The Oncosearch | Oncotarget

ATR inhibition reverses the resistance of homologous recombination deficient MGMT^low/MMR^proficient cancer cells to temozolomide Priority Research Paper

Lara H. El Touny, Curtis Hose, John Connelly, Erik Harris, Anne Monks, Angie B. Dull, Deborah F. Wilsker, Melinda G. Hollingshead, Michelle Gottholm-Ahalt, Sergio Y. Alcoser, Michael E. Mullendore, Ralph E. Parchment, James H. Doroshow, Beverly A. Teicher, Annamaria Rapisarda

Published Sep 28, 2021 · Vol. 12, No. 21 · pp. 2114-2130

Keywords: TMZ, MMR, ATR, HR, REV3L

Dishevelled-1 DIX and PDZ domain lysine residues regulate oncogenic Wnt signaling Research Paper

Monica Sharma, Isabel Castro-Piedras, Fahmida Rasha, Sabarish Ramachandran, Souad R. Sennoune, Kathryn Furr, Sharilyn Almodovar, Vadivel Ganapathy, Matthew B. Grisham, Rakhshanda Layeequr Rahman, Kevin Pruitt

Published Sep 28, 2021 · Vol. 12, No. 22 · pp. 2234-2251

Keywords: dishevelled (DVL), post-translational modification, lysine residue, gene expression, chromatin immunoprecipitation (ChIP)

Correction: PSC-derived Galectin-1 inducing epithelial-mesenchymal transition of pancreatic ductal adenocarcinoma cells by activating the NF-κB pathway Correction

Dong Tang, Jingqiu Zhang, Zhongxu Yuan, Hongpeng Zhang, Yang Chong, Yuqin Huang, Jie Wang, Qingquan Xiong, Sen Wang, Qi Wu, Ying Tian, Yongdie Lu, Xiao Ge, Wenjing Shen, Daorong Wang

Published Sep 25, 2021 · Vol. 12, No. 20 · pp. 2111-2113

P10s-PADRE vaccine combined with neoadjuvant chemotherapy in ER-positive breast cancer patients induces humoral and cellular immune responses Research Paper

Issam Makhoul, Saddam Mohammed Ibrahim, Muhammad Abu-Rmaileh, Fariba Jousheghany, Eric R. Siegel, Lora J. Rogers, John J. Lee, Sergio Pina-Oviedo, Ginell R. Post, J. Thaddeus Beck, Thomas Kieber-Emmons, Behjatolah Monzavi-Karbassi

Published Sep 16, 2021 · Vol. 12, No. 22 · pp. 2252-2265

Keywords: cancer vaccine, peptide mimotopes, combination therapy, breast cancer

TAK1-inhibitors are cytotoxic for multiple myeloma cells alone and in combination with melphalan Research Paper

Erling Håland, Ingrid Nyhus Moen, Elias Veidal, Hanne Hella, Kristine Misund, Tobias S. Slørdahl, Kristian K. Starheim

Published Sep 4, 2021 · Vol. 12, No. 21 · pp. 2158-2168

Keywords: multiple myeloma, TAK1, apoptosis, NF-κB, cancer treatment

Comparative microsomal proteomics of a model lung cancer cell line NCI-H23 reveals distinct differences between molecular profiles of 3D and 2D cultured cells Research Paper

Jan A. Kaczmarczyk, Rhonda R. Roberts, Brian T. Luke, King C. Chan, Carly M. Van Wagoner, Robin A. Felder, Richard G. Saul, Colantonio Simona, Josip Blonder

Published Sep 3, 2021 · Vol. 12, No. 20 · pp. 2022-2038

Keywords: lung cancer, proteomics, 2D vs. 3D cultured cells, preclinical testing model, drug target discovery

Multipeptide stimulated PBMCs generate T_EM/T_CM for adoptive cell therapy in multiple myeloma Research Paper

Trupti Vardam-Kaur, Latha B. Pathangey, Daniel J. McCormick, P. Leif Bergsagel, Peter A. Cohen, Sandra J. Gendler

Published Aug 27, 2021 · Vol. 12, No. 20 · pp. 2051-2067

Keywords: multiple myeloma, cellular therapy, CD4/CD8 T cells, peptides, immunotherapy

Impact factor and citation metrics in phase III cancer trials Research Paper

Joseph Abi Jaoude, Ramez Kouzy, Michael Rooney, Petria Thompson, Roshal Patel, Maddie C. Turner, Marc Ghabach, C. David Fuller, Bruce D. Minsky, Cullen M. Taniguchi, Ethan B. Ludmir

Published Aug 3, 2021 · Vol. 12, No. 18 · pp. 1780-1786

Keywords: oncology, journal impact factor, clinical trials, FDA, industry

Inhibition of the MAP2K7-JNK pathway with 5Z-7-oxozeaenol induces apoptosis in T-cell acute lymphoblastic leukemia Research Paper

Taylor J. Chen, Wa Du, Jacob J. Junco, Cory Seth Bridges, Ye Shen, Monica Puppi, Karen R. Rabin, H. Daniel Lacorazza

Published Jul 31, 2021 · Vol. 12, No. 18 · pp. 1787-1801

Keywords: T-ALL, MAP2K7, 5z-7-oxozeaenol

Interactions of multidomain pro-apoptotic and anti-apoptotic proteins in cancer cell death Review

Alexander Chota, Blassan P. George, Heidi Abrahamse

Published Jul 19, 2021 · Vol. 12, No. 16 · pp. 1615-1626

Keywords: apoptosis, caspases, cancer, Bcl-2 family proteins, p53

Correction: Oncogenic extracellular HSP70 disrupts the gap-junctional coupling between capillary cells Correction

Dominique Thuringer, Kevin Berthenet, Laurent Cronier, Gaetan Jego, Eric Solary, Carmen Garrido

Published Jul 13, 2021 · Vol. 12, No. 15 · pp. 1564-1565

JunD accentuates arecoline-induced disruption of tight junctions and promotes epithelial-to-mesenchymal transition by association with NEAT1 lncRNA Research Paper

Subarna Ghosh, Priyanka Dey Talukdar, Abhinandan Bhattacharjee, Sarbani Giri, Nitai Pada Bhattacharyya, Urmi Chatterji

Published Jul 2, 2021 · Vol. 12, No. 15 · pp. 1520-1539

Keywords: arecoline, tight junction, head and neck cancer, lncRNA-NEAT1, JunD

Hypofractionation: less is more? Research Perspective

Neethu Billy Graham Mariam, Yee Pei Song, Nuradh Joseph, Peter Hoskin, Kimberley Reeves, Nuria Porta, Nicholas James, Ananya Choudhury

Published Jun 29, 2021 · Vol. 12, No. 17 · pp. 1729-1733

Keywords: hypofractionation, BC2001, BCON, bladder cancer

Esomeprazole enhances the effect of ionizing radiation to improve tumor control Research Paper

Kassidy A. Hebert, Sergio Jaramillo, Wangjie Yu, Min Wang, Ratna Veeramachaneni, Vlad C. Sandulache, Andrew G. Sikora, Mark D. Bonnen, Ananth V. Annapragada, David Corry, Farrah Kheradmand, Raj K. Pandita, Michelle S. Ludwig, Tej K. Pandita, Shixia Huang, Cristian Coarfa, Sandra L. Grimm, Dimuthu Perera, George Miles, Yohannes T. Ghebre

Published Jun 19, 2021 · Vol. 12, No. 14 · pp. 1339-1353

Keywords: esomeprazole, proton pump inhibitors, ionizing radiation, radiosensitization, tumor control

Frame-shift mediated reduction of gain-of-function p53 R273H and deletion of the R273H C-terminus in breast cancer cells result in replication-stress sensitivity Priority Research Paper

Viola Ellison, George K. Annor, Clara Freedman, Gu Xiao, Devon Lundine, Elzbieta Freulich, Carol Prives, Jill Bargonetti

Published May 20, 2021 · Vol. 12, No. 12 · pp. 1128-1146

Keywords: mutant p53, gain-of-function, oligomerization, DNA replication, frame-shift

Role for Fgr and Numb in retinoic acid-induced differentiation and G0 arrest of non-APL AML cells Research Paper

Noor Kazim, Andrew Yen

Published May 11, 2021 · Vol. 12, No. 12 · pp. 1147-1164

Keywords: retinoic acid(RA), FGR, Numb, non-APL AML, cell differentiation

A novel E2F1-regulated lncRNA, LAPAS1, is required for S phase progression and cell proliferation Research Paper

Esther Baruch, Tali Nizri-Megnaji, Oron Berkowitz, Doron Ginsberg

Published May 7, 2021 · Vol. 12, No. 11 · pp. 1072-1082

Keywords: lncRNA, E2F, cell cycle, cell proliferation

Genome wide DNA methylation landscape reveals glioblastoma’s influence on epigenetic changes in tumor infiltrating CD4+ T cells Research Paper

Marpe Bam, Sreenivasulu Chintala, Kaleigh Fetcko, Brooke Carmen Williamsen, Seema Siraj, Sheng Liu, Jun Wan, Xiaoling Xuei, Yunlong Liu, Adam T. Leibold, Mahua Dey

Published Apr 25, 2021 · Vol. 12, No. 10 · pp. 967-981

Keywords: glioblastoma, malignant glioma, CD4+ T cell, DNA methylation, brain cancer

Creation of a new class of radiosensitizers for glioblastoma based on the mibefradil pharmacophore Research Paper

Sateja Paradkar, James Herrington, Adam Hendricson, Piyasena Hewawasam, Mark Plummer, Denton Hoyer, Ranjini K. Sundaram, Yulia V. Surovtseva, Ranjit S. Bindra

Published Mar 27, 2021 · Vol. 12, No. 9 · pp. 891-906

Keywords: glioblastoma, radiosensitizers, mibefradil, DNA repair, alternative non-homologous end joining

Decreased expression of the translation factor eIF3e induces senescence in breast cancer cells via suppression of PARP1 and activation of mTORC1 Research Paper

Christelle Morris, Sébastien Durand, Pierre Jalinot

Published Mar 13, 2021 · Vol. 12, No. 7 · pp. 649-664

Keywords: breast cancer, senescence-associated secretory phenotype, eIF3, PARP1, mTORC1

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ATR inhibition reverses the resistance of homologous recombination deficient MGMT^low/MMR^proficient cancer cells to temozolomide Priority Research Paper

Dishevelled-1 DIX and PDZ domain lysine residues regulate oncogenic Wnt signaling Research Paper

Correction: PSC-derived Galectin-1 inducing epithelial-mesenchymal transition of pancreatic ductal adenocarcinoma cells by activating the NF-κB pathway Correction

P10s-PADRE vaccine combined with neoadjuvant chemotherapy in ER-positive breast cancer patients induces humoral and cellular immune responses Research Paper

TAK1-inhibitors are cytotoxic for multiple myeloma cells alone and in combination with melphalan Research Paper

Comparative microsomal proteomics of a model lung cancer cell line NCI-H23 reveals distinct differences between molecular profiles of 3D and 2D cultured cells Research Paper

Multipeptide stimulated PBMCs generate T_EM/T_CM for adoptive cell therapy in multiple myeloma Research Paper

Impact factor and citation metrics in phase III cancer trials Research Paper

Inhibition of the MAP2K7-JNK pathway with 5Z-7-oxozeaenol induces apoptosis in T-cell acute lymphoblastic leukemia Research Paper

Interactions of multidomain pro-apoptotic and anti-apoptotic proteins in cancer cell death Review

Correction: Oncogenic extracellular HSP70 disrupts the gap-junctional coupling between capillary cells Correction

JunD accentuates arecoline-induced disruption of tight junctions and promotes epithelial-to-mesenchymal transition by association with NEAT1 lncRNA Research Paper

Hypofractionation: less is more? Research Perspective

Esomeprazole enhances the effect of ionizing radiation to improve tumor control Research Paper

Frame-shift mediated reduction of gain-of-function p53 R273H and deletion of the R273H C-terminus in breast cancer cells result in replication-stress sensitivity Priority Research Paper

Role for Fgr and Numb in retinoic acid-induced differentiation and G0 arrest of non-APL AML cells Research Paper

A novel E2F1-regulated lncRNA, LAPAS1, is required for S phase progression and cell proliferation Research Paper

Genome wide DNA methylation landscape reveals glioblastoma’s influence on epigenetic changes in tumor infiltrating CD4+ T cells Research Paper

Creation of a new class of radiosensitizers for glioblastoma based on the mibefradil pharmacophore Research Paper

Decreased expression of the translation factor eIF3e induces senescence in breast cancer cells via suppression of PARP1 and activation of mTORC1 Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

ATR inhibition reverses the resistance of homologous recombination deficient MGMTlow/MMRproficient cancer cells to temozolomide Priority Research Paper

Dishevelled-1 DIX and PDZ domain lysine residues regulate oncogenic Wnt signaling Research Paper

Correction: PSC-derived Galectin-1 inducing epithelial-mesenchymal transition of pancreatic ductal adenocarcinoma cells by activating the NF-κB pathway Correction

P10s-PADRE vaccine combined with neoadjuvant chemotherapy in ER-positive breast cancer patients induces humoral and cellular immune responses Research Paper

TAK1-inhibitors are cytotoxic for multiple myeloma cells alone and in combination with melphalan Research Paper

Comparative microsomal proteomics of a model lung cancer cell line NCI-H23 reveals distinct differences between molecular profiles of 3D and 2D cultured cells Research Paper

Multipeptide stimulated PBMCs generate TEM/TCM for adoptive cell therapy in multiple myeloma Research Paper

Impact factor and citation metrics in phase III cancer trials Research Paper

Inhibition of the MAP2K7-JNK pathway with 5Z-7-oxozeaenol induces apoptosis in T-cell acute lymphoblastic leukemia Research Paper

Interactions of multidomain pro-apoptotic and anti-apoptotic proteins in cancer cell death Review

Correction: Oncogenic extracellular HSP70 disrupts the gap-junctional coupling between capillary cells Correction

JunD accentuates arecoline-induced disruption of tight junctions and promotes epithelial-to-mesenchymal transition by association with NEAT1 lncRNA Research Paper

Hypofractionation: less is more? Research Perspective

Esomeprazole enhances the effect of ionizing radiation to improve tumor control Research Paper

Frame-shift mediated reduction of gain-of-function p53 R273H and deletion of the R273H C-terminus in breast cancer cells result in replication-stress sensitivity Priority Research Paper

Role for Fgr and Numb in retinoic acid-induced differentiation and G0 arrest of non-APL AML cells Research Paper

A novel E2F1-regulated lncRNA, LAPAS1, is required for S phase progression and cell proliferation Research Paper

Genome wide DNA methylation landscape reveals glioblastoma’s influence on epigenetic changes in tumor infiltrating CD4+ T cells Research Paper

Creation of a new class of radiosensitizers for glioblastoma based on the mibefradil pharmacophore Research Paper

Decreased expression of the translation factor eIF3e induces senescence in breast cancer cells via suppression of PARP1 and activation of mTORC1 Research Paper

ATR inhibition reverses the resistance of homologous recombination deficient MGMT^low/MMR^proficient cancer cells to temozolomide Priority Research Paper

Multipeptide stimulated PBMCs generate T_EM/T_CM for adoptive cell therapy in multiple myeloma Research Paper