The Oncosearch | Oncotarget

Ex vivo analysis of DNA repair targeting in extreme rare cutaneous apocrine sweat gland carcinoma Research Paper

Rami Mäkelä, Ville Härmä, Nibal Badra Fajardo, Greg Wells, Zoi Lygerou, Olle Sangfelt, Juha Kononen, Juha K. Rantala

Published May 6, 2021 · Vol. 12, No. 11 · pp. 1100-1109

Keywords: cutaneous apocrine sweat gland carcinoma, ex vivo drug screening, DNA repair, PALB2, rare cancer

FGFR1, a novel biomarker for metastatic castration-resistant prostate cancer? News

Leandro H. Gallo

Published Apr 27, 2021 · Vol. 12, No. 11 · pp. 1026-1028

Keywords: prostate cancer, metastasis, cancer stem cells, castration-resistant, tyrosine kinase inhibitors

Transcriptome analyses of urine RNA reveal tumor markers for human bladder cancer: validated amplicons for RT-qPCR-based detection Research Paper

Josephine Dubois, Jacqueline Rueger, Bernhard Haubold, Rosel Kretschmer-Kazemi Far, Georg Sczakiel

Published Apr 24, 2021 · Vol. 12, No. 10 · pp. 1011-1023

Keywords: tumor diagnostics, non-invasive, urine RNA, biomarker, transcriptome analysis

Inhibitory effects of Tomivosertib in acute myeloid leukemia Research Paper

Milagros Suarez, Gavin T. Blyth, Alain A. Mina, Ewa M. Kosciuczuk, Blazej Dolniak, Shira Dinner, Jessica K. Altman, Elizabeth A. Eklund, Diana Saleiro, Elspeth M. Beauchamp, Leonidas C. Platanias

Published Apr 24, 2021 · Vol. 12, No. 10 · pp. 955-966

Keywords: MNK, Tomivosertib, acute myeloid leukemia, eIF4E

The acylfulvene alkylating agent, LP-184, retains nanomolar potency in non-small cell lung cancer carrying otherwise therapy-refractory mutations Research Paper

Aditya Kulkarni, Joseph Ryan McDermott, Umesh Kathad, Rama Modali, Jean-Philippe Richard, Panna Sharma, Kishor Bhatia

Published Apr 5, 2021 · Vol. 12, No. 8 · pp. 791-806

Keywords: non-small cell lung cancer, acylfulvene, alkylating agent, PTGR1, LP-184

Urine protein biomarkers of bladder cancer arising from 16-plex antibody-based screens Research Paper

Kamala Vanarsa, Shereen Enan, Pooja Patel, Briony Strachan, Anto Sam Crosslee Louis Sam Titus, Aphrihl Dennis, Yair Lotan, Chandra Mohan

Published Mar 31, 2021 · Vol. 12, No. 8 · pp. 783-790

Keywords: urothelial, proteomics, targeted screens, interleukins, inflammation

Controlling for cellular heterogeneity using single-cell deconvolution of gene expression reveals novel markers of colorectal tumors exhibiting microsatellite instability Research Paper

Matthew A.M. Devall, Graham Casey

Published Mar 30, 2021 · Vol. 12, No. 8 · pp. 767-782

Keywords: colorectal cancer, single-cell deconvolution, microsatellite instability, RNA-sequencing, enteroendocrine

Creation of a new class of radiosensitizers for glioblastoma based on the mibefradil pharmacophore Research Paper

Sateja Paradkar, James Herrington, Adam Hendricson, Piyasena Hewawasam, Mark Plummer, Denton Hoyer, Ranjini K. Sundaram, Yulia V. Surovtseva, Ranjit S. Bindra

Published Mar 27, 2021 · Vol. 12, No. 9 · pp. 891-906

Keywords: glioblastoma, radiosensitizers, mibefradil, DNA repair, alternative non-homologous end joining

Loss of CPAP causes sustained EGFR signaling and epithelial-mesenchymal transition in oral cancer Research Paper

Radhika R. Gudi, Harinarayanan Janakiraman, Philip H. Howe, Viswanathan Palanisamy, Chenthamarakshan Vasu

Published Mar 27, 2021 · Vol. 12, No. 8 · pp. 807-822

Keywords: tumorigenesis, epithelial-mesenchymal transition, oral squamous cell carcinoma, EGFR, CPAP

Prognostic and therapeutic value of the Hippo pathway, RABL6A, and p53-MDM2 axes in sarcomas Research Paper

Chandni Desai, Jon Thomason, Jordan L. Kohlmeyer, Anna C. Reisetter, Parmanand Ahirwar, Khadijeh Jahanseir, Mariah Leidinger, Georgina Ofori-Amanfo, Karen Fritchie, Sadanandan E. Velu, Patrick Breheny, Dawn E. Quelle, Munir R. Tanas

Published Mar 21, 2021 · Vol. 12, No. 8 · pp. 740-755

Keywords: sarcoma, YAP, TAZ, p53-MDM2, RABL6A

Decreased expression of the translation factor eIF3e induces senescence in breast cancer cells via suppression of PARP1 and activation of mTORC1 Research Paper

Christelle Morris, Sébastien Durand, Pierre Jalinot

Published Mar 13, 2021 · Vol. 12, No. 7 · pp. 649-664

Keywords: breast cancer, senescence-associated secretory phenotype, eIF3, PARP1, mTORC1

Landscape of somatic mutations in breast cancer: new opportunities for targeted therapies in Saudi Arabian patients Research Paper

Duna H. Barakeh, Rasha Aljelaify, Yara Bashawri, Amal Almutairi, Fatimah Alqubaishi, Mohammed Alnamnakani, Latifa Almubarak, Abdulrahman Al Naeem, Fatema Almushawah, May Alrashed, Malak Abedalthagafi

Published Feb 27, 2021 · Vol. 12, No. 7 · pp. 686-697

Keywords: breast cancer, PIK3CA, BCa, Saudi Arabia, BRCA

A high-content AlphaScreen™ identifies E6-specific small molecule inhibitors as potential therapeutics for HPV⁺ head and neck squamous cell carcinomas Research Paper

Lennox Chitsike, Chung-Hsiang Yuan, Anuradha Roy, Kristopher Boyle, Penelope J. Duerksen-Hughes

Published Feb 22, 2021 · Vol. 12, No. 6 · pp. 549-561

Keywords: HNSCC, HPV, E6, AlphaScreen™, 30-hydroxygambogic acid

Development of a ghrelin receptor inverse agonist for positron emission tomography Research Paper

Ralf Bergmann, Constance Chollet, Sylvia Els-Heindl, Martin Ullrich, Nicole Berndt, Jens Pietzsch, Domokos Máthé, Michael Bachmann, Annette G. Beck-Sickinger

Published Feb 7, 2021 · Vol. 12, No. 5 · pp. 450-474

Keywords: cancer, prostate cancer, growth hormone secretagogue receptor (GHS-R), small animal imaging, copper-64

Multi-modal effects of 1B3, a novel synthetic miR-193a-3p mimic, support strong potential for therapeutic intervention in oncology Research Paper

Bryony J. Telford, Sanaz Yahyanejad, Thijs de Gunst, Harm C. den Boer, Rogier M. Vos, Marieke Stegink, Marion T.J. van den Bosch, Mir Farshid Alemdehy, Laurens A.H. van Pinxteren, Roel Q.J. Schaapveld, Michel Janicot

Published Feb 7, 2021 · Vol. 12, No. 5 · pp. 422-439

Keywords: miR-193a-3p, microRNA mimic, microRNA delivery in vivo, pleiotropic mechanism of microRNA,

Fine–mapping of two differentiated thyroid carcinoma susceptibility loci at 2q35 and 8p12 in Europeans, Melanesians and Polynesians Research Paper

Julie Guibon, Pierre-Emmanuel Sugier, Om Kulkarni, Mojgan Karimi, Delphine Bacq-Daian, Céline Besse, Anne Boland, Elisabeth Adjadj, Frédérique Rachédi, Carole Rubino, Constance Xhaard, Claire Mulot, Pierre Laurent-Puig, Anne-Valérie Guizard, Claire Schvartz, Rosa Maria Ortiz, Yan Ren, Evgenia Ostroumova, Jean-François Deleuze, Marie-Christine Boutron-Ruault, Ausrele Kesminiene, Florent De Vathaire, Pascal Guénel, Fabienne Lesueur, Thérèse Truong

Published Feb 3, 2021 · Vol. 12, No. 5 · pp. 493-506

Keywords: thyroid cancer, cancer genetics, case-control study, fine-mapping study, single nucleotide polymorphism

A novel isoform of Homeodomain-interacting protein kinase-2 promotes YAP/TEAD transcriptional activity in NSCLC cells Research Paper

Yuyuan Dai, Hiroyuki Kyoyama, Yi-Lin Yang, Yucheng Wang, Shu Liu, Yinghao Wang, Jian-Hua Mao, Zhidong Xu, Kazutsugu Uematsu, David M. Jablons, Liang You

Published Jan 15, 2021 · Vol. 12, No. 3 · pp. 173-184

Keywords: Homeodomain Interacting Protein Kinase 2 (HIPK2), non-small cell lung cancer (NSCLC), yes-associated protein (YAP), HIPK2 isoform, 4,5,6,7-tetrabromo-2-(1H-imidazol-2-yl)isoindoline-1,3-dione (TBID)

Downregulation of SOX2 by inhibition of Usp9X induces apoptosis in melanoma Research Paper

Harish Potu, Malathi Kandarpa, Luke F. Peterson, Alison Durham, Nicholas J. Donato, Moshe Talpaz

Published Jan 12, 2021 · Vol. 12, No. 3 · pp. 160-172

Keywords: melanoma, deubiquitinase (DUB) enzyme, transcription factors, USP9X, DUB inhibitor

A priori prediction of response in multicentre locally advanced breast cancer (LABC) patients using quantitative ultrasound and derivative texture methods Research Paper

Laurentius O. Osapoetra, Lakshmanan Sannachi, Karina Quiaoit, Archya Dasgupta, Daniel DiCenzo, Kashuf Fatima, Frances Wright, Robert Dinniwell, Maureen Trudeau, Sonal Gandhi, William Tran, Michael C. Kolios, Wei Yang, Gregory J. Czarnota

Published Jan 6, 2021 · Vol. 12, No. 2 · pp. 81-94

Keywords: radiomics, breast cancer, texture-derivate, quantitative ultrasound, neoadjuvant chemotherapy

Characterization of FGFR signaling in prostate cancer stem cells and inhibition via TKI treatment Research Paper

Juyeon Ko, April N. Meyer, Martin Haas, Daniel J. Donoghue

Published Dec 23, 2020 · Vol. 12, No. 1 · pp. 22-36

Keywords: metastatic castrate-resistant prostate cancer, spheroid culture, tyrosine kinase inhibitor

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Ex vivo analysis of DNA repair targeting in extreme rare cutaneous apocrine sweat gland carcinoma Research Paper

FGFR1, a novel biomarker for metastatic castration-resistant prostate cancer? News

Transcriptome analyses of urine RNA reveal tumor markers for human bladder cancer: validated amplicons for RT-qPCR-based detection Research Paper

Inhibitory effects of Tomivosertib in acute myeloid leukemia Research Paper

The acylfulvene alkylating agent, LP-184, retains nanomolar potency in non-small cell lung cancer carrying otherwise therapy-refractory mutations Research Paper

Urine protein biomarkers of bladder cancer arising from 16-plex antibody-based screens Research Paper

Controlling for cellular heterogeneity using single-cell deconvolution of gene expression reveals novel markers of colorectal tumors exhibiting microsatellite instability Research Paper

Creation of a new class of radiosensitizers for glioblastoma based on the mibefradil pharmacophore Research Paper

Loss of CPAP causes sustained EGFR signaling and epithelial-mesenchymal transition in oral cancer Research Paper

Prognostic and therapeutic value of the Hippo pathway, RABL6A, and p53-MDM2 axes in sarcomas Research Paper

Decreased expression of the translation factor eIF3e induces senescence in breast cancer cells via suppression of PARP1 and activation of mTORC1 Research Paper

Landscape of somatic mutations in breast cancer: new opportunities for targeted therapies in Saudi Arabian patients Research Paper

A high-content AlphaScreen™ identifies E6-specific small molecule inhibitors as potential therapeutics for HPV⁺ head and neck squamous cell carcinomas Research Paper

Development of a ghrelin receptor inverse agonist for positron emission tomography Research Paper

Multi-modal effects of 1B3, a novel synthetic miR-193a-3p mimic, support strong potential for therapeutic intervention in oncology Research Paper

Fine–mapping of two differentiated thyroid carcinoma susceptibility loci at 2q35 and 8p12 in Europeans, Melanesians and Polynesians Research Paper

A novel isoform of Homeodomain-interacting protein kinase-2 promotes YAP/TEAD transcriptional activity in NSCLC cells Research Paper

Downregulation of SOX2 by inhibition of Usp9X induces apoptosis in melanoma Research Paper

A priori prediction of response in multicentre locally advanced breast cancer (LABC) patients using quantitative ultrasound and derivative texture methods Research Paper

Characterization of FGFR signaling in prostate cancer stem cells and inhibition via TKI treatment Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Ex vivo analysis of DNA repair targeting in extreme rare cutaneous apocrine sweat gland carcinoma Research Paper

FGFR1, a novel biomarker for metastatic castration-resistant prostate cancer? News

Transcriptome analyses of urine RNA reveal tumor markers for human bladder cancer: validated amplicons for RT-qPCR-based detection Research Paper

Inhibitory effects of Tomivosertib in acute myeloid leukemia Research Paper

The acylfulvene alkylating agent, LP-184, retains nanomolar potency in non-small cell lung cancer carrying otherwise therapy-refractory mutations Research Paper

Urine protein biomarkers of bladder cancer arising from 16-plex antibody-based screens Research Paper

Controlling for cellular heterogeneity using single-cell deconvolution of gene expression reveals novel markers of colorectal tumors exhibiting microsatellite instability Research Paper

Creation of a new class of radiosensitizers for glioblastoma based on the mibefradil pharmacophore Research Paper

Loss of CPAP causes sustained EGFR signaling and epithelial-mesenchymal transition in oral cancer Research Paper

Prognostic and therapeutic value of the Hippo pathway, RABL6A, and p53-MDM2 axes in sarcomas Research Paper

Decreased expression of the translation factor eIF3e induces senescence in breast cancer cells via suppression of PARP1 and activation of mTORC1 Research Paper

Landscape of somatic mutations in breast cancer: new opportunities for targeted therapies in Saudi Arabian patients Research Paper

A high-content AlphaScreen™ identifies E6-specific small molecule inhibitors as potential therapeutics for HPV+ head and neck squamous cell carcinomas Research Paper

Development of a ghrelin receptor inverse agonist for positron emission tomography Research Paper

Multi-modal effects of 1B3, a novel synthetic miR-193a-3p mimic, support strong potential for therapeutic intervention in oncology Research Paper

Fine–mapping of two differentiated thyroid carcinoma susceptibility loci at 2q35 and 8p12 in Europeans, Melanesians and Polynesians Research Paper

A novel isoform of Homeodomain-interacting protein kinase-2 promotes YAP/TEAD transcriptional activity in NSCLC cells Research Paper

Downregulation of SOX2 by inhibition of Usp9X induces apoptosis in melanoma Research Paper

A priori prediction of response in multicentre locally advanced breast cancer (LABC) patients using quantitative ultrasound and derivative texture methods Research Paper

Characterization of FGFR signaling in prostate cancer stem cells and inhibition via TKI treatment Research Paper

A high-content AlphaScreen™ identifies E6-specific small molecule inhibitors as potential therapeutics for HPV⁺ head and neck squamous cell carcinomas Research Paper