The Oncosearch | Oncotarget

COVID vaccination and post-infection cancer signals: Evaluating patterns and potential biological mechanisms Review

Charlotte Kuperwasser, Wafik S. El-Deiry

Published Mar 30, 2026 · Vol. 17, No. 1 · pp. 1-29

Keywords: COVID, vaccine, cancer, infection, lymphoma, leukemia, sarcoma, carcinoma

Nerofe+ldDox releases c-Jun from nuclear ST2 to reprogram the immune microenvironment in mtKRAS tumors Research Paper

Joel Ohana, Uziel Sandler, Benjamin A. Weinberg, Stephen Liu, Yoram Devary

Published Dec 19, 2025 · Vol. 16, No. 1 · pp. 848-857

Keywords: mutant KRAS, Nerofe, ST2 Receptor, tumor immune microenvironment, nuclear immunomodulation

A personal perspective of patient-centred clinical trials Research Perspective

Trevor Tyne, Elizabeth Ivimey, Leanne Duggan, Jia Liu

Published Nov 5, 2025 · Vol. 16, No. 1 · pp. 808-812

Keywords: precision oncology, patient-centric care, clinical trials, tumor agnostic, drug development

Statins exhibit anti-tumor potential by modulating Wnt/β-catenin signaling in colorectal cancer Research Paper

Sneha Tripathi, Ekta Gupta, Rutika Naik, Satyajeet Khare, Rafeeq Mir, Siddhesh Kamat, Sanjeev Galande

Published Jul 12, 2025 · Vol. 16, No. 1 · pp. 562-581

Keywords: colorectal cancer, statins, SATB1, Wnt/β-catenin signaling, tumor-suppressive phenotype

Exceptional responders to immunotherapy in pancreatic cancer: A multi-institutional case series of a rare occurrence Research Paper

Kavin Sugumar, Andrew Alabd, Andre Alabd, Jonathan J. Hue, Josh Lyons, Sherri Fields, Zev Wainberg, Lei Zheng, Brianna Coogle, Anup Kasi, Nicholas Grewal, Hedy L. Kindler, Jason Starr, Ashwin R. Sama, Jordan M. Winter

Published Jun 3, 2025 · Vol. 16, No. 1 · pp. 427-442

Keywords: pancreatic adenocarcinoma, immunotherapy, exceptional responders, microsatellite instability, survival

Imipridones ONC201/ONC206 + RT/TMZ triple (IRT) therapy reduces intracranial tumor burden, prolongs survival in orthotopic IDH-WT GBM mouse model, and suppresses MGMT Research Paper

Lanlan Zhou, Leiqing Zhang, Jun Zhang, Laura Jinxuan Wu, Shengliang Zhang, Andrew George, Marina Hahn, Howard P. Safran, Clark C. Chen, Attila A. Seyhan, Eric T. Wong, Wafik S. El-Deiry

Published Mar 20, 2025 · Vol. 16, No. 1 · pp. 230-248

Keywords: glioblastoma multiforme, IDH, ONC201, ONC206, MGMT, temozolomide, radiotherapy

Leukopenia, weight loss and oral mucositis induced by 5-Fluorouracil in hamsters’ model: A regenerative approach using electrospun poly(Lactic-co-Glycolic Acid) membrane Research Paper

Ana Chor, Hélio dos Santos Dutra, Marcos Lopes Dias, Raquel Pires Gonçalves, Alexandre Malta Rossi, Christina Maeda Takiya, Marcos Farina

Published Jan 22, 2025 · Vol. 16, No. 1 · pp. 103-117

Keywords: leukopenia, weight loss, oral mucositis, PLGA dressing, regeneration

A case of adenosquamous pancreatic cancer with a KRAS G12C mutation with an exceptional response to immunotherapy Case Report

Murtaza Ahmed, Brent K. Larson, Arsen Osipov, Nilofer Azad, Andrew Hendifar

Published Oct 3, 2024 · Vol. 15, No. 1 · pp. 741-747

Keywords: pancreatic cancer, immunotherapy, metastasis

Improved efficacy of pembrolizumab combined with soluble EphB4-albumin in HPV-negative EphrinB2 positive head neck squamous cell carcinoma Research Paper

Alexandra Jackovich, Barbara J. Gitlitz, Justin Wayne Wong Tiu-lim, Vinay Duddalwar, Kevin George King, Anthony B. El-Khoueiry, Jacob Stephen Thomas, Denice Tsao-Wei, David I. Quinn, Parkash S. Gill, Jorge J. Nieva

Published Jun 29, 2024 · Vol. 15, No. 1 · pp. 444-458

Keywords: EphrinB2, EphB4, HNSCC, pembrolizumab, HPV-negative

GZ17-6.02 kills PDX isolates of uveal melanoma Research Paper

Laurence Booth, Jane L. Roberts, Ivan Spasojevic, Kaitlyn C. Baker, Andrew Poklepovic, Cameron West, John M. Kirkwood, Paul Dent

Published May 9, 2024 · Vol. 15, No. 1 · pp. 328-344

Keywords: autophagy, ER stress, GZ17-6.02, doxorubicin, afatinib, neratinib

GZ17-6.02 interacts with proteasome inhibitors to kill multiple myeloma cells Research Paper

Laurence Booth, Jane L. Roberts, Cameron West, Paul Dent

Published Jan 29, 2024 · Vol. 15, No. 1 · pp. 159-174

Keywords: autophagy, ER stress, GZ17-6.02, bortezomib, proteasome inhibitor

GZ17-6.02 interacts with bexarotene to kill mycosis fungoides cells Research Paper

Michael R. Booth, Laurence Booth, Jane L. Roberts, Cameron West, Paul Dent

Published Jan 29, 2024 · Vol. 15, No. 1 · pp. 124-133

Keywords: autophagy, ER stress, GZ17-6.02, bexarotene, vorinostat

ATR inhibition using gartisertib enhances cell death and synergises with temozolomide and radiation in patient-derived glioblastoma cell lines Research Paper

Mathew Lozinski, Nikola A. Bowden, Moira C. Graves, Michael Fay, Bryan W. Day, Brett W. Stringer, Paul A. Tooney

Published Jan 5, 2024 · Vol. 15, No. 1 · pp. 1-18

Keywords: glioblastoma, DNA damage response, ataxia-telangiectasia and rad3-related protein, radiation therapy, temozolomide

Combining causal and correlative approaches to discover biomarkers of response to paclitaxel Research Perspective

Alberto Moscona-Nissan, Karl J. Habashy, Victor A. Arrieta, Adam M. Sonabend, Crismita Dmello

Published Jan 2, 2024 · Vol. 15, No. 1 · pp. 117-122

Keywords: glioblastoma, predictive biomarker, CRISPR screen, paclitaxel

Correction: MicroRNA 603 acts as a tumor suppressor and inhibits triple-negative breast cancer tumorigenesis by targeting elongation factor 2 kinase Correction

Recep Bayraktar, Martin Pichler, Pinar Kanlikilicer, Cristina Ivan, Emine Bayraktar, Nermin Kahraman, Burcu Aslan, Serpil Oguztuzun, Mustafa Ulasli, Ahmet Arslan, George Calin, Gabriel Lopez-Berestein, Bulent Ozpolat

Published Oct 26, 2023 · Vol. 14, No. 1 · pp. 908-909

Correction: Utilizing metformin to prevent metabolic syndrome due to androgen deprivation therapy (ADT): a randomized phase II study of metformin in non-diabetic men initiating ADT for advanced prostate cancer Correction

Devalingam Mahalingam, Salih Hanni, Anthony V. Serritella, Christos Fountzilas, Joel Michalek, Brian Hernandez, John Sarantopoulos, Paromitta Datta, Ofelia Romero, Sureshkumar Mulampurath Achutan Pillai, John Kuhn, Michael Pollak, Ian M. Thompson

Published Oct 13, 2023 · Vol. 14, No. 1 · pp. 890-892

Inhibiting BRAF/EGFR/MEK suppresses cancer stemness and drug resistance of primary colorectal cancer cells Research Paper

Astha Lamichhane, Gary D. Luker, Seema Agarwal, Hossein Tavana

Published Sep 25, 2023 · Vol. 14, No. 1 · pp. 879-889

Keywords: drug resistance, cancer stem cells, patient-derived tumor model, colorectal cancer, combination treatment

Diphenyl ditelluride anticancer activity and DNA topoisomerase I poisoning in human colon cancer HCT116 cells Research Paper

André Luiz Mendes Juchem, Cristiano Trindade, Juliana Bondan da Silva, Miriana da Silva Machado, Temenouga Nikolova Guecheva, Jaqueline Cesar Rocha, Jenifer Saffi, Iuri Marques de Oliveira, João Antonio Pêgas Henriques, Alexandre Escargueil

Published Jun 16, 2023 · Vol. 14, No. 1 · pp. 637-649

Keywords: colorectal cancer, HCT116, diphenyl ditelluride, organotellurium, topoisomerase I

Utilizing metformin to prevent metabolic syndrome due to androgen deprivation therapy (ADT): a randomized phase II study of metformin in non-diabetic men initiating ADT for advanced prostate cancer Research Paper

Devalingam Mahalingam, Salih Hanni, Anthony V. Serritella, Christos Fountzilas, Joel Michalek, Brian Hernandez, John Sarantopoulos, Paromitta Datta, Ofelia Romero, Sureshkumar Mulampurath Achutan Pillai, John Kuhn, Michael Pollak, Ian M. Thompson

Published Jun 8, 2023 · Vol. 14, No. 1 · pp. 622-636

Keywords: prostate cancer, metformin, metastatic, androgen deprivation therapy, clinical trial

G-protein-coupled receptor 141 mediates breast cancer proliferation and metastasis by regulating oncogenic mediators and the p-mTOR/p53 axis Research Paper

Monalisa Parija, Amit K. Adhya, Sandip K. Mishra

Published May 11, 2023 · Vol. 14, No. 1 · pp. 466-480

Keywords: G-protein-coupled receptor 141, cell migration, metastasis, p-mTOR, p53

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

COVID vaccination and post-infection cancer signals: Evaluating patterns and potential biological mechanisms Review

Nerofe+ldDox releases c-Jun from nuclear ST2 to reprogram the immune microenvironment in mtKRAS tumors Research Paper

A personal perspective of patient-centred clinical trials Research Perspective

Statins exhibit anti-tumor potential by modulating Wnt/β-catenin signaling in colorectal cancer Research Paper

Exceptional responders to immunotherapy in pancreatic cancer: A multi-institutional case series of a rare occurrence Research Paper

Imipridones ONC201/ONC206 + RT/TMZ triple (IRT) therapy reduces intracranial tumor burden, prolongs survival in orthotopic IDH-WT GBM mouse model, and suppresses MGMT Research Paper

Leukopenia, weight loss and oral mucositis induced by 5-Fluorouracil in hamsters’ model: A regenerative approach using electrospun poly(Lactic-co-Glycolic Acid) membrane Research Paper

A case of adenosquamous pancreatic cancer with a KRAS G12C mutation with an exceptional response to immunotherapy Case Report

Improved efficacy of pembrolizumab combined with soluble EphB4-albumin in HPV-negative EphrinB2 positive head neck squamous cell carcinoma Research Paper

GZ17-6.02 kills PDX isolates of uveal melanoma Research Paper

GZ17-6.02 interacts with proteasome inhibitors to kill multiple myeloma cells Research Paper

GZ17-6.02 interacts with bexarotene to kill mycosis fungoides cells Research Paper

ATR inhibition using gartisertib enhances cell death and synergises with temozolomide and radiation in patient-derived glioblastoma cell lines Research Paper

Combining causal and correlative approaches to discover biomarkers of response to paclitaxel Research Perspective

Correction: MicroRNA 603 acts as a tumor suppressor and inhibits triple-negative breast cancer tumorigenesis by targeting elongation factor 2 kinase Correction

Correction: Utilizing metformin to prevent metabolic syndrome due to androgen deprivation therapy (ADT): a randomized phase II study of metformin in non-diabetic men initiating ADT for advanced prostate cancer Correction

Inhibiting BRAF/EGFR/MEK suppresses cancer stemness and drug resistance of primary colorectal cancer cells Research Paper

Diphenyl ditelluride anticancer activity and DNA topoisomerase I poisoning in human colon cancer HCT116 cells Research Paper

Utilizing metformin to prevent metabolic syndrome due to androgen deprivation therapy (ADT): a randomized phase II study of metformin in non-diabetic men initiating ADT for advanced prostate cancer Research Paper

G-protein-coupled receptor 141 mediates breast cancer proliferation and metastasis by regulating oncogenic mediators and the p-mTOR/p53 axis Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

COVID vaccination and post-infection cancer signals: Evaluating patterns and potential biological mechanisms Review

Nerofe+ldDox releases c-Jun from nuclear ST2 to reprogram the immune microenvironment in mtKRAS tumors Research Paper

A personal perspective of patient-centred clinical trials Research Perspective

Statins exhibit anti-tumor potential by modulating Wnt/β-catenin signaling in colorectal cancer Research Paper

Exceptional responders to immunotherapy in pancreatic cancer: A multi-institutional case series of a rare occurrence Research Paper

Imipridones ONC201/ONC206 + RT/TMZ triple (IRT) therapy reduces intracranial tumor burden, prolongs survival in orthotopic IDH-WT GBM mouse model, and suppresses MGMT Research Paper

Leukopenia, weight loss and oral mucositis induced by 5-Fluorouracil in hamsters’ model: A regenerative approach using electrospun poly(Lactic-co-Glycolic Acid) membrane Research Paper

A case of adenosquamous pancreatic cancer with a KRAS G12C mutation with an exceptional response to immunotherapy Case Report

Improved efficacy of pembrolizumab combined with soluble EphB4-albumin in HPV-negative EphrinB2 positive head neck squamous cell carcinoma Research Paper

GZ17-6.02 kills PDX isolates of uveal melanoma Research Paper

GZ17-6.02 interacts with proteasome inhibitors to kill multiple myeloma cells Research Paper

GZ17-6.02 interacts with bexarotene to kill mycosis fungoides cells Research Paper

ATR inhibition using gartisertib enhances cell death and synergises with temozolomide and radiation in patient-derived glioblastoma cell lines Research Paper

Combining causal and correlative approaches to discover biomarkers of response to paclitaxel Research Perspective

Correction: MicroRNA 603 acts as a tumor suppressor and inhibits triple-negative breast cancer tumorigenesis by targeting elongation factor 2 kinase Correction

Correction: Utilizing metformin to prevent metabolic syndrome due to androgen deprivation therapy (ADT): a randomized phase II study of metformin in non-diabetic men initiating ADT for advanced prostate cancer Correction

Inhibiting BRAF/EGFR/MEK suppresses cancer stemness and drug resistance of primary colorectal cancer cells Research Paper

Diphenyl ditelluride anticancer activity and DNA topoisomerase I poisoning in human colon cancer HCT116 cells Research Paper

Utilizing metformin to prevent metabolic syndrome due to androgen deprivation therapy (ADT): a randomized phase II study of metformin in non-diabetic men initiating ADT for advanced prostate cancer Research Paper

G-protein-coupled receptor 141 mediates breast cancer proliferation and metastasis by regulating oncogenic mediators and the p-mTOR/p53 axis Research Paper