The Oncosearch | Oncotarget

Alterations of immune response of non-small cell lung cancer with Azacytidine Research Paper

John Wrangle, Wei Wang, Alexander Koch, Hariharan Easwaran, Helai P. Mohammad, Xiaoyu Pan, Frank Vendetti, Wim VanCriekinge, Tim DeMeyer, Zhengzong Du, Princy Parsana, Kristen Rodgers, Ray-Whay Yen, Cynthia A. Zahnow, Janis M. Taube, Julie R. Brahmer, Scott S. Tykodi, Keith Easton, Richard D. Carvajal, Peter A. Jones, Peter W. Laird, Daniel J. Weisenberger, Salina Tsai, Rosalyn A. Juergens, Suzanne L. Topalian, Charles M. Rudin, Malcolm V. Brock, Drew Pardoll, Stephen B. Baylin

Published Oct 25, 2013 · Vol. 4, No. 11 · pp. 2067-2079

Reduction of MLH1 and PMS2 confers temozolomide resistance and is associated with recurrence of glioblastoma Research Paper

Yoshinari Shinsato, Tatsuhiko Furukawa, Shunji Yunoue, Hajime Yonezawa, Kentarou Minami, Yukihiko Nishizawa, Ryuji Ikeda, Kohichi Kawahara, Masatatsu Yamamoto, Hirofumi Hirano, Hiroshi Tokimura, Kazunori Arita

Published Oct 14, 2013 · Vol. 4, No. 12 · pp. 2261-2270

Keywords: temozolomide, MLH1, PMS2, MutL-alphaï€, resistance, recurrence, glioblastoma

NFkB disrupts tissue polarity in 3D by preventing integration of microenvironmental signals Research Paper

Sabine Becker-Weimann, Gaofeng Xiong, Saori Furuta, Ju Han, Irene Kuhn, Uri-David Akavia, Dana Pe'er, Mina J. Bissell, Ren Xu

Published Oct 14, 2013 · Vol. 4, No. 11 · pp. 2010-2020

Keywords: disorganization gene signature, p65, RelB, three-dimensional tissue structure, tissue polarity

Lysine-specific modifications of p53: a matter of life and death? Review

Diana Marouco, Alexander V Garabadgiu, Gerry Melino, Nick A Barlev

Published Oct 8, 2013 · Vol. 4, No. 10 · pp. 1556-1571

Keywords: p53, post-translational modifications, lysine methylation, acetylation

Chemoresistance to gemcitabine in hepatoma cells induces epithelial-mesenchymal transition and involves activation of PDGF-D pathway Research Paper

Qiong Wu, Rui Wang, Qingling Yang, Xin Hou, Sulian Chen, Yueyue Hou, Changjie Chen, Yan Yang, Lucio Miele, Fazlul Sarkar, Yuqing Chen, Zhiwei Wang

Published Oct 7, 2013 · Vol. 4, No. 11 · pp. 1999-2009

Keywords: Hepatocellular carcinoma, chemoresistance, PDGF-D, EMT, gemcitabine

PTRF/Cavin-1 decreases prostate cancer angiogenesis and lymphangiogenesis Research Paper

Zeyad D Nassar, Hyeongsun Moon, Tam Duong, LiQi Neo, Michelle M Hill, Mathias Francois, Robert G Parton, Marie-Odile Parat

Published Oct 4, 2013 · Vol. 4, No. 10 · pp. 1844-1855

Keywords: PTRF, Caveolae, Angiogenesis, Lymphangiogenesis, Prostate Cancer

p53 regulates the transcription of the anti-inflammatory molecule developmental endothelial locus-1 (Del-1) Research Paper

Hyesoon Kim, Seung-Hwan Lee, Mi-Ni Lee, Goo Taeg Oh, Kyung-Chul Choi, Eun Young Choi

Published Oct 3, 2013 · Vol. 4, No. 11 · pp. 1976-1985

Keywords: p53, inflammation, endothelial cell, Del-1

Cholesterol-induced mammary tumorigenesis is enhanced by adiponectin deficiency: role of LDL receptor upregulation Research Paper

Jing Liu, Aimin Xu, Karen Siu-Ling Lam, Nai-Sum Wong, Jie Chen, Peter R R Shepherd, Yu Wang

Published Oct 1, 2013 · Vol. 4, No. 10 · pp. 1804-1818

Keywords: Adiponectin, breast cancer, autophagy, cholesterol, LDLR

Upregulation of adenylate cyclase 3 (ADCY3) increases the tumorigenic potential of cells by activating the CREB pathway Research Paper

Seung-Hyun Hong, Sung-Ho Goh, Sang-Jin Lee, Jung-Ah Hwang, Jieun Lee, Il-Ju Choi, Hyehyun Seo, Jong-Hoon Park, Hiromu Suzuki, Eiichiro Yamamoto, In-Hoo Kim, Jin Sook Jeong, Mi Ha Ju, Dong-Hee Lee, Yeon-Su Lee

Published Sep 30, 2013 · Vol. 4, No. 10 · pp. 1791-1803

Keywords: gastric cancer, adenylate cyclase, tumorigenesis, cAMP/PKA/CREB pathway, promoter methylation

Mode of cell death induced by the HSP90 inhibitor 17-AAG (tanespimycin) is dependent on the expression of pro-apoptotic BAX Research Paper

Marissa V Powers, Melanie Valenti, Susana Mirander, Alison Maloney, Suzanne A Eccles, George Thomas, Paul A Clarke, Paul Workman

Published Sep 29, 2013 · Vol. 4, No. 11 · pp. 1963-1975

Keywords: 17-AAG, HSP90, BAX, Apoptosis, Colon cancer

MYCN is a novel oncogenic target in pediatric T-cell Acute Lymphoblastic Leukemia Research Paper

Annalisa Astolfi, Francesca Vendemini, Milena Urbini, Fraia Melchionda, Riccardo Masetti, Monica Franzoni, Virginia Libri, Salvatore Serravalle, Marco Togni, Giuseppina Paone, Luca Montemurro, Daniela Bressanin, Francesca Chiarini, Alberto M Martelli, Roberto Tonelli, Andrea Pession

Published Sep 29, 2013 · Vol. 5, No. 1 · pp. 120-130

Keywords: pediatric T-ALL, MYCN, peptide nucleic acid, TAL1

Identification of novel small molecule inhibitors of centrosome clustering in cancer cells Research Paper

Eiko Kawamura, Andrew B. Fielding, Nagarajan Kannan, Aruna Balgi, Connie J. Eaves, Michel Roberge, Shoukat Dedhar

Published Sep 25, 2013 · Vol. 4, No. 10 · pp. 1763-1776

Keywords: centrosome clustering, multipolar mitosis, small molecule, cancer specific, spindle

CCAT2, a novel long non-coding RNA in breast cancer: expression study and clinical correlations Research Paper

Roxana S Redis, Anieta M Siewerts, Maxime P Look, Oana Tudoran, Cristina Ivan, Riccardo Spizzo, Xinna Zhang, Vanja de Weerd, Masayoshi Shimizu, Hui Ling, Rares Buiga, Victor Pop, Alexandru Irimie, Riccardo Fodde, Isabella Bedrosian, John WM Martens, John A Foekens, Ioana Berindan-Neagoe, George A Calin

Published Sep 18, 2013 · Vol. 4, No. 10 · pp. 1748-1762

Keywords: non coding RNA, CCAT2, breast cancer, prognosis, real-time PCR

Identification of novel tumor suppressor proteases by degradome profiling of colorectal carcinomas Research Paper

Julia M. Fraile, Gonzalo R. OrdoÃ±ez, Pedro M. Quiros, Aurora Astudillo, Jose A. Galvan, Dolors Colomer, Carlos Lopez-Otin, Jose M.P. Freije, Xose S. Puente

Published Sep 15, 2013 · Vol. 4, No. 11 · pp. 1919-1932

Keywords: proteolysis, metastasis, invasion, cancer

HoxA9 regulated Bcl-2 expression mediates survival of myeloid progenitors and the severity of HoxA9-dependent leukemia Research Paper

Gabriela Brumatti, Marika Salmanidis, Chung H Kok, Rebecca A Bilardi, Jarrod J Sandow, Natasha Silke, Kylie Manson, Jolanda Visser, Anissa M Jabbour, Stefan P Glaser, Toru Okamoto, Philippe Bouillet, Richard J D'Andrea, Paul G Ekert

Published Sep 15, 2013 · Vol. 4, No. 11 · pp. 1933-1947

Keywords: HoxA9, Bcl-2, Leukemia, apoptosis

Substantial expression of luteinizing hormone-releasing hormone (LHRH) receptor type I in human uveal melanoma Research Paper

Andrea Treszl, Zita Steiber, Andrew V Schally, Norman L Block, Balazs Dezso, Gabor Olah, Bernadett Rozsa, Klara Fodor, Armin Buglyo, Janos Gardi, Andras Berta, Gabor Halmos

Published Sep 10, 2013 · Vol. 4, No. 10 · pp. 1721-1728

Keywords: uveal melanoma, luteinizing hormone-releasing hormone (LHRH) receptor

Regulation of histone H2A.Z expression is mediated by sirtuin 1 in prostate cancer Research Paper

Tiago Baptista, InÃªs GraÃ§a, Elsa J Sousa, Ana I Oliveira, NatÃ¡lia R Costa, Pedro Costa-Pinheiro, Francisco Amado, Rui Henrique, Carmen Jeronimo

Published Aug 29, 2013 · Vol. 4, No. 10 · pp. 1673-1685

Keywords: Prostate cancer, H2A.Z, sirtuin 1, epigenetic drugs

The AKT Inhibitor MK-2206 is Cytotoxic in Hepatocarcinoma Cells Displaying Hyperphosphorylated AKT-1 and Synergizes with Conventional Chemotherapy Research Paper

Carolina Simioni, Alberto M. Martelli, Alice Cani, Rengul Cetin-Atalay, James A. McCubrey, Silvano Capitani, Luca M. Neri

Published Aug 24, 2013 · Vol. 4, No. 9 · pp. 1496-1506

Keywords: Hepatocellular carcinoma, MK-2206, Akt-1, targeted therapy, apoptosis, autophagy

Galectin-7 is epigenetically-regulated tumor suppressor in gastric cancer Research Paper

Seok-Jun Kim, Jung-Ah Hwang, Jae Y. Ro, Yeon-Su Lee, Kyung-Hee Chun

Published Aug 20, 2013 · Vol. 4, No. 9 · pp. 1461-1471

Keywords: Galectin-7, Gastric cancer, DNA hypermethylation, Epigenetic mechanisms

Secretome from senescent melanoma engages the STAT3 pathway to favor reprogramming of naive melanoma towards a tumor-initiating cell phenotype. Research Paper

MickaÃ«l Ohanna, Yann Cheli, Caroline Bonet, Vanessa F Bonazzi, Marylin Allegra, Sandy Giuliano, Karine Bille, Philippe Bahadoran, Damien Giacchero, Jean Philippe Lacour, Glen M Boyle, Nicholas F Hayward, Corine Bertolotto, Robert Ballotti

Published Aug 19, 2013 · Vol. 4, No. 12 · pp. 2212-2224

Keywords: melanoma, senescence, secretome, STAT3

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Alterations of immune response of non-small cell lung cancer with Azacytidine Research Paper

Reduction of MLH1 and PMS2 confers temozolomide resistance and is associated with recurrence of glioblastoma Research Paper

NFkB disrupts tissue polarity in 3D by preventing integration of microenvironmental signals Research Paper

Lysine-specific modifications of p53: a matter of life and death? Review

Chemoresistance to gemcitabine in hepatoma cells induces epithelial-mesenchymal transition and involves activation of PDGF-D pathway Research Paper

PTRF/Cavin-1 decreases prostate cancer angiogenesis and lymphangiogenesis Research Paper

p53 regulates the transcription of the anti-inflammatory molecule developmental endothelial locus-1 (Del-1) Research Paper

Cholesterol-induced mammary tumorigenesis is enhanced by adiponectin deficiency: role of LDL receptor upregulation Research Paper

Upregulation of adenylate cyclase 3 (ADCY3) increases the tumorigenic potential of cells by activating the CREB pathway Research Paper

Mode of cell death induced by the HSP90 inhibitor 17-AAG (tanespimycin) is dependent on the expression of pro-apoptotic BAX Research Paper

MYCN is a novel oncogenic target in pediatric T-cell Acute Lymphoblastic Leukemia Research Paper

Identification of novel small molecule inhibitors of centrosome clustering in cancer cells Research Paper

CCAT2, a novel long non-coding RNA in breast cancer: expression study and clinical correlations Research Paper

Identification of novel tumor suppressor proteases by degradome profiling of colorectal carcinomas Research Paper

HoxA9 regulated Bcl-2 expression mediates survival of myeloid progenitors and the severity of HoxA9-dependent leukemia Research Paper

Substantial expression of luteinizing hormone-releasing hormone (LHRH) receptor type I in human uveal melanoma Research Paper

Regulation of histone H2A.Z expression is mediated by sirtuin 1 in prostate cancer Research Paper

The AKT Inhibitor MK-2206 is Cytotoxic in Hepatocarcinoma Cells Displaying Hyperphosphorylated AKT-1 and Synergizes with Conventional Chemotherapy Research Paper

Galectin-7 is epigenetically-regulated tumor suppressor in gastric cancer Research Paper

Secretome from senescent melanoma engages the STAT3 pathway to favor reprogramming of naive melanoma towards a tumor-initiating cell phenotype. Research Paper

Publication Alerts

European Cancer and Oncology Congress

Oncoscience

Post-Publication Promotion

Search Oncotarget

Alterations of immune response of non-small cell lung cancer with Azacytidine Research Paper

Reduction of MLH1 and PMS2 confers temozolomide resistance and is associated with recurrence of glioblastoma Research Paper

NFkB disrupts tissue polarity in 3D by preventing integration of microenvironmental signals Research Paper

Lysine-specific modifications of p53: a matter of life and death? Review

Chemoresistance to gemcitabine in hepatoma cells induces epithelial-mesenchymal transition and involves activation of PDGF-D pathway Research Paper

PTRF/Cavin-1 decreases prostate cancer angiogenesis and lymphangiogenesis Research Paper

p53 regulates the transcription of the anti-inflammatory molecule developmental endothelial locus-1 (Del-1) Research Paper

Cholesterol-induced mammary tumorigenesis is enhanced by adiponectin deficiency: role of LDL receptor upregulation Research Paper

Upregulation of adenylate cyclase 3 (ADCY3) increases the tumorigenic potential of cells by activating the CREB pathway Research Paper

Mode of cell death induced by the HSP90 inhibitor 17-AAG (tanespimycin) is dependent on the expression of pro-apoptotic BAX Research Paper

MYCN is a novel oncogenic target in pediatric T-cell Acute Lymphoblastic Leukemia Research Paper

Identification of novel small molecule inhibitors of centrosome clustering in cancer cells Research Paper

CCAT2, a novel long non-coding RNA in breast cancer: expression study and clinical correlations Research Paper

Identification of novel tumor suppressor proteases by degradome profiling of colorectal carcinomas Research Paper

HoxA9 regulated Bcl-2 expression mediates survival of myeloid progenitors and the severity of HoxA9-dependent leukemia Research Paper

Substantial expression of luteinizing hormone-releasing hormone (LHRH) receptor type I in human uveal melanoma Research Paper

Regulation of histone H2A.Z expression is mediated by sirtuin 1 in prostate cancer Research Paper

The AKT Inhibitor MK-2206 is Cytotoxic in Hepatocarcinoma Cells Displaying Hyperphosphorylated AKT-1 and Synergizes with Conventional Chemotherapy Research Paper

Galectin-7 is epigenetically-regulated tumor suppressor in gastric cancer Research Paper

Secretome from senescent melanoma engages the STAT3 pathway to favor reprogramming of naive melanoma towards a tumor-initiating cell phenotype. Research Paper