The Oncosearch | Oncotarget

Identification of lung cancer drivers by comparison of the observed and the expected numbers of missense and nonsense mutations in individual human genes Research Paper

Olga Y. Gorlova, Marek Kimmel, Spiridon Tsavachidis, Christopher I. Amos, Ivan P. Gorlov

Published May 6, 2022 · Vol. 13, No. 1 · pp. 756-767

Keywords: lung cancer, somatic mutations, driver genes, Catalog Of Somatic Mutations In Cancer (COSMIC)

Combined treatment with niclosamide and camptothecin enhances anticancer effect in U87 MG human glioblastoma cells Research Paper

Laura Valdez, Benxu Cheng, Daniela Gonzalez, Reanna Rodriguez, Paola Campano, Andrew Tsin, Xiaoqian Fang

Published Apr 22, 2022 · Vol. 13, No. 1 · pp. 642-658

Keywords: glioblastoma, niclosamide, camptothecin, cancer, chemotherapy

A novel group of genes that cause endocrine resistance in breast cancer identified by dynamic gene expression analysis Research Paper

Arvand Asghari, Katherine Wall, Michael Gill, Natascha Del Vecchio, Farnaz Allahbakhsh, Jacky Wu, Nan Deng, W. Jim Zheng, Hulin Wu, Michihisa Umetani, Vahed Maroufy

Published Mar 29, 2022 · Vol. 13, No. 1 · pp. 600-613

Keywords: breast cancer, triple negative breast cancer, gene expression profiling, endocrine resistance, gene clustering

Role of the prorenin receptor in endometrial cancer cell growth Research Paper

Jacinta H. Martin, Riazuddin Mohammed, Sarah J. Delforce, David A. Skerrett-Byrne, Celine Corbisier de Meaultsart, Juhura G. Almazi, Andrew N. Stephens, Nicole M. Verrills, Evdokia Dimitriadis, Yu Wang, Eugenie R. Lumbers, Kirsty G. Pringle

Published Mar 23, 2022 · Vol. 13, No. 1 · pp. 587-599

Keywords: (P)RR, ATP6AP2, endometrial cancer, cellular viability, cellular proliferation

MYH9 binds to dNTPs via deoxyribose moiety and plays an important role in DNA synthesis Research Paper

Pratima Nangia-Makker, Malathy P.V. Shekhar, Victor Hogan, Vitaly Balan, Avraham Raz

Published Mar 9, 2022 · Vol. 13, No. 1 · pp. 534-550

Keywords: myosin II, MYH9, dNTP, deoxyribose-5-phosphate, DNA synthesis

Correction: PINK1 suppresses alpha-synuclein-induced neuronal injury: a novel mechanism in protein phosphatase 2A activation Correction

Weiwei Yang, Xue Wang, Jia Liu, Chunli Duan, Ge Gao, Lingling Lu, Shun Yu, Hui Yang

Published Mar 8, 2022

NOTCH1 PEST domain variants are responsive to standard of care treatments despite distinct transformative properties in a breast cancer model Research Paper

Karen Cravero, Morgan V. Pantone, Dong Ho Shin, Riley Bergman, Rory Cochran, David Chu, Daniel J. Zabransky, Swathi Karthikeyan, Ian G. Waters, Natasha Hunter, D. Marc Rosen, Kelly Kyker-Snowman, W. Brian Dalton, Berry Button, Dan Shinn, Hong Yuen Wong, Joshua Donaldson, Paula J. Hurley, Sarah Croessmann, Ben Ho Park

Published Feb 11, 2022 · Vol. 13, No. 1 · pp. 373-386

Keywords: NOTCH1, TNBC, breast cancer, PEST

ABT199/venetoclax potentiates the cytotoxicity of alkylating agents and fludarabine in acute myeloid leukemia cells Research Paper

Benigno C. Valdez, David Murray, Bin Yuan, Yago Nieto, Uday Popat, Borje S. Andersson

Published Feb 2, 2022 · Vol. 13, No. 1 · pp. 319-330

Keywords: ABT199/venetoclax, busulfan, cyclophosphamide, fludarabine, acute myeloid leukemia

The long winding road to the safer glucocorticoid receptor (GR) targeting therapies Review

Ekaterina A. Lesovaya, Daria Chudakova, Gleb Baida, Ekaterina M. Zhidkova, Kirill I. Kirsanov, Marianna G. Yakubovskaya, Irina V. Budunova

Published Feb 1, 2022 · Vol. 13, No. 1 · pp. 408-424

Keywords: glucocorticoid receptor, glucocorticoids, SEGRAM, REDD1, drug repurposing

PACER lncRNA regulates COX-2 expression in lung cancer cells Research Paper

Samuel Z. Desind, Joseph R. Iacona, Christina Y. Yu, Antonina Mitrofanova, Carol S. Lutz

Published Jan 29, 2022 · Vol. 13, No. 1 · pp. 291-306

Keywords: PACER, COX-2, PGE₂, lung adenocarcinoma, inflammation

Common cancer treatments targeting DNA double strand breaks affect long-term memory and relate to immediate early gene expression in a sex-dependent manner Research Paper

Sydney Weber Boutros, Destine Krenik, Sarah Holden, Vivek K. Unni, Jacob Raber

Published Jan 14, 2022 · Vol. 13, No. 1 · pp. 198-213

Keywords: amifostine, etoposide, double strand breaks, memory, sex

Exploiting protein family and protein network data to identify novel drug targets for bladder cancer Research Paper

Tolulope Tosin Adeyelu, Aurelio A. Moya-Garcia, Christine Orengo

Published Dec 28, 2021 · Vol. 13, No. 1 · pp. 105-117

Keywords: CATH-FunFams, bladder cancer, protein interaction network, drug targets, drug side effects

Synthesis of a novel nanobioconjugate for targeted photodynamic therapy of colon cancer enhanced with cannabidiol Research Paper

Nkune Williams Nkune, Cherie Ann Kruger, Heidi Abrahamse

Published Dec 23, 2021 · Vol. 13, No. 1 · pp. 156-172

Keywords: cannabidiol, photodynamic therapy, colorectal cancer, nanoparticles, photosensitizer

Early detection of treatment futility in patients with metastatic colorectal cancer Research Paper

Jodi I. Rattner, Karen A. Kopciuk, Hans J. Vogel, Patricia A. Tang, Jeremy D. Shapiro, Dongsheng Tu, Derek J. Jonker, Lillian L. Siu, Chris J. O’Callaghan, Oliver F. Bathe

Published Dec 21, 2021 · Vol. 13, No. 1 · pp. 61-72

Keywords: colorectal cancer, metabolomics, response biomarkers, radiographic imaging, chemotherapy

Comparative transcriptome analysis between patient and endometrial cancer cell lines to determine common signaling pathways and markers linked to cancer progression Research Paper

Madelaine J. Cho-Clark, Gauthaman Sukumar, Newton Medeiros Vidal, Sorana Raiciulescu, Mario G. Oyola, Cara Olsen, Leonardo Mariño-Ramírez, Clifton L. Dalgard, T. John Wu

Published Dec 16, 2021 · Vol. 12, No. 26 · pp. 2500-2513

Keywords: endometrial cancer, cancer stage, comparative transcriptome analysis, signaling pathways, normalization

RASAL2 suppresses the proliferative and invasive ability of PC3 prostate cancer cells Research Paper

Krishma Tailor, Joseph Paul, Somiranjan Ghosh, Namita Kumari, Bernard Kwabi-Addo

Published Dec 15, 2021 · Vol. 12, No. 26 · pp. 2489-2499

Keywords: RASAL2, Ras-protooncogene, prostate cancer, TNFα signal, DNA methylation

Correction: Novel Akt activator SC-79 is a potential treatment for alcohol-induced osteonecrosis of the femoral head Correction

Yi-Xuan Chen, Shi-Cong Tao, Zheng-Liang Xu, Wen-Jing Yin, Yue-Lei Zhang, Jun-Hui Yin, You-Shui Gao, Chang-Qing Zhang

Published Nov 5, 2021

Correction: Lipolysis-stimulated lipoprotein receptor overexpression is a novel predictor of poor clinical prognosis and a potential therapeutic target in gastric cancer Correction

Takahito Sugase, Tsuyoshi Takahashi, Satoshi Serada, Minoru Fujimoto, Tomoharu Ohkawara, Kosuke Hiramatsu, Masahiro Koh, Yurina Saito, Koji Tanaka, Yasuhiro Miyazaki, Tomoki Makino, Yukinori Kurokawa, Makoto Yamasaki, Kiyokazu Nakajima, Kazuhiro Hanazaki, Masaki Mori, Yuichiro Doki, Tetsuji Naka

Published Oct 12, 2021 · Vol. 12, No. 21 · pp. 2232-2233

Hyperprogression of a mismatch repair-deficient colon cancer in a humanized mouse model following administration of immune checkpoint inhibitor pembrolizumab Research Paper

Ilyas Sahin, Andrew George, Shengliang Zhang, Kelsey E. Huntington, Zehra Ordulu, Lanlan Zhou, Wafik S. El-Deiry

Published Sep 24, 2021 · Vol. 12, No. 21 · pp. 2131-2146

Keywords: cancer immunotherapy, immune checkpoint inhibitors, hyperprogressive disease (HPD), hyperprogression (HP), humanized mouse

Luminescence complementation technology for the identification of MYC:TRRAP inhibitors Research Paper

Edmond J. Feris, John W. Hinds, Michael D. Cole

Published Sep 11, 2021 · Vol. 12, No. 21 · pp. 2147-2157

Keywords: cancer, drug discovery, targeted therapy, oncogene, transcription factor

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

Identification of lung cancer drivers by comparison of the observed and the expected numbers of missense and nonsense mutations in individual human genes Research Paper

Combined treatment with niclosamide and camptothecin enhances anticancer effect in U87 MG human glioblastoma cells Research Paper

A novel group of genes that cause endocrine resistance in breast cancer identified by dynamic gene expression analysis Research Paper

Role of the prorenin receptor in endometrial cancer cell growth Research Paper

MYH9 binds to dNTPs via deoxyribose moiety and plays an important role in DNA synthesis Research Paper

Correction: PINK1 suppresses alpha-synuclein-induced neuronal injury: a novel mechanism in protein phosphatase 2A activation Correction

NOTCH1 PEST domain variants are responsive to standard of care treatments despite distinct transformative properties in a breast cancer model Research Paper

ABT199/venetoclax potentiates the cytotoxicity of alkylating agents and fludarabine in acute myeloid leukemia cells Research Paper

The long winding road to the safer glucocorticoid receptor (GR) targeting therapies Review

PACER lncRNA regulates COX-2 expression in lung cancer cells Research Paper

Common cancer treatments targeting DNA double strand breaks affect long-term memory and relate to immediate early gene expression in a sex-dependent manner Research Paper

Exploiting protein family and protein network data to identify novel drug targets for bladder cancer Research Paper

Synthesis of a novel nanobioconjugate for targeted photodynamic therapy of colon cancer enhanced with cannabidiol Research Paper

Early detection of treatment futility in patients with metastatic colorectal cancer Research Paper

Comparative transcriptome analysis between patient and endometrial cancer cell lines to determine common signaling pathways and markers linked to cancer progression Research Paper

RASAL2 suppresses the proliferative and invasive ability of PC3 prostate cancer cells Research Paper

Correction: Novel Akt activator SC-79 is a potential treatment for alcohol-induced osteonecrosis of the femoral head Correction

Correction: Lipolysis-stimulated lipoprotein receptor overexpression is a novel predictor of poor clinical prognosis and a potential therapeutic target in gastric cancer Correction

Hyperprogression of a mismatch repair-deficient colon cancer in a humanized mouse model following administration of immune checkpoint inhibitor pembrolizumab Research Paper

Luminescence complementation technology for the identification of MYC:TRRAP inhibitors Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Identification of lung cancer drivers by comparison of the observed and the expected numbers of missense and nonsense mutations in individual human genes Research Paper

Combined treatment with niclosamide and camptothecin enhances anticancer effect in U87 MG human glioblastoma cells Research Paper

A novel group of genes that cause endocrine resistance in breast cancer identified by dynamic gene expression analysis Research Paper

Role of the prorenin receptor in endometrial cancer cell growth Research Paper

MYH9 binds to dNTPs via deoxyribose moiety and plays an important role in DNA synthesis Research Paper

Correction: PINK1 suppresses alpha-synuclein-induced neuronal injury: a novel mechanism in protein phosphatase 2A activation Correction

NOTCH1 PEST domain variants are responsive to standard of care treatments despite distinct transformative properties in a breast cancer model Research Paper

ABT199/venetoclax potentiates the cytotoxicity of alkylating agents and fludarabine in acute myeloid leukemia cells Research Paper

The long winding road to the safer glucocorticoid receptor (GR) targeting therapies Review

PACER lncRNA regulates COX-2 expression in lung cancer cells Research Paper

Common cancer treatments targeting DNA double strand breaks affect long-term memory and relate to immediate early gene expression in a sex-dependent manner Research Paper

Exploiting protein family and protein network data to identify novel drug targets for bladder cancer Research Paper

Synthesis of a novel nanobioconjugate for targeted photodynamic therapy of colon cancer enhanced with cannabidiol Research Paper

Early detection of treatment futility in patients with metastatic colorectal cancer Research Paper

Comparative transcriptome analysis between patient and endometrial cancer cell lines to determine common signaling pathways and markers linked to cancer progression Research Paper

RASAL2 suppresses the proliferative and invasive ability of PC3 prostate cancer cells Research Paper

Correction: Novel Akt activator SC-79 is a potential treatment for alcohol-induced osteonecrosis of the femoral head Correction

Correction: Lipolysis-stimulated lipoprotein receptor overexpression is a novel predictor of poor clinical prognosis and a potential therapeutic target in gastric cancer Correction

Hyperprogression of a mismatch repair-deficient colon cancer in a humanized mouse model following administration of immune checkpoint inhibitor pembrolizumab Research Paper

Luminescence complementation technology for the identification of MYC:TRRAP inhibitors Research Paper