The Oncosearch | Oncotarget

Graded expression of microRNA-371a-3p in tumor tissues, contralateral testes, and in serum of patients with testicular germ cell tumor Research Paper

Gazanfer Belge, Finja Hennig, Cansu Dumlupinar, Francesca Grobelny, Klaus Junker, Arlo Radtke, Klaus-Peter Dieckmann

Published Apr 21, 2020 · Vol. 11, No. 16 · pp. 1462-1473

Keywords: testicular germ cell tumors, microRNA-371a-3p, serum, contralateral testes, in situ hybridization

Fatty changes associated with N-Nitrosodiethylamine (DEN) induced hepatocellular carcinoma: a role of sonic hedgehog signaling pathway Research Paper

Anindita Tripathy, Sudhir Thakurela, Manoj Kumar Sahu, Kanishka Uthansingh, Ayaskanta Singh, Jimmy Narayan, Amrendra Kumar Ajay, Vinay Singh, Ratna Kumari

Published Apr 20, 2020

Keywords: hepatocellular carcinoma, adiposity, SHH-E2F1 pathway, lipogenic molecules, adiponectin

Expression of receptor activator of NFkB (RANK) drives stemness and resistance to therapy in ER+HER2- breast cancer Research Paper

Inês Gomes, Bernardo P. de Almeida, Sara Dâmaso, André Mansinho, Inês Correia, Sara Henriques, Raquel Cruz-Duarte, Guilherme Vilhais, Pedro Félix, Patrícia Alves, Patrícia Corredeira, Nuno L. Barbosa-Morais, Luis Costa, Sandra Casimiro

Published Apr 18, 2020 · Vol. 11, No. 19 · pp. 1714-1728

Keywords: RANKL-RANK pathway, ER+ breast cancer, resistance to chemo and hormone therapy, stemness, metastization

Distinct pattern of one-carbon metabolism, a nutrient-sensitive pathway, in invasive breast cancer: A metabolomic study Research Paper

Jéssica Reis Santos, Dan Linetzky Waitzberg, Ismael Dale Cotrim Guerreiro da Silva, Tharcisio Citrangulo Tortelli Junior, Luciana Rodrigues Carvalho Barros, Gisele André Baptista Canuto, Andréa Tedesco Faccio, Lydia Fumiko Yamaguchi, Massuo Jorge Kato, Marina Franco Maggi Tavares, Ana Cristina Martinez, Ângela Flavia Logullo, Raquel Suzana M.M. Torrinhas, Graziela Ravacci

Published Apr 18, 2020 · Vol. 11, No. 18 · pp. 1637-1652

Keywords: invasive ductal carcinoma, targeted metabolomics, untargeted metabolomics, tumor metabolism, one-carbon metabolism

Knock-down of the TIM/TIPIN complex promotes apoptosis in melanoma cells Research Paper

Abhijit Chakraborty, Faisal Aziz, Eunmiri Roh, Le Thi My Le, Raja Dey, Tianshun Zhang, Moeez G. Rathore, Aalekhya Sharma Biswas, Ann M. Bode, Zigang Dong

Published Apr 17, 2020 · Vol. 11, No. 20 · pp. 1846-1861

Keywords: TIMELESS, TIPIN, apoptosis, xenograft, Cryo-EM

Protein phosphatase 1 regulatory subunit 1A regulates cell cycle progression in Ewing sarcoma Research Paper

Wen Luo, Changxin Xu, Sarah Phillips, Aliza Gardenswartz, Jeremy M. Rosenblum, Janet Ayello, Stephen L. Lessnick, Huai-Xiang Hao, Mitchell S. Cairo

Published Apr 16, 2020 · Vol. 11, No. 19 · pp. 1691-1704

Keywords: PPP1R1A, cell cycle control, IGF-1R, metastasis, Ewing sarcoma

CD44+/EPCAM+ cells detect a subpopulation of ALDH^high cells in human non-small cell lung cancer: A chance for targeting cancer stem cells? Research Paper

Valentina Masciale, Giulia Grisendi, Federico Banchelli, Roberto D’Amico, Antonino Maiorana, Pamela Sighinolfi, Alessandro Stefani, Uliano Morandi, Massimo Dominici, Beatrice Aramini

Published Apr 16, 2020 · Vol. 11, No. 17 · pp. 1545-1555

Keywords: immunophenotype, cancer stem cells, cancer stem-like cells, non-small cell lung cancer (NSCLC), target therapy

Pirfenidone anti-fibrotic effects are partially mediated by the inhibition of MUC1 bioactivation Research Paper

Beatriz Ballester, Javier Milara, Julio Cortijo

Published Apr 14, 2020 · Vol. 11, No. 15 · pp. 1306-1320

Keywords: pirfenidone, idiopathic pulmonary fibrosis, MUC1, transforming growth factor beta-1, fibroblasts

Association of germline genetic variants with TMPRSS2-ERG fusion status in prostate cancer Research Paper

Indu Kohaar, Qiyuan Li, Yongmei Chen, Lakshmi Ravindranath, Denise Young, Amina Ali, Isabell A. Sesterhenn, Inger L. Rosner, Jennifer Cullen, Shiv Srivastava, Matthew Freedman, Gyorgy Petrovics

Published Apr 14, 2020 · Vol. 11, No. 15 · pp. 1321-1333

Keywords: prostate cancer, TMPRSS2-ERG, molecular subtype, ERG fusion, SNP

Molecular imaging reveals biodistribution of P-cadherin LP-DART bispecific and trafficking of adoptively transferred T cells in mouse xenograft model Research Paper

Vijay R. Gupta, Adam Root, Timothy Fisher, Rand Norberg, John David, Tracey Clark, Justin Cohen, Chad May, Anand Giddabasappa

Published Apr 14, 2020 · Vol. 11, No. 15 · pp. 1344-1357

Keywords: bispecific antibody, tumor targeting, biodistribution, T cells, molecular imaging

Does breast carcinoma belong to the Lynch syndrome tumor spectrum? – Somatic mutational profiles vs. ovarian and colorectal carcinomas Research Paper

Noora K. Porkka, Alisa Olkinuora, Teijo Kuopio, Maarit Ahtiainen, Samuli Eldfors, Henrikki Almusa, Jukka-Pekka Mecklin, Päivi Peltomäki

Published Apr 7, 2020 · Vol. 11, No. 14 · pp. 1244-1256

Keywords: Lynch syndrome, breast carcinoma, MSI, DNA mismatch repair, somatic mutation

Inhibition of SYK kinase does not confer a pro-proliferative or pro-invasive phenotype in breast epithelium or breast cancer cells Research Paper

David J. Lamb, Aleksander Rust, Albin Rudisch, Tobias Glüxam, Nathalie Harrer, Herwig Machat, Ingrid Christ, Florian Colbatzky, Andreas Wernitznig, Annika Osswald, Wolfgang Sommergruber

Published Apr 7, 2020 · Vol. 11, No. 14 · pp. 1257-1272

Keywords: SYK inhibitor, breast carcinoma, 3D culture, murine mammary gland, proliferation

First-in-human study of anticancer immunotherapy drug candidate mobilan: safety, pharmacokinetics and pharmacodynamics in prostate cancer patients Research Paper

Natalia V. Eremina, Vasily I. Kazey, Sergey V. Mishugin, Roman V. Leonenkov, Dmitry Y. Pushkar, Vadim L. Mett, Andrei V. Gudkov

Published Apr 7, 2020 · Vol. 11, No. 14 · pp. 1273-1288

Keywords: prostate cancer, immunotherapy, mobilan, adenoviral vector, intratumor injection

A mutation-specific, single-arm, phase 2 study of dovitinib in patients with advanced malignancies Research Paper

Matthew H. Taylor, Ajjai S. Alva, Timothy Larson, Sebastian Szpakowski, Das Purkaystha, Alpesh Amin, Linda Karpiak, Sarina A. Piha-Paul

Published Apr 7, 2020 · Vol. 11, No. 14 · pp. 1235-1243

Keywords: advanced malignancies, basket trial, dovitinib, histology-agnostic, mutation-specific

Quinacrine inhibits GSTA1 activity and induces apoptosis through G₁/S arrest and generation of ROS in human non-small cell lung cancer cell lines Research Paper

Makhan Kumar, Ansie Martin, Snehal Nirgude, Bibha Chaudhary, Sukanta Mondal, Angshuman Sarkar

Published Apr 6, 2020 · Vol. 11, No. 18 · pp. 1603-1617

Keywords: quinacrine, NSCLC, RhoGTPases, apoptosis, cell cycle

The value of lncRNA FENDRR and FOXF1 as a prognostic factor for survival of lung adenocarcinoma Research Paper

Antonio Herrera-Merchan, Marta Cuadros, Maria Isabel Rodriguez, Sandra Rodriguez, Raul Torres, Marcos Estecio, Isabel F. Coira, Claudia Loidi, Monica Saiz, Pedro Carmona-Saez, Pedro P. Medina

Published Mar 31, 2020 · Vol. 11, No. 13 · pp. 1172-1185

Synergistic cytotoxic activity of cannabinoids from cannabis sativa against cutaneous T-cell lymphoma (CTCL) in-vitro and ex-vivo Research Paper

Moran Mazuz, Amir Tiroler, Lilach Moyal, Emmilia Hodak, Stalin Nadarajan, Ajjampura C. Vinayaka, Batia Gorovitz-Haris, Ido Lubin, Avi Drori, Guy Drori, Owen Van Cauwenberghe, Adi Faigenboim, Dvora Namdar, Iris Amitay-Laish, Hinanit Koltai

Published Mar 31, 2020 · Vol. 11, No. 13 · pp. 1141-1156

Keywords: cutaneous T-cell lymphoma, cannabis, cannabinoids, peripheral blood lymphocytes, CTCL cell lines

Exosome mediated miR-155 delivery confers cisplatin chemoresistance in oral cancer cells via epithelial-mesenchymal transition Research Paper

Prathibha Kirave, Piyush Gondaliya, Bhagyashri Kulkarni, Rakesh Rawal, Rachana Garg, Alok Jain, Kiran Kalia

Published Mar 31, 2020 · Vol. 11, No. 13 · pp. 1157-1171

Keywords: cisplatin chemoresistance, miRNA155, exosomes, oral cancer, apoptosis

Investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish Research Paper

Hyejeong Rosemary Kim, Kirankumar Santhakumar, Eleanor Markham, Davide Baldera, David Greenald, Helen E. Bryant, Sherif F. El-Khamisy, Fredericus J. van Eeden

Published Mar 31, 2020 · Vol. 11, No. 13 · pp. 1109-1130

Keywords: Hif, Vhl, DNA repair, apoptosis, chemo/radio-resistance

Pineal gland protects against chemically induced oral carcinogenesis and inhibits tumor progression in rats Research Paper

Giseli Mitsuy Kayahara, Vitor Bonetti Valente, Rosani Belzunces Pereira, Felipe Yudi Kabeya Lopes, Marcelo Macedo Crivelini, Glauco Issamu Miyahara, Éder Ricardo Biasoli, Sandra Helena Penha Oliveira, Daniel Galera Bernabé

Published Mar 28, 2020 · Vol. 11, No. 20 · pp. 1816-1831

Keywords: melatonin, cancer, oral cancer, carcinogenesis, pineal gland

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Graded expression of microRNA-371a-3p in tumor tissues, contralateral testes, and in serum of patients with testicular germ cell tumor Research Paper

Fatty changes associated with N-Nitrosodiethylamine (DEN) induced hepatocellular carcinoma: a role of sonic hedgehog signaling pathway Research Paper

Expression of receptor activator of NFkB (RANK) drives stemness and resistance to therapy in ER+HER2- breast cancer Research Paper

Distinct pattern of one-carbon metabolism, a nutrient-sensitive pathway, in invasive breast cancer: A metabolomic study Research Paper

Knock-down of the TIM/TIPIN complex promotes apoptosis in melanoma cells Research Paper

Protein phosphatase 1 regulatory subunit 1A regulates cell cycle progression in Ewing sarcoma Research Paper

CD44+/EPCAM+ cells detect a subpopulation of ALDH^high cells in human non-small cell lung cancer: A chance for targeting cancer stem cells? Research Paper

Pirfenidone anti-fibrotic effects are partially mediated by the inhibition of MUC1 bioactivation Research Paper

Association of germline genetic variants with TMPRSS2-ERG fusion status in prostate cancer Research Paper

Molecular imaging reveals biodistribution of P-cadherin LP-DART bispecific and trafficking of adoptively transferred T cells in mouse xenograft model Research Paper

Does breast carcinoma belong to the Lynch syndrome tumor spectrum? – Somatic mutational profiles vs. ovarian and colorectal carcinomas Research Paper

Inhibition of SYK kinase does not confer a pro-proliferative or pro-invasive phenotype in breast epithelium or breast cancer cells Research Paper

First-in-human study of anticancer immunotherapy drug candidate mobilan: safety, pharmacokinetics and pharmacodynamics in prostate cancer patients Research Paper

A mutation-specific, single-arm, phase 2 study of dovitinib in patients with advanced malignancies Research Paper

Quinacrine inhibits GSTA1 activity and induces apoptosis through G₁/S arrest and generation of ROS in human non-small cell lung cancer cell lines Research Paper

The value of lncRNA FENDRR and FOXF1 as a prognostic factor for survival of lung adenocarcinoma Research Paper

Synergistic cytotoxic activity of cannabinoids from cannabis sativa against cutaneous T-cell lymphoma (CTCL) in-vitro and ex-vivo Research Paper

Exosome mediated miR-155 delivery confers cisplatin chemoresistance in oral cancer cells via epithelial-mesenchymal transition Research Paper

Investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish Research Paper

Pineal gland protects against chemically induced oral carcinogenesis and inhibits tumor progression in rats Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Graded expression of microRNA-371a-3p in tumor tissues, contralateral testes, and in serum of patients with testicular germ cell tumor Research Paper

Fatty changes associated with N-Nitrosodiethylamine (DEN) induced hepatocellular carcinoma: a role of sonic hedgehog signaling pathway Research Paper

Expression of receptor activator of NFkB (RANK) drives stemness and resistance to therapy in ER+HER2- breast cancer Research Paper

Distinct pattern of one-carbon metabolism, a nutrient-sensitive pathway, in invasive breast cancer: A metabolomic study Research Paper

Knock-down of the TIM/TIPIN complex promotes apoptosis in melanoma cells Research Paper

Protein phosphatase 1 regulatory subunit 1A regulates cell cycle progression in Ewing sarcoma Research Paper

CD44+/EPCAM+ cells detect a subpopulation of ALDHhigh cells in human non-small cell lung cancer: A chance for targeting cancer stem cells? Research Paper

Pirfenidone anti-fibrotic effects are partially mediated by the inhibition of MUC1 bioactivation Research Paper

Association of germline genetic variants with TMPRSS2-ERG fusion status in prostate cancer Research Paper

Molecular imaging reveals biodistribution of P-cadherin LP-DART bispecific and trafficking of adoptively transferred T cells in mouse xenograft model Research Paper

Does breast carcinoma belong to the Lynch syndrome tumor spectrum? – Somatic mutational profiles vs. ovarian and colorectal carcinomas Research Paper

Inhibition of SYK kinase does not confer a pro-proliferative or pro-invasive phenotype in breast epithelium or breast cancer cells Research Paper

First-in-human study of anticancer immunotherapy drug candidate mobilan: safety, pharmacokinetics and pharmacodynamics in prostate cancer patients Research Paper

A mutation-specific, single-arm, phase 2 study of dovitinib in patients with advanced malignancies Research Paper

Quinacrine inhibits GSTA1 activity and induces apoptosis through G1/S arrest and generation of ROS in human non-small cell lung cancer cell lines Research Paper

The value of lncRNA FENDRR and FOXF1 as a prognostic factor for survival of lung adenocarcinoma Research Paper

Synergistic cytotoxic activity of cannabinoids from cannabis sativa against cutaneous T-cell lymphoma (CTCL) in-vitro and ex-vivo Research Paper

Exosome mediated miR-155 delivery confers cisplatin chemoresistance in oral cancer cells via epithelial-mesenchymal transition Research Paper

Investigation of the role of VHL-HIF signaling in DNA repair and apoptosis in zebrafish Research Paper

Pineal gland protects against chemically induced oral carcinogenesis and inhibits tumor progression in rats Research Paper

CD44+/EPCAM+ cells detect a subpopulation of ALDH^high cells in human non-small cell lung cancer: A chance for targeting cancer stem cells? Research Paper

Quinacrine inhibits GSTA1 activity and induces apoptosis through G₁/S arrest and generation of ROS in human non-small cell lung cancer cell lines Research Paper