The Oncosearch | Oncotarget

A novel curcumin analog inhibits canonical and non-canonical functions of telomerase through STAT3 and NF-κB inactivation in colorectal cancer cells Research Paper

Seyung S. Chung, Pranabananda Dutta, Nathaniel Chard, Yong Wu, Qiao-Hong Chen, Guanglin Chen, Jaydutt Vadgama

Published Jul 16, 2019 · Vol. 10, No. 44 · pp. 4516-4531

Keywords: curcumin analog, cancer stem cells, colorectal cancer, STAT3, NF-κB

Transglutaminase 2 maintains a colorectal cancer stem phenotype by regulating epithelial-mesenchymal transition Research Paper

Oluseyi Ayinde, Zhuo Wang, Giulia Pinton, Laura Moro, Martin Griffin

Published Jul 16, 2019 · Vol. 10, No. 44 · pp. 4556-4569

Keywords: transglutaminase 2, colorectal cancer, epithelial-mesenchymal transition, cancer Stem Cells, β-catenin

Dicer prevents genome instability in response to replication stress Research Paper

Michalis Fragkos, Viviana Barra, Tom Egger, Benoit Bordignon, Delphine Lemacon, Valeria Naim, Arnaud Coquelle

Published Jul 9, 2019 · Vol. 10, No. 43 · pp. 4407-4423

Keywords: replication stress, common fragile sites, Dicer, genomic instability

Modified Simon’s minimax and optimal two-stage designs for single-arm phase II cancer clinical trials Research Paper

Jongphil Kim, Michael J. Schell

Published Jul 2, 2019 · Vol. 10, No. 42 · pp. 4255-4261

Keywords: admissible two-stage design, binary endpoint, modified two-stage design, Simon’s two-stage design, single-arm phase ii clinical trials

Comparative RNA-seq analysis reveals dys-regulation of major canonical pathways in ERG-inducible LNCaP cell progression model of prostate cancer Research Paper

Parameet Kumar, Joyeeta Chakraborty, Gauthaman Sukumar, Clifton Dalgard, Raghunath Chatterjee, Roopa Biswas

Published Jul 2, 2019 · Vol. 10, No. 42 · pp. 4290-4306

Keywords: RNAseq, prostate cancer, LNCaP cells, ERG, mRNA

Risk of venous and arterial thromboembolic events associated with tyrosine kinase inhibitors in advanced thyroid cancer: a meta-analysis and systematic review Meta-Analysis

Yang Bai, Jing-Yan Li, Jie Li, Bo Zhang, Yong-Hong Liu, Bu-Yong Zhang, Jian Jing

Published Jun 25, 2019 · Vol. 10, No. 41 · pp. 4205-4212

Real-world experience with cabazitaxel in patients with metastatic castration-resistant prostate cancer: a final, pooled analysis of the compassionate use programme and early access programme Research Paper

Zafar Malik, Axel Heidenreich, Sergio Bracarda, Alexandros Ardavanis, Philip Parente, Hans-Joerg Scholz, Ayse Ozatilgan, Evelyne Ecstein-Fraisse, Simon Hitier, Giuseppe Di Lorenzo

Published Jun 25, 2019 · Vol. 10, No. 41 · pp. 4161-4168

Keywords: mCRPC, cabazitaxel, CUP, EAP, real-world

Dicer prevents genome instability in response to replication stress Research Paper

Michalis Fragkos, Viviana Barra, Tom Egger, Benoit Bordignon, Delphine Lemacon, Valeria Naim, Arnaud Coquelle

Published Jun 11, 2019

Keywords: replication stress, common fragile sites, Dicer, genomic instability

Dicer prevents genome instability in response to replication stress Research Paper

Michalis Fragkos, Viviana Barra, Tom Egger, Benoit Bordignon, Delphine Lemacon, Valeria Naim, Arnaud Coquelle

Published Jun 11, 2019

Keywords: replication stress, common fragile sites, Dicer, genomic instability

Investigating the role of LSD2 as an epigenetic regulator in Ewing sarcoma Research Paper

Priyal O. Patel, Kathleen I. Pishas, Cenny Taslim, Julia Selich-Anderson, Emily R. Theisen, Stephen L. Lessnick

Published Jun 11, 2019 · Vol. 10, No. 39 · pp. 3865-3878

Keywords: LSD2/KDM1B, Ewing sarcoma, SP-2509, LSD1/KDM1A

Plasma lncRNA expression profile as a prognostic tool in BRAF-mutant metastatic melanoma patients treated with BRAF inhibitor Research Paper

Tomasz Kolenda, Piotr Rutkowski, Michał Michalak, Katarzyna Kozak, Kacper Guglas, Marcel Ryś, Łukasz Galus, Sebastian Woźniak, Iwona Ługowska, Aleksandra Gos, Anna Teresiak, Andrzej Mackiewicz, Katarzyna Lamperska, Jacek Mackiewicz

Published Jun 11, 2019 · Vol. 10, No. 39 · pp. 3879-3893

Keywords: melanoma, BRAF mutation, BRAF inhibitor, lncRNA, liquid biopsy

Correction: First-in-human phase 1 study of the BTK inhibitor GDC-0853 in relapsed or refractory B-cell NHL and CLL Correction

John C. Byrd, Stephen Smith, Nina Wagner-Johnston, Jeff Sharman, Andy I. Chen, Ranjana Advani, Bradley Augustson, Paula Marlton, S. Renee Commerford, Kwame Okrah, Lichuan Liu, Elaine Murray, Elicia Penuel, Ashley F. Ward, Ian W. Flinn

Published May 30, 2019 · Vol. 10, No. 38 · pp. 3827-3830

Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes Research Paper

Faruck L. Hakkim, Hamid A. Bakshi, Shabia Khan, Mohamad Nasef, Rabia Farzand, Smitha Sam, Luay Rashan, Mohammed S. Al-Baloshi, Sidgi Syed Anwar Abdo Hasson, Ali Al Jabri, Paul A. McCarron, Murtaza M. Tambuwala

Published May 28, 2019 · Vol. 10, No. 37 · pp. 3472-3490

Keywords: melanoma, frankincense, essential oil, apoptosis, tumor remission

Constitutive activation of EGFR is associated with tumor progression and plays a prominent role in malignant phenotype of chondrosarcoma Research Paper

Jun Qin, Irfan Shaukat, Didier Mainard, Patrick Netter, Lydia Barré, Mohamed Ouzzine

Published May 7, 2019 · Vol. 10, No. 34 · pp. 3166-3182

Keywords: chondrosarcoma, EGF/EGFR signaling, biomarker, tyrosine kinase inhibitor, cell death

Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes Research Paper

Faruck L. Hakkim, Hamid A. Bakshi, Shabia Khan, Mohamad Nasef, Rabia Farzand, Smitha Sam, Luay Rashan, Al-Balushi MS, Hasson SS, Ali Al Jabri, Paul A McCarron, Murtaza M Tambuwala

Published May 3, 2019

Keywords: melanoma, frankincense, essential oil, apoptosis, tumor remission

Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes Research Paper

Faruck L. Hakkim, Hamid A. Bakshi, Shabia Khan, Mohamad Nasef, Rabia Farzand, Smitha Sam, Luay Rashan, Al-Balushi MS, Hasson SS, Ali Al Jabri, Paul A McCarron, Murtaza M Tambuwala

Published May 3, 2019

Keywords: melanoma, frankincense, essential oil, apoptosis, tumor remission

Phase I study of local radiation and tremelimumab in patients with inoperable locally recurrent or metastatic breast cancer Research Paper

Di (Maria) Jiang, Anthony Fyles, Linh T. Nguyen, Benjamin G. Neel, Adrian Sacher, Robert Rottapel, Ben X. Wang, Pamela S. Ohashi, Srikala S. Sridhar

Published Apr 26, 2019 · Vol. 10, No. 31 · pp. 2947-2958

Keywords: radiation, immunotherapy, breast cancer, anti-CTLA-4

Phase I/Ib study of olaparib and carboplatin in heavily pretreated recurrent high-grade serous ovarian cancer at low genetic risk Research Paper

Erika J. Lampert, John L. Hays, Elise C. Kohn, Christina M. Annunziata, Lori Minasian, Minshu Yu, Nicolas Gordon, Tristan M. Sissung, Victoria L. Chiou, William D. Figg, Nicole Houston, Jung-Min Lee

Published Apr 23, 2019 · Vol. 10, No. 30 · pp. 2855-2868

Keywords: high-grade serous ovarian cancer, BRCA wild type, olaparib, carboplatin

Axl signaling is an important mediator of tumor angiogenesis Research Paper

Mai Tanaka, Dietmar W. Siemann

Published Apr 23, 2019 · Vol. 10, No. 30 · pp. 2887-2898

Keywords: Axl, angiogenesis, cancer metastasis, BGB324, receptor tyrosine kinase

You BETer be aware â€“ learnings from a negative Phase 1 study Editorial

Sophie Postel-Vinay, Matthias Ocker

Published Apr 18, 2019 · Vol. 10, No. 34 · pp. 3145-3146

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

A novel curcumin analog inhibits canonical and non-canonical functions of telomerase through STAT3 and NF-κB inactivation in colorectal cancer cells Research Paper

Transglutaminase 2 maintains a colorectal cancer stem phenotype by regulating epithelial-mesenchymal transition Research Paper

Dicer prevents genome instability in response to replication stress Research Paper

Modified Simon’s minimax and optimal two-stage designs for single-arm phase II cancer clinical trials Research Paper

Comparative RNA-seq analysis reveals dys-regulation of major canonical pathways in ERG-inducible LNCaP cell progression model of prostate cancer Research Paper

Risk of venous and arterial thromboembolic events associated with tyrosine kinase inhibitors in advanced thyroid cancer: a meta-analysis and systematic review Meta-Analysis

Real-world experience with cabazitaxel in patients with metastatic castration-resistant prostate cancer: a final, pooled analysis of the compassionate use programme and early access programme Research Paper

Dicer prevents genome instability in response to replication stress Research Paper

Dicer prevents genome instability in response to replication stress Research Paper

Investigating the role of LSD2 as an epigenetic regulator in Ewing sarcoma Research Paper

Plasma lncRNA expression profile as a prognostic tool in BRAF-mutant metastatic melanoma patients treated with BRAF inhibitor Research Paper

Correction: First-in-human phase 1 study of the BTK inhibitor GDC-0853 in relapsed or refractory B-cell NHL and CLL Correction

Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes Research Paper

Constitutive activation of EGFR is associated with tumor progression and plays a prominent role in malignant phenotype of chondrosarcoma Research Paper

Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes Research Paper

Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes Research Paper

Phase I study of local radiation and tremelimumab in patients with inoperable locally recurrent or metastatic breast cancer Research Paper

Phase I/Ib study of olaparib and carboplatin in heavily pretreated recurrent high-grade serous ovarian cancer at low genetic risk Research Paper

Axl signaling is an important mediator of tumor angiogenesis Research Paper

You BETer be aware â€“ learnings from a negative Phase 1 study Editorial

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

A novel curcumin analog inhibits canonical and non-canonical functions of telomerase through STAT3 and NF-κB inactivation in colorectal cancer cells Research Paper

Transglutaminase 2 maintains a colorectal cancer stem phenotype by regulating epithelial-mesenchymal transition Research Paper

Dicer prevents genome instability in response to replication stress Research Paper

Modified Simon’s minimax and optimal two-stage designs for single-arm phase II cancer clinical trials Research Paper

Comparative RNA-seq analysis reveals dys-regulation of major canonical pathways in ERG-inducible LNCaP cell progression model of prostate cancer Research Paper

Risk of venous and arterial thromboembolic events associated with tyrosine kinase inhibitors in advanced thyroid cancer: a meta-analysis and systematic review Meta-Analysis

Real-world experience with cabazitaxel in patients with metastatic castration-resistant prostate cancer: a final, pooled analysis of the compassionate use programme and early access programme Research Paper

Dicer prevents genome instability in response to replication stress Research Paper

Dicer prevents genome instability in response to replication stress Research Paper

Investigating the role of LSD2 as an epigenetic regulator in Ewing sarcoma Research Paper

Plasma lncRNA expression profile as a prognostic tool in BRAF-mutant metastatic melanoma patients treated with BRAF inhibitor Research Paper

Correction: First-in-human phase 1 study of the BTK inhibitor GDC-0853 in relapsed or refractory B-cell NHL and CLL Correction

Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes Research Paper

Constitutive activation of EGFR is associated with tumor progression and plays a prominent role in malignant phenotype of chondrosarcoma Research Paper

Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes Research Paper

Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes Research Paper

Phase I study of local radiation and tremelimumab in patients with inoperable locally recurrent or metastatic breast cancer Research Paper

Phase I/Ib study of olaparib and carboplatin in heavily pretreated recurrent high-grade serous ovarian cancer at low genetic risk Research Paper

Axl signaling is an important mediator of tumor angiogenesis Research Paper

You BETer be aware â€“ learnings from a negative Phase 1 study Editorial