The Oncosearch | Oncotarget

Sequence conservation of mitochondrial (mt)DNA during expansion of clonal mammary epithelial populations suggests a common mtDNA template in CzechII mice Research Paper

Jabril R. Johnson, Justin B. Lack, Corinne A. Boulanger, Lauren E. Ragle, Gilbert H. Smith

Published Jan 14, 2020 · Vol. 11, No. 2 · pp. 161-174

Keywords: mitochondrial DNA, next-generation sequencing, clonal expansion, mammary cancer

Pathogenic mutations and overall survival in 3,084 patients with cancer: the Hellenic Cooperative Oncology Group Precision Medicine Initiative Research Paper

Elena Fountzilas, Vassiliki Kotoula, Georgia-Angeliki Koliou, Eleni Giannoulatou, Helen Gogas, Christos Papadimitriou, Ioannis Tikas, Jianhua Zhang, Kyriaki Papadopoulou, Flora Zagouri, Christos Christodoulou, Angelos Koutras, Thomas Makatsoris, Sofia Chrisafi, Helena Linardou, Ioannis Varthalitis, George Papatsibas, Evangelia Razis, Pavlos Papakostas, Epaminontas Samantas, Gerasimos Aravantinos, Dimitrios Bafaloukos, Paris Kosmidis, Anna Koumarianou, Amanda Psyrri, Georgios Pentheroudakis, Dimitrios Pectasides, Andrew Futreal, George Fountzilas, Apostolia M. Tsimberidou

Published Jan 7, 2020 · Vol. 11, No. 1 · pp. 1-14

Keywords: actionable gene, next-generation sequencing, pathogenic mutation, precision oncology, prognosis

The synergistic inhibitory effect of combining therapies targeting EGFR and mitochondria in sarcomas Research Paper

Xiaochun Wang, Reichelle X. Yeo, Philip J. Hogg, David Goldstein, Philip Crowe, Pierre J. Dilda, Jia-Lin Yang

Published Jan 7, 2020 · Vol. 11, No. 1 · pp. 46-61

Keywords: EGFR-targeted therapy, mitochondria inhibitor, tumour metabolism inhibition, sarcomas, combination therapy

Novel functional anti-HER3 monoclonal antibodies with potent anti-cancer effects on various human epithelial cancers Research Paper

Kouki Okita, Shogo Okazaki, Shinya Uejima, Erina Yamada, Hiroki Kaminaka, Misa Kondo, Shiho Ueda, Ryo Tokiwa, Nami Iwata, Akitaka Yamasaki, Natsumi Hayashi, Dai Ogura, Kenji Hirotani, Toshiaki Yoshioka, Masahiro Inoue, Kazue Masuko, Takashi Masuko

Published Jan 7, 2020 · Vol. 11, No. 1 · pp. 31-45

Keywords: CDR, HER3, internalization, mAb, NRG1

Targeting the non-canonical roles of PCNA modifies and increases the response to targeted anti-cancer therapy Research Paper

Caroline K. Søgaard, Anala Nepal, Voin Petrovic, Animesh Sharma, Nina-Beate Liabakk, Tonje S. Steigedal, Marit Otterlei

Published Dec 31, 2019 · Vol. 10, No. 68 · pp. 7185-7197

Keywords: APIM, multi-targeting therapy, signaling pathways, autophagy, cancer

Low-dose metronomic cyclophosphamide complements the actions of an intratumoral C-class CpG TLR9 agonist to potentiate innate immunity and drive potent T cell-mediated anti-tumor responses Research Paper

Weng In Leong, Rachel Y. Ames, Jessica M. Haverkamp, Laura Torres, Janine Kline, Ashil Bans, Lauren Rocha, Marilena Gallotta, Cristiana Guiducci, Robert L. Coffman, Mary J. Janatpour

Published Dec 31, 2019 · Vol. 10, No. 68 · pp. 7220-7237

Keywords: TLR9, SD-101, cyclophosphamide, immune therapy, innate immunity

Effects of neoadjuvant FOLFIRINOX and gemcitabine-based chemotherapy on cancer cell survival and death in patients with pancreatic ductal adenocarcinoma Research Paper

Li Xie, Leizhou Xia, Ulla Klaiber, Milena Sachsenmaier, Ulf Hinz, Frank Bergmann, Oliver Strobel, Markus W. Büchler, John P. Neoptolemos, Franco Fortunato, Thilo Hackert

Published Dec 31, 2019 · Vol. 10, No. 68 · pp. 7276-7287

Keywords: autophagy, cell death, stroma, neoadjuvant therapy, prognosis

Dysregulation of adenosine kinase isoforms in breast cancer Research Paper

Bahar Shamloo, Nandita Kumar, Randall H. Owen, Jesica Reemmer, John Ost, R. Serene Perkins, Hai-Ying Shen

Published Dec 31, 2019 · Vol. 10, No. 68 · pp. 7238-7250

Keywords: adenosine kinase, breast cancer, adenosine kinase isoforms, metastasis, proliferation

Head and neck squamous cancer progression is marked by CLIC4 attenuation in tumor epithelium and reciprocal stromal upregulation of miR-142-3p, a novel post-transcriptional regulator of CLIC4 Research Paper

Brandi L. Carofino, Kayla M. Dinshaw, Pui Yan Ho, Christophe Cataisson, Aleksandra M. Michalowski, Andrew Ryscavage, Addie Alkhas, Nathan W. Wong, Vishal Koparde, Stuart H. Yuspa

Published Dec 31, 2019 · Vol. 10, No. 68 · pp. 7251-7275

Keywords: in situ hybridization, single-cell RNA-sequencing, stroma, miRNA, immune infiltration

Prognostic value of immune cells in the tumor microenvironment of early-stage lung cancer: a meta-analysis Meta-Analysis

Stephanie Tuminello, Rajwanth Veluswamy, Wil Lieberman-Cribbin, Sacha Gnjatic, Francesca Petralia, Pei Wang, Raja Flores, Emanuela Taioli

Published Dec 24, 2019 · Vol. 10, No. 67 · pp. 7142-7155

Keywords: NSCLC, immune contexture, tumor microenvironment, TILs

Single cell correlation analysis of liquid and solid biopsies in metastatic colorectal cancer Research Paper

Anna S. Gerdtsson, Jana-Aletta Thiele, Stephanie N. Shishido, Serena Zheng, Randolph Schaffer, Kelly Bethel, Steven Curley, Heinz-Josef Lenz, Diana L. Hanna, Jorge Nieva, Anand Kolatkar, Carmen Ruiz, Mariam Rodriguez-Lee, Gerard J. Oakley III, Jerry S.H. Lee, James Hicks, Peter Kuhn

Published Dec 17, 2019 · Vol. 10, No. 66 · pp. 7016-7030

Keywords: single cell analysis, liquid biopsy, metastatic colorectal cancer, circulating tumor cells, cytomorphology

CRISPR/Cas9 genome-wide screening identifies KEAP1 as a sorafenib, lenvatinib, and regorafenib sensitivity gene in hepatocellular carcinoma Research Paper

Adi Zheng, Nadja Chevalier, Margot Calderoni, Gilles Dubuis, Olivier Dormond, Panos G. Ziros, Gerasimos P. Sykiotis, Christian Widmann

Published Dec 17, 2019 · Vol. 10, No. 66 · pp. 7058-7070

Keywords: KEAP1, sorafenib, hepatocellular carcinoma, lenvatinib, Regorafenib

EGFR806-CAR T cells selectively target a tumor-restricted EGFR epitope in glioblastoma Research Paper

Ali C. Ravanpay, Juliane Gust, Adam J. Johnson, Lisa S. Rolczynski, Michelle Cecchini, Cindy A. Chang, Virginia J. Hoglund, Rithun Mukherjee, Nicholas A. Vitanza, Rimas J. Orentas, Michael C. Jensen

Published Dec 17, 2019 · Vol. 10, No. 66 · pp. 7080-7095

Keywords: glioblastoma, CAR T cell, EGFR, immunotherapy, mAb806

IGFBP-2 acts as a tumour suppressor and plays a role in determining chemosensitivity in bladder cancer cells Research Paper

Zhen Tang, David Gillatt, Edward Rowe, Anthony Koupparis, Jeff M.P. Holly, Claire M. Perks

Published Dec 17, 2019 · Vol. 10, No. 66 · pp. 7043-7057

Keywords: IGFBP-2, methylation, chemosensitivity, invasion, bladder cancer

Effects of neoadjuvant FOLFIRONOX and gemcitabine-based chemotherapy on cancer cell survival and death in patients with pancreatic ductal adenocarcinoma Research Paper

Li Xie, Leizhou Xia, Ulla Klaiber, Milena Sachsenmaier, Ulf Hinz, Frank Bergmann, Oliver Strobel, Markus W. Büchler, John P. Neoptolemos, Franco Fortunato, Thilo Hackert

Published Dec 16, 2019

Keywords: autophagy, cell death, stroma, neoadjuvant therapy, prognosis

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

Wayne D. Blosser, Jack A. Dempsey, Ann M. Mc Nulty, Xi Rao, Philip J. Ebert, Caitlin D. Lowery, Philip W. Iversen, Yue Wang Webster, Gregory P. Donoho, Xueqian Gong, Farhana F. Merzoug, Sean Buchanan, Karsten Boehnke, Chunping Yu, Xin Tian You, Richard P. Beckmann, Wenjuan Wu, Samuel C. McNeely, Aimee Bence Lin, Ricardo Martinez

Published Dec 16, 2019

Keywords: CHK1, prexasertib, replication stress, replication fork, innate immunity

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

Wayne D. Blosser, Jack A. Dempsey, Ann M. Mc Nulty, Xi Rao, Philip J. Ebert, Caitlin D. Lowery, Philip W. Iversen, Yue Wang Webster, Gregory P. Donoho, Xueqian Gong, Farhana F. Merzoug, Sean Buchanan, Karsten Boehnke, Chunping Yu, Xin Tian You, Richard P. Beckmann, Wenjuan Wu, Samuel C. McNeely, Aimee Bence Lin, Ricardo Martinez

Published Dec 16, 2019

Keywords: CHK1, prexasertib, replication stress, replication fork, innate immunity

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

Wayne D. Blosser, Jack A. Dempsey, Ann M. Mc Nulty, Xi Rao, Philip J. Ebert, Caitlin D. Lowery, Philip W. Iversen, Yue Wang Webster, Gregory P. Donoho, Xueqian Gong, Farhana F. Merzoug, Sean Buchanan, Karsten Boehnke, Chunping Yu, Xin Tian You, Richard P. Beckmann, Wenjuan Wu, Samuel C. McNeely, Aimee Bence Lin, Ricardo Martinez

Published Dec 16, 2019

Keywords: CHK1, prexasertib, replication stress, replication fork, innate immunity

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

Wayne D. Blosser, Jack A. Dempsey, Ann M. Mc Nulty, Xi Rao, Philip J. Ebert, Caitlin D. Lowery, Philip W. Iversen, Yue Wang Webster, Gregory P. Donoho, Xueqian Gong, Farhana F. Merzoug, Sean Buchanan, Karsten Boehnke, Chunping Yu, Xin Tian You, Richard P. Beckmann, Wenjuan Wu, Samuel C. McNeely, Aimee Bence Lin, Ricardo Martinez

Published Dec 16, 2019

Keywords: CHK1, prexasertib, replication stress, replication fork, innate immunity

Correction: The novel long non-coding RNA TALNEC2, regulates tumor cell growth and the stemness and radiation response of glioma stem cells Correction

Shlomit Brodie, Hae Kyung Lee, Wei Jiang, Simona Cazacu, Cunli Xiang, Laila M. Poisson, Indrani Datta, Steve Kalkanis, Doron Ginsberg, Chaya Brodie

Published Dec 11, 2019 · Vol. 12, No. 26 · pp. 2546-2547

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Sequence conservation of mitochondrial (mt)DNA during expansion of clonal mammary epithelial populations suggests a common mtDNA template in CzechII mice Research Paper

Pathogenic mutations and overall survival in 3,084 patients with cancer: the Hellenic Cooperative Oncology Group Precision Medicine Initiative Research Paper

The synergistic inhibitory effect of combining therapies targeting EGFR and mitochondria in sarcomas Research Paper

Novel functional anti-HER3 monoclonal antibodies with potent anti-cancer effects on various human epithelial cancers Research Paper

Targeting the non-canonical roles of PCNA modifies and increases the response to targeted anti-cancer therapy Research Paper

Low-dose metronomic cyclophosphamide complements the actions of an intratumoral C-class CpG TLR9 agonist to potentiate innate immunity and drive potent T cell-mediated anti-tumor responses Research Paper

Effects of neoadjuvant FOLFIRINOX and gemcitabine-based chemotherapy on cancer cell survival and death in patients with pancreatic ductal adenocarcinoma Research Paper

Dysregulation of adenosine kinase isoforms in breast cancer Research Paper

Head and neck squamous cancer progression is marked by CLIC4 attenuation in tumor epithelium and reciprocal stromal upregulation of miR-142-3p, a novel post-transcriptional regulator of CLIC4 Research Paper

Prognostic value of immune cells in the tumor microenvironment of early-stage lung cancer: a meta-analysis Meta-Analysis

Single cell correlation analysis of liquid and solid biopsies in metastatic colorectal cancer Research Paper

CRISPR/Cas9 genome-wide screening identifies KEAP1 as a sorafenib, lenvatinib, and regorafenib sensitivity gene in hepatocellular carcinoma Research Paper

EGFR806-CAR T cells selectively target a tumor-restricted EGFR epitope in glioblastoma Research Paper

IGFBP-2 acts as a tumour suppressor and plays a role in determining chemosensitivity in bladder cancer cells Research Paper

Effects of neoadjuvant FOLFIRONOX and gemcitabine-based chemotherapy on cancer cell survival and death in patients with pancreatic ductal adenocarcinoma Research Paper

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

Correction: The novel long non-coding RNA TALNEC2, regulates tumor cell growth and the stemness and radiation response of glioma stem cells Correction

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Sequence conservation of mitochondrial (mt)DNA during expansion of clonal mammary epithelial populations suggests a common mtDNA template in CzechII mice Research Paper

Pathogenic mutations and overall survival in 3,084 patients with cancer: the Hellenic Cooperative Oncology Group Precision Medicine Initiative Research Paper

The synergistic inhibitory effect of combining therapies targeting EGFR and mitochondria in sarcomas Research Paper

Novel functional anti-HER3 monoclonal antibodies with potent anti-cancer effects on various human epithelial cancers Research Paper

Targeting the non-canonical roles of PCNA modifies and increases the response to targeted anti-cancer therapy Research Paper

Low-dose metronomic cyclophosphamide complements the actions of an intratumoral C-class CpG TLR9 agonist to potentiate innate immunity and drive potent T cell-mediated anti-tumor responses Research Paper

Effects of neoadjuvant FOLFIRINOX and gemcitabine-based chemotherapy on cancer cell survival and death in patients with pancreatic ductal adenocarcinoma Research Paper

Dysregulation of adenosine kinase isoforms in breast cancer Research Paper

Head and neck squamous cancer progression is marked by CLIC4 attenuation in tumor epithelium and reciprocal stromal upregulation of miR-142-3p, a novel post-transcriptional regulator of CLIC4 Research Paper

Prognostic value of immune cells in the tumor microenvironment of early-stage lung cancer: a meta-analysis Meta-Analysis

Single cell correlation analysis of liquid and solid biopsies in metastatic colorectal cancer Research Paper

CRISPR/Cas9 genome-wide screening identifies KEAP1 as a sorafenib, lenvatinib, and regorafenib sensitivity gene in hepatocellular carcinoma Research Paper

EGFR806-CAR T cells selectively target a tumor-restricted EGFR epitope in glioblastoma Research Paper

IGFBP-2 acts as a tumour suppressor and plays a role in determining chemosensitivity in bladder cancer cells Research Paper

Effects of neoadjuvant FOLFIRONOX and gemcitabine-based chemotherapy on cancer cell survival and death in patients with pancreatic ductal adenocarcinoma Research Paper

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

A pan-cancer transcriptome analysis identifies replication fork and innate immunity genes as modifiers of response to the CHK1 inhibitor prexasertib Research Paper

Correction: The novel long non-coding RNA TALNEC2, regulates tumor cell growth and the stemness and radiation response of glioma stem cells Correction