The Oncosearch | Oncotarget

Pan-drug and drug-specific mechanisms of 5-FU, irinotecan (CPT-11), oxaliplatin, and cisplatin identified by comparison of transcriptomic and cytokine responses of colorectal cancer cells Research Paper

Lindsey Carlsen, Christoph Schorl, Kelsey Huntington, Liz Hernandez-Borrero, Aakash Jhaveri, Shengliang Zhang, Lanlan Zhou, Wafik S. El-Deiry

Published Sep 8, 2021 · Vol. 12, No. 20 · pp. 2006-2021

Keywords: chemotherapy mechanism, colon cancer, 5-fluorouracil, irinotecan, oxaliplatin

Polyclonal on- and off-target resistance mutations in an EML4-ALK positive non-small cell lung cancer patient under ALK inhibition Case Report

Marcel Kemper, Georg Evers, Arik Bernard Schulze, Jan Sperveslage, Christoph Schülke, Georg Lenz, Thomas Herold, Wolfgang Hartmann, Hans-Ulrich Schildhaus, Annalen Bleckmann

Published Aug 23, 2021 · Vol. 12, No. 19 · pp. 1946-1952

Keywords: NSCLC, resistance mutations, ALK, KRAS, ALK inhibitors

Correction: Antitumor activity of S116836, a novel tyrosine kinase inhibitor, against imatinib-resistant FIP1L1-PDGFRα-expressing cells Correction

Yingying Shen, Xiaomei Ren, Ke Ding, Zhang Zhang, Deping Wang, Jingxuan Pan

Published Aug 21, 2021

Novel insights into the molecular mechanisms underlying risk of colorectal cancer from smoking and red/processed meat carcinogens by modeling exposure in normal colon organoids Research Paper

Matthew Devall, Christopher H. Dampier, Stephen Eaton, Mourad W. Ali, Virginia Díez-Obrero, Ferran Moratalla-Navarro, Jennifer Bryant, Lucas T. Jennelle, Victor Moreno, Steven M. Powell, Ulrike Peters, Graham Casey

Published Aug 18, 2021 · Vol. 12, No. 19 · pp. 1863-1877

Keywords: colon organoids, microsatellite instability, smoking, single-cell deconvolution, weighted gene co-expression network analysis

Nanoparticle T cell engagers for the treatment of acute myeloid leukemia Research Paper

Kinan Alhallak, Jennifer Sun, Barbara Muz, Amanda Jeske, Jessica Yavner, Hannah Bash, Chaelee Park, Berit Lubben, Ola Adebayo, Samuel Achilefu, John F. DiPersio, Abdel Kareem Azab

Published Aug 18, 2021 · Vol. 12, No. 19 · pp. 1878-1885

Keywords: acute myeloid leukemia, T cell engagers, nanoparticles, 3D tissue culture model

Correction: Lung cancer stem cells and their aggressive progeny, controlled by EGFR/MIG6 inverse expression, dictate a novel NSCLC treatment approach Correction

Zhiguang Xiao, Bianca Sperl, Silvia Gärtner, Tatiana Nedelko, Elvira Stacher-Priehse, Axel Ullrich, Pjotr G. Knyazev

Published Aug 14, 2021 · Vol. 12, No. 17 · pp. 1734-1735

Abstract_headers_test_v1_The use of a uPAR-targeted probe for photothermal cancer therapy prolongs survival in a xenograft mouse model of glioblastoma Research Paper

Marina Simón, Jesper Tranekjær Jørgensen, Karina Juhl, Andreas Kjaer

Published Aug 3, 2021

Keywords: photothermal therapy (PTT), indocyanine green (ICG), urokinase plasminogen activator receptor (uPAR), cancer, hyperthermia

The protective role of prolyl oligopeptidase (POP) inhibition in acute lung injury induced by intestinal ischemia-reperfusion Research Paper

Giovanna Casili, Sarah Adriana Scuderi, Marika Lanza, Alessia Filippone, Rossella Basilotta, Deborah Mannino, Michela Campolo, Emanuela Esposito, Irene Paterniti

Published Jul 31, 2021 · Vol. 12, No. 17 · pp. 1663-1676

Keywords: intestinal ischemia reperfusion (II/R), acute lung injury (ALI), prolyl oligopeptidase (POP), inflammation, angiogenesis

Interactions of multidomain pro-apoptotic and anti-apoptotic proteins in cancer cell death Review

Alexander Chota, Blassan P. George, Heidi Abrahamse

Published Jul 19, 2021 · Vol. 12, No. 16 · pp. 1615-1626

Keywords: apoptosis, caspases, cancer, Bcl-2 family proteins, p53

Neddylation and anti-tumor immunity Research Perspective

Xiaoguang Wang, Scott Best, Alexey V. Danilov

Published Jun 27, 2021 · Vol. 12, No. 21 · pp. 2227-2230

Keywords: neddylation, T cell, pevonedistat

Prokineticin-1 induces normal lymphangiogenic activity and is involved in lymphangiogenesis and lymph node metastasis in colorectal cancer Research Paper

Takayuki Naruse, Takanori Goi, Akio Yamaguchi

Published Jun 23, 2021 · Vol. 12, No. 14 · pp. 1388-1397

Keywords: prokineticin-1, lymphangiogenic activity, colorectal cancer

Genetic testing for homologous recombination repair (HRR) in metastatic castration-resistant prostate cancer (mCRPC): challenges and solutions Review

Rodney J. Scott, Anurag Mehta, Gabriel S. Macedo, Pavel S. Borisov, Ravindran Kanesvaran, Wafaa El Metnawy

Published Jun 22, 2021 · Vol. 12, No. 16 · pp. 1600-1614

Keywords: metastatic castration-resistant prostate cancer, homologous recombination repair, next generation sequencing, genetic testing

Eltrombopag and its iron chelating properties in pediatric acute myeloid leukemia Research Paper

Maura Argenziano, Chiara Tortora, Alessandra Di Paola, Elvira Pota, Martina Di Martino, Daniela Di Pinto, Caterina Di Leva, Francesca Rossi

Published Jun 16, 2021 · Vol. 12, No. 14 · pp. 1377-1387

Keywords: acute monocytic leukemia, eltrombopag, deferasirox, iron chelation, cancer

Cross-talks in colon cancer between RAGE/AGEs axis and inflammation/immunotherapy Review

Annachiara Mollace, Maria Laura Coluccio, Giuseppe Donato, Vincenzo Mollace, Natalia Malara

Published Jun 9, 2021 · Vol. 12, No. 13 · pp. 1281-1295

Keywords: RAGE, AGEs, colon cancer, microenvironment, Warburg effect

Ras-p53 genomic cooperativity as a model to investigate mechanisms of innate immune regulation in gastrointestinal cancers Research Perspective

Austin R. Dosch, Walid K. Chatila, Yuguang Ban, Anna Bianchi, Nilesh U. Deshpande, Iago De Castro Silva, Nipun B. Merchant, Jashodeep Datta

Published Jun 1, 2021 · Vol. 12, No. 20 · pp. 2104-2110

Keywords: Ras-p53 cooperativity, Ras, TP53, immune, gastrointestinal cancer

Deep learning with deep convolutional neural network using FDG-PET/CT for malignant pleural mesothelioma diagnosis Research Paper

Kazuhiro Kitajima, Hidetoshi Matsuo, Atsushi Kono, Kozo Kuribayashi, Takashi Kijima, Masaki Hashimoto, Seiki Hasegawa, Takamichi Murakami, Koichiro Yamakado

Published May 21, 2021 · Vol. 12, No. 12 · pp. 1187-1196

Keywords: mesothelioma, artificial intelligence, deep learning, FDG (fluorodeoxyglucose), PET-CT (positron emission tomography-computed tomography)

Genomic clustering analysis identifies molecular subtypes of thymic epithelial tumors independent of World Health Organization histologic type Research Paper

Sukhmani K. Padda, Yesim Gökmen-Polar, Jessica A. Hellyer, Sunil S. Badve, Neeraj K. Singh, Sumanth M. Vasista, Kabya Basu, Ansu Kumar, Heather A. Wakelee

Published May 21, 2021 · Vol. 12, No. 12 · pp. 1178-1186

Keywords: thymic epithelial tumor, thymoma, genomics, clustering, computational analysis

Role for Fgr and Numb in retinoic acid-induced differentiation and G0 arrest of non-APL AML cells Research Paper

Noor Kazim, Andrew Yen

Published May 11, 2021 · Vol. 12, No. 12 · pp. 1147-1164

Keywords: retinoic acid(RA), FGR, Numb, non-APL AML, cell differentiation

LY6 gene family presents a novel class of potential biomarkers associated with overall survival outcome of pancreatic ductal adenocarcinoma News

Claudia Gravekamp

Published May 8, 2021 · Vol. 12, No. 12 · pp. 1122-1123

Keywords: LY6 gene family, pancreatic ductal adenocarcinoma, bio marker, immune cell infiltrate

A novel E2F1-regulated lncRNA, LAPAS1, is required for S phase progression and cell proliferation Research Paper

Esther Baruch, Tali Nizri-Megnaji, Oron Berkowitz, Doron Ginsberg

Published May 7, 2021 · Vol. 12, No. 11 · pp. 1072-1082

Keywords: lncRNA, E2F, cell cycle, cell proliferation

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Pan-drug and drug-specific mechanisms of 5-FU, irinotecan (CPT-11), oxaliplatin, and cisplatin identified by comparison of transcriptomic and cytokine responses of colorectal cancer cells Research Paper

Polyclonal on- and off-target resistance mutations in an EML4-ALK positive non-small cell lung cancer patient under ALK inhibition Case Report

Correction: Antitumor activity of S116836, a novel tyrosine kinase inhibitor, against imatinib-resistant FIP1L1-PDGFRα-expressing cells Correction

Novel insights into the molecular mechanisms underlying risk of colorectal cancer from smoking and red/processed meat carcinogens by modeling exposure in normal colon organoids Research Paper

Nanoparticle T cell engagers for the treatment of acute myeloid leukemia Research Paper

Correction: Lung cancer stem cells and their aggressive progeny, controlled by EGFR/MIG6 inverse expression, dictate a novel NSCLC treatment approach Correction

Abstract_headers_test_v1_The use of a uPAR-targeted probe for photothermal cancer therapy prolongs survival in a xenograft mouse model of glioblastoma Research Paper

The protective role of prolyl oligopeptidase (POP) inhibition in acute lung injury induced by intestinal ischemia-reperfusion Research Paper

Interactions of multidomain pro-apoptotic and anti-apoptotic proteins in cancer cell death Review

Neddylation and anti-tumor immunity Research Perspective

Prokineticin-1 induces normal lymphangiogenic activity and is involved in lymphangiogenesis and lymph node metastasis in colorectal cancer Research Paper

Genetic testing for homologous recombination repair (HRR) in metastatic castration-resistant prostate cancer (mCRPC): challenges and solutions Review

Eltrombopag and its iron chelating properties in pediatric acute myeloid leukemia Research Paper

Cross-talks in colon cancer between RAGE/AGEs axis and inflammation/immunotherapy Review

Ras-p53 genomic cooperativity as a model to investigate mechanisms of innate immune regulation in gastrointestinal cancers Research Perspective

Deep learning with deep convolutional neural network using FDG-PET/CT for malignant pleural mesothelioma diagnosis Research Paper

Genomic clustering analysis identifies molecular subtypes of thymic epithelial tumors independent of World Health Organization histologic type Research Paper

Role for Fgr and Numb in retinoic acid-induced differentiation and G0 arrest of non-APL AML cells Research Paper

LY6 gene family presents a novel class of potential biomarkers associated with overall survival outcome of pancreatic ductal adenocarcinoma News

A novel E2F1-regulated lncRNA, LAPAS1, is required for S phase progression and cell proliferation Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Pan-drug and drug-specific mechanisms of 5-FU, irinotecan (CPT-11), oxaliplatin, and cisplatin identified by comparison of transcriptomic and cytokine responses of colorectal cancer cells Research Paper

Polyclonal on- and off-target resistance mutations in an EML4-ALK positive non-small cell lung cancer patient under ALK inhibition Case Report

Correction: Antitumor activity of S116836, a novel tyrosine kinase inhibitor, against imatinib-resistant FIP1L1-PDGFRα-expressing cells Correction

Novel insights into the molecular mechanisms underlying risk of colorectal cancer from smoking and red/processed meat carcinogens by modeling exposure in normal colon organoids Research Paper

Nanoparticle T cell engagers for the treatment of acute myeloid leukemia Research Paper

Correction: Lung cancer stem cells and their aggressive progeny, controlled by EGFR/MIG6 inverse expression, dictate a novel NSCLC treatment approach Correction

Abstract_headers_test_v1_The use of a uPAR-targeted probe for photothermal cancer therapy prolongs survival in a xenograft mouse model of glioblastoma Research Paper

The protective role of prolyl oligopeptidase (POP) inhibition in acute lung injury induced by intestinal ischemia-reperfusion Research Paper

Interactions of multidomain pro-apoptotic and anti-apoptotic proteins in cancer cell death Review

Neddylation and anti-tumor immunity Research Perspective

Prokineticin-1 induces normal lymphangiogenic activity and is involved in lymphangiogenesis and lymph node metastasis in colorectal cancer Research Paper

Genetic testing for homologous recombination repair (HRR) in metastatic castration-resistant prostate cancer (mCRPC): challenges and solutions Review

Eltrombopag and its iron chelating properties in pediatric acute myeloid leukemia Research Paper

Cross-talks in colon cancer between RAGE/AGEs axis and inflammation/immunotherapy Review

Ras-p53 genomic cooperativity as a model to investigate mechanisms of innate immune regulation in gastrointestinal cancers Research Perspective

Deep learning with deep convolutional neural network using FDG-PET/CT for malignant pleural mesothelioma diagnosis Research Paper

Genomic clustering analysis identifies molecular subtypes of thymic epithelial tumors independent of World Health Organization histologic type Research Paper

Role for Fgr and Numb in retinoic acid-induced differentiation and G0 arrest of non-APL AML cells Research Paper

LY6 gene family presents a novel class of potential biomarkers associated with overall survival outcome of pancreatic ductal adenocarcinoma News

A novel E2F1-regulated lncRNA, LAPAS1, is required for S phase progression and cell proliferation Research Paper