The Oncosearch | Oncotarget

Methylation of a newly identified region of the INS-IGF2 gene determines IGF2 expression in breast cancer tumors and in breast cancer cells Research Paper

Vinodh Kumar Radhakrishnan, Kameswaran Ravichandran, Chibuzo Eke, Amanda Ortiz-Vicil, Qianwei Tan, Marino De León, Daisy D. De León

Published Jun 13, 2020 · Vol. 11, No. 44 · pp. 3904-3920

Keywords: IGF2, INS-IGF2, hypermethylation, DMR, epigenetics

Lipid and protein tumor markers for head and neck squamous cell carcinoma identified by imaging mass spectrometry Research Paper

Janos Schmidt, Béla Kajtár, Kata Juhász, Mária Péter, Tamás Járai, András Burián, László Kereskai, Imre Gerlinger, Tamás Tornóczki, Gábor Balogh, László Vígh, Lászó Márk, Zsolt Balogi

Published Jun 11, 2020 · Vol. 11, No. 28 · pp. 2702-2717

Keywords: Imaging mass spectrometry, tumor marker, lipid tumor marker, S100A8, S100A9

Development and comprehensive characterization of porcine hepatocellular carcinoma for translational liver cancer investigation Research Paper

Ron C. Gaba, Lobna Elkhadragy, F. Edward Boas, Sulalita Chaki, Hanna H. Chen, Mohammed El-Kebir, Kelly D. Garcia, Eileena F. Giurini, Grace Guzman, Francesca V. LoBianco, Mario F. Neto, Jordan L. Newson, Aisha Qazi, Maureen Regan, Lauretta A. Rund, Regina M. Schwind, Matthew C. Stewart, Faith M. Thomas, Herbert E. Whiteley, Jiaqi Wu, Lawrence B. Schook, Kyle M. Schachtschneider

Published Jun 10, 2020 · Vol. 11, No. 28 · pp. 2686-2701

Keywords: liver cancer, transgenic pigs, large animal model, interventional radiology, personalized medicine

MYC’xing it up: zebrafish B ALL models provide insight into MYC-driven disease and relapse News

Diana Sá da Bandeira, Wilson K. Clements

Published Jun 9, 2020 · Vol. 11, No. 25 · pp. 2372-2374

Keywords: zebrafish, leukemia, B ALL, MYC, relapse

Mutation profile of primary subungual melanomas in Caucasians Research Paper

Aneta Borkowska, Anna Szumera-Ciećkiewicz, Mateusz Spałek, Paweł Teterycz, Anna Czarnecka, Artur Kowalik, Piotr Rutkowski

Published Jun 8, 2020 · Vol. 11, No. 25 · pp. 2404-2413

Keywords: melanoma, acral melanoma, subungual melanoma, nail apparatus melanoma, SMAD4

Lineage-restricted sympathoadrenal progenitors confer neuroblastoma origin and its tumorigenicity Research Paper

Chia-Lung Yang, André Serra-Roma, Marco Gualandi, Nicole Bodmer, Felix Niggli, Johannes Hubertus Schulte, Peter Karl Bode, Olga Shakhova

Published May 30, 2020 · Vol. 11, No. 24 · pp. 2357-2371

Keywords: neuroblastoma, neural crest stem cells, sox geness

RSK inhibitor BI-D1870 inhibits acute myeloid leukemia cell proliferation by targeting mitotic exit Research Paper

Hee-Don Chae, Ritika Dutta, Bruce Tiu, Fieke W. Hoff, Benedetta Accordi, Valentina Serafin, Minyoung Youn, Min Huang, Nathan Sumarsono, Kara L. Davis, Norman J. Lacayo, Martina Pigazzi, Terzah M. Horton, Steven M. Kornblau, Kathleen M. Sakamoto

Published May 26, 2020 · Vol. 11, No. 25 · pp. 2387-2403

Keywords: acute myeloid leukemia, BI-D1870, RSK, vincristine, spindle assembly checkpoint

IQGAP1 control of centrosome function defines distinct variants of triple negative breast cancer Research Paper

Mahasin A. Osman, William James Antonisamy, Evgeny Yakirevich

Published May 24, 2020 · Vol. 11, No. 26 · pp. 2493-2511

Keywords: IQGAP1, BRCA1, β-catenin, MNK1, triple negative breast cancer

The role of miRNA-133b and its target gene SIRT1 in FAP-derived desmoid tumor Research Paper

Maria Teresa Rotelli, Maria Grazia Refolo, Catia Lippolis, Aldo Cavallini, Arcangelo Picciariello, Domenico Piscitelli, Donato Francesco Altomare

Published May 24, 2020 · Vol. 11, No. 26 · pp. 2484-2492

Keywords: desmoid tumor, miRNA, familial adenomatous polyposis, B-catenin, Wnt pathway

miR-708-5p targets oncogenic prostaglandin E2 production to suppress a pro-tumorigenic phenotype in lung cancer cells Research Paper

Nicholas J. Monteleone, Carol S. Lutz

Published May 22, 2020 · Vol. 11, No. 26 · pp. 2464-2483

Keywords: miR-708-5p, miR-708, lung cancer, COX-2, mPGES-1

Development and characterization of the novel human osteosarcoma cell line COS-33 with sustained activation of the mTOR pathway Research Paper

Ashley VanCleave, Mykayla Palmer, Fang Fang, Haydee Torres, Tania Rodezno, Qilin Li, Kirby Fuglsby, Claire Evans, Yohannes Afeworki, Alan Ross, Pulivarthi Rao, Patricia Leiferman, Siyuan Zheng, Peter Houghton, Jianning Tao

Published May 18, 2020 · Vol. 11, No. 27 · pp. 2597-2610

Keywords: osteosarcoma, COS-33, mTOR, osteogenic differentiation, TP53

BCATc modulates crosstalk between the PI3K/Akt and the Ras/ERK pathway regulating proliferation in triple negative breast cancer Research Paper

Mai Ahmed Shafei, Thomas Forshaw, Jasmine Davis, Arwa Flemban, David Qualtrough, Sarah Dean, Claire Perks, Ming Dong, Robert Newman, Myra Elizabeth Conway

Published May 8, 2020 · Vol. 11, No. 21 · pp. 1971-1987

Keywords: BCAT, PI3K-AKT, ERK, breast cancer

TAK1 regulates the tumor microenvironment through inflammatory, angiogenetic and apoptotic signaling cascades Research Paper

Scott A. Scarneo, Kelly W. Yang, Jose R. Roques, Alanna Dai, Liesl S. Eibschutz, Philip Hughes, Timothy A.J. Haystead

Published May 8, 2020 · Vol. 11, No. 21 · pp. 1961-1970

Keywords: TAK1, breast cancer, therapeutic, inflammation

Inhibition of HAS2 and hyaluronic acid production by 1,25-Dihydroxyvitamin D₃ in breast cancer Research Paper

Carmen J. Narvaez, Erika LaPorta, Samantha Robilotto, Jennifer Liang, JoEllen Welsh

Published Apr 25, 2020 · Vol. 11, No. 30 · pp. 2889-2905

Keywords: vitamin D, hyaluronic acid, hyaluronan synthase, HAS2, breast cancer

Nutlin-3a suppresses poly (ADP-ribose) polymerase 1 by mechanisms different from conventional PARP1 suppressors in a human breast cancer cell line Research Paper

Masaki Kobayashi, Yuka Ishizaki, Mika Owaki, Yoko Matsumoto, Yuri Kakiyama, Shunsuke Hoshino, Ryoma Tagawa, Yuka Sudo, Naoyuki Okita, Kazunori Akimoto, Yoshikazu Higami

Published Apr 22, 2020 · Vol. 11, No. 18 · pp. 1653-1665

Keywords: nutlin-3a, PARP1, breast cancer, proteasomal degradation, autoPARylation

Characterization of GRK5 as a novel regulator of rhabdomyosarcoma tumor cell growth and self-renewal Research Paper

Thao Pham, Kristin Robinson, Terra Vleeshouwer-Neumann, James E. Annis, Eleanor Y. Chen

Published Apr 21, 2020 · Vol. 11, No. 16 · pp. 1448-1461

Keywords: rhabdomyosarcoma, self-renewal, GRK5, kinase, cell cycle

Knock-down of the TIM/TIPIN complex promotes apoptosis in melanoma cells Research Paper

Abhijit Chakraborty, Faisal Aziz, Eunmiri Roh, Le Thi My Le, Raja Dey, Tianshun Zhang, Moeez G. Rathore, Aalekhya Sharma Biswas, Ann M. Bode, Zigang Dong

Published Apr 17, 2020 · Vol. 11, No. 20 · pp. 1846-1861

Keywords: TIMELESS, TIPIN, apoptosis, xenograft, Cryo-EM

A 3D biofabricated cutaneous squamous cell carcinoma tissue model with multi-channel confocal microscopy imaging biomarkers to quantify antitumor effects of chemotherapeutics in tissue Research Paper

James R. Browning, Paige Derr, Kristy Derr, Nicole Doudican, Sam Michael, Samantha R. Lish, Nicholas A. Taylor, James G. Krueger, Marc Ferrer, John A. Carucci, Daniel S. Gareau

Published Apr 16, 2020 · Vol. 11, No. 27 · pp. 2587-2596

Keywords: squamous cell carcinoma, screening, 3D printing, in vitro model, confocal microscopy

Superior cancer preventive efficacy of low versus high dose of mTOR inhibitor in a mouse model of prostate cancer Research Paper

Marina P. Antoch, Michelle Wrobel, Bryan Gillard, Karen K. Kuropatwinski, Ilia Toshkov, Anatoli S. Gleiberman, Ellen Karasik, Michael T. Moser, Barbara A. Foster, Ekaterina L. Andrianova, Olga V. Chernova, Andrei V. Gudkov

Published Apr 14, 2020 · Vol. 11, No. 15 · pp. 1373-1387

Keywords: prostate cancer, rapamycin, prevention, mTOR, PTEN

Novel plant microRNAs from broccoletti sprouts do not show cross-kingdom regulation of pancreatic cancer Research Paper

Xi Xiao, Carsten Sticht, Libo Yin, Li Liu, Svetlana Karakhanova, Yefeng Yin, Christina Georgikou, Jury Gladkich, Wolfgang Gross, Norbert Gretz, Ingrid Herr

Published Apr 7, 2020 · Vol. 11, No. 14 · pp. 1203-1217

Keywords: broccoli, broccoletti, Brassica rapa sylvestris, plant microRNAs, cross-kingdom regulation

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Methylation of a newly identified region of the INS-IGF2 gene determines IGF2 expression in breast cancer tumors and in breast cancer cells Research Paper

Lipid and protein tumor markers for head and neck squamous cell carcinoma identified by imaging mass spectrometry Research Paper

Development and comprehensive characterization of porcine hepatocellular carcinoma for translational liver cancer investigation Research Paper

MYC’xing it up: zebrafish B ALL models provide insight into MYC-driven disease and relapse News

Mutation profile of primary subungual melanomas in Caucasians Research Paper

Lineage-restricted sympathoadrenal progenitors confer neuroblastoma origin and its tumorigenicity Research Paper

RSK inhibitor BI-D1870 inhibits acute myeloid leukemia cell proliferation by targeting mitotic exit Research Paper

IQGAP1 control of centrosome function defines distinct variants of triple negative breast cancer Research Paper

The role of miRNA-133b and its target gene SIRT1 in FAP-derived desmoid tumor Research Paper

miR-708-5p targets oncogenic prostaglandin E2 production to suppress a pro-tumorigenic phenotype in lung cancer cells Research Paper

Development and characterization of the novel human osteosarcoma cell line COS-33 with sustained activation of the mTOR pathway Research Paper

BCATc modulates crosstalk between the PI3K/Akt and the Ras/ERK pathway regulating proliferation in triple negative breast cancer Research Paper

TAK1 regulates the tumor microenvironment through inflammatory, angiogenetic and apoptotic signaling cascades Research Paper

Inhibition of HAS2 and hyaluronic acid production by 1,25-Dihydroxyvitamin D₃ in breast cancer Research Paper

Nutlin-3a suppresses poly (ADP-ribose) polymerase 1 by mechanisms different from conventional PARP1 suppressors in a human breast cancer cell line Research Paper

Characterization of GRK5 as a novel regulator of rhabdomyosarcoma tumor cell growth and self-renewal Research Paper

Knock-down of the TIM/TIPIN complex promotes apoptosis in melanoma cells Research Paper

A 3D biofabricated cutaneous squamous cell carcinoma tissue model with multi-channel confocal microscopy imaging biomarkers to quantify antitumor effects of chemotherapeutics in tissue Research Paper

Superior cancer preventive efficacy of low versus high dose of mTOR inhibitor in a mouse model of prostate cancer Research Paper

Novel plant microRNAs from broccoletti sprouts do not show cross-kingdom regulation of pancreatic cancer Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Methylation of a newly identified region of the INS-IGF2 gene determines IGF2 expression in breast cancer tumors and in breast cancer cells Research Paper

Lipid and protein tumor markers for head and neck squamous cell carcinoma identified by imaging mass spectrometry Research Paper

Development and comprehensive characterization of porcine hepatocellular carcinoma for translational liver cancer investigation Research Paper

MYC’xing it up: zebrafish B ALL models provide insight into MYC-driven disease and relapse News

Mutation profile of primary subungual melanomas in Caucasians Research Paper

Lineage-restricted sympathoadrenal progenitors confer neuroblastoma origin and its tumorigenicity Research Paper

RSK inhibitor BI-D1870 inhibits acute myeloid leukemia cell proliferation by targeting mitotic exit Research Paper

IQGAP1 control of centrosome function defines distinct variants of triple negative breast cancer Research Paper

The role of miRNA-133b and its target gene SIRT1 in FAP-derived desmoid tumor Research Paper

miR-708-5p targets oncogenic prostaglandin E2 production to suppress a pro-tumorigenic phenotype in lung cancer cells Research Paper

Development and characterization of the novel human osteosarcoma cell line COS-33 with sustained activation of the mTOR pathway Research Paper

BCATc modulates crosstalk between the PI3K/Akt and the Ras/ERK pathway regulating proliferation in triple negative breast cancer Research Paper

TAK1 regulates the tumor microenvironment through inflammatory, angiogenetic and apoptotic signaling cascades Research Paper

Inhibition of HAS2 and hyaluronic acid production by 1,25-Dihydroxyvitamin D3 in breast cancer Research Paper

Nutlin-3a suppresses poly (ADP-ribose) polymerase 1 by mechanisms different from conventional PARP1 suppressors in a human breast cancer cell line Research Paper

Characterization of GRK5 as a novel regulator of rhabdomyosarcoma tumor cell growth and self-renewal Research Paper

Knock-down of the TIM/TIPIN complex promotes apoptosis in melanoma cells Research Paper

A 3D biofabricated cutaneous squamous cell carcinoma tissue model with multi-channel confocal microscopy imaging biomarkers to quantify antitumor effects of chemotherapeutics in tissue Research Paper

Superior cancer preventive efficacy of low versus high dose of mTOR inhibitor in a mouse model of prostate cancer Research Paper

Novel plant microRNAs from broccoletti sprouts do not show cross-kingdom regulation of pancreatic cancer Research Paper

Inhibition of HAS2 and hyaluronic acid production by 1,25-Dihydroxyvitamin D₃ in breast cancer Research Paper