The Oncosearch | Oncotarget

Therapeutic inhibition of Mcl-1 blocks cell survival in estrogen receptor-positive breast cancers Research Paper

Michelle M. Williams, David L. Elion, Bushra Rahman, Donna J. Hicks, Violeta Sanchez, Rebecca S. Cook

Published Sep 10, 2019 · Vol. 10, No. 52 · pp. 5389-5402

Keywords: Mcl-1, ABT-263 resistance, mTORC1 signaling, luminal breast cancers

Safety evaluation of conditionally immortalized cells for renal replacement therapy Research Paper

Milos Mihajlovic, Sam Hariri, Koen C.G. Westphal, Manoe J. Janssen, Miriam J. Oost, Laura Bongiovanni, Lambertus P. van den Heuvel, Alain de Bruin, Luuk B. Hilbrands, Rosalinde Masereeuw

Published Sep 3, 2019 · Vol. 10, No. 51 · pp. 5332-5348

Keywords: bioartificial kidney, cell therapy safety, conditionally immortalized proximal tubule epithelial cells, tumorigenicity, viral integration

Genome-wide miRNA profiling and pivotal roles of miRs 125a-5p and 17-92 cluster in human neutrophil maturation and differentiation of acute myeloid leukemia cells Research Paper

El-Habib Dakir, Faustino Mollinedo

Published Sep 3, 2019 · Vol. 10, No. 51 · pp. 5313-5331

Keywords: miRNA, miR-125a-5p, miR-17-92, neutrophil differentiation, human

Tumor penetrating nanomedicine targeting both an oncomiR and an oncogene in pancreatic cancer Research Paper

Maud-Emmanuelle Gilles, Liangliang Hao, Kaelyn Brown, Jihoon Lim, Sangeeta N. Bhatia, Frank J. Slack

Published Sep 3, 2019 · Vol. 10, No. 51 · pp. 5349-5358

Keywords: miRNAs, KRAS, RNA-based-therapy, PDAC, tumor-penetrating nanocomplexes

DS-1205b, a novel selective inhibitor of AXL kinase, blocks resistance to EGFR-tyrosine kinase inhibitors in a non-small cell lung cancer xenograft model Research Paper

Takeshi Jimbo, Mana Hatanaka, Takahiro Komatsu, Tomoe Taira, Kentaro Kumazawa, Naoyuki Maeda, Takashi Suzuki, Masahiro Ota, Noriyasu Haginoya, Takeshi Isoyama, Kosaku Fujiwara

Published Aug 27, 2019 · Vol. 10, No. 50 · pp. 5152-5167

Keywords: AXL, DS-1205, EGFR-TKI resistance, erlotinib, osimertinib

Ras functional proximity proteomics establishes mTORC2 as new direct ras effector Research Perspective

Joanna R. Kovalski, Ronald L. Shanderson, Paul A. Khavari

Published Aug 27, 2019 · Vol. 10, No. 50 · pp. 5126-5135

Keywords: Ras, BioID, proteomics, CRISPR, mTORC2

Inefficient induction of circulating TAA-specific CD8+ T-cell responses in hepatocellular carcinoma Research Paper

Catrin Tauber, Michael Schultheiss, Raffaele De Luca, Nico Buettner, Sian Llewellyn-Lacey, Florian Emmerich, Sebastian Zehe, David A. Price, Christoph Neumann-Haefelin, Annette Schmitt-Graeff, Maike Hofmann, Robert Thimme

Published Aug 27, 2019 · Vol. 10, No. 50 · pp. 5194-5206

Keywords: TAA, MAGE-A, HCC, T-cell exhaustion, liver cirrhosis

Repurposed quinacrine synergizes with cisplatin, reducing the effective dose required for treatment of head and neck squamous cell carcinoma Research Paper

Jennifer Bryant, Nikolaos Batis, Anna Clara Franke, Gabriella Clancey, Margaret Hartley, Gordon Ryan, Jill Brooks, Andrew D. Southam, Nicholas Barnes, Joanna Parish, Sally Roberts, Farhat Khanim, Rachel Spruce, Hisham Mehanna

Published Aug 27, 2019 · Vol. 10, No. 50 · pp. 5229-5244

Keywords: head and neck cancer, drug repurposing, drug repositioning, quinacrine, mepacrine

Correction: Synergistic interactions between PLK1 and HDAC inhibitors in non-Hodgkin’s lymphoma cells occur in vitro and in vivo and proceed through multiple mechanisms Correction

Tri Nguyen, Rebecca Parker, Elisa Hawkins, Beata Holkova, Victor Yazbeck, Akhil Kolluri, Maciej Kmieciak, Mohamed Rahmani, Steven Grant

Published Aug 26, 2019 · Vol. 10, No. 51 · pp. 5383-5384

Correction: Upregulation of long non-coding RNA PlncRNA-1 promotes proliferation and induces epithelial-mesenchymal transition in prostate cancer Correction

Yang Jin, Zilian Cui, Xudong Li, Xunbo Jin, Jian Peng

Published Aug 24, 2019 · Vol. 10, No. 50 · pp. 5253-5253

Identification of α-N-catenin as a novel tumor suppressor in neuroblastoma Research Paper

Jingbo Qiao, Eric J. Rellinger, Kwang Woon Kim, Camille M. Powers, Sora Lee, Hernan Correa, Dai H. Chung

Published Aug 20, 2019 · Vol. 10, No. 49 · pp. 5028-5040

Keywords: neuroblastoma, tumor suppressor, CTNNA2 (α-N-catenin), NF-κB

Vascular endothelium function among male carriers of BRCA 1&2 germline mutation Research Paper

Guy Witberg, Eli Lev, Yaara Ber, Tzlil Tabachnik, Sivan Sela, Ira Belo, Dorit Leshem-Lev, David Margel

Published Aug 20, 2019 · Vol. 10, No. 49 · pp. 5041-5051

Keywords: BRCA, DNA repair, endothelial progenitor cells, vascular endothelium damage, cardiovascular system

Idiotypic and anti-idiotypic antibodies against polycyclic aromatic hydrocarbon in human blood serum are new biomarkers of lung cancer Research Paper

Ivan S. Grebenshchikov, Artem E. Studennikov, Vadim I. Ivanov, Natalia V. Ivanova, Victor A. Titov, Natalja E. Vergbickaya, Valentin A. Ustinov

Published Aug 20, 2019 · Vol. 10, No. 49 · pp. 5070-5081

Keywords: polycyclic aromatic hydrocarbon, benzo[a]pyrene, anti-idiotypic antibodies, idiotypic antibodies, lung cancer

PTEN interacts with RNA polymerase II to dephosphorylate polymerase II C-terminal domain Research Paper

Ata Abbas, Todd Romigh, Charis Eng

Published Aug 13, 2019 · Vol. 10, No. 48 · pp. 4951-4959

Keywords: phosphatase and tensin homolog (PTEN), cowden syndrome, PTEN hamartoma tumor syndrome, RNA polymerase II, Pol II CTD dephosphorylation

Association of baseline inflammatory biomarkers with cancer mortality in the REGARDS cohort Research Paper

Tomi Akinyemiju, Justin X. Moore, Daniel Tefera Dibaba, Maria Pisu, Michael Goodman, Virginia J. Howard, Monika Safford, Susan C. Gilchrist, Mary Cushman, LeAnn Long, Suzanne E. Judd

Published Aug 6, 2019 · Vol. 10, No. 47 · pp. 4857-4867

Keywords: inflammatory biomarkers, racial disparities, cancer mortality, obesity

Combinatorial drug screening of mammary cells with induced mesenchymal transformation to identify drug combinations for triple-negative breast cancer Research Paper

Sierra A. Colavito, James T. Platt, Matthew A. Held, Zongzhi Liu, Ryan Sokup, David F. Stern

Published Aug 6, 2019 · Vol. 10, No. 47 · pp. 4822-4839

Keywords: epithelial-mesenchymal transition, triple-negative breast cancer, targeted drug combination screen, claudin-low breast cancer, CHK1

KDM2A-dependent reduction of rRNA transcription on glucose starvation requires HP1 in cells, including triple-negative breast cancer cells Research Paper

Kengo Okamoto, Yuji Tanaka, Sachiko Ogasawara, Chikashi Obuse, Jun-ichi Nakayama, Hirohisa Yano, Makoto Tsuneoka

Published Jul 30, 2019 · Vol. 10, No. 46 · pp. 4743-4760

Keywords: HP1, KDM2A, nucleoli, rRNA, TNBC

Impact on survival of tobacco smoking for cases with oropharyngeal squamous cell carcinoma and known human papillomavirus and p16-status: a multicenter retrospective study Research Paper

Christian Grønhøj, Jakob Schmidt Jensen, Steffen Wagner, Christian Dehlendorff, Jeppe Friborg, Elo Andersen, Claus Wittekindt, Nora Würdemann, Shachi Jenny Sharma, Stefan Gattenlöhner, Jens Peter Klussmann, Christian von Buchwald

Published Jul 23, 2019 · Vol. 10, No. 45 · pp. 4655-4663

Keywords: oropharyngeal cancer, human papillomavirus, smoking, survival

CpG promoter hypo-methylation and up-regulation of microRNA-190b in hormone receptor-positive breast cancer Research Paper

Elisabet Frick, Thorkell Gudjonsson, Jorunn Eyfjord, Jon Jonasson, Laufey Tryggvadóttir, Olafur Stefansson, Stefan Sigurdsson

Published Jul 23, 2019 · Vol. 10, No. 45 · pp. 4664-4678

Keywords: breast cancer, microRNA-190b, DNA methylation, prognosis, estrogen receptor

Fibroblast-derived Gremlin1 localises to epithelial cells at the base of the intestinal crypt Research Paper

Louise R. Dutton, Owen P. Hoare, Amy M.B. McCorry, Keara L. Redmond, Noor Eisa Adam, Shannon Canamara, Victoria Bingham, Paul B. Mullan, Mark Lawler, Philip D. Dunne, Derek P. Brazil

Published Jul 23, 2019 · Vol. 10, No. 45 · pp. 4630-4639

Keywords: Gremlin1, colorectal cancer, fibroblasts, stroma, pathology

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Therapeutic inhibition of Mcl-1 blocks cell survival in estrogen receptor-positive breast cancers Research Paper

Safety evaluation of conditionally immortalized cells for renal replacement therapy Research Paper

Genome-wide miRNA profiling and pivotal roles of miRs 125a-5p and 17-92 cluster in human neutrophil maturation and differentiation of acute myeloid leukemia cells Research Paper

Tumor penetrating nanomedicine targeting both an oncomiR and an oncogene in pancreatic cancer Research Paper

DS-1205b, a novel selective inhibitor of AXL kinase, blocks resistance to EGFR-tyrosine kinase inhibitors in a non-small cell lung cancer xenograft model Research Paper

Ras functional proximity proteomics establishes mTORC2 as new direct ras effector Research Perspective

Inefficient induction of circulating TAA-specific CD8+ T-cell responses in hepatocellular carcinoma Research Paper

Repurposed quinacrine synergizes with cisplatin, reducing the effective dose required for treatment of head and neck squamous cell carcinoma Research Paper

Correction: Synergistic interactions between PLK1 and HDAC inhibitors in non-Hodgkin’s lymphoma cells occur in vitro and in vivo and proceed through multiple mechanisms Correction

Correction: Upregulation of long non-coding RNA PlncRNA-1 promotes proliferation and induces epithelial-mesenchymal transition in prostate cancer Correction

Identification of α-N-catenin as a novel tumor suppressor in neuroblastoma Research Paper

Vascular endothelium function among male carriers of BRCA 1&2 germline mutation Research Paper

Idiotypic and anti-idiotypic antibodies against polycyclic aromatic hydrocarbon in human blood serum are new biomarkers of lung cancer Research Paper

PTEN interacts with RNA polymerase II to dephosphorylate polymerase II C-terminal domain Research Paper

Association of baseline inflammatory biomarkers with cancer mortality in the REGARDS cohort Research Paper

Combinatorial drug screening of mammary cells with induced mesenchymal transformation to identify drug combinations for triple-negative breast cancer Research Paper

KDM2A-dependent reduction of rRNA transcription on glucose starvation requires HP1 in cells, including triple-negative breast cancer cells Research Paper

Impact on survival of tobacco smoking for cases with oropharyngeal squamous cell carcinoma and known human papillomavirus and p16-status: a multicenter retrospective study Research Paper

CpG promoter hypo-methylation and up-regulation of microRNA-190b in hormone receptor-positive breast cancer Research Paper

Fibroblast-derived Gremlin1 localises to epithelial cells at the base of the intestinal crypt Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Therapeutic inhibition of Mcl-1 blocks cell survival in estrogen receptor-positive breast cancers Research Paper

Safety evaluation of conditionally immortalized cells for renal replacement therapy Research Paper

Genome-wide miRNA profiling and pivotal roles of miRs 125a-5p and 17-92 cluster in human neutrophil maturation and differentiation of acute myeloid leukemia cells Research Paper

Tumor penetrating nanomedicine targeting both an oncomiR and an oncogene in pancreatic cancer Research Paper

DS-1205b, a novel selective inhibitor of AXL kinase, blocks resistance to EGFR-tyrosine kinase inhibitors in a non-small cell lung cancer xenograft model Research Paper

Ras functional proximity proteomics establishes mTORC2 as new direct ras effector Research Perspective

Inefficient induction of circulating TAA-specific CD8+ T-cell responses in hepatocellular carcinoma Research Paper

Repurposed quinacrine synergizes with cisplatin, reducing the effective dose required for treatment of head and neck squamous cell carcinoma Research Paper

Correction: Synergistic interactions between PLK1 and HDAC inhibitors in non-Hodgkin’s lymphoma cells occur in vitro and in vivo and proceed through multiple mechanisms Correction

Correction: Upregulation of long non-coding RNA PlncRNA-1 promotes proliferation and induces epithelial-mesenchymal transition in prostate cancer Correction

Identification of α-N-catenin as a novel tumor suppressor in neuroblastoma Research Paper

Vascular endothelium function among male carriers of BRCA 1&2 germline mutation Research Paper

Idiotypic and anti-idiotypic antibodies against polycyclic aromatic hydrocarbon in human blood serum are new biomarkers of lung cancer Research Paper

PTEN interacts with RNA polymerase II to dephosphorylate polymerase II C-terminal domain Research Paper

Association of baseline inflammatory biomarkers with cancer mortality in the REGARDS cohort Research Paper

Combinatorial drug screening of mammary cells with induced mesenchymal transformation to identify drug combinations for triple-negative breast cancer Research Paper

KDM2A-dependent reduction of rRNA transcription on glucose starvation requires HP1 in cells, including triple-negative breast cancer cells Research Paper

Impact on survival of tobacco smoking for cases with oropharyngeal squamous cell carcinoma and known human papillomavirus and p16-status: a multicenter retrospective study Research Paper

CpG promoter hypo-methylation and up-regulation of microRNA-190b in hormone receptor-positive breast cancer Research Paper

Fibroblast-derived Gremlin1 localises to epithelial cells at the base of the intestinal crypt Research Paper