo, Cinzia Domenicotti, Barbara Banelli, Paolo Degan, Luigi Molfetta, Fabio Gianiorio, Alberto Izzotti

Published May 10, 2020 · Vol. 11, No. 22 · pp. 2106-2119

Keywords: circulating microRNAs, sports and exercise, carcinogenesis, cancer prevention, microRNA transfection

Phase I study of vemurafenib in children with recurrent or progressive BRAF^V600E mutant brain tumors: Pacific Pediatric Neuro-Oncology Consortium study (PNOC-002) Research Paper

Theodore Nicolaides, Kellie J. Nazemi, John Crawford, Lindsay Kilburn, Jane Minturn, Amar Gajjar, Karen Gauvain, Sarah Leary, Girish Dhall, Mariam Aboian, Giles Robinson, Janel Long-Boyle, Hechuan Wang, Annette M. Molinaro, Sabine Mueller, Michael Prados

Published May 5, 2020 · Vol. 11, No. 21 · pp. 1942-1952

Keywords: BRAF^V600E, pediatric glioma, vemurafenib, clinical trial

Hereditary pancreatitis model by blastocyst complementation in mouse Research Paper

Ayumu Asai, Masamitsu Konno, Koichi Kawamoto, Ayako Isotani, Masaki Mori, Hidetoshi Eguchi, Yuichiro Doki, Takahiro Arai, Hideshi Ishii

Published May 2, 2020 · Vol. 11, No. 22 · pp. 2061-2073

Keywords: blastocyst complementation, hereditary pancreatitis, disease-specific pluripotent stem cells, PRSS1

Inhibition of HAS2 and hyaluronic acid production by 1,25-Dihydroxyvitamin D₃ in breast cancer Research Paper

Carmen J. Narvaez, Erika LaPorta, Samantha Robilotto, Jennifer Liang, JoEllen Welsh

Published Apr 25, 2020 · Vol. 11, No. 30 · pp. 2889-2905

Keywords: vitamin D, hyaluronic acid, hyaluronan synthase, HAS2, breast cancer

An exploratory study of metformin with or without rapamycin as maintenance therapy after induction chemotherapy in patients with metastatic pancreatic adenocarcinoma Priority Research Paper

Katherine M. Bever, Erkut H. Borazanci, Elizabeth A. Thompson, Jennifer N. Durham, Kimberly Pinero, Gayle S. Jameson, Amber Vrana, Meizheng Liu, Cara Wilt, Annie A. Wu, Wei Fu, Hao Wang, Yafu Yin, Jeffrey P. Leal, Ana De Jesus-Acosta, Lei Zheng, Daniel A. Laheru, Daniel D. Von Hoff, Elizabeth M. Jaffee, Jonathan D. Powell, Dung T. Le

Published Apr 23, 2020 · Vol. 11, No. 21 · pp. 1929-1941

Keywords: pancreatic cancer, mTOR inhibition, maintenance therapy, metformin

Aberrant epigenetic silencing of neuronatin is a frequent event in human osteosarcoma Research Paper

Haleema Saeed, Sayantani Sinha, Christine Mella, Jeffrey S. Kuerbitz, Monica L. Cales, Mark A. Steele, Jennifer Stanke, Derek Damron, Fayez Safadi, Steven J. Kuerbitz

Published Apr 22, 2020 · Vol. 11, No. 20 · pp. 1876-1893

Keywords: osteosarcoma, DNA methylation, neuronatin, tumor suppressor genes

Aberrant epigenetic silencing of neuronatin is a frequent event in human osteosarcoma Research Paper

Haleema Saeed, Sayantani Sinha, Christine Mella, Jeffrey S. Kuerbitz, Monica L. Cales, Mark A. Steele, Jennifer Stanke, Derek Damron, Fayez Safadi, Steven J. Kuerbitz

Published Apr 22, 2020

Keywords: osteosarcoma, DNA methylation, neuronatin, tumor suppressor genes

Prognostic and predictive factors associated with ipilimumab-related adverse events: a retrospective analysis of 11 NCI-sponsored phase I clinical trials Research Paper

Aman Chauhan, Tanvir Kabir, Jianrong Wu, Jing Wei, Mary Cook, Charles A. Kunos

Published Apr 21, 2020 · Vol. 11, No. 16 · pp. 1427-1434

Keywords: immunotherapy, toxicity, co-administered agents, metastatic melanoma, immune checkpoint inhibitors

Protein phosphatase 1 regulatory subunit 1A regulates cell cycle progression in Ewing sarcoma Research Paper

Wen Luo, Changxin Xu, Sarah Phillips, Aliza Gardenswartz, Jeremy M. Rosenblum, Janet Ayello, Stephen L. Lessnick, Huai-Xiang Hao, Mitchell S. Cairo

Published Apr 16, 2020 · Vol. 11, No. 19 · pp. 1691-1704

Keywords: PPP1R1A, cell cycle control, IGF-1R, metastasis, Ewing sarcoma

A phase II study of axalimogene filolisbac for patients with previously treated, unresectable, persistent/recurrent loco-regional or metastatic anal cancer Research Paper

Cathy Eng, Marwan Fakih, Manik Amin, Van Morris, Howard S. Hochster, Patrick M. Boland, Hope Uronis

Published Apr 14, 2020 · Vol. 11, No. 15 · pp. 1334-1343

Keywords: anal neoplasms, immunotherapy, Listeria monocytogenes, papillomaviridae, phase II clinical trial

Targeted alpha therapy using astatine (²¹¹At)-labeled phenylalanine: A preclinical study in glioma bearing mice Research Paper

Tadashi Watabe, Kazuko Kaneda-Nakashima, Yoshifumi Shirakami, Yuwei Liu, Kazuhiro Ooe, Takahiro Teramoto, Atsushi Toyoshima, Eku Shimosegawa, Takashi Nakano, Yoshikatsu Kanai, Atsushi Shinohara, Jun Hatazawa

Published Apr 14, 2020 · Vol. 11, No. 15 · pp. 1388-1398

Keywords: alpha therapy, astatine, glioma, LAT1, phenylalanine

Proteomic analysis of combined IGF1 receptor targeted therapy and chemotherapy identifies signatures associated with survival in breast cancer patients Research Paper

Tali Sinai-Livne, Metsada Pasmanik-Chor, Zoya Cohen, Ilan Tsarfaty, Haim Werner, Raanan Berger

Published Apr 13, 2020 · Vol. 11, No. 17 · pp. 1515-1530

Keywords: insulin-like growth factor-1 (IGF1), IGF1 receptor (IGF1R), targeted therapy, breast cancer, proteomic analysis

First-in-human study of anticancer immunotherapy drug candidate mobilan: safety, pharmacokinetics and pharmacodynamics in prostate cancer patients Research Paper

Natalia V. Eremina, Vasily I. Kazey, Sergey V. Mishugin, Roman V. Leonenkov, Dmitry Y. Pushkar, Vadim L. Mett, Andrei V. Gudkov

Published Apr 7, 2020 · Vol. 11, No. 14 · pp. 1273-1288

Keywords: prostate cancer, immunotherapy, mobilan, adenoviral vector, intratumor injection

Novel plant microRNAs from broccoletti sprouts do not show cross-kingdom regulation of pancreatic cancer Research Paper

Xi Xiao, Carsten Sticht, Libo Yin, Li Liu, Svetlana Karakhanova, Yefeng Yin, Christina Georgikou, Jury Gladkich, Wolfgang Gross, Norbert Gretz, Ingrid Herr

Published Apr 7, 2020 · Vol. 11, No. 14 · pp. 1203-1217

Keywords: broccoli, broccoletti, Brassica rapa sylvestris, plant microRNAs, cross-kingdom regulation

A phase II randomized clinical trial using aglycone isoflavones to treat patients with localized prostate cancer in the pre-surgical period prior to radical prostatectomy Research Paper

Nagi B. Kumar, Julio Pow-Sang, Philippe Spiess, Shohreh Dickinson, Michael J. Schell

Published Apr 7, 2020 · Vol. 11, No. 14 · pp. 1218-1234

Keywords: isoflavones, chemoprevention, prostate cancer, African American men, Caucasian men

A mutation-specific, single-arm, phase 2 study of dovitinib in patients with advanced malignancies Research Paper

Matthew H. Taylor, Ajjai S. Alva, Timothy Larson, Sebastian Szpakowski, Das Purkaystha, Alpesh Amin, Linda Karpiak, Sarina A. Piha-Paul

Published Apr 7, 2020 · Vol. 11, No. 14 · pp. 1235-1243

Keywords: advanced malignancies, basket trial, dovitinib, histology-agnostic, mutation-specific

Quinacrine inhibits GSTA1 activity and induces apoptosis through G₁/S arrest and generation of ROS in human non-small cell lung cancer cell lines Research Paper

Makhan Kumar, Ansie Martin, Snehal Nirgude, Bibha Chaudhary, Sukanta Mondal, Angshuman Sarkar

Published Apr 6, 2020 · Vol. 11, No. 18 · pp. 1603-1617

Keywords: quinacrine, NSCLC, RhoGTPases, apoptosis, cell cycle

Transcriptional regulation of HSPB1 by Friend leukemia integration-1 factor modulates radiation and temozolomide resistance in glioblastoma Priority Research Paper

Yetirajam Rajesh, Angana Biswas, Payel Banik, Ipsita Pal, Subhayan Das, Sachin A. Borkar, Hardik Sardana, Abhijit Saha, Swadesh K. Das, Luni Emdad, Paul B. Fisher, Mahitosh Mandal

Published Mar 31, 2020 · Vol. 11, No. 13 · pp. 1097-1108

Keywords: HSPB1, RNAseq, Fli-1, radioresistant GBM, temozolomide resistant GBM

Synergistic cytotoxic activity of cannabinoids from cannabis sativa against cutaneous T-cell lymphoma (CTCL) in-vitro and ex-vivo Research Paper

Moran Mazuz, Amir Tiroler, Lilach Moyal, Emmilia Hodak, Stalin Nadarajan, Ajjampura C. Vinayaka, Batia Gorovitz-Haris, Ido Lubin, Avi Drori, Guy Drori, Owen Van Cauwenberghe, Adi Faigenboim, Dvora Namdar, Iris Amitay-Laish, Hinanit Koltai

Published Mar 31, 2020 · Vol. 11, No. 13 · pp. 1141-1156

Keywords: cutaneous T-cell lymphoma, cannabis, cannabinoids, peripheral blood lymphocytes, CTCL cell lines

Correction: Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes Correction

Faruck L. Hakkim, Hamid A. Bakshi, Shabia Khan, Mohamed M. Nasef, Rabia Farzand, Smitha Sam, Luay Rashan, Mohammed S. Al-Baloshi, Sidgi Syed Anwar Abdo Hasson, Ali Al Jabri, Paul A. McCarron, Murtaza M. Tambuwala

Published Mar 23, 2020 · Vol. 11, No. 23 · pp. 2259-2261

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Anticancer effect of physical activity is mediated by modulation of extracellular microRNA in blood Research Paper

Phase I study of vemurafenib in children with recurrent or progressive BRAF^V600E mutant brain tumors: Pacific Pediatric Neuro-Oncology Consortium study (PNOC-002) Research Paper

Hereditary pancreatitis model by blastocyst complementation in mouse Research Paper

Inhibition of HAS2 and hyaluronic acid production by 1,25-Dihydroxyvitamin D₃ in breast cancer Research Paper

An exploratory study of metformin with or without rapamycin as maintenance therapy after induction chemotherapy in patients with metastatic pancreatic adenocarcinoma Priority Research Paper

Aberrant epigenetic silencing of neuronatin is a frequent event in human osteosarcoma Research Paper

Aberrant epigenetic silencing of neuronatin is a frequent event in human osteosarcoma Research Paper

Prognostic and predictive factors associated with ipilimumab-related adverse events: a retrospective analysis of 11 NCI-sponsored phase I clinical trials Research Paper

Protein phosphatase 1 regulatory subunit 1A regulates cell cycle progression in Ewing sarcoma Research Paper

A phase II study of axalimogene filolisbac for patients with previously treated, unresectable, persistent/recurrent loco-regional or metastatic anal cancer Research Paper

Targeted alpha therapy using astatine (²¹¹At)-labeled phenylalanine: A preclinical study in glioma bearing mice Research Paper

Proteomic analysis of combined IGF1 receptor targeted therapy and chemotherapy identifies signatures associated with survival in breast cancer patients Research Paper

First-in-human study of anticancer immunotherapy drug candidate mobilan: safety, pharmacokinetics and pharmacodynamics in prostate cancer patients Research Paper

Novel plant microRNAs from broccoletti sprouts do not show cross-kingdom regulation of pancreatic cancer Research Paper

A phase II randomized clinical trial using aglycone isoflavones to treat patients with localized prostate cancer in the pre-surgical period prior to radical prostatectomy Research Paper

A mutation-specific, single-arm, phase 2 study of dovitinib in patients with advanced malignancies Research Paper

Quinacrine inhibits GSTA1 activity and induces apoptosis through G₁/S arrest and generation of ROS in human non-small cell lung cancer cell lines Research Paper

Transcriptional regulation of HSPB1 by Friend leukemia integration-1 factor modulates radiation and temozolomide resistance in glioblastoma Priority Research Paper

Synergistic cytotoxic activity of cannabinoids from cannabis sativa against cutaneous T-cell lymphoma (CTCL) in-vitro and ex-vivo Research Paper

Correction: Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes Correction

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Anticancer effect of physical activity is mediated by modulation of extracellular microRNA in blood Research Paper

Phase I study of vemurafenib in children with recurrent or progressive BRAFV600E mutant brain tumors: Pacific Pediatric Neuro-Oncology Consortium study (PNOC-002) Research Paper

Hereditary pancreatitis model by blastocyst complementation in mouse Research Paper

Inhibition of HAS2 and hyaluronic acid production by 1,25-Dihydroxyvitamin D3 in breast cancer Research Paper

An exploratory study of metformin with or without rapamycin as maintenance therapy after induction chemotherapy in patients with metastatic pancreatic adenocarcinoma Priority Research Paper

Aberrant epigenetic silencing of neuronatin is a frequent event in human osteosarcoma Research Paper

Aberrant epigenetic silencing of neuronatin is a frequent event in human osteosarcoma Research Paper

Prognostic and predictive factors associated with ipilimumab-related adverse events: a retrospective analysis of 11 NCI-sponsored phase I clinical trials Research Paper

Protein phosphatase 1 regulatory subunit 1A regulates cell cycle progression in Ewing sarcoma Research Paper

A phase II study of axalimogene filolisbac for patients with previously treated, unresectable, persistent/recurrent loco-regional or metastatic anal cancer Research Paper

Targeted alpha therapy using astatine (211At)-labeled phenylalanine: A preclinical study in glioma bearing mice Research Paper

Proteomic analysis of combined IGF1 receptor targeted therapy and chemotherapy identifies signatures associated with survival in breast cancer patients Research Paper

First-in-human study of anticancer immunotherapy drug candidate mobilan: safety, pharmacokinetics and pharmacodynamics in prostate cancer patients Research Paper

Novel plant microRNAs from broccoletti sprouts do not show cross-kingdom regulation of pancreatic cancer Research Paper

A phase II randomized clinical trial using aglycone isoflavones to treat patients with localized prostate cancer in the pre-surgical period prior to radical prostatectomy Research Paper

A mutation-specific, single-arm, phase 2 study of dovitinib in patients with advanced malignancies Research Paper

Quinacrine inhibits GSTA1 activity and induces apoptosis through G1/S arrest and generation of ROS in human non-small cell lung cancer cell lines Research Paper

Transcriptional regulation of HSPB1 by Friend leukemia integration-1 factor modulates radiation and temozolomide resistance in glioblastoma Priority Research Paper

Synergistic cytotoxic activity of cannabinoids from cannabis sativa against cutaneous T-cell lymphoma (CTCL) in-vitro and ex-vivo Research Paper

Correction: Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes Correction

Phase I study of vemurafenib in children with recurrent or progressive BRAF^V600E mutant brain tumors: Pacific Pediatric Neuro-Oncology Consortium study (PNOC-002) Research Paper

Inhibition of HAS2 and hyaluronic acid production by 1,25-Dihydroxyvitamin D₃ in breast cancer Research Paper

Targeted alpha therapy using astatine (²¹¹At)-labeled phenylalanine: A preclinical study in glioma bearing mice Research Paper

Quinacrine inhibits GSTA1 activity and induces apoptosis through G₁/S arrest and generation of ROS in human non-small cell lung cancer cell lines Research Paper