The Oncosearch | Oncotarget

Roscovitine enhances all-trans retinoic acid (ATRA)-induced nuclear enrichment of an ensemble of activated signaling molecules and augments ATRA-induced myeloid cell differentiation Research Paper

Asif Rashid, Xin Duan, Feng Gao, Mengsu Yang, Andrew Yen

Published Mar 24, 2020 · Vol. 11, No. 12 · pp. 1017-1036

Keywords: ATRA, roscovitine, APL, HL-60, Lyn

Characterization of iPS87, a prostate cancer stem cell-like cell line Research Paper

Erika N. Assoun, April N. Meyer, Maggie Y. Jiang, Stephen M. Baird, Martin Haas, Daniel J. Donoghue

Published Mar 24, 2020 · Vol. 11, No. 12 · pp. 1075-1084

Keywords: prostate cancer, stem cells, androgen independent, androgen deprivation therapy, castration resistant prostate cancer

Cancer associated fibroblasts confer shear resistance to circulating tumor cells during prostate cancer metastatic progression Research Paper

Nerymar Ortiz-Otero, Andrea B. Clinch, Jacob Hope, Wenjun Wang, Cynthia A. Reinhart-King, Michael R. King

Published Mar 24, 2020 · Vol. 11, No. 12 · pp. 1037-1050

Keywords: metastasis, cancer associated fibroblasts, circulating tumor cells, cytoprotection, collective migration

hPCL3S promotes proliferation and migration of androgen-independent prostate cancer cells Research Paper

Souhila Abdelfettah, Gaylor Boulay, Marion Dubuissez, Nathalie Spruyt, Sara P. Garcia, Shruthi Rengarajan, Ingrid Loison, Xavier Leroy, Miguel N. Rivera, Dominique Leprince

Published Mar 24, 2020 · Vol. 11, No. 12 · pp. 1051-1074

Keywords: hPCL3S, PHF19, PRC2, β-catenin, prostate cancer

Correction: Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes Correction

Faruck L. Hakkim, Hamid A. Bakshi, Shabia Khan, Mohamed M. Nasef, Rabia Farzand, Smitha Sam, Luay Rashan, Mohammed S. Al-Baloshi, Sidgi Syed Anwar Abdo Hasson, Ali Al Jabri, Paul A. McCarron, Murtaza M. Tambuwala

Published Mar 23, 2020 · Vol. 11, No. 23 · pp. 2259-2261

Combined inhibition of PIM and CDK4/6 suppresses both mTOR signaling and Rb phosphorylation and potentiates PI3K inhibition in cancer cells Priority Research Paper

Lacey M. Litchfield, Karsten Boehnke, Manisha Brahmachary, Cecilia Mur, Chen Bi, Jennifer R. Stephens, J. Michael Sauder, Sonia M. Gutiérrez, Ann M. McNulty, Xiang S. Ye, Wenjuan Wu, María José Lallena, Xueqian Gong, Farhana F. Merzoug, Valerie M. Jansen, Sean G. Buchanan

Published Mar 23, 2020 · Vol. 11, No. 17 · pp. 1478-1492

Keywords: abemaciclib, CDK4/6, PIM, mTOR, S6

Retraction: Non-epigenetic function of HDAC8 in regulating breast cancer stem cells by maintaining Notch1 protein stability Retraction

Min-Wu Chao, Po-Chen Chu, Hsiao-Ching Chuang, Fang-Hsiu Shen, Chih-Chien Chou, En-Chi Hsu, Lauren E. Himmel, Han-Li Huang, Huang-Ju Tu, Samuel K. Kulp, Che-Ming Teng, Ching-Shih Chen

Published Mar 19, 2020 · Vol. 11, No. 12 · pp. 1096-1096

Early prediction of resistance to tyrosine kinase inhibitors by plasma monitoring of EGFR mutations in NSCLC: a new algorithm for patient selection and personalized treatment Research Paper

Fiamma Buttitta, Lara Felicioni, Alessia Di Lorito, Alessio Cortellini, Luciana Irtelli, Davide Brocco, Pietro Di Marino, Donatella Traisci, Nicola D’Ostilio, Alessandra Di Paolo, Francesco Malorgio, Pasquale Assalone, Sonia Di Felice, Francesca Fabbri, Giovanni Cianci, Michele De Tursi, Antonio Marchetti

Published Mar 17, 2020 · Vol. 11, No. 11 · pp. 982-991

Keywords: epidermal growth factor receptor (EGFR), tyrosine-kinase Inhibitors, circulating tumor-DNA (ct-DNA), massive parallel sequencing (MPS), resistance-inducing mutation

Targeting PI3Kβ alone and in combination with chemotherapy or immunotherapy in tumors with PTEN loss Research Paper

Nicci Owusu-Brackett, Ming Zhao, Argun Akcakanat, Kurt W. Evans, Erkan Yuca, Ecaterina Ileana Dumbrava, Filip Janku, Funda Meric-Bernstam

Published Mar 17, 2020 · Vol. 11, No. 11 · pp. 969-981

Keywords: PI3Kβ, PTEN loss, AZD8186, chemotherapy, immunotherapy

A microRNA-based signature predicts local-regional failure and overall survival after pancreatic cancer resection Research Paper

Adam R. Wolfe, Patrick Wald, Amy Webb, Nikhil Sebastian, Steve Walston, Ryan Robb, Wei Chen, Marall Vedaie, Mary Dillhoff, Wendy L. Frankel, Wooil Kwon, Jin-Young Jang, Terence M. Williams

Published Mar 10, 2020 · Vol. 11, No. 10 · pp. 913-923

Keywords: pancreatic cancer, miRNA, non-coding RNA, prognostic biomarker, local-regional recurrence

Inducible knock-out of BCL6 in lymphoma cells results in tumor stasis Research Paper

Stefanie Schlager, Carina Salomon, Sabine Olt, Christoph Albrecht, Anja Ebert, Oliver Bergner, Johannes Wachter, Francesca Trapani, Daniel Gerlach, Tilman Voss, Anna Traunbauer, Julian Jude, Matthias Hinterndorfer, Martina Minnich, Norbert Schweifer, Sophia M. Blake, Vittoria Zinzalla, Barbara Drobits, Darryl B. McConnell, Norbert Kraut, Mark Pearson, Johannes Zuber, Manfred Koegl

Published Mar 3, 2020 · Vol. 11, No. 9 · pp. 875-890

Keywords: BCL6, DLBCL, lymphoma, inducible CRISPR/Cas9, in vivo xenograft

Calcitonin receptor is required for T-antigen-induced prostate carcinogenesis Research Paper

Ajay Kale, Afaf Aldahish, Girish Shah

Published Mar 3, 2020 · Vol. 11, No. 9 · pp. 858-874

Keywords: calcitonin receptor, T-antigen, tumor growth, PTEN, prostate cancer

Glypican-1 in human glioblastoma: implications in tumorigenesis and chemotherapy Research Paper

Eduardo Listik, Leny Toma

Published Mar 3, 2020 · Vol. 11, No. 9 · pp. 828-845

Keywords: glioblastoma, glypican-1, tumorigenesis, chemotherapy resistance, temozolomide

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

Cristina Kinahan, Michael A. Mangone, Luigi Scotto, Michele Visentin, Enrica Marchi, Hearn Jay Cho, Owen A. O’Connor

Published Feb 26, 2020 · Vol. 11, No. 18 · pp. 1576-1589

Keywords: antifolate, multiple myeloma, pralatrexate, biomarker, reduced folate carrier (RFC)

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

Cristina Kinahan, Michael A. Mangone, Luigi Scotto, Michele Visentin, Enrica Marchi, Hearn Jay Cho, Owen A. O’Connor

Published Feb 26, 2020

Keywords: antifolate, multiple myeloma, pralatrexate, biomarker, reduced folate carrier (RFC)

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

Cristina Kinahan, Michael A. Mangone, Luigi Scotto, Michele Visentin, Enrica Marchi, Hearn Jay Cho, Owen A. O’Connor

Published Feb 26, 2020

Keywords: antifolate, multiple myeloma, pralatrexate, biomarker, reduced folate carrier (RFC)

Both BRCA1-wild type and -mutant triple-negative breast cancers show sensitivity to the NAE inhibitor MLN4924 which is enhanced upon MLN4924 and cisplatin combination treatment Research Paper

Shrilekha Misra, Xiaoli Zhang, Nissar Ahmad Wani, Steven Sizemore, Alo Ray

Published Feb 25, 2020 · Vol. 11, No. 8 · pp. 784-800

Keywords: triple-negative breast cancer, MLN4924, cisplatin, cell cycle, DNA damage

SLC25A32 sustains cancer cell proliferation by regulating flavin adenine nucleotide (FAD) metabolism Research Paper

Valeria Santoro, Ilya Kovalenko, Kim Vriens, Stefan Christen, Andreas Bernthaler, Andrea Haegebarth, Sarah-Maria Fendt, Sven Christian

Published Feb 25, 2020 · Vol. 11, No. 8 · pp. 801-812

Keywords: transporter, mitochondria, metabolism, ROS, FAD

Randomized, double-blind trial of F14512, a polyamine-vectorized anticancer drug, compared with etoposide phosphate, in dogs with naturally occurring lymphoma Research Paper

Pierre Boyé, Franck Floch, François Serres, Zacharie Segaoula, Juliette Hordeaux, Quentin Pascal, Virginie Coste, Sandy Courapied, Emmanuel Bouchaert, Agata Rybicka, Claire Mazuy, Laurent Marescaux, Kévyn Geeraert, Corinne Fournel-Fleury, Alain Duhamel, François Machuron, Pierre Ferré, Aurélie Pétain, Nicolas Guilbaud, Dominique Tierny, Bruno Gomes

Published Feb 18, 2020 · Vol. 11, No. 7 · pp. 671-686

Keywords: etoposide phosphate, F14512, non-Hodgkin lymphoma, pet dog model, P-glycoprotein

MAGE-A inhibit apoptosis and promote proliferation in multiple myeloma through regulation of BIM and p21^Cip1 Research Paper

Anna Huo-Chang Mei, Kaity Tung, Jessie Han, Deepak Perumal, Alessandro Laganà, Jonathan Keats, Daniel Auclair, Ajai Chari, Sundar Jagannath, Samir Parekh, Hearn Jay Cho

Published Feb 18, 2020 · Vol. 11, No. 7 · pp. 727-739

Keywords: MAGE-A3, multiple myeloma, apoptosis, cell cycle regulation, DNA repair

Publication Alerts

European Cancer and Oncology Congress

Post-Publication Promotion

Search Oncotarget

Roscovitine enhances all-trans retinoic acid (ATRA)-induced nuclear enrichment of an ensemble of activated signaling molecules and augments ATRA-induced myeloid cell differentiation Research Paper

Characterization of iPS87, a prostate cancer stem cell-like cell line Research Paper

Cancer associated fibroblasts confer shear resistance to circulating tumor cells during prostate cancer metastatic progression Research Paper

hPCL3S promotes proliferation and migration of androgen-independent prostate cancer cells Research Paper

Correction: Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes Correction

Combined inhibition of PIM and CDK4/6 suppresses both mTOR signaling and Rb phosphorylation and potentiates PI3K inhibition in cancer cells Priority Research Paper

Retraction: Non-epigenetic function of HDAC8 in regulating breast cancer stem cells by maintaining Notch1 protein stability Retraction

Early prediction of resistance to tyrosine kinase inhibitors by plasma monitoring of EGFR mutations in NSCLC: a new algorithm for patient selection and personalized treatment Research Paper

Targeting PI3Kβ alone and in combination with chemotherapy or immunotherapy in tumors with PTEN loss Research Paper

A microRNA-based signature predicts local-regional failure and overall survival after pancreatic cancer resection Research Paper

Inducible knock-out of BCL6 in lymphoma cells results in tumor stasis Research Paper

Calcitonin receptor is required for T-antigen-induced prostate carcinogenesis Research Paper

Glypican-1 in human glioblastoma: implications in tumorigenesis and chemotherapy Research Paper

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

Both BRCA1-wild type and -mutant triple-negative breast cancers show sensitivity to the NAE inhibitor MLN4924 which is enhanced upon MLN4924 and cisplatin combination treatment Research Paper

SLC25A32 sustains cancer cell proliferation by regulating flavin adenine nucleotide (FAD) metabolism Research Paper

Randomized, double-blind trial of F14512, a polyamine-vectorized anticancer drug, compared with etoposide phosphate, in dogs with naturally occurring lymphoma Research Paper

MAGE-A inhibit apoptosis and promote proliferation in multiple myeloma through regulation of BIM and p21^Cip1 Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Roscovitine enhances all-trans retinoic acid (ATRA)-induced nuclear enrichment of an ensemble of activated signaling molecules and augments ATRA-induced myeloid cell differentiation Research Paper

Characterization of iPS87, a prostate cancer stem cell-like cell line Research Paper

Cancer associated fibroblasts confer shear resistance to circulating tumor cells during prostate cancer metastatic progression Research Paper

hPCL3S promotes proliferation and migration of androgen-independent prostate cancer cells Research Paper

Correction: Frankincense essential oil suppresses melanoma cancer through down regulation of Bcl-2/Bax cascade signaling and ameliorates heptotoxicity via phase I and II drug metabolizing enzymes Correction

Combined inhibition of PIM and CDK4/6 suppresses both mTOR signaling and Rb phosphorylation and potentiates PI3K inhibition in cancer cells Priority Research Paper

Retraction: Non-epigenetic function of HDAC8 in regulating breast cancer stem cells by maintaining Notch1 protein stability Retraction

Early prediction of resistance to tyrosine kinase inhibitors by plasma monitoring of EGFR mutations in NSCLC: a new algorithm for patient selection and personalized treatment Research Paper

Targeting PI3Kβ alone and in combination with chemotherapy or immunotherapy in tumors with PTEN loss Research Paper

A microRNA-based signature predicts local-regional failure and overall survival after pancreatic cancer resection Research Paper

Inducible knock-out of BCL6 in lymphoma cells results in tumor stasis Research Paper

Calcitonin receptor is required for T-antigen-induced prostate carcinogenesis Research Paper

Glypican-1 in human glioblastoma: implications in tumorigenesis and chemotherapy Research Paper

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

The anti-tumor activity of pralatrexate (PDX) correlates with the expression of RFC and DHFR mRNA in preclinical models of multiple myeloma Research Paper

Both BRCA1-wild type and -mutant triple-negative breast cancers show sensitivity to the NAE inhibitor MLN4924 which is enhanced upon MLN4924 and cisplatin combination treatment Research Paper

SLC25A32 sustains cancer cell proliferation by regulating flavin adenine nucleotide (FAD) metabolism Research Paper

Randomized, double-blind trial of F14512, a polyamine-vectorized anticancer drug, compared with etoposide phosphate, in dogs with naturally occurring lymphoma Research Paper

MAGE-A inhibit apoptosis and promote proliferation in multiple myeloma through regulation of BIM and p21Cip1 Research Paper

MAGE-A inhibit apoptosis and promote proliferation in multiple myeloma through regulation of BIM and p21^Cip1 Research Paper