The Oncosearch | Oncotarget

Integrated stress response (ISR) activation and apoptosis through HRI kinase by PG3 and other p53 pathway-restoring cancer therapeutics Research Paper

Xiaobing Tian, Wafik S. El-Deiry

Published Jul 26, 2024 · Vol. 15, No. 1 · pp. 614-633

Keywords: mutant p53, integrated stress response (ISR), ATF4, HRI, ClpP

Prognostic and therapeutic insights into MIF, DDT, and CD74 in melanoma Research Paper

Caroline Naomi Valdez, Gabriela Athziri Sánchez-Zuno, Lais Osmani, Wael Ibrahim, Anjela Galan, Antonietta Bacchiocchi, Ruth Halaban, Rajan P. Kulkarni, Insoo Kang, Richard Bucala, Thuy Tran

Published Jul 15, 2024 · Vol. 15, No. 1 · pp. 507-520

Keywords: MIF, DDT, melanoma, immune checkpoint inhibition, cancer transcriptomics

Improved efficacy of pembrolizumab combined with soluble EphB4-albumin in HPV-negative EphrinB2 positive head neck squamous cell carcinoma Research Paper

Alexandra Jackovich, Barbara J. Gitlitz, Justin Wayne Wong Tiu-lim, Vinay Duddalwar, Kevin George King, Anthony B. El-Khoueiry, Jacob Stephen Thomas, Denice Tsao-Wei, David I. Quinn, Parkash S. Gill, Jorge J. Nieva

Published Jun 29, 2024 · Vol. 15, No. 1 · pp. 444-458

Keywords: EphrinB2, EphB4, HNSCC, pembrolizumab, HPV-negative

Synergistic cytotoxicity of histone deacetylase and poly-ADP ribose polymerase inhibitors and decitabine in pancreatic cancer cells: Implications for novel therapy Research Paper

Benigno C. Valdez, Apostolia M. Tsimberidou, Bin Yuan, Yago Nieto, Mehmet A. Baysal, Abhijit Chakraborty, Clark R. Andersen, Borje S. Andersson

Published May 25, 2024 · Vol. 15, No. 1 · pp. 361-373

Keywords: decitabine, HDAC inhibitors, pancreatic cancer, PARP inhibitors, synergistic cytotoxicity

Novel therapeutic bispecific antibodies for B-cell lymphoma targeting IgM and other antigens on the B-cell surface Research Paper

Takahiro Ohashi, Sayuri Terada, Shinsuke Hiramoto, Yuko Nagata, Hirokazu Suzuki, Hitoshi Miyashita, Tetsuo Sasaki, Yasukatsu Tsukada, Keiko Fukushima

Published Mar 29, 2024 · Vol. 15, No. 1 · pp. 256-274

Keywords: bispecific antibody, Cys1m, IgM, lymphoma, cynomolgus monkey

BCAS1 defines a heterogeneous cell population in diffuse gliomas Research Paper

Raquel Morales-Gallel, María José Ulloa-Navas, Patricia García-Tárraga, Ricardo Prat-Acín, Gaspar Reynés, Pedro Pérez-Borredá, Luis Rubio, Vivian Capilla-González, Jaime Ferrer-Lozano, José Manuel García-Verdugo

Published Jan 10, 2024 · Vol. 15, No. 1 · pp. 49-64

Keywords: brain tumor, diffuse glioma, oligodendroglioma, glioblastoma, BCAS1

Combining causal and correlative approaches to discover biomarkers of response to paclitaxel Research Perspective

Alberto Moscona-Nissan, Karl J. Habashy, Victor A. Arrieta, Adam M. Sonabend, Crismita Dmello

Published Jan 2, 2024 · Vol. 15, No. 1 · pp. 117-122

Keywords: glioblastoma, predictive biomarker, CRISPR screen, paclitaxel

Preclinical and clinical evaluation of the Janus Kinase inhibitor ruxolitinib in multiple myeloma Research Perspective

Ashley Del Dosso, Elizabeth Tadevosyan, James R. Berenson

Published Dec 23, 2023 · Vol. 15, No. 1 · pp. 65-75

Keywords: multiple myeloma, ruxolitinib, JAK/STAT, cytokine, clinical trial

Transformation-associated recombination (TAR) cloning and its applications for gene function; genome architecture and evolution; biotechnology and biomedicine Review

Natalay Kouprina, Vladimir Larionov

Published Dec 19, 2023 · Vol. 14, No. 1 · pp. 1009-1033

Keywords: transformation-associated recombination, TAR, microbes, biomedicine, biotechnology

Current perspectives on the management of refractory or relapsed classic hodgkin lymphoma in Brazil: Balancing efficacy, safety, and tolerability Review

Flávia Dias Xavier, Danielle Leão Cordeiro de Farias, Abrahão Elias Hallack Neto, Glaciano Nogueira Ribeiro, Marco Aurelio Salvino de Araujo, Thiago Xavier Carneiro, Otavio Cesar Carvalho Guimarães Baiocchi

Published Dec 5, 2023 · Vol. 14, No. 1 · pp. 977-994

Keywords: brentuximab vedotin, drug therapy, hodgkin lymphoma, nivolumab, pembrolizumab

Determination of genetic predisposition to early breast cancer in women of Kazakh ethnicity Research Paper

Gulnur Zhunussova, Nazgul Omarbayeva, Dilyara Kaidarova, Saltanat Abdikerim, Natalya Mit, Ilya Kisselev, Kanagat Yergali, Aigul Zhunussova, Tatyana Goncharova, Aliya Abdrakhmanova, Leyla Djansugurova

Published Sep 25, 2023 · Vol. 14, No. 1 · pp. 860-877

Keywords: early-onset breast cancer, triple negative breast cancer, next-generation sequencing, pathogenic variant, Kazakh population

Transcriptomic analysis identifies four novel receptors potentially linking endometrial cancer with polycystic ovary syndrome and generates a transcriptomic atlas Research Paper

Fatma Alqutami, Mahmood Hachim, Charlie Hodgman, William Atiomo

Published Sep 17, 2023 · Vol. 14, No. 1 · pp. 825-835

Keywords: polycystic ovary syndrome, endometrial cancer, transcriptomics, IGF1, in-silico

Addendum: Novel inflammation-combined prognostic index to predict survival outcomes in patients with gastric cancer Addendum

Noriyuki Hirahara, Takeshi Matsubara, Shunsuke Kaji, Hikota Hayashi, Yohei Sasaki, Koki Kawakami, Ryoji Hyakudomi, Tetsu Yamamoto, Yoshitsugu Tajima

Published Sep 7, 2023

Development of a multiplex assay to assess activated p300/CBP in circulating prostate tumor cells Research Paper

Mikolaj Filon, Bing Yang, Tanaya A. Purohit, Jennifer Schehr, Anupama Singh, Marcelo Bigarella, Peter Lewis, John Denu, Joshua Lang, David F. Jarrard

Published Jul 11, 2023 · Vol. 14, No. 1 · pp. 738-746

Keywords: prostate cancer, circulating tumor cells, p300/CBP

The uncharacterized transcript KIAA0930 confers a cachexic phenotype on cancer cells Research Paper

Takahiro Yamakawa, Guoxiang Zhang, Liza Bengrine Najjar, Chun Li, Keiichi Itakura

Published Jul 8, 2023 · Vol. 14, No. 1 · pp. 723-737

Keywords: KIAA0930, cancer cachexia, muscle atrophy, inflammatory cytokines/chemokines, protein secretion

Targeting Ras with protein engineering Review

Atilio Tomazini, Julia M. Shifman

Published Jun 21, 2023 · Vol. 14, No. 1 · pp. 672-687

Keywords: Ras oncogene, anti-Ras therapeutics, Ras targeting, protein engineering, protein design

Deciphering the mechanisms of action of progesterone in breast cancer Research Perspective

Gaurav Chakravorty, Suhail Ahmad, Mukul S. Godbole, Sudeep Gupta, Rajendra A. Badwe, Amit Dutt

Published Jun 5, 2023 · Vol. 14, No. 1 · pp. 660-667

Keywords: breast cancer, progesterone, DSCAM-AS1, endocrine therapy

Addendum: ROS1-GOPC/FIG: a novel gene fusion in hepatic angiosarcoma Addendum

Eric I. Marks, Sahithi Pamarthy, Don Dizon, Ari Birnbaum, Evgeny Yakirevich, Howard Safran, Benedito A. Carneiro

Published May 20, 2023 · Vol. 14, No. 1 · pp. 515-515

Combined targeting of HEDGEHOG signaling and BRD4 as a novel therapeutic option against melanoma Editorial

Silvia Pietrobono, Barbara Stecca

Published May 13, 2023 · Vol. 14, No. 1 · pp. 526-527

Keywords: melanoma, hedgehog signaling, BRD4, SOX2, GLI1

Correction: A novel mechanism of regulation of the oncogenic transcription factor GLI3 by toll-like receptor signaling Correction

Stephan J. Matissek, Mona Karbalivand, Weiguo Han, Ava Boutilier, Estefania Yzar-Garcia, Laura L. Kehoe, Devin Storm Gardner, Adam Hage, Krista Fleck, Vicki Jeffers, Ricardo Rajsbaum, Sherine F. Elsawa

Published May 10, 2023 · Vol. 14, No. 1 · pp. 448-448

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Integrated stress response (ISR) activation and apoptosis through HRI kinase by PG3 and other p53 pathway-restoring cancer therapeutics Research Paper

Prognostic and therapeutic insights into MIF, DDT, and CD74 in melanoma Research Paper

Improved efficacy of pembrolizumab combined with soluble EphB4-albumin in HPV-negative EphrinB2 positive head neck squamous cell carcinoma Research Paper

Synergistic cytotoxicity of histone deacetylase and poly-ADP ribose polymerase inhibitors and decitabine in pancreatic cancer cells: Implications for novel therapy Research Paper

Novel therapeutic bispecific antibodies for B-cell lymphoma targeting IgM and other antigens on the B-cell surface Research Paper

BCAS1 defines a heterogeneous cell population in diffuse gliomas Research Paper

Combining causal and correlative approaches to discover biomarkers of response to paclitaxel Research Perspective

Preclinical and clinical evaluation of the Janus Kinase inhibitor ruxolitinib in multiple myeloma Research Perspective

Transformation-associated recombination (TAR) cloning and its applications for gene function; genome architecture and evolution; biotechnology and biomedicine Review

Current perspectives on the management of refractory or relapsed classic hodgkin lymphoma in Brazil: Balancing efficacy, safety, and tolerability Review

Determination of genetic predisposition to early breast cancer in women of Kazakh ethnicity Research Paper

Transcriptomic analysis identifies four novel receptors potentially linking endometrial cancer with polycystic ovary syndrome and generates a transcriptomic atlas Research Paper

Addendum: Novel inflammation-combined prognostic index to predict survival outcomes in patients with gastric cancer Addendum

Development of a multiplex assay to assess activated p300/CBP in circulating prostate tumor cells Research Paper

The uncharacterized transcript KIAA0930 confers a cachexic phenotype on cancer cells Research Paper

Targeting Ras with protein engineering Review

Deciphering the mechanisms of action of progesterone in breast cancer Research Perspective

Addendum: ROS1-GOPC/FIG: a novel gene fusion in hepatic angiosarcoma Addendum

Combined targeting of HEDGEHOG signaling and BRD4 as a novel therapeutic option against melanoma Editorial

Correction: A novel mechanism of regulation of the oncogenic transcription factor GLI3 by toll-like receptor signaling Correction

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Integrated stress response (ISR) activation and apoptosis through HRI kinase by PG3 and other p53 pathway-restoring cancer therapeutics Research Paper

Prognostic and therapeutic insights into MIF, DDT, and CD74 in melanoma Research Paper

Improved efficacy of pembrolizumab combined with soluble EphB4-albumin in HPV-negative EphrinB2 positive head neck squamous cell carcinoma Research Paper

Synergistic cytotoxicity of histone deacetylase and poly-ADP ribose polymerase inhibitors and decitabine in pancreatic cancer cells: Implications for novel therapy Research Paper

Novel therapeutic bispecific antibodies for B-cell lymphoma targeting IgM and other antigens on the B-cell surface Research Paper

BCAS1 defines a heterogeneous cell population in diffuse gliomas Research Paper

Combining causal and correlative approaches to discover biomarkers of response to paclitaxel Research Perspective

Preclinical and clinical evaluation of the Janus Kinase inhibitor ruxolitinib in multiple myeloma Research Perspective

Transformation-associated recombination (TAR) cloning and its applications for gene function; genome architecture and evolution; biotechnology and biomedicine Review

Current perspectives on the management of refractory or relapsed classic hodgkin lymphoma in Brazil: Balancing efficacy, safety, and tolerability Review

Determination of genetic predisposition to early breast cancer in women of Kazakh ethnicity Research Paper

Transcriptomic analysis identifies four novel receptors potentially linking endometrial cancer with polycystic ovary syndrome and generates a transcriptomic atlas Research Paper

Addendum: Novel inflammation-combined prognostic index to predict survival outcomes in patients with gastric cancer Addendum

Development of a multiplex assay to assess activated p300/CBP in circulating prostate tumor cells Research Paper

The uncharacterized transcript KIAA0930 confers a cachexic phenotype on cancer cells Research Paper

Targeting Ras with protein engineering Review

Deciphering the mechanisms of action of progesterone in breast cancer Research Perspective

Addendum: ROS1-GOPC/FIG: a novel gene fusion in hepatic angiosarcoma Addendum

Combined targeting of HEDGEHOG signaling and BRD4 as a novel therapeutic option against melanoma Editorial

Correction: A novel mechanism of regulation of the oncogenic transcription factor GLI3 by toll-like receptor signaling Correction